J Rychik

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi Maternal psychological stress after prenatal diagnosis of congenital heart disease
    Jack Rychik
    Fetal Heart Program at the Cardiac Center at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr 162:302-7.e1. 2013
  2. ncbi Speckle tracking-derived myocardial tissue deformation imaging in twin-twin transfusion syndrome: differences in strain and strain rate between donor and recipient twins
    Jack Rychik
    The Fetal Heart Program, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 32:131-7. 2012
  3. ncbi The precarious state of the liver after a Fontan operation: summary of a multidisciplinary symposium
    Jack Rychik
    Division of Cardiology, Single Ventricle Survivorship Program, The Cardiac Center at Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatr Cardiol 33:1001-12. 2012
  4. ncbi Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: a 5-year single institutional experience
    J Rychik
    Fetal Heart Program, The Cardiac Center, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 36:465-70. 2010
  5. ncbi Fetal cardiovascular effects of lower urinary tract obstruction with giant bladder
    J Rychik
    Fetal Heart Program, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 36:682-6. 2010
  6. ncbi Acute cardiovascular effects of fetal surgery in the human
    Jack Rychik
    Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 110:1549-56. 2004
  7. ncbi Fetal cardiovascular physiology
    J Rychik
    The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19004, USA
    Pediatr Cardiol 25:201-9. 2004
  8. ncbi Frontiers in fetal cardiovascular disease
    Jack Rychik
    Fetal Heart Program, The Cardiac Center at The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatr Clin North Am 51:1489-502, vii. 2004
  9. ncbi Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus
    J R Kaltman
    Fetal Heart Program at The Cardiac Center, Division of Cardiology, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 25:32-6. 2005
  10. ncbi Protein-losing enteropathy after Fontan operation
    Jack Rychik
    The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Congenit Heart Dis 2:288-300. 2007

Detail Information

Publications77

  1. ncbi Maternal psychological stress after prenatal diagnosis of congenital heart disease
    Jack Rychik
    Fetal Heart Program at the Cardiac Center at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr 162:302-7.e1. 2013
    ..To determine whether prenatal diagnosis of congenital heart disease (CHD) increases maternal stress...
  2. ncbi Speckle tracking-derived myocardial tissue deformation imaging in twin-twin transfusion syndrome: differences in strain and strain rate between donor and recipient twins
    Jack Rychik
    The Fetal Heart Program, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 32:131-7. 2012
    ..Myocardial tissue deformation analysis using vector velocity imaging is an angle-independent, speckle-tracking technique which can assess myocardial mechanics and may provide insight into cardiac dysfunction in TTTS...
  3. ncbi The precarious state of the liver after a Fontan operation: summary of a multidisciplinary symposium
    Jack Rychik
    Division of Cardiology, Single Ventricle Survivorship Program, The Cardiac Center at Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatr Cardiol 33:1001-12. 2012
    ..At the completion of the symposium, a consensus recommendation was made by the authors' group to pursue a new prospective protocol for clinical evaluation of the liver for all patients in our practice 10 years after the Fontan operation...
  4. ncbi Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: a 5-year single institutional experience
    J Rychik
    Fetal Heart Program, The Cardiac Center, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 36:465-70. 2010
    ..Our goal was to establish the benchmark for perinatal and early surgical outcome in the current era, from a center with an aggressive surgical approach and a cohort with a high level of intention-to-treat...
  5. ncbi Fetal cardiovascular effects of lower urinary tract obstruction with giant bladder
    J Rychik
    Fetal Heart Program, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 36:682-6. 2010
    ..The impact of LUTO on the fetal cardiovascular system has not previously been investigated. We hypothesize that a giant, distended bladder within the pelvis may cause vascular compression with observable consequences...
  6. ncbi Acute cardiovascular effects of fetal surgery in the human
    Jack Rychik
    Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 110:1549-56. 2004
    ..The indications for fetal surgery continue to expand, yet little is known about the acute sequelae of fetal surgery on the human cardiovascular system...
