Research Topics
Genomes and GenesSpecies | Laura G ReinholdtSummaryAffiliation: The Jackson Laboratory Country: USA Publications
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Detail Information
Publications
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65DnLaura G Reinholdt
The Jackson Laboratory, Genetic Resource Science, ME, 04609, USA
Mamm Genome 22:685-91. 2011..These data provide the basis for low-cost, highly efficient genotyping of Ts65Dn mice. More importantly, these data provide, for the first time, complete characterization of gene dosage in Ts65Dn mice...
Mutation discovery in mice by whole exome sequencingHeather Fairfield
The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA
Genome Biol 12:R86. 2011..We found strong candidate mutations for the majority of mutant exomes sequenced, including new models of orofacial clefting, urogenital dysmorphology, kyphosis and autoimmune hepatitis...
Meiotic behavior of aneuploid chromatin in mouse models of Down syndromeLaura G Reinholdt
The Jackson Laboratory, Bar Harbor, ME 04609, USA
Chromosoma 118:723-36. 2009..These results reveal mechanisms by which an extra chromosome, but not trisomic gene dose, impact on meiotic progress and infertility...
BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fatWesley G Beamer
The Jackson Laboratory, Bar Harbor, ME 04609, USA
J Bone Miner Res 26:88-99. 2011..In conclusion, our data suggest that osteoblasts are the cellular target of gene action and that AC084073.22 is the best candidate for female BMD regulation in the distal region of mouse Chr 1...
