Victor G Prieto

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Cutaneous melanocytic lesions: do not miss the invisible gorilla
    Victor G Prieto
    Department of Pathology and Dermatology, MD Anderson Cancer Center, University of Texas, Houston, 77030, USA
    Adv Anat Pathol 19:263-9. 2012
  2. pmc Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma
    Antoni Ribas
    University of California Los Angeles UCLA, CA, USA
    J Transl Med 8:89. 2010
  3. doi request reprint Use of immunohistochemistry in melanocytic lesions
    Victor G Prieto
    Department of Pathology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 35:1-10. 2008
  4. doi request reprint Sentinel lymph nodes in cutaneous melanoma: handling, examination, and clinical repercussion
    Victor G Prieto
    Departments of Pathology and Dermatology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Arch Pathol Lab Med 134:1764-9. 2010
  5. doi request reprint Immunohistochemistry of melanocytic proliferations
    Victor G Prieto
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Arch Pathol Lab Med 135:853-9. 2011
  6. doi request reprint Sentinel lymph nodes in cutaneous melanoma
    Victor G Prieto
    Department of Pathology, University of Texas, MD Anderson Cancer Center, Houston, 77030, USA
    Clin Lab Med 31:301-10. 2011
  7. ncbi request reprint Use of frozen sections in the examination of sentinel lymph nodes in patients with melanoma
    Victor G Prieto
    Department of Pathology, University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Semin Diagn Pathol 25:112-5. 2008
  8. ncbi request reprint Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma
    Victor G Prieto
    Department of Pathology, The University of Texas M D Anderson Cancer Center, The Methodist Hospital, Houston 77030, USA
    Clin Cancer Res 12:6709-15. 2006
  9. pmc Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 122:2077-84. 2008
  10. ncbi request reprint Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Invest Dermatol 127:276-80. 2007

Detail Information

Publications113 found, 100 shown here

  1. doi request reprint Cutaneous melanocytic lesions: do not miss the invisible gorilla
    Victor G Prieto
    Department of Pathology and Dermatology, MD Anderson Cancer Center, University of Texas, Houston, 77030, USA
    Adv Anat Pathol 19:263-9. 2012
    ..Regarding this apparently bizarre choice to illustrate these problems (to not miss an invisible gorilla), we request the reader to continue reading this article to find out why...
  2. pmc Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma
    Antoni Ribas
    University of California Los Angeles UCLA, CA, USA
    J Transl Med 8:89. 2010
    ....
  3. doi request reprint Use of immunohistochemistry in melanocytic lesions
    Victor G Prieto
    Department of Pathology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 35:1-10. 2008
    ..Following Dr McNutt's lead, in this article, we describe the use of immunohistochemistry as a diagnostic aid in dermatopathology as well as the potential pitfalls commonly encountered in practice...
  4. doi request reprint Sentinel lymph nodes in cutaneous melanoma: handling, examination, and clinical repercussion
    Victor G Prieto
    Departments of Pathology and Dermatology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Arch Pathol Lab Med 134:1764-9. 2010
    ..Approximately 20% of patients with cutaneous melanoma have metastasis in the SLN. In most studies, detection of positive SLN conveys a poorer prognosis for patients with cutaneous melanoma...
  5. doi request reprint Immunohistochemistry of melanocytic proliferations
    Victor G Prieto
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Arch Pathol Lab Med 135:853-9. 2011
    ..Only in a minority of lesions is it necessary to use other techniques as an aid in the diagnosis. Among them, most authors recommend immunohistochemistry...
  6. doi request reprint Sentinel lymph nodes in cutaneous melanoma
    Victor G Prieto
    Department of Pathology, University of Texas, MD Anderson Cancer Center, Houston, 77030, USA
    Clin Lab Med 31:301-10. 2011
    ..Current studies are evaluating the possible therapeutic value of removal of positive SLN, but it is accepted by most authors that detection of positive SLN conveys an impaired prognosis for patients who have cutaneous melanoma...
