David I Rosenthal

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome
    Anna Likhacheva
    Department of Radian Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck Oncol 3:32. 2011
  2. pmc Simple carotid-sparing intensity-modulated radiotherapy technique and preliminary experience for T1-2 glottic cancer
    David I Rosenthal
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 77:455-61. 2010
  3. pmc Early postoperative paclitaxel followed by concurrent paclitaxel and cisplatin with radiation therapy for patients with resected high-risk head and neck squamous cell carcinoma: report of the phase II trial RTOG 0024
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 27:4727-32. 2009
  4. ncbi request reprint Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 101:2567-73. 2004
  5. ncbi request reprint Head and neck squamous cell carcinoma: optimizing the therapeutic index
    David I Rosenthal
    Department of Radiation Oncology, 097, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Expert Rev Anticancer Ther 5:501-14. 2005
  6. doi request reprint Strategies for managing radiation-induced mucositis in head and neck cancer
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Radiat Oncol 19:29-34. 2009
  7. ncbi request reprint Phase I study of Paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced non-small cell lung cancer
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 1:38-45. 2006
  8. doi request reprint Phase I study of preoperative radiation therapy with concurrent infusional 5-fluorouracil and oxaliplatin followed by surgery and postoperative 5-fluorouracil plus leucovorin for T3/T4 rectal adenocarcinoma: ECOG E1297
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 72:108-13. 2008
  9. ncbi request reprint A phase II study to assess the efficacy of amifostine for submandibular/sublingual salivary sparing during the treatment of head and neck cancer with intensity modulated radiation therapy for parotid salivary sparing
    David I Rosenthal
    The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Oncol 31:25-8. 2004
  10. ncbi request reprint Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer
    David I Rosenthal
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:2636-43. 2006

Detail Information

Publications88

  1. pmc Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome
    Anna Likhacheva
    Department of Radian Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck Oncol 3:32. 2011
    ..The impact of tumor differentiation on the behavior and response of sinonasal neuroendocrine carcinoma is unknown...
  2. pmc Simple carotid-sparing intensity-modulated radiotherapy technique and preliminary experience for T1-2 glottic cancer
    David I Rosenthal
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 77:455-61. 2010
    ..To investigate the dosimetry and feasibility of carotid-sparing intensity-modulated radiotherapy (IMRT) for early glottic cancer and to report preliminary clinical experience...
  3. pmc Early postoperative paclitaxel followed by concurrent paclitaxel and cisplatin with radiation therapy for patients with resected high-risk head and neck squamous cell carcinoma: report of the phase II trial RTOG 0024
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 27:4727-32. 2009
    ....
  4. ncbi request reprint Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 101:2567-73. 2004
    ..The authors reviewed their institutional experience to determine whether sinonasal neuroendocrine tumors of different histologies have distinct clinical characteristics that warrant individualized treatment approaches...
  5. ncbi request reprint Head and neck squamous cell carcinoma: optimizing the therapeutic index
    David I Rosenthal
    Department of Radiation Oncology, 097, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Expert Rev Anticancer Ther 5:501-14. 2005
    ..These strategies are reviewed in a clinical context...
  6. doi request reprint Strategies for managing radiation-induced mucositis in head and neck cancer
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Radiat Oncol 19:29-34. 2009
    ..This review focuses on mucositis recognition, patient treatment selection, and RIM symptom-management strategies...
  7. ncbi request reprint Phase I study of Paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced non-small cell lung cancer
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Thorac Oncol 1:38-45. 2006
    ....
  8. doi request reprint Phase I study of preoperative radiation therapy with concurrent infusional 5-fluorouracil and oxaliplatin followed by surgery and postoperative 5-fluorouracil plus leucovorin for T3/T4 rectal adenocarcinoma: ECOG E1297
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 72:108-13. 2008
    ..We performed a Phase I trial to test the safety and preliminary efficacy of adding oxaliplatin to standard preoperative chemoradiation therapy for rectal cancer...
  9. ncbi request reprint A phase II study to assess the efficacy of amifostine for submandibular/sublingual salivary sparing during the treatment of head and neck cancer with intensity modulated radiation therapy for parotid salivary sparing
    David I Rosenthal
    The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Oncol 31:25-8. 2004
    ....
