Cory D Rillahan

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. pmc Glycan microarrays for decoding the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA
    Annu Rev Biochem 80:797-823. 2011
  2. pmc On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7
    Cory D Rillahan
    Departments of Cell and Molecular Biology, Chemical Physiology, and Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
    ACS Chem Biol 8:1417-22. 2013
  3. pmc Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA
    Nat Chem Biol 8:661-8. 2012
  4. pmc Click and pick: identification of sialoside analogues for siglec-based cell targeting
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 51:11014-8. 2012
  5. pmc Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
    Norihito Kawasaki
    Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037 Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037 Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037
    J Immunol 193:1560-6. 2014
  6. pmc High-throughput screening for inhibitors of sialyl- and fucosyltransferases
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 50:12534-7. 2011

Collaborators

Detail Information

Publications6

  1. pmc Glycan microarrays for decoding the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA
    Annu Rev Biochem 80:797-823. 2011
    ..This review covers the development of glycan microarrays and applications that have provided insights into the roles of mammalian and microbial GBPs...
  2. pmc On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7
    Cory D Rillahan
    Departments of Cell and Molecular Biology, Chemical Physiology, and Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
    ACS Chem Biol 8:1417-22. 2013
    ..In silico docking to the crystal structure of Siglec-7 provides a rationale for the affinity gains observed for this novel sialic acid analogue. ..
  3. pmc Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA
    Nat Chem Biol 8:661-8. 2012
    ..As an example of the functional consequences, the inhibitors substantially reduce expression of the sialylated and fucosylated ligand sialyl Lewis X on myeloid cells, resulting in loss of selectin binding and impaired leukocyte rolling...
  4. pmc Click and pick: identification of sialoside analogues for siglec-based cell targeting
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 51:11014-8. 2012
    ..Microarray printing of the library and screening with the siglec family of sialic-acid-binding proteins, led to the identification of high-affinity ligands for siglec-9 and siglec-10...
  5. pmc Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation
    Norihito Kawasaki
    Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037 Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037 Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037
    J Immunol 193:1560-6. 2014
    ..These data suggest that the endocytic function of Siglec-7 can be exploited to deliver glycolipid Ags to their target cell and increase the efficiency of display to T cells. ..
  6. pmc High-throughput screening for inhibitors of sialyl- and fucosyltransferases
    Cory D Rillahan
    Department of Chemical Physiology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    Angew Chem Int Ed Engl 50:12534-7. 2011
    ..The screening of 16,000 compounds against different glycosyltransferases has identified various interesting inhibitors...