  7. ncbi Fetal cardiovascular physiology
    J Rychik
    The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19004, USA
    Pediatr Cardiol 25:201-9. 2004
    ..Echocardiography has improved our understanding of human fetal cadiovasvular physiology in the normal and diseased states, and has expanded our capability to more effectively treat these disease processes...
  8. ncbi Frontiers in fetal cardiovascular disease
    Jack Rychik
    Fetal Heart Program, The Cardiac Center at The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatr Clin North Am 51:1489-502, vii. 2004
    ....
  9. ncbi Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus
    J R Kaltman
    Fetal Heart Program at The Cardiac Center, Division of Cardiology, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 25:32-6. 2005
    ..We sought to determine whether left- and right-sided obstructive congenital heart lesions modify cerebrovascular flow dynamics in the fetus...
  10. ncbi Protein-losing enteropathy after Fontan operation
    Jack Rychik
    The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Congenit Heart Dis 2:288-300. 2007
    ..A paradigm for the clinical management of PLE after Fontan operation is proposed...
  11. ncbi The twin-twin transfusion syndrome: spectrum of cardiovascular abnormality and development of a cardiovascular score to assess severity of disease
    Jack Rychik
    Fetal Heart Program, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Obstet Gynecol 197:392.e1-8. 2007
    ..Current means of grading twin-twin transfusion syndrome does not characterize cardiovascular aspects adequately. We sought to develop a score that describes the magnitude of cardiovascular severity in twin-twin transfusion syndrome...
  12. ncbi Hypoplastic left heart syndrome: from in-utero diagnosis to school age
    Jack Rychik
    Fetal Heart Program, The Cardiac Center at The Children s Hospital of Philadelphia, and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Semin Fetal Neonatal Med 10:553-66. 2005
    ..New therapies and treatments will certainly arise to meet the challenges these children face as they enter into adulthood, and as our understanding of this unique cardiovascular state progresses...
  13. ncbi Assessment of pulmonary/systemic blood flow ratio after first-stage palliation for hypoplastic left heart syndrome: development of a new index with the use of doppler echocardiography
    J Rychik
    Divisions of Cardiology and Cardiothoracic Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Thorac Cardiovasc Surg 120:81-7. 2000
    ....
  14. ncbi The hypoplastic left heart syndrome with intact atrial septum: atrial morphology, pulmonary vascular histopathology and outcome
    J Rychik
    Cardiac Center at The Children s Hospital of Philadelphia, and Department of Pediatrics, The University of Pennsylvania School of Medicine, USA
    J Am Coll Cardiol 34:554-60. 1999
    ....
  15. ncbi Impact of altered loading conditions on ventricular performance in fetuses with congenital cystic adenomatoid malformation and twin-twin transfusion syndrome
    A Szwast
    Department of Pediatrics, Cardiology Division, Fetal Heart Program, Children s Hospital of Philadelphia, Philadelphia, PA 19050, USA
    Ultrasound Obstet Gynecol 30:40-6. 2007
    ..those in normal fetuses...
  16. ncbi Tricuspid valve dysplasia with severe tricuspid regurgitation: fetal pulmonary artery size predicts lung viability in the presence of small lung volumes
    A T Nathan
    Cardiac Center, Children s Hospital of Philadelphia, University of Pennsylvania, 19104, USA
    Fetal Diagn Ther 27:101-5. 2010
    ....
  17. ncbi Outcome following single-stage repair of coarctation with ventricular septal defect
    J W Gaynor
    Divisions of Pediatric Cardiothoracic Surgery and Pediatric Cardiology, The Cardiac Center, The Children s Hospital of Philadelphia, 34th Street and Civic Center Blvd, Suite 8527, Philadelphia, PA 19104, USA
    Eur J Cardiothorac Surg 18:62-7. 2000
    ..The current study was undertaken to determine outcome and need for reintervention following single-stage repair of coarctation and VSD at our institution...
  18. ncbi Diagnostic assessment before Fontan operation in patients with bidirectional cavopulmonary anastomosis: are noninvasive methods sufficient?