  10. ncbi request reprint Prevention and treatment of dysphagia and aspiration after chemoradiation for head and neck cancer
    David I Rosenthal
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:2636-43. 2006
    ..Specific recommendations are made to promote maintenance and recovery of swallowing function...
  11. ncbi request reprint Consequences of mucositis-induced treatment breaks and dose reductions on head and neck cancer treatment outcomes
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 0097, Houston, TX 77030, USA
    J Support Oncol 5:23-31. 2007
    ..Effective prophylaxis or treatment could reduce the probability of treatment breaks and dose reductions and thus improve outcomes...
  12. ncbi request reprint Importance of patient examination to clinical quality assurance in head and neck radiation oncology
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck 28:967-73. 2006
    ..We determined the value of clinical peer review in radiation therapy for head and neck cancer that involved head and neck examination...
  13. ncbi request reprint Measuring head and neck cancer symptom burden: the development and validation of the M. D. Anderson symptom inventory, head and neck module
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 29:923-31. 2007
    ....
  14. doi request reprint Hypothyroidism in older patients with head and neck cancer after treatment with radiation: a population-based study
    Grace L Smith
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 31:1031-8. 2009
    ..In patients with head and neck cancer, radiation treatment (RT) is a risk factor for hypothyroidism. However, the specific magnitude of risk after RT in older patients is not known...
  15. pmc Prospective imaging assessment of mortality risk after head-and-neck radiotherapy
    Benjamin J Moeller
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 78:667-74. 2010
    ..Unresolved questions include whether functional or anatomic imaging might improve mortality risk assessment for this disease. We addressed these issues in a prospective institutional trial...
  16. doi request reprint Patterns of disease recurrence following treatment of oropharyngeal cancer with intensity modulated radiation therapy
    Adam S Garden
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 85:941-7. 2013
    ..To report mature results of a large cohort of patients diagnosed with squamous cell carcinoma of the oropharynx who were treated with intensity modulated radiation therapy (IMRT)...
  17. doi request reprint Candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy
    David L Schwartz
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 78:1356-65. 2010
    ..To investigate long-term swallowing function in oropharyngeal cancer patients treated with intensity-modulated radiotherapy (IMRT), and to identify novel dose-limiting criteria predictive for dysphagia...
  18. doi request reprint Outcomes of patients with tonsillar carcinoma treated with post-tonsillectomy radiation therapy
    Gokcen Yildirim
    The University of Texas M D Anderson Cancer Center, Department of Radiation Oncology, Unit 97, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck 32:473-80. 2010
    ..Our aim was to evaluate the therapeutic outcomes of patients with squamous cell carcinoma of the tonsil that underwent tonsillectomies followed by radiotherapy...
  19. ncbi request reprint Survival impact of planned restaging and early surgical salvage following definitive chemoradiation for locally advanced squamous cell carcinomas of the oropharynx and hypopharynx
    Sue S Yom
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Clin Oncol 28:385-92. 2005
    ..The authors reviewed the practice of planned post-RT restaging to determine its impact on the success of early surgical salvage...
  20. ncbi request reprint Pilot study of postoperative reirradiation, chemotherapy, and amifostine after surgical salvage for recurrent head-and-neck cancer
    Mitchell Machtay
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 59:72-7. 2004
    ..We designed a prospective protocol to determine the feasibility, toxicity, and preliminary efficacy of a regimen of postoperative reirradiation, chemotherapy and the radioprotector amifostine after salvage head-and-neck surgery...
  21. doi request reprint Intensity-modulated radiotherapy for cervical node squamous cell carcinoma metastases from unknown head-and-neck primary site: M. D. Anderson Cancer Center outcomes and patterns of failure
    Steven J Frank
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 78:1005-10. 2010
    ....
  22. doi request reprint The M. D. Anderson symptom inventory-head and neck module, a patient-reported outcome instrument, accurately predicts the severity of radiation-induced mucositis
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 72:1355-61. 2008
    ....
  23. ncbi request reprint Differential expression of hormonal and growth factor receptors in salivary duct carcinomas: biologic significance and potential role in therapeutic stratification of patients
    Michelle D Williams
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 31:1645-52. 2007
    ....
