Jason J Radley

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cereb Cortex 16:313-20. 2006
  2. pmc Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 28:5806-16. 2008
  3. pmc Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex
    Jason J Radley
    Laboratory of Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Comp Neurol 507:1141-50. 2008
  4. pmc Distribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Brain Res 1134:87-94. 2007
  5. ncbi request reprint Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, and Foundation for Medical Research, La Jolla, California 92037, USA
    J Neurosci 26:12967-76. 2006
  6. ncbi request reprint Associative Pavlovian conditioning leads to an increase in spinophilin-immunoreactive dendritic spines in the lateral amygdala
    Jason J Radley
    Laboratory for Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Eur J Neurosci 24:876-84. 2006
  7. ncbi request reprint Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Exp Neurol 196:199-203. 2005
  8. pmc A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 29:7330-40. 2009
  9. ncbi request reprint Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    Conor Liston
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 26:7870-4. 2006
  10. ncbi request reprint Repeated stress and structural plasticity in the brain
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Ageing Res Rev 4:271-87. 2005

Detail Information

Publications10

  1. ncbi request reprint Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cereb Cortex 16:313-20. 2006
    ..Dendritic atrophy and spine loss may be important cellular features of stress-related psychiatric disorders where the PFC is functionally impaired...
  2. pmc Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 28:5806-16. 2008
    ..These findings identify the LC as an upstream component of a circuitry providing for dorsal mPFC modulation of emotional stress-induced HPA activation...
  3. pmc Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex
    Jason J Radley
    Laboratory of Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Comp Neurol 507:1141-50. 2008
    ..These results suggest a failure of spines to mature and stabilize following repeated stress and are likely to have major repercussions on function, receptor expression, and synaptic efficacy...
  4. pmc Distribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Brain Res 1134:87-94. 2007
    ....
  5. ncbi request reprint Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, and Foundation for Medical Research, La Jolla, California 92037, USA
    J Neurosci 26:12967-76. 2006
    ..These results suggest that dorsal and ventral aspects of the mPFC differentially regulate neuroendocrine and autonomic PVH outputs in response to emotional stress...
  6. ncbi request reprint Associative Pavlovian conditioning leads to an increase in spinophilin-immunoreactive dendritic spines in the lateral amygdala
    Jason J Radley
    Laboratory for Neuronal Structure and Function, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Eur J Neurosci 24:876-84. 2006
    ....
  7. ncbi request reprint Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    Jason J Radley
    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Exp Neurol 196:199-203. 2005
    ..These results suggest that stress-induced dendritic plasticity in the medial PFC is reversible and may have implications for the functional recovery of medial PFC function following prolonged psychological stress...
  8. pmc A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and Clayton Medical Research Foundation, La Jolla, California 92037, USA
    J Neurosci 29:7330-40. 2009
    ....
  9. ncbi request reprint Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    Conor Liston
    Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 26:7870-4. 2006
    ..This study provides the first direct evidence that dendritic remodeling in the prefrontal cortex may underlie the functional deficits in attentional control that are symptomatic of stress-related mental illnesses...
  10. ncbi request reprint Repeated stress and structural plasticity in the brain
    Jason J Radley
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Ageing Res Rev 4:271-87. 2005
    ..How functional impairments in these brain regions play a role in stress-related mental illnesses is discussed in this context. Finally, we discuss the cumulative impact of stress-induced structural plasticity in aging...