Cory D Rillahan

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. pmc Glycan microarrays for decoding the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA
    Annu Rev Biochem 80:797-823. 2011
  2. pmc On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7
    Cory D Rillahan
    Departments of Cell and Molecular Biology, Chemical Physiology, and Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
    ACS Chem Biol 8:1417-22. 2013
  3. pmc Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA
    Nat Chem Biol 8:661-8. 2012
  4. pmc Click and pick: identification of sialoside analogues for siglec-based cell targeting
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 51:11014-8. 2012
  5. pmc High-throughput screening for inhibitors of sialyl- and fucosyltransferases
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 50:12534-7. 2011

Detail Information

Publications5

  1. pmc Glycan microarrays for decoding the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA
    Annu Rev Biochem 80:797-823. 2011
    ..This review covers the development of glycan microarrays and applications that have provided insights into the roles of mammalian and microbial GBPs...
  2. pmc On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7
    Cory D Rillahan
    Departments of Cell and Molecular Biology, Chemical Physiology, and Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
    ACS Chem Biol 8:1417-22. 2013
    ..In silico docking to the crystal structure of Siglec-7 provides a rationale for the affinity gains observed for this novel sialic acid analogue. ..
  3. pmc Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA
    Nat Chem Biol 8:661-8. 2012
    ..As an example of the functional consequences, the inhibitors substantially reduce expression of the sialylated and fucosylated ligand sialyl Lewis X on myeloid cells, resulting in loss of selectin binding and impaired leukocyte rolling...
  4. pmc Click and pick: identification of sialoside analogues for siglec-based cell targeting
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 51:11014-8. 2012
    ..Microarray printing of the library and screening with the siglec family of sialic-acid-binding proteins, led to the identification of high-affinity ligands for siglec-9 and siglec-10...
  5. pmc High-throughput screening for inhibitors of sialyl- and fucosyltransferases
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 50:12534-7. 2011
    ..The screening of 16,000 compounds against different glycosyltransferases has identified various interesting inhibitors...