  24. doi request reprint Unilateral radiotherapy for the treatment of tonsil cancer
    Gregory M Chronowski
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 83:204-9. 2012
    ..D. Anderson Cancer Center with unilateral radiotherapy techniques that irradiate the involved tonsil region and ipsilateral neck only...
  25. doi request reprint Prediction of neck dissection requirement after definitive radiotherapy for head-and-neck squamous cell carcinoma
    Juliette Thariat
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 82:e367-74. 2012
    ....
  26. ncbi request reprint Disease-control rates following intensity-modulated radiation therapy for small primary oropharyngeal carcinoma
    Adam S Garden
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:438-44. 2007
    ....
  27. pmc Parotid gland dose in intensity-modulated radiotherapy for head and neck cancer: is what you plan what you get?
    Jennifer C O'Daniel
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 69:1290-6. 2007
    ..To quantify the differences between planned and delivered parotid gland and target doses, and to assess the benefits of daily bone alignment for head and neck cancer patients treated with intensity-modulated radiotherapy (IMRT)...
  28. doi request reprint Postoperative radiotherapy for advanced medullary thyroid cancer--local disease control in the modern era
    David L Schwartz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 30:883-8. 2008
    ..The purpose of this study is to catalog modern-era postoperative radiotherapy (external beam radiotherapy [EBRT]) outcomes for advanced medullary thyroid cancer...
  29. ncbi request reprint Multiple regions-of-interest analysis of setup uncertainties for head-and-neck cancer radiotherapy
    Lifei Zhang
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:1559-69. 2006
    ..To analyze three-dimensional setup uncertainties for multiple regions of interest (ROIs) in head-and-neck region...
  30. ncbi request reprint Management of nonsinonasal neuroendocrine carcinomas of the head and neck
    Jerry L Barker
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 98:2322-8. 2003
    ..The authors undertook a retrospective study to gain insights into the spectrum of clinicopathologic characteristics, patterns of failure, and optimal management of patients with this disease...
  31. pmc Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century
    Adam S Garden
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Radiat Oncol 8:21. 2013
    ..We performed this study to assess outcomes of patients with oropharyngeal cancer treated with modern therapy approaches...
  32. ncbi request reprint Postoperative radiotherapy for maxillary sinus cancer: long-term outcomes and toxicities of treatment
    Ian J Bristol
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:719-30. 2007
    ..To determine the effects of three changes in radiotherapy technique on the outcomes for patients irradiated postoperatively for maxillary sinus cancer...
  33. ncbi request reprint Final report of a pilot trial of accelerated radiotherapy plus concurrent 96-hour infusional paclitaxel for locally advanced head and neck cancer
    Mary K Bucci
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Am J Clin Oncol 27:595-602. 2004
    ..LRC and survival compare favorably with other aggressive regimens for this poor-prognosis population. Further study of accelerated XRT with concurrent chemotherapy is indicated...
  34. doi request reprint IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes
    Erik P Sulman
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 73:399-409. 2009
    ..Limited data are available regarding the use of intensity-modulated radiotherapy (IMRT) for this indication. We reviewed our initial experience using IMRT for previously irradiated head and neck cancer patients...
  35. doi request reprint Anaplastic thyroid cancer: Clinical outcomes with conformal radiotherapy
    Aarti Bhatia
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 32:829-36. 2010
    ..The aim of this study was to review institutional outcomes for anaplastic thyroid cancer treated with conformal 3-dimensional radiotherapy (3DRT) or intensity-modulated radiotherapy (IMRT)...
  36. doi request reprint Beam path toxicities to non-target structures during intensity-modulated radiation therapy for head and neck cancer
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 72:747-55. 2008
    ..This study estimates the doses and toxicities to nontarget structures during IMRT...
  37. ncbi request reprint The effect of dental artifacts, contrast media, and experience on interobserver contouring variations in head and neck anatomy
    David I Rosenthal
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Oncol 30:191-8. 2007
    ..To investigate interobserver variability in the delineation of head-and-neck (H&N) anatomic structures on CT images, including the effects of image artifacts and observer experience...