  7. ncbi request reprint Use of frozen sections in the examination of sentinel lymph nodes in patients with melanoma
    Victor G Prieto
    Department of Pathology, University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Semin Diagn Pathol 25:112-5. 2008
    ..This article examines the different views regarding the use of frozen sections and other rapid techniques in sentinel lymph nodes from patients with cutaneous melanoma. Special attention is given to the pros and cons of such techniques...
  8. ncbi request reprint Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma
    Victor G Prieto
    Department of Pathology, The University of Texas M D Anderson Cancer Center, The Methodist Hospital, Houston 77030, USA
    Clin Cancer Res 12:6709-15. 2006
    ....
  9. pmc Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 122:2077-84. 2008
    ..013) in modifying risk. Together, these findings suggest that VDR polymorphisms may directly affect or modify the risk associated with known melanoma risk factors. Larger, population-based studies are needed to replicate our findings...
  10. ncbi request reprint Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Invest Dermatol 127:276-80. 2007
    ..26; 95% CI, 1.00-1.59) genotypes, compared with the VDR-FokI FF genotype. In conclusion, genetic variants (i.e., TaqI t protective allele and FokI f risk allele) in VDR may alter risk of CM...
  11. doi request reprint Immunodetection of phosphohistone H3 as a surrogate of mitotic figure count and clinical outcome in cutaneous melanoma
    Michael T Tetzlaff
    Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77005, USA
    Mod Pathol 26:1153-60. 2013
    ....
  12. ncbi request reprint Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Unit 1365, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 15:2526-32. 2006
    ..We concluded that genetic variants of the XPD gene might serve as biomarkers for susceptibility to cutaneous melanoma...
  13. ncbi request reprint Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 109:1570-8. 2007
    ..The authors hypothesized that selected functional single-nucleotide polymorphisms (SNPs) in the nNOS and iNOS genes are associated with the risk of CM...
  14. ncbi request reprint Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression
    Carmen S Tellez
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Invest Dermatol 127:387-93. 2007
    ..These findings support our hypothesis that loss of AP-2 is a crucial event in the progression of human melanoma and contributes to the acquisition of the metastatic phenotype via upregulation of PAR-1...
  15. pmc Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma
    Chunying Li
    Department of Epidemiology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Hum Mutat 29:1443-51. 2008
    ..Therefore, these CASP8 and CASP10 polymorphisms may be biomarkers for susceptibility to CM...
  16. ncbi request reprint Repair capacity for UV light induced DNA damage associated with risk of nonmelanoma skin cancer and tumor progression
    Li E Wang
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 13:6532-9. 2007
    ..To examine the role of suboptimal DNA repair capacity (DRC) for UV light-induced DNA damage in the development of nonmelanoma skin cancer (NMSC) and tumor progression...
  17. ncbi request reprint Genetic variants of the ADPRT, XRCC1 and APE1 genes and risk of cutaneous melanoma
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Carcinogenesis 27:1894-901. 2006
    ..Larger studies with more SNPs in the BER genes are needed to verify these findings...
  18. doi request reprint A randomized phase III trial of biochemotherapy versus interferon-alpha-2b for adjuvant therapy in patients at high risk for melanoma recurrence
    Kevin B Kim
    Department of Melanoma Medical Oncology, M D Anderson Cancer Center, The University of Texas, Houston 77030, Texas, USA
    Melanoma Res 19:42-9. 2009
    ..86 and 0.45, respectively) between the two groups. Biochemotherapy is not more effective than IFN as adjuvant therapy for melanoma. These findings support early termination of this trial...
  19. doi request reprint Sentinel lymph node biopsy for ocular adnexal melanoma: experience in 30 patients
    Aaron Savar
    Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthalmology 116:2217-23. 2009
    ..To report the findings on sentinel lymph node biopsy (SLNB) in 30 patients with ocular adnexal (conjunctival or eyelid) melanomas...