    Pamela S Ro
    Division of Cardiology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 44:184-7. 2004
    ..This study was designed to determine if a subset of patients who have undergone bidirectional cavopulmonary anastomosis could be identified in which catheterization was of little benefit before completion of the Fontan procedure...
  19. ncbi Fetal pulmonary venous Doppler patterns in hypoplastic left heart syndrome: relationship to atrial septal restriction
    K Chintala
    Division of Cardiology, Children s Hospital of Michigan, Wayne State University, Detroit, Michigan 48201, USA
    Heart 94:1446-9. 2008
    ..The objective of this study was to define PVD patterns in HLHS fetuses with an unrestricted or patent foramen ovale (pFO)...
  20. ncbi Late surgical fenestration for complications after the Fontan operation
    J Rychik
    Division of Cardiology, Children s Hospital of Philadelphia 19104, USA
    Circulation 96:33-6. 1997
    ..Initial creation of a fenestration results in less morbidity and mortality; however, the role of late creation of a fenestration in aiding patients manifesting morbidity after an initial nonfenestrated Fontan operation is unclear...
  21. ncbi Thrombus formation after the Fontan operation
    P D Coon
    Cardiac Center at The Children's Hospital of Philadelphia, PA 19104, USA
    Ann Thorac Surg 71:1990-4. 2001
    ..Our study suggests that thrombus formation is inherent to the physiology after Fontan operation and is not related to the type of modification performed...
  22. ncbi Acute changes in preload, afterload, and systolic function after superior cavopulmonary connection
    M T Donofrio
    Department of Pediatrics, The Children s Hospital of Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 65:503-8. 1998
    ..Superior cavopulmonary connection reduces the volume work of the single ventricle...
  23. ncbi Outcome following tricuspid valve detachment for ventricular septal defects closure
    J W Gaynor
    Division of Pediatric Cardiothoracic Surgery, The Cardiac Center at The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 19104, Philadelphia, PA, USA
    Eur J Cardiothorac Surg 19:279-82. 2001
    ....
  24. ncbi Quantitative echocardiographic assessment of the performance of the functionally single right ventricle after the Fontan operation
    W T Mahle
    Division of Cardiology, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA
    Cardiol Young 11:399-406. 2001
    ..Use of the echocardiographic techniques provide insight into ventricular mechanics in patients with functionally single ventricles, and may be valuable tools for serial quantitative follow-up...
  25. ncbi Deviation of atrial septum primum in association with normal left atrioventricular valve size
    M S Cohen
    Cardiac Center at The Children s Hospital of Philadelphia, PA, USA
    J Am Soc Echocardiogr 14:732-7. 2001
    ..Superoposterior DASP carries less physiologic consequence. Echocardiography can distinguish this anomaly from other forms of left atrial obstruction...
  26. ncbi Strategies to treat protein-losing enteropathy
    Jack Rychik
    Divisions of Cardiology and Cardiothoracic Surgery, The Cardiac Center at The Children's Hospital of Philadelphia, PA 19104, USA
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 5:3-11. 2002
    ....
  27. ncbi Using health-related quality of life measures to predict cardiac function in survivors exposed to anthracyclines
    Jill P Ginsberg
    Department of Pediatrics, Center for Outcomes Research, The Children's Hospital of Philadelphia, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA
    J Clin Oncol 22:3149-55. 2004
    ..Patient history appears to be no substitute for cardiac testing in this cohort...
  28. ncbi Atrioventricular valve regurgitation in patients with single ventricle: impact of the bidirectional cavopulmonary anastomosis
    W T Mahle
    Division of Cardiology, The Children s Hospital of Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 72:831-5. 2001
    ..It is not known whether atrioventricular valve regurgitation (AVVR) can improve in some patients after the bidirectional cavopulmonary anastomosis (BCPA) without undertaking concomitant valvuloplasty...
  29. ncbi Evaluation and follow-up of patients with left ventricular apical to aortic conduits with 2D and 3D magnetic resonance imaging and Doppler echocardiography: A new look at an old operation
    M A Fogel
    Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, 34th Street and Civic Center Blvd, Philadelphia, PA 19104, USA
    Am Heart J 141:630-6. 2001
    ..In a patient with an unobstructed conduit, no gradient should exist across the native LVOT...