  38. ncbi request reprint Effect of initial treatment on disease outcome for patients with submandibular gland carcinoma
    Scott M Kaszuba
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 441, Houston, TX 77030, USA
    Arch Otolaryngol Head Neck Surg 133:546-50. 2007
    ..To elucidate the effect on outcome of initial surgical enucleation with or without definitive surgical resection and radiation therapy for patients with submandibular gland carcinoma...
  39. ncbi request reprint Outcomes after radiotherapy for squamous cell carcinoma of the eyelid
    Janjira Petsuksiri
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:111-8. 2008
    ..Squamous cell carcinoma (SCC) of the eyelid is a rare malignancy with metastatic potential. In the current study, the outcomes of patients with SCC of the eyelid were evaluated after definitive and postoperative radiation therapy...
  40. ncbi request reprint Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system
    Jerry L Barker
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:960-70. 2004
    ..We conducted a pilot study to quantify the magnitude of these anatomic changes with systematic CT imaging...
  41. ncbi request reprint A phase I study of SPI-077 (Stealth liposomal cisplatin) concurrent with radiation therapy for locally advanced head and neck cancer
    David I Rosenthal
    Department of Radiation Oncology, Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Invest New Drugs 20:343-9. 2002
    ..We performed a Phase I study of Stealth liposomal cisplatin (SPI-077) concurrent with RT for head and neck squamous cell carcinoma (HNSCC)...
  42. ncbi request reprint Organ preservation therapy using induction plus concurrent chemoradiation for advanced resectable oropharyngeal carcinoma: a University of Pennsylvania Phase II Trial
    Mitchell Machtay
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    J Clin Oncol 20:3964-71. 2002
    ..To determine the efficacy, feasibility, and toxicity of a new regimen for locally advanced oropharyngeal carcinoma...
  43. doi request reprint Compliance with quality assurance measures in patients treated for early oral tongue cancer
    Amy C Hessel
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:3408-16. 2010
    ..The objective of this study was to identify measurable parameters that provide quality data for assessing how well cancer care adheres to accepted treatment guidelines and is delivered to any given patient with oral tongue cancer...
  44. pmc Postoperative external beam radiotherapy for differentiated thyroid cancer: outcomes and morbidity with conformal treatment
    David L Schwartz
    Department of Radiation Oncology, UT MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 74:1083-91. 2009
    ..To review institutional outcomes for patients treated for differentiated thyroid cancer with postoperative conformal external beam radiotherapy (EBRT)...
  45. ncbi request reprint Two-field versus three-field irradiation technique in the postoperative treatment of head-and-neck cancer
    Sue S Yom
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 66:469-76. 2006
    ..This report compares the clinical outcomes of patients treated with postoperative radiation (PORT) using either 3FT or CTT...
  46. ncbi request reprint Molecular and clinicopathologic comparisons of head and neck squamous carcinoma variants: common and distinctive features of biological significance
    Hong Ran Choi
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 28:1299-310. 2004
    ....
  47. ncbi request reprint Target coverage for head and neck cancers treated with IMRT: review of clinical experiences
    Adam S Garden
    Department of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Semin Radiat Oncol 14:103-9. 2004
    ..This review will focus on how IMRT is being implemented into the treatment of head and neck cancer, specifically with regards to target definition and dosing issues...
  48. ncbi request reprint Radiation therapy for early-stage carcinoma of the oropharynx
    Ugur Selek
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, 77030, USA
    Int J Radiat Oncol Biol Phys 59:743-51. 2004
    ....
  49. doi request reprint Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy
    Grace L Smith
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 26:5119-25. 2008
    ..Cerebrovascular disease is common in head and neck cancer patients, but it is unknown whether radiotherapy increases the cerebrovascular disease risk in this population...
  50. ncbi request reprint Sinonasal adenoid cystic carcinoma: the M. D. Anderson Cancer Center experience
    Allison D Lupinetti
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Cancer 110:2726-31. 2007
    ..The objective of the current study was to evaluate prognostic factors, treatment outcomes, recurrence patterns, and survival rates for sinonasal adenoid cystic carcinoma...
  51. ncbi request reprint Presence of malignant tumor cells in persistent neck disease after radiotherapy for advanced squamous cell carcinoma of the oropharynx is associated with poor survival
    Christian Simon
    Department of Head and Neck Surgery, The University of Texas Anderson Cancer Center, Houston, TX, USA
    Eur Arch Otorhinolaryngol 263:313-8. 2006
    ....