  20. doi request reprint COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin
    Wei Lien Wang
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
    Am J Dermatopathol 32:149-53. 2010
    ..Although indeterminate fibrohistiocytic lesions share some features with DFSP, the lack of COL1A1-PDGFB chimeric transcripts suggests that they are distinct entities...
  21. pmc Microscopic tumor burden in sentinel lymph nodes predicts synchronous nonsentinel lymph node involvement in patients with melanoma
    Jeffrey E Gershenwald
    Department of Surgical Oncology, Division of Quantitative Sciences, Unit 444, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 26:4296-303. 2008
    ..We sought to determine predictors of additional regional LN involvement in patients with positive SLNs...
  22. doi request reprint Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma
    Michael A Davies
    Departments of Melanoma Medical Oncology, Systems Biology, Biostatistics, Pathology, Experimental Therapeutics, and Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Clin Cancer Res 18:1120-8. 2012
    ..Tumor biopsies were analyzed for activating mutations in BRAF and NRAS, and for expression of P-extracellular signal-regulated kinase (P-ERK) and P-S6 proteins...
  23. pmc Influence of single nucleotide polymorphisms in the MMP1 promoter region on cutaneous melanoma progression
    Hongliang Liu
    Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Melanoma Res 22:169-75. 2012
    ....
  24. ncbi request reprint Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma
    Chunying Li
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Pharmacogenet Genomics 16:253-63. 2006
    ..In conclusion, genetic variants in the FAS and FASLG genes may contribute to the etiology of CMM in the general population, particularly in those with a low risk of sunlight-induced CMM...
  25. ncbi request reprint Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms
    Michael L Cohn
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 32:533-6. 2005
    ..Cohn ML, Goncharuk VN, Diwan AH, Zhang PS, Shen SS, Prieto VG. Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms...
  26. ncbi request reprint Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells
    Suhendan Ekmekcioglu
    Department of Bioimmunotherapy, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Cancer Ther 2:9-17. 2003
    ..These studies demonstrate that expression of the MDA-7 tumor suppressor can negatively regulate iNOS expression in malignant melanoma cell lines...
  27. ncbi request reprint Assessment of the role of sentinel lymph node biopsy for primary cutaneous desmoplastic melanoma
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77230, USA
    Cancer 106:900-6. 2006
    ..The role of sentinel lymph node biopsy (SLNB) in the treatment of desmoplastic melanoma (DM) remains undefined. The purpose of this study was to evaluate the use of SLNB for DM...
  28. ncbi request reprint Accuracy of lymphatic mapping and sentinel lymph node biopsy after previous wide local excision in patients with primary melanoma
    Christopher J Gannon
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Cancer 107:2647-52. 2006
    ..The purpose of this study was to assess the feasibility and accuracy of LM/SLNB in patients who have had a previous WLE...
  29. ncbi request reprint Tumor iNOS predicts poor survival for stage III melanoma patients
    Suhendan Ekmekcioglu
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 119:861-6. 2006
    ..The ability of iNOS to predict outcomes for these patients may be independent of other known prognostic factors, providing a new molecular marker with significant potential for clinical utility...
  30. ncbi request reprint Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma
    Matthew T Ballo
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    J Clin Oncol 20:4555-8. 2002
    ..To evaluate the outcome and toxicity of a sphincter-sparing treatment strategy in the management of patients with anal-rectal melanoma...
  31. ncbi request reprint Revised American Joint Committee on Cancer staging criteria accurately predict sentinel lymph node positivity in clinically node-negative melanoma patients
    Dennis L Rousseau
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Ann Surg Oncol 10:569-74. 2003
    ..The purpose of this study was to correlate the incidence of SLN metastasis with revised AJCC staging...
