J Rychik


Affiliation: The Children's Hospital of Philadelphia
Country: USA


  1. Rychik J, Goff D, McKay E, Mott A, Tian Z, Licht D, et al. Characterization of the Placenta in the Newborn with Congenital Heart Disease: Distinctions Based on Type of Cardiac Malformation. Pediatr Cardiol. 2018;39:1165-1171 pubmed publisher
    ..Fetal Doppler does not correlate with these abnormalities. Studies investigating the relationship between placental abnormalities and postnatal outcomes may offer insight into the fetal origins of outcome variability in CHD. ..
  2. Rychik J. Protein-losing enteropathy after Fontan operation. Congenit Heart Dis. 2007;2:288-300 pubmed publisher
    ..A paradigm for the clinical management of PLE after Fontan operation is proposed. ..
  3. Rychik J, Szwast A, Natarajan S, Quartermain M, Donaghue D, Combs J, et al. Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: a 5-year single institutional experience. Ultrasound Obstet Gynecol. 2010;36:465-70 pubmed publisher
    ..One-third have additional risk factors that limit survival outcome, however two-thirds do not and have an excellent chance of early survival. ..
  4. Rychik J, McCann M, Tian Z, Bebbington M, Johnson M. Fetal cardiovascular effects of lower urinary tract obstruction with giant bladder. Ultrasound Obstet Gynecol. 2010;36:682-6 pubmed publisher
    ..LUTO with giant urinary bladder compresses the iliac arteries, which may lead to increased afterload. Further study is warranted to examine the impact of fetal treatment such as bladder drainage on these cardiovascular parameters. ..
  5. Rychik J, Veldtman G, Rand E, Russo P, Rome J, Krok K, et al. The precarious state of the liver after a Fontan operation: summary of a multidisciplinary symposium. Pediatr Cardiol. 2012;33:1001-12 pubmed publisher
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    Rychik J, Rome J, Collins M, Decampli W, Spray T. The hypoplastic left heart syndrome with intact atrial septum: atrial morphology, pulmonary vascular histopathology and outcome. J Am Coll Cardiol. 1999;34:554-60 pubmed
    ..Maldevelopment of the pulmonary vasculature contributes to the high mortality seen. Atrial morphology can be used as a marker for the severity of pulmonary vascular disease. ..
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    Rychik J. Hypoplastic left heart syndrome: from in-utero diagnosis to school age. Semin Fetal Neonatal Med. 2005;10:553-66 pubmed
    ..New therapies and treatments will certainly arise to meet the challenges these children face as they enter into adulthood, and as our understanding of this unique cardiovascular state progresses. ..
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    Rychik J, Tian Z, Bebbington M, Xu F, McCann M, Mann S, et al. The twin-twin transfusion syndrome: spectrum of cardiovascular abnormality and development of a cardiovascular score to assess severity of disease. Am J Obstet Gynecol. 2007;197:392.e1-8 pubmed
    ..65). We describe the spectrum of cardiovascular abnormalities that are seen in twin-twin transfusion syndrome and propose a scoring system for assessment of severity. ..
  9. Davey B, Rychik J. The Natural History of Atrioventricular Valve Regurgitation Throughout Fetal Life in Patients with Atrioventricular Canal Defects. Pediatr Cardiol. 2016;37:50-4 pubmed publisher
    ..These findings have implications for the counseling, follow-up, and delivery plans of the fetus with AVC defect. ..

More Information


  1. Patel J, Loomes K, Goldberg D, Mercer Rosa L, Dodds K, Rychik J. Early Impact of Fontan Operation on Enteric Protein Loss. Ann Thorac Surg. 2016;101:1025-30 pubmed publisher
    ..However, increased enteric protein loss may occur in children before or after a Fontan operation, particularly when hemodynamic disturbances are present. ..
  2. Rychik J, Khalek N, Gaynor J, Johnson M, Adzick N, Flake A, et al. Fetal intrapericardial teratoma: natural history and management including successful in utero surgery. Am J Obstet Gynecol. 2016;215:780.e1-780.e7 pubmed publisher
    ..Surgical resection in utero is possible, with good results. ..
  3. D Udekem Y, Rychik J. Towards the goal of achieving a normal duration and quality of life after Fontan operation: Creation of the International Fontan Interest group (I-FIG), an international collaborative initiative dedicated to improving outcomes. Int J Cardiol. 2017;245:131-134 pubmed publisher
    ..We intend to build a large platform which will attract researchers of other specialties such as gastro-enterology, neurology and psychology and reach in the field of genomics, molecular biology, pharmacology and bio-informatics. ..
  4. Rychik J. The Relentless Effects of the Fontan Paradox. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016;19:37-43 pubmed publisher
    ..More detailed characterization and understanding of these end-organ complications is necessary to contribute to the goal of achieving a normal duration and quality of life for these unique individuals. ..
  5. Cao L, Tian Z, Rychik J. Prenatal Echocardiographic Predictors of Postnatal Management Strategy in the Fetus with Right Ventricle Hypoplasia and Pulmonary Atresia or Stenosis. Pediatr Cardiol. 2017;38:1562-1568 pubmed publisher