  30. ncbi Recurrent arch obstruction after repair of isolated coarctation of the aorta in neonates and young infants: is low weight a risk factor?
    D B McElhinney
    Division of Pediatric Cardiothoracic Surgery, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, USA
    J Thorac Cardiovasc Surg 122:883-90. 2001
    ..To determine whether low weight was a risk factor for recurrent arch obstruction, we reviewed our experience with coarctation repair via left thoracotomy in infants less than 3 months of age...
  31. ncbi Aortic morphometry and microcephaly in hypoplastic left heart syndrome
    Amanda J Shillingford
    Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Cardiol Young 17:189-95. 2007
    ..Microcephaly was associated with a small ascending aorta, but not a small transverse aortic arch. Impairment of somatic growth may be an additional factor in the development of microcephaly in these neonates...
  32. ncbi Guidelines for the outpatient management of complex congenital heart disease
    Gil Wernovsky
    Division of Pediatric Cardiology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Congenit Heart Dis 1:10-26. 2006
    ..The purpose of this position article is to provide a framework for outpatient follow-up of complex congenital heart disease, based on a review of current literature and the experience of the authors...
  33. ncbi Outcome of high-risk neonates with congenital complete heart block paced in the first 24 hours after birth
    Andrew C Glatz
    The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    J Thorac Cardiovasc Surg 136:767-73. 2008
    ..The purpose of this study is to assess outcomes of patients with congenital complete heart block who were paced in the first 24 hours after birth owing to the presence of known risk factors...
  34. ncbi Vasoreactive response to maternal hyperoxygenation in the fetus with hypoplastic left heart syndrome
    Anita Szwast
    The Fetal Heart Program at Cardiac Center at The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Circ Cardiovasc Imaging 3:172-8. 2010
    ..Responsiveness of the pulmonary vasculature to maternal hyperoxygenation (MH) may provide a tool to assess the degree of pulmonary vasculopathy present before birth...
  35. ncbi Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcome
    R Douglas Wilson
    Fetal Heart Program, The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 25:15-20. 2009
    ..Prenatal surveillance and growth characteristics are evaluated in a cohort of fetuses with sacrococcygeal teratomas (SCT) as part of risk assessment...
  36. ncbi A randomized trial of prenatal versus postnatal repair of myelomeningocele
    N Scott Adzick
    Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    N Engl J Med 364:993-1004. 2011
    ..Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of in utero repair with standard postnatal repair...
  37. ncbi Right ventricular performance in the fetus with hypoplastic left heart syndrome
    Anita Szwast
    The Fetal Heart Program, Cardiac Center, Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 87:1214-9. 2009
    ..In addition, we sought to determine whether the presence or absence of a left ventricular cavity impacts on RV performance in fetal life...
  38. ncbi Left ventricle to right ventricle size discrepancy in the fetus: the presence of critical congenital heart disease can be reliably predicted
    Michael D Quartermain
    The Cardiac Center at The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Am Soc Echocardiogr 22:1296-301. 2009
    ..Prenatal ventricular size discrepancy with disproportionately smaller left ventricle than right ventricle (L-R/VD) can be a marker for important left-sided structural heart disease in the newborn...
  39. ncbi Right aortic arch and coarctation: a rare association
    Fraz A Ismat
    Division of Cardiology, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Congenit Heart Dis 1:217-23. 2006
    ..Understand anatomical and clinical correlatives to coarctation in right aortic arch...
  40. ncbi Heterotaxy syndrome with functional single ventricle: does prenatal diagnosis improve survival?
    Meryl S Cohen
    Division of Cardiology, The Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 82:1629-36. 2006
    ..Prenatal identification of heterotaxy syndrome may improve long-term survival...
  41. ncbi Improving outcomes in functional single ventricle and total anomalous pulmonary venous connection
    Andrew J Lodge
    Division of Cardiothoracic Surgery, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 78:1688-95. 2004
    ..A review of our recent experience was undertaken to determine whether results in these patients are improving...