  32. ncbi request reprint Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin
    Doina Ivan
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Cutan Pathol 34:474-80. 2007
    ..Metastases from adnexal carcinomas generally retain p63 expression similar to their associated primary tumors...
  33. pmc Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment
    Cindy S Hwang
    School of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Melanoma Res 18:241-5. 2008
    ..A better understanding of the AKT and mitogen-activated protein kinase pathways is needed to optimize the clinical benefit of targeted therapy, such as imatinib...
  34. doi request reprint Changes in tumor morphology and cyclin-dependent kinase inhibitor expression in metastatic melanoma treated with selective second-generation BRAF inhibitor
    Jonathan L Curry
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Dermatopathol 35:125-8. 2013
    ..Furthermore, awareness of changes in tumor morphology after treatment with RAF inhibitors may be helpful in histologic evaluation of the spectrum of dermatologic toxicity, which may occur on targeted therapy...
  35. doi request reprint Cutaneous adnexal tumor with an unusual presentation--discussion of a potential diagnostic pitfall
    John J Cangelosi
    Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Am J Dermatopathol 31:278-81. 2009
    ..This discrimination is of a paramount importance because a diagnostic error can result in profound implications for patient's assumed prognosis and subsequently applied therapy...
  36. doi request reprint Expression of Sox-9 in metastatic melanoma--a potential diagnostic pitfall
    Priya Rao
    Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Dermatopathol 32:262-6. 2010
    ..Last, our data confirm that SOX-9 is not a specific marker for tumors of cartilage lineage and may be expressed in other tumors of neural crest origin...
  37. pmc Clinical correlates of NRAS and BRAF mutations in primary human melanoma
    Julie A Ellerhorst
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:229-35. 2011
    ..This study was designed to test the hypothesis that primary human cutaneous melanomas harboring mutations in NRAS or BRAF display a more aggressive clinical phenotype than tumors wild type at both loci...
  38. ncbi request reprint Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type
    Carlos A Torres-Cabala
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Mod Pathol 22:1446-56. 2009
    ....
  39. ncbi request reprint Implications of lymphatic drainage to unusual sentinel lymph node sites in patients with primary cutaneous melanoma
    William E Sumner
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:354-60. 2002
    ..The objective of this study was to determine the frequency and significance of unusual sentinel lymph node drainage patterns in a large cohort of patients with primary melanoma...
  40. ncbi request reprint High flotillin-2 expression is associated with lymph node metastasis and Breslow depth in melanoma
    Sean D Doherty
    Baylor College of Medicine, Houston, Texas, USA
    Melanoma Res 16:461-3. 2006
  41. ncbi request reprint Analysis of protein tyrosine kinases expression in the melanoma metastases of patients treated with Imatinib Mesylate (STI571, Gleevec)
    Doina Ivan
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Cutan Pathol 33:280-5. 2006
    ..Gleevec, a novel class of anti-tumor drugs, may have a potential therapeutic benefit in melanoma, which involves abnormal activation of abl, c-kit, and platelet-derived growth factor (PDGF) tyrosine kinases...
  42. doi request reprint Positive sentinel node in sebaceous carcinoma of the eyelid
    Aaron Savar
    Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthal Plast Reconstr Surg 27:e4-6. 2011
    ....
  43. doi request reprint Cutaneous melanoma metastatic to the eyelid and periocular skin
    Ruben Ramirez
    Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthal Plast Reconstr Surg 26:88-94. 2010
    ..To report the clinical and histopathologic features in 6 patients with cutaneous melanoma metastatic to the eyelid and periocular skin...
  44. ncbi request reprint Expression of thyrotropin-releasing hormone by human melanoma and nevi
    Julie A Ellerhorst
    Department of Bioimmunotherapy, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 10:5531-6. 2004
    ..RNA transcripts for the TRH prohormone have recently been described in melanoma cell lines. To expand these findings, we have examined cultured melanoma cells and melanocytes, human melanoma tumors, and nevi for the expression of TRH...