  52. doi request reprint The role of salvage surgery in patients with recurrent squamous cell carcinoma of the oropharynx
    Mark E Zafereo
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77230 1402, USA
    Cancer 115:5723-33. 2009
    ....
  53. ncbi request reprint Preliminary investigation of symptom distress in the head and neck patient population: validation of a measurement instrument
    Heather A Jones
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Clin Oncol 29:158-62. 2006
    ..Thus, the specific aim of this pilot study was to estimate the reliability and validity of a modified version of a symptom distress scale used to assess the qualitative difference in symptom distress between the 2 populations...
  54. ncbi request reprint Parathyroid carcinoma: a 22-year experience
    Naifa L Busaidy
    joint Baylor College of Medicine The University of Texas M D Anderson Cancer Center Training Program in Endocrinology, Diabetes, and Metabolism, Houston, Texas, USA
    Head Neck 26:716-26. 2004
    ..Treatment strategies generally derive from clinical and anecdotal experiences. We report our experience with this entity...
  55. ncbi request reprint New equations for matching a low neck field to oblique upper neck fields with collimator rotation in a 3-field monoisocentric setup for head-and-neck cancers
    Maria A Manske
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Med Dosim 29:86-91. 2004
    ..They predict the necessary manipulations of the LAN boost field to maintain a geometrically precise matchline, as verified by 3D treatment planning software, phantom dosimetry, and actual patient setups...
  56. doi request reprint Comparison of 2D radiographic images and 3D cone beam computed tomography for positioning head-and-neck radiotherapy patients
    Heng Li
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:916-25. 2008
    ..To assess the benefit of patient-specific headrest...
  57. doi request reprint Acupuncture for radiation-induced xerostomia in patients with cancer: a pilot study
    M Kay Garcia
    Integrative Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Head Neck 31:1360-8. 2009
    ..This pilot study evaluated if acupuncture can alleviate radiation-induced xerostomia among patients with cancer. Secondary objectives were to assess the effects of acupuncture on salivary flow and quality of life (QOL)...
  58. doi request reprint Phase II study of palifermin and concurrent chemoradiation in head and neck squamous cell carcinoma
    David M Brizel
    Department of Radiation Oncology, Duke University, Durham, NC, USA
    J Clin Oncol 26:2489-96. 2008
    ..This study assessed the efficacy and safety of palifermin in patients receiving concurrent chemoradiotherapy for advanced head and neck squamous cell carcinoma...
  59. doi request reprint Postoperative adjuvant external-beam radiation therapy for cancers of the eyelid and conjunctiva
    Adam Hsu
    Section of Ophthalmology, and daggerDepartment of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthal Plast Reconstr Surg 24:444-9. 2008
    ..To outline the indications for and our experience with postoperative adjuvant external-beam radiotherapy (EBRT) in patients with eyelid or conjunctival cancers...
  60. doi request reprint Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features
    Mahitosh Mandal
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 112:2088-100. 2008
    ..In the current study, the expressions of several factors associated with the induction of EMT in HNSC cell lines and tumor specimens were investigated to define their functional and pathologic role in HNSC...
  61. ncbi request reprint Impact of changes to the American Joint Committee on Cancer T classification on outcome prediction in patients with oropharyngeal cancer
    Joshua A Asper
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:1950-7. 2006
    ..The efficacy of the current 6th edition of the American Joint Committee on Cancer (AJCC) tumor staging criteria in improving outcome prediction for patients with oropharyngeal cancer was analyzed...
  62. ncbi request reprint Altered radiation therapy fractionation, chemoradiation, and patient selection for the treatment of head and neck squamous carcinoma
    David I Rosenthal
    Department of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Semin Radiat Oncol 14:153-66. 2004
    ..These initiatives will likely lead to improvement in the therapeutic index for patients with HNSCC...
  63. doi request reprint Outcomes of malignant tumors of the lacrimal apparatus: the University of Texas MD Anderson Cancer Center experience
    Heath D Skinner
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Cancer 117:2801-10. 2011
    ..The purpose of this study was to assess treatment outcomes by type of surgery (orbital exenteration vs eye-sparing surgery) and clarify the role of adjuvant RT for this rare disease...