  42. ncbi Enalapril to prevent cardiac function decline in long-term survivors of pediatric cancer exposed to anthracyclines
    Jeffrey H Silber
    Center for Outcomes Research, Children s Hospital of Philadelphia, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA
    J Clin Oncol 22:820-8. 2004
    ....
  43. ncbi Selenium deficiency associated with cardiomyopathy: a complication of the ketogenic diet
    A G Christina Bergqvist
    Division of Neurology, The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Epilepsia 44:618-20. 2003
    ..The KD is known to be deficient in most vitamins and minerals and may be deficient in trace minerals. We report biochemical selenium deficiency in nine patients on the KD, including one who developed cardiomyopathy...
  44. ncbi Parental decision-making in congenital heart disease
    K Sarah Hoehn
    Division of Critical Care Medicine, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Cardiol Young 14:309-14. 2004
    ..To explore whether prenatal diagnosis of congenital heart disease is associated with lower levels of parental distress and greater satisfaction with decisions about cardiothoracic surgery when compared to postnatal diagnosis...
  45. ncbi Relation of mesenteric vascular resistance after Fontan operation and protein-losing enteropathy
    Jack Rychik
    The Cardiac Center at The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Cardiol 90:672-4. 2002
  46. ncbi Preliminary investigations into a new method of functional assessment of the fetal heart using a novel application of 'real-time' cardiac magnetic resonance imaging
    Mark A Fogel
    Division of Cardiology, Department of Pediatrics, University of Pennsylvania School of Medicine, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:475-80. 2005
    ..Because of quantitative echocardiographic limitations of fetal ventricular volumes as well as poor windows, we sought to determine if real-time magnetic resonance imaging (MRI) could be used...
  47. ncbi Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia
    Meryl S Cohen
    Cardiac Center and The Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Pediatr 141:25-30. 2002
    ..2 died; 3 of 6 with an LHR >1.2 survived (Fisher exact test, P =.04). CONCLUSION: Heart disease remains a significant risk factor for death in infants with CDH. The LHR helps predict survival in this high-risk group of patients...
  48. ncbi Rare problems associated with the Fontan circulation
    David J Goldberg
    Division of Cardiology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, United States of America
    Cardiol Young 20:113-9. 2010
    ..Continued collaboration between sub-specialists and between institutions will be required to optimise the care for this group of survivors with functionally univentricular hearts...
  49. ncbi Real-time 3-dimensional echocardiographic imaging of congenital heart disease using matrix-array technology: freehand real-time scanning adds instant morphologic details not well delineated by conventional 2-dimensional imaging
    Mohamed A Seliem
    Cardiac Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Soc Echocardiogr 19:121-9. 2006
    ....
  50. ncbi Usefulness of left ventricular inflow index to predict successful biventricular repair in right-dominant unbalanced atrioventricular canal
    Anita L Szwast
    Division of Cardiology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Am J Cardiol 107:103-9. 2011
    ..We propose incorporation of the LVII into the echocardiographic assessment of these patients...
  51. ncbi Comparative analysis of cerebrovascular resistance in fetuses with single-ventricle congenital heart disease
    A Szwast
    The Fetal Heart Program at Cardiac Center, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Ultrasound Obstet Gynecol 40:62-7. 2012
    ..We sought to determine whether the presence or absence of aortic obstruction impacts cerebrovascular resistance in fetuses with single-ventricle (SV) congenital heart disease (CHD)...
  52. ncbi What factors are important to parents making decisions about neonatal research?
    K S Hoehn
    Department of Anesthesiology and Critical Care Medicine, Children s Hospital of Philadelphia, PA 19104, USA
    Arch Dis Child Fetal Neonatal Ed 90:F267-9. 2005
    ..Although parents of neonates with congenital heart disease are often asked permission for their neonates to participate in research studies, little is known about the factors parents consider when making these decisions...
  53. ncbi Protein-losing enteropathy after fontan operation: investigations into possible pathophysiologic mechanisms
    Adam M Ostrow
    The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 82:695-700. 2006
    ..Targeted investigations of these parameters may provide clues as to the mechanism of onset of PLE after Fontan operation...