  45. doi request reprint Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity
    A Hafeez Diwan
    Department of Pathology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 35:647-50. 2008
    ..Twenty-three of 29 DFSP (79%) and 2 of 5 GCP (40%) expressed CD99. Comparison of CD99 and CD34 showed that the non-tumoral periphery of DFSP was less probable to be CD99 positive, but this finding was not statistically significant...
  46. doi request reprint Clusterin expression correlates with stage and presence of large cells in mycosis fungoides
    Pranil Chandra
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 85, Houston, TX 77030, USA
    Am J Clin Pathol 131:511-5. 2009
    ..Clusterin expression was not specific for MF as it also was positive in 3 of 3 cases of LyP, 2 of 2 systemic ALCL cases involving skin, 7 of 16 cutaneous ALCLs, and 1 of 6 PTCLs...
  47. pmc Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma
    Li E Wang
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Eur J Cancer 47:107-15. 2011
    ..56 and 2.13, 95% CIs=1.02-2.38 and 1.22-3.70, respectively). These findings suggest that MMP1 promoter polymorphisms may individually or jointly play roles in the development of CM...
  48. doi request reprint Ambiguous melanocytic tumors in a tertiary referral center: the contribution of fluorescence in situ hybridization (FISH) to conventional histopathologic and immunophenotypic analyses
    Michael T Tetzlaff
    Department of Pathology, Section of Dermatopathology Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
    Am J Surg Pathol 37:1783-96. 2013
    ..In contrast, a positive FISH test should be carefully interrogated in the context of the complete histopathologic findings. ..
  49. doi request reprint Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib
    Zita Dubauskas
    Department of Genitourinary Medical Oncology, The University of Texas Health Science Center, Houston, TX 77030, USA
    Clin Genitourin Cancer 7:20-3. 2009
    ..Cutaneous squamous cell carcinoma (SCC) and inflammation of actinic keratosis (AK) were reported in 2 patients treated with sorafenib (Lacouture et al), but the scope of this observation has not been evaluated...
  50. ncbi request reprint Merkel cell polyomavirus and HPV-17 associated with cutaneous squamous cell carcinoma arising in a patient with melanoma treated with the BRAF inhibitor dabrafenib
    Gerald S Falchook
    Division of Cancer Medicine, Departmentof Investigational Cancer Therapeutics, Phase I Clinical Trials Program, MD Anderson Cancer Center, Houston, TX 77030, USA
    JAMA Dermatol 149:322-6. 2013
    ..We report what we believe to be the first case in which Merkel cell polyomavirus (MCPyV) and human papillomavirus subtype 17 (HPV-17) were associated with cutaneous SCC that developed during treatment with the BRAF inhibitor dabrafenib...
  51. doi request reprint Differential expression of the G-protein-coupled formyl Peptide receptor in melanoma associates with aggressive phenotype
    Nitin Chakravarti
    Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Dermatopathol 35:184-90. 2013
    ..0089). Our findings reveal that FPR and FPRL1 are overexpressed in primary melanoma and correlate with aggressive tumor characteristics, underscoring them as potential therapeutic targets...
  52. doi request reprint Molecular platforms utilized to detect BRAF V600E mutation in melanoma
    Jonathan L Curry
    Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Semin Cutan Med Surg 31:267-73. 2012
    ....
  53. pmc Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells
    Hong Mu
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Pathol 180:2170-81. 2012
    ....
  54. doi request reprint Dermatofibrosarcoma protuberans with unusual sarcomatous transformation: a series of 4 cases with molecular confirmation
    Michael G Swaby
    Department of Pathology, The University of Texas Medical School, Houston, TX, USA
    Am J Dermatopathol 33:354-60. 2011
    ..Ancillary diagnostic testing may be helpful to confirm the diagnosis, especially in small biopsies...