  64. ncbi request reprint Relative risk of stroke in head and neck carcinoma patients treated with external cervical irradiation
    Jeffrey C Haynes
    Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 112:1883-7. 2002
    ..To determine the rate of cerebrovascular events (stroke) in patients irradiated to high doses for squamous cell carcinoma of the head and neck...
  65. ncbi request reprint Controversies in the management of advanced laryngeal squamous cell carcinoma
    Randal S Weber
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:211-9. 2004
  66. doi request reprint Molecular and phenotypic analysis of poorly differentiated sinonasal neoplasms: an integrated approach for early diagnosis and classification
    Brett Cordes
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Pathol 40:283-92. 2009
    ....
  67. ncbi request reprint Genetic analysis of sinonasal adenocarcinoma phenotypes: distinct alterations of histogenetic significance
    Sue S Yom
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Mod Pathol 18:315-9. 2005
    ....
  68. pmc Prospective risk-adjusted [18F]Fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer
    Benjamin J Moeller
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA
    J Clin Oncol 27:2509-15. 2009
    ..We conducted a prospective trial to identify patient populations likely to benefit from the addition of functional imaging to the assessment of radiotherapy response...
  69. ncbi request reprint Does concurrent postoperative radiotherapy and chemotherapy in head and neck cancer improve patient outcome?
    Sue S Yom
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Nat Clin Pract Oncol 1:14-5. 2004
  70. ncbi request reprint Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction
    Anjali K Gupta
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6072, USA
    Clin Cancer Res 8:885-92. 2002
    ..We have shown previously that radioresistance could be conferred via the Ras-PI3K pathway. Here we investigate the contribution of EGFR to this pathway and its impact on treatment outcome...
  71. ncbi request reprint Importance of the treatment package time in surgery and postoperative radiation therapy for squamous carcinoma of the head and neck
    David I Rosenthal
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 2 Donner, Philadelphia, PA 19104, USA
    Head Neck 24:115-26. 2002
    ..Patients were also divided into intermediate- and high-risk groups on the basis of eligibility for RTOG 95-01. Univariate (logrank) and multivariate analyses were performed...
  72. ncbi request reprint Radiation-induced xerostomia
    Mark S Chambers
    Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Head Neck 29:58-63. 2007
    ..Radiation-induced xerostomia is a frequent and usually permanent side effect of radiation therapy for head and neck cancer. We summarize recent developments in the prevention and treatment of radiation-induced xerostomia...
  73. ncbi request reprint Conditional survival in head and neck squamous cell carcinoma: results from the SEER dataset 1973-1998
    Clifton D Fuller
    Department of Radiation Oncology and Graduate Division of Radiological Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Cancer 109:1331-43. 2007
    ..Useful prognostic information for cancer survivors is provided by CS analysis. Estimated baseline CS parameters for HNSCC were sought using large-scale cancer registry data...
  74. ncbi request reprint Differential methylation status of tumor-associated genes in head and neck squamous carcinoma: incidence and potential implications
    Shin ichiro Maruya
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 10:3825-30. 2004
    ..Concurrent methylation analysis of multiple, functionally distinct genes may provide important information on their differential alterations and potential association in head and neck squamous carcinogenesis...
  75. doi request reprint Swallowing outcomes after radiotherapy for laryngeal carcinoma
    Katherine A Hutcheson
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Arch Otolaryngol Head Neck Surg 134:178-83. 2008
    ..To describe swallowing physiology and functional outcomes at select intervals after definitive radiotherapy for laryngeal carcinoma. We also examined associations among patient, tumor, and treatment characteristics and swallowing outcomes...
  76. doi request reprint Sinonasal teratocarcinosarcoma of the head and neck: a report of 10 patients treated at a single institution and comparison with reported series
    Stacey L Smith
    Department of Head and Neck Surgery, The University of Texas Medical School, Houston, TX, USA
    Arch Otolaryngol Head Neck Surg 134:592-5. 2008
    ..Previous reports of these tumors have focused on their differential diagnosis and histogenesis and consisted of individual case reports and consultation based series...