  54. ncbi Impact of continuous intraoperative monitoring on outcomes in open fetal surgery
    Sundeep G Keswani
    Center for Fetal Diagnosis and Treatment and Fetal Heart Program at the Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:316-20. 2005
    ..CONCLUSION: Continuous intraoperative fetal monitoring provides real time assessment of fetal hemodynamics which results in changes in intraoperative management. The overall outcomes in these critically ill fetuses have been improved...
  55. ncbi Pulmonary outflow tract obstruction in fetuses with complex congenital heart disease: predicting the need for neonatal intervention
    M D Quartermain
    Fetal Heart Program at The Cardiac Center, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Ultrasound Obstet Gynecol 41:47-53. 2013
    ..To identify prenatal echocardiographic markers that could predict the need for neonatal intervention in fetuses with right ventricular outflow tract obstruction...
  56. ncbi Design and baseline characteristics for the ACE Inhibitor After Anthracycline (AAA) study of cardiac dysfunction in long-term pediatric cancer survivors
    J H Silber
    Division of Pediatric Oncology, Department of Pediatrics, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am Heart J 142:577-85. 2001
    ....
  57. ncbi Hypoplastic left heart syndrome with atrial level restriction in the era of prenatal diagnosis
    Jenifer A Glatz
    Department of Pediatrics, Children s Hospital of Philadelphia and the University Hospital of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 84:1633-8. 2007
    ..We sought to assess the impact of prenatal diagnosis and immediate intervention on the outcome of this high-risk population...
  58. ncbi Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? A case report
    Jennifer B Merriman
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Reprod Med 53:357-9. 2008
    ..Neonatal survival and prognosis are closely linked with development of hydrops in cases of sustained fetal tachycardia. Several antiarrhythmic medications are available for conversion to sinus rhythm...
  59. ncbi Current concepts in fetal cardiovascular disease
    Anita Szwast
    The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Clin Perinatol 32:857-75, viii. 2005
    ..An understanding of the enigmatic process of twin-twin transfusion syndrome may help in elucidating one of the mechanisms for development of cardiac structural abnormalities in the fetus...
  60. ncbi Surgical reinterventions following the Fontan procedure
    Matus Petko
    Division of Cardiothoracic Surgery, The Cardiac Center at The Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Suite 8527, Philadelphia, PA 19104, USA
    Eur J Cardiothorac Surg 24:255-9. 2003
    ..Most reinterventions can be performed with minimal morbidity and mortality. Survival for patients requiring cardiac transplantation following the Fontan procedure remains poor...
  61. ncbi American Society of Echocardiography guidelines and standards for performance of the fetal echocardiogram
    Jack Rychik
    The Children's Hospital of Philadelphia, Philadelphia, PA, USA
    J Am Soc Echocardiogr 17:803-10. 2004
  62. ncbi Diagnosis and management of heart failure in the fetus
    B Davey
    The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Minerva Pediatr 64:471-92. 2012
    ..In this review, we will explore the different mechanisms of heart failure in this unique patient population and highlight the role of fetal echocardiography in the current management of these conditions...
  63. ncbi Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adults
    Bradley S Marino
    Children s Hospital of Philadelphia, Pediatrics Divisions of Cardiology, Philadelphia, PA, USA
    Congenit Heart Dis 3:39-46. 2008
    ....
  64. ncbi Use of oral budesonide in the management of protein-losing enteropathy after the Fontan operation
    Deepika Thacker
    Division of Cardiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Ann Thorac Surg 89:837-42. 2010
    ..Oral controlled-release budesonide is 90% metabolized at first pass through the liver, has high enteric anti-inflammatory activity and relatively low systemic effects, and may be an ideal agent for use in treating this disease...
  65. ncbi Impact of oral sildenafil on exercise performance in children and young adults after the fontan operation: a randomized, double-blind, placebo-controlled, crossover trial
    David J Goldberg
    Division of Cardiology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 123:1185-93. 2011
    ..A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity...