  55. ncbi request reprint Decreased expression of retinoid receptors in melanoma: entailment in tumorigenesis and prognosis
    Nitin Chakravarti
    Department of Head and Neck Thoracic Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 13:4817-24. 2007
    ..We have studied the in situ expression of each RAR and RXR protein (alpha, beta, gamma) in a large series of melanocytic lesions and correlated the expression with clinicopathologic features and prognosis of the patients...
  56. ncbi request reprint A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors
    Lei L Chen
    Department of Sarcoma, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA llchen mdanderson org
    Cancer Res 64:5913-9. 2004
    ..Allelic-specific sequencing data show that this new mutation occurs in the allele that harbors original activation mutation of KIT...
  57. ncbi request reprint Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib
    David S Hong
    Phase I Program, Department of Investigational Cancer Therapeutics, Unit 455, Division of Cancer Medicine, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Arch Dermatol 144:779-82. 2008
    ....
  58. ncbi request reprint Expression of the epidermal growth factor receptor in conjunctival squamous cell carcinoma
    Todd R Shepler
    Section of Ophthalmology, Department of Plastic Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Ophthal Plast Reconstr Surg 22:113-5. 2006
    ..To determine whether the tyrosine kinase epidermal growth factor receptor (EGFR) is expressed in squamous cell carcinoma of the conjunctiva...
  59. doi request reprint Atypical histologic and immunohistochemical findings in melanocytic nevi after liquid nitrogen cryotherapy
    Adebowale J Adeniran
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Am Acad Dermatol 61:341-5. 2009
    ..Histologically, there was loss of maturation and aberrant HMB-45 expression. These features may pose a diagnostic dilemma, and highlight the importance of clinicopathologic correlation in arriving at the correct diagnosis...
  60. ncbi request reprint Nuclear expression of the antiapoptotic protein survivin in malignant melanoma
    Yiling Ding
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:1123-9. 2006
    ..However, its diagnostic value in differentiating melanomas from nevi has not yet been examined...
  61. pmc A phase II study of gefitinib in patients with metastatic melanoma
    Sapna P Patel
    Department of Melanoma Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Melanoma Res 21:357-63. 2011
    ..We concluded that gefitinib was well tolerated but had minimal clinical efficacy as a single-agent therapy for unselected patients with metastatic melanoma...
  62. doi request reprint Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases
    Daniel A Ostler
    Departments of Pathology and Dermatology, Baylor College of Medicine, The University of Texas, M D Anderson Cancer Center, Houston, TX, USA
    Mod Pathol 23:567-73. 2010
    ..The pattern of adipophilin reactivity is important to observe as membranous vesicular staining is suggestive of intracellular lipids whereas granular cytoplasmic reactivity is not...
  63. doi request reprint Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma
    Doina Ivan
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Cutan Pathol 37:231-6. 2010
    ....
  64. ncbi request reprint A mutation-created novel intra-exonic pre-mRNA splice site causes constitutive activation of KIT in human gastrointestinal stromal tumors
    Lei L Chen
    Department of Sarcoma, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Oncogene 24:4271-80. 2005
    ....
  65. ncbi request reprint Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma
    David A Biddle
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Am J Surg Pathol 27:673-81. 2003
    ....
  66. ncbi request reprint Are en face frozen sections accurate for diagnosing margin status in melanocytic lesions?
    Victor G Prieto
    Dept of Pathology, Box 85, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Clin Pathol 120:203-8. 2003
    ..1282 to 0.6615). If permanent histology is considered the "gold standard" for histologic evaluation, en face frozen sections are not suitable for accurate surgical margin assessment of melanocytic lesions...
  67. ncbi request reprint HMB-45 (gp103) and MART-1 expression within giant cells in an atypical fibroxanthoma: a case report
    Megan J Smith-Zagone
    Department of Pathology, M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 31:284-6. 2004
    ..The histologic differential diagnosis primarily includes spindle cell squamous carcinoma and spindle cell melanoma, and immunohistochemical studies are often needed to establish the diagnosis...