  77. ncbi request reprint A Phase II trial of subcutaneous amifostine and radiation therapy in patients with head-and-neck cancer
    Pramila Rani Anne
    Thomas Jefferson University Hospital, Bodine Center for Cancer Research, Philadelphia, PA 19107, USA
    Int J Radiat Oncol Biol Phys 67:445-52. 2007
    ..Intravenous amifostine 200 mg/m2 reduces xerostomia in head-and-neck cancer patients. This Phase II study evaluated subcutaneous (s.c.) amifostine in a similar patient population...
  78. ncbi request reprint Postoperative treatment intensification for improving outcome in the high-risk patient: an evolutionary process
    Randal S Weber
    Head Neck 27:841-2. 2005
  79. ncbi request reprint Parotidectomy in the treatment of aggressive cutaneous malignancies
    Stephen Y Lai
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, 5 Silverstein Ravdin, 3400 Spruce St, Philadelphia, PA 19104, USA
    Arch Otolaryngol Head Neck Surg 128:521-6. 2002
    ..Aggressive nonmelanoma skin cancer (ANMSC) of the head and neck may require parotidectomy because of neurotropic spread, direct invasion of the parotid gland, or parotid metastasis...
  80. ncbi request reprint Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels
    Amita Shukla-Dave
    Dept of Radiology, University of Pennsylvania Medical Center, Philadelphia, USA
    Acad Radiol 9:688-94. 2002
    ..Frequent regional node involvement facilitates surface coil investigation with phosphorus-31 magnetic resonance spectroscopy...
  81. ncbi request reprint Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cell carcinomas of the larynx or oropharynx: results of Eastern Cooperative Oncology Group Study E2399
    Anthony J Cmelak
    Vanderbilt University Medical Center, Nashville, TN 37232 5671, USA
    J Clin Oncol 25:3971-7. 2007
    ..This phase II multi-institutional trial evaluates taxane-based induction chemotherapy followed by CCR for organ preservation in resectable stage III/IVA and IVB larynx and oropharynx (OP) cancer patients...
  82. ncbi request reprint Established and emerging uses of cytoprotection in head and neck cancer
    David I Rosenthal
    Arch Otolaryngol Head Neck Surg 132:129-30. 2006
  83. ncbi request reprint Reinterpretation of cross-sectional images in patients with head and neck cancer in the setting of a multidisciplinary cancer center
    Laurie A Loevner
    Department of Radiology, University of Pennsylvania School of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    AJNR Am J Neuroradiol 23:1622-6. 2002
    ..We assessed the clinical value of reinterpreting cross-sectional imaging studies of patients with head and neck cancer, in the setting of a multidisciplinary cancer center...
  84. ncbi request reprint Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation
    Sunil Singhal
    Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Pennsylvania, Philadelphia, USA
    Ann Thorac Surg 76:1635-41; discussion 1641-2. 2003
    ..Studies addressing this issue generally report few patients and lump all patients beyond stage I together in the analysis...
  85. ncbi request reprint A multinational, randomized phase III trial of iseganan HCl oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy
    Andy Trotti
    Radiation Oncology Program, H Lee Moffitt Cancer Center at the University of South Florida, Tampa, FL, USA
    Int J Radiat Oncol Biol Phys 58:674-81. 2004
    ..It is hypothesized that infection plays a role in the development of OM. We tested the efficacy of iseganan HCl (iseganan), a synthetic peptide with broad-spectrum antimicrobial activity, for preventing RT-associated OM...
  86. ncbi request reprint Increasing toxicity in nonoperative head and neck cancer treatment: investigations and interventions
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:S79-82. 2007
  87. ncbi request reprint Sarcomatoid carcinoma of the head and neck: molecular evidence for evolution and progression from conventional squamous cell carcinomas
    Hong Ran Choi
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Am J Surg Pathol 27:1216-20. 2003
    ..Our study supports: 1) an evolution of sarcomatoid carcinoma from the conventional epithelial-type, 2) a malignant nature of the sarcomatoid component, and 3) that molecular progression is associated with the sarcomatoid transformation...
  88. ncbi request reprint Pre-analytic saliva processing affect proteomic results and biomarker screening of head and neck squamous carcinoma
    Kazufumi Ohshiro
    Department of Pathology, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Oncol 30:743-9. 2007
    ....