  66. ncbi Critical heart disease in the neonate: presentation and outcome at a tertiary care center
    Aaron T Dorfman
    Department of Pediatrics, Division of Cardiology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 19104, USA
    Pediatr Crit Care Med 9:193-202. 2008
    ..To define the modes of presentation, incidence of major organ dysfunction, predictors of hospital mortality, and adverse outcomes in neonates with critical heart disease admitted to a tertiary care center...
  67. ncbi Parachute mitral valve: morphologic descriptors, associated lesions, and outcomes after biventricular repair
    Bradley S Marino
    Division of Cardiology in the Department of Pediatrics, Anesthesiology and Critical Care, and Surgery in the Cardiac Center at The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Thorac Cardiovasc Surg 137:385-393.e4. 2009
    ....
  68. ncbi Functional status, heart rate, and rhythm abnormalities in 521 Fontan patients 6 to 18 years of age
    Andrew D Blaufox
    Medical University of South Carolina, Charleston, SC, USA
    J Thorac Cardiovasc Surg 136:100-7, 107.e1. 2008
    ..Our objective was to determine the relationship between functional outcome and abnormalities of heart rate and rhythm after the Fontan operation...
  69. ncbi Indications and guidelines for performance of transesophageal echocardiography in the patient with pediatric acquired or congenital heart disease: report from the task force of the Pediatric Council of the American Society of Echocardiography
    Nancy A Ayres
    Texas Children's Hospital, Houston, Texas, USA
    J Am Soc Echocardiogr 18:91-8. 2005
  70. ncbi A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome
    Timothy M Crombleholme
    Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, MLC 2023, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Obstet Gynecol 197:396.e1-9. 2007
    ..The objective of the study was to examine the effect of selective fetoscopic laser photocoagulation (SFLP) vs serial amnioreduction (AR) on perinatal mortality in severe twin-twin transfusion syndrome (TTTS)...
  71. ncbi Prenatally diagnosed fetal lung lesions with associated conotruncal heart defects: is there a genetic association?
    Margaret R Hüsler
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA 19104 4399, USA
    Prenat Diagn 27:1123-8. 2007
    ..Congenital lung malformation can easily be diagnosed by prenatal ultrasound. Associated extrapulmonary malformations such as heart defects and chromosomal aberrations are rare...
  72. ncbi Illustration of the additional value of real-time 3-dimensional echocardiography to conventional transthoracic and transesophageal 2-dimensional echocardiography in imaging muscular ventricular septal defects: does this have any impact on individual patie
    Laura Mercer-Rosa
    Cardiac Center, The Children's Hospital of Philadelphia, Pennsylvania 19104, USA
    J Am Soc Echocardiogr 19:1511-9. 2006
    ..This new imaging modality should be an important adjunct to the standard transthoracic echocardiographic and TEE imaging of these defect before any intervention...
  73. ncbi Abnormalities of intestinal rotation in patients with congenital heart disease and the heterotaxy syndrome
    Barbara Ferdman
    Washington University School of Medicine Pediatrics, St Louis, MO, USA
    Congenit Heart Dis 2:12-8. 2007
    ..Our objective was to determine the prevalence of screening for AIR by elective imaging among our group and prophylactic vs. emergent surgical intervention for AIR in patients with congenital heart disease and heterotaxy syndrome...
  74. ncbi ACC/AHA clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence
    Miguel A Quinones
    J Am Coll Cardiol 41:687-708. 2003
  75. ncbi American College of Cardiology/American Heart Association clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians--American Society of Internal Medicine Ta
    Miguel A Quinones
    Circulation 107:1068-89. 2003
  76. ncbi ACC/AHA clinical competence statement on echocardiography: a report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on clinical competence
    Miguel A Quinones
    J Am Soc Echocardiogr 16:379-402. 2003
  77. ncbi Guidelines and standards for performance of a pediatric echocardiogram: a report from the Task Force of the Pediatric Council of the American Society of Echocardiography
    Wyman W Lai
    Mount Sinai Medical Center, New York, NY 10029, USA
    J Am Soc Echocardiogr 19:1413-30. 2006