  68. ncbi request reprint Expression of retinoid receptors in sebaceous cell carcinoma
    Nitin Chakravarti
    Department of Head and Neck Thoracic Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 33:10-7. 2006
    ....
  69. ncbi request reprint Expression of p63 in primary cutaneous adnexal neoplasms and adenocarcinoma metastatic to the skin
    Doina Ivan
    Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Mod Pathol 18:137-42. 2005
    ..001). Based on our findings, analysis of p63 expression may help in the differential diagnosis of primary vs metastatic cutaneous adenocarcinomas...
  70. ncbi request reprint Consumption of the epidermis: a criterion in the differential diagnosis of melanoma and dysplastic nevi that is associated with increasing breslow depth and ulceration
    Ruth Fulghum Walters
    Department of Pathology, University of North Carolina Hospitals, Chapel Hill, NC 27599 7287, USA
    Am J Dermatopathol 29:527-33. 2007
    ..Furthermore, the process leading to COE may be the first step in a progression to ulceration...
  71. ncbi request reprint A subgroup of melanocytic nevi on the distal lower extremity (ankle) shares features of acral nevi, dysplastic nevi, and melanoma in situ: a potential misdiagnosis of melanoma in situ
    Ibrahim Khalifeh
    M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 31:1130-6. 2007
    ..After complete excision, follow-up data indicate an apparently benign outcome. Pathologists should be aware of this type of lesions to avoid overdiagnosis of melanoma...
  72. ncbi request reprint Melanoma of the penis, scrotum and male urethra: a 40-year single institution experience
    Ricardo Sanchez-Ortiz
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    J Urol 173:1958-65. 2005
    ..We describe our experience with 10 patients with penile or urethral involvement. In addition, we present what is to our knowledge the largest reported series of melanoma of the scrotum (6 cases)...
  73. ncbi request reprint Sentinel lymph node biopsy for sebaceous cell carcinoma and melanoma of the ocular adnexa
    Viet H Ho
    Section of Ophthalmology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Arch Otolaryngol Head Neck Surg 133:820-6. 2007
    ..To provide clinical details and long-term outcome data for a series of patients with eyelid or conjunctival melanoma or eyelid sebaceous cell carcinoma who underwent sentinel lymph node (SLN) biopsy...
  74. pmc Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy
    Richard W Joseph
    Department of Melanoma Medical Oncology, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:4882-91. 2011
    ..However, little is known how clinical and pathologic features impact TIL outgrowth isolated from metastatic melanoma tumors...
  75. ncbi request reprint Phosphoinositide 3-kinase is not overexpressed in melanocytic lesions
    Rajendra S Singh
    Department of Pathology, Wayne State University, Detroit, MI, USA
    J Cutan Pathol 34:220-5. 2007
    ....
  76. ncbi request reprint Expression of dicarbonyl/L-xylulose reductase (DCXR) in human skin and melanocytic lesions: morphological studies supporting cell adhesion function of DCXR
    Jeong Hee Cho-Vega
    Department of Pathology, The Methodist Hospital, Houston, TX, USA
    J Cutan Pathol 34:535-42. 2007
    ..It has been proposed that dicarbonyl/L-xylulose reductase (DCXR) is increased in prostate cancer. Also, when compared with normal skin, a virtual northern blot shows increased expression of DCXR in melanomas...
  77. ncbi request reprint Desmoplastic and spindle cell melanomas express protein markers of the neural crest but not of later committed stages of Schwann cell differentiation
    Yve Huttenbach
    Section of Dermatopathology, Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
    J Cutan Pathol 29:562-8. 2002
    ..These features include a spindle-shaped morphology, neurotropism, and the expression of the low affinity nerve growth factor receptor (p75NGFR)...
