Research Topics
| Leslie RaffiniSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
| Collaborators
|
Detail Information
Publications
Subgaleal hematoma from hair braiding leads to the diagnosis of von Willebrand diseaseLeslie Raffini
Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Emerg Care 20:316-8. 2004..To our knowledge, this is the first case of von Willebrand disease presenting as a subgaleal hematoma. von Willebrand disease is a common inherited bleeding disorder which should be considered in patients with unusual bleeding...
Dramatic increase in venous thromboembolism in children's hospitals in the United States from 2001 to 2007Leslie Raffini
Division of Hematology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, USA
Pediatrics 124:1001-8. 2009....- Testing children for inherited thrombophilia: more questions than answersLeslie Raffini
Division of Hematology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
Br J Haematol 147:277-88. 2009..Future studies, many of which are currently being performed or proposed, are necessary to address many of the unanswered questions... - Thromboelastography of patients after fontan compared with healthy childrenLeslie Raffini
Division of Hematology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
Pediatr Cardiol 30:771-6. 2009..Further studies comparing the thromboelastography of Fontan patients with the thromboembolic complications of those without Fontan are needed to delineate these issues... - Thrombolysis for intravascular thrombosis in neonates and childrenLeslie Raffini
Division of Hematology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
Curr Opin Pediatr 21:9-14. 2009..This article reviews the fibrinolytic pathway and discusses the current agents available for thrombolytic therapy, as well as indications for their use, dosing regimens, safety, and efficacy... - A prospective observational study of IVC filters in pediatric patientsLeslie Raffini
Division of Hematology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Pediatr Blood Cancer 51:517-20. 2008..Both permanent and retrievable filters have been used in the pediatric population, though reports describing such patients and their outcomes are limited... - Cystic fibrosis as a risk factor for recurrent venous thrombosis at a pediatric tertiary care hospitalLeslie J Raffini
Division of Hematology, The Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia 19104 4399, USA
J Pediatr 148:659-64. 2006..To evaluate risk factors for recurrent thrombosis in pediatric patients... - May-Thurner syndrome (iliac vein compression) and thrombosis in adolescentsLeslie Raffini
Department of Pediatrics, Division of Hematology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
Pediatr Blood Cancer 47:834-8. 2006..Though uncommon, pediatric hematologists should consider May-Thurner syndrome in adolescents who present with a left lower extremity thrombosis. Aggressive therapy may be warranted due to the risk of post-thrombotic syndrome... - Prolongation of the prothrombin time and activated partial thromboplastin time in children with sickle cell diseaseLeslie J Raffini
Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, and Duke University School of Medicine, Durham, NC, USA
Pediatr Blood Cancer 47:589-93. 2006..Patients with sickle cell disease (SCD) have high rates of perioperative complications, including bleeding 1,2... - Evaluation of pulmonary embolism in a pediatric population with high clinical suspicionTeresa Victoria
Department of Radiology, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19103, USA
Pediatr Radiol 39:35-41. 2009..Pulmonary embolism (PE) is an underdiagnosed entity in the pediatric population in part because of the low level of suspicion and awareness in the clinical world... - The clinical management of hemophilia and head trauma: a survey of current clinical practice among pediatric hematology/oncology physiciansChar M Witmer
Division of Hematology, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Pediatr Blood Cancer 53:406-10. 2009..Determining the appropriate evaluation for a pediatric patient with hemophilia and head trauma is a diagnostic challenge with no neuroimaging guidelines and limited clinical evidence to direct care... - Mycoplasma pneumoniae, splenic infarct, and transient antiphospholipid antibodies: a new association?Char M Witmer
Division of Hematology, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 119:e292-5. 2007..We report 2 children with Mycoplasma pneumoniae pulmonary infection with splenic infarcts and transient antiphospholipid antibodies. This association has not been reported previously... - Incidence of bleeding complications in pediatric patients with type 1 von Willebrand disease undergoing adenotonsillar proceduresChar M Witmer
Department of Pediatrics, Division of Hematology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Pediatr 155:68-72. 2009..To review the incidence of postoperative bleeding in children with type 1 von Willebrand disease (VWD) who were treated with a single institution protocol... - Thromboprophylaxis in a pediatric hospital: a patient-safety and quality-improvement initiativeLeslie Raffini
Division of Hematology, Children s Hospital of Philadelphia, 11022 CTRB, 3501 Civic Center Blvd, Philadelphia, PA 19104, USA
Pediatrics 127:e1326-32. 2011..The objectives of this study were to review our current hospital practice, identify a population at high risk, and formulate institutional guidelines for thromboprophylaxis... - Associations between intracranial haemorrhage and prescribed prophylaxis in a large cohort of haemophilia patients in the United StatesChar Witmer
Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA
Br J Haematol 152:211-6. 2011..This is the first study to demonstrate that prescribed prophylaxis conferred a protective effect against ICH in patients with uncomplicated severe disease... - Widespread use of fresh frozen plasma in US children's hospitals despite limited evidence demonstrating a beneficial effectJohn Puetz
Department of Pediatrics, Division of Hematology Oncology, Saint Louis University, Cardinal Glennon Children s Medical Center, St Louis, MO 63104, USA
J Pediatr 160:210-215.e1. 2012..To determine the pattern, prevalence and potential complications of fresh frozen plasma (FFP) use in US pediatric hospitals from 2002-2009... 
Headache in children with sickle cell disease: prevalence and associated factorsAlison E Niebanck
Duke University School of Medicine, USA
J Pediatr 151:67-72, 72.e1. 2007..To compare the prevalence of frequent headache in children with sickle cell disease (SCD) to that of black control subjects and to assess factors associated with headache in SCD...