Laura G Reinholdt

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. pmc Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries
    Anuj Srivastava
    Computational Sciences, The Jackson Laboratory, Bar Harbor, ME USA
    BMC Genomics 15:367. 2014
  2. pmc Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
    Laura G Reinholdt
    The Jackson Laboratory, Genetic Resource Science, ME, 04609, USA
    Mamm Genome 22:685-91. 2011
  3. pmc Derivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains
    Anne Czechanski
    Genetic Resource Science, The Jackson Laboratory, Bar Harbor, Maine, USA
    Nat Protoc 9:559-74. 2014
  4. pmc Mutation discovery in mice by whole exome sequencing
    Heather Fairfield
    The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA
    Genome Biol 12:R86. 2011
  5. pmc Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome
    Laura G Reinholdt
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Chromosoma 118:723-36. 2009
  6. pmc BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat
    Wesley G Beamer
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    J Bone Miner Res 26:88-99. 2011

Collaborators

Detail Information

Publications6

  1. pmc Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries
    Anuj Srivastava
    Computational Sciences, The Jackson Laboratory, Bar Harbor, ME USA
    BMC Genomics 15:367. 2014
    ..Nearly 6,500 transgenic alleles have been created by random integration in embryos over the last 30 years, but for the vast majority of these strains, the transgene insertion sites remain uncharacterized...
  2. pmc Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
    Laura G Reinholdt
    The Jackson Laboratory, Genetic Resource Science, ME, 04609, USA
    Mamm Genome 22:685-91. 2011
    ..These data provide the basis for low-cost, highly efficient genotyping of Ts65Dn mice. More importantly, these data provide, for the first time, complete characterization of gene dosage in Ts65Dn mice...
  3. pmc Derivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains
    Anne Czechanski
    Genetic Resource Science, The Jackson Laboratory, Bar Harbor, Maine, USA
    Nat Protoc 9:559-74. 2014
    ..By using this protocol, mESCs can be derived in 3 weeks and fully characterized after an additional 12 weeks, at efficiencies as high as 90% and in any strain background. ..
  4. pmc Mutation discovery in mice by whole exome sequencing
    Heather Fairfield
    The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA
    Genome Biol 12:R86. 2011
    ..We found strong candidate mutations for the majority of mutant exomes sequenced, including new models of orofacial clefting, urogenital dysmorphology, kyphosis and autoimmune hepatitis...
  5. pmc Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome
    Laura G Reinholdt
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Chromosoma 118:723-36. 2009
    ..These results reveal mechanisms by which an extra chromosome, but not trisomic gene dose, impact on meiotic progress and infertility...
  6. pmc BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat
    Wesley G Beamer
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    J Bone Miner Res 26:88-99. 2011
    ..In conclusion, our data suggest that osteoblasts are the cellular target of gene action and that AC084073.22 is the best candidate for female BMD regulation in the distal region of mouse Chr 1...