  78. doi request reprint Sentinel node biopsy in patients with cutaneous melanoma of the head and neck: recurrence and survival study
    Fernando Gomez-Rivera
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 30:1284-94. 2008
    ..Controversy remains regarding the benefits of sentinel lymph node (SLN) biopsy for predicting survival in cutaneous melanoma of the head and neck (CMHN)...
  79. ncbi request reprint Segmental neurofibromatosis in association with a large congenital nevus and malignant melanoma
    Sean D Doherty
    Baylor College of Medicine, Houston, TX, USA
    Dermatol Online J 12:22. 2006
    ..The overlapping presentation suggests a common etiologic link between neurofibromatosis and large congenital nevi and the possibility that neurofibromatosis increases the risk of melanoma with large congenital nevi...
  80. ncbi request reprint Biochemotherapy in patients with metastatic anorectal mucosal melanoma
    Kevin B Kim
    Department of Melanoma Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston Texas 77030, USA
    Cancer 100:1478-83. 2004
    ..Patients with metastatic anorectal melanoma generally have an unfavorable prognosis, but no effective systemic therapy has been reported...
  81. ncbi request reprint Cytokeratin 7 and 20 expression in epithelioid sarcoma
    Scott D Humble
    Department of Pathology, University of South Alabama Medical Center, Mobile, Alabama, USA
    J Cutan Pathol 30:242-6. 2003
    ..Immunohistochemically, the neoplastic cells are typically positive for vimentin, low molecular weight cytokeratin (CAM5.2) and epithelial membrane antigen (EMA)...
  82. ncbi request reprint Mycosis fungoides-like reaction in a patient treated with Gleevec
    Sandra H Clark
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Cutan Pathol 30:279-81. 2003
    ..Currently, Gleevec is also being used in protocols for treatment of other malignancies such as melanoma. A few, non-descript cutaneous eruptions have been reported in patients receiving Gleevec...
  83. doi request reprint Cutaneous and subcutaneous metastases of gastrointestinal stromal tumors: a series of 5 cases with molecular analysis
    Wei Lien Wang
    Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Am J Dermatopathol 31:297-300. 2009
    ..Cutaneous metastases seem to be a late complication of GIST, but their presence does not necessarily herald a rapid demise of the patient...
  84. ncbi request reprint Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions
    Doina Ivan
    Department of Pathology, University of Texas, Houston, TX, USA
    Mod Pathol 17:811-8. 2004
    ..Also, the relative high expression of Jab1 in metastatic melanoma, associated with low levels of p27, suggests that Jab1 may be involved in survival and proliferation of metastatic melanoma cells...
  85. ncbi request reprint Atypical cells in human cutaneous re-excision scars for melanoma express p75NGFR, C56/N-CAM and GAP-43: evidence of early Schwann cell differentiation
    Octavio Trejo
    Department of Pathology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Cutan Pathol 29:397-406. 2002
    ..Little is known about the derivation of these cells. Because the normal cutaneous wound-healing process is reparative, we hypothesized that these atypical cells may be reactive proliferating Schwann cell precursors...
  86. ncbi request reprint Severe periorbital edema secondary to STI571 (Gleevec)
    Bita Esmaeli
    Ophthalmology Section, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 95:881-7. 2002
    ....
  87. ncbi request reprint Severe architectural disorder is a potential pitfall in the diagnosis of small melanocytic lesions
    Carlos A Torres-Cabala
    Department of Pathology, UT MD Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 37:860-5. 2010
    ..Little is known about the significance of severe architectural disorder in small melanocytic lesions with features of dysplastic nevi (DN)...
  88. ncbi request reprint Loss of MDA-7 expression with progression of melanoma
    Julie A Ellerhorst
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4095, USA
    J Clin Oncol 20:1069-74. 2002
    ..As a secondary objective, we analyzed MDA-7 protein expression in primary melanomas for correlation with predictors of outcome and with survival...
  89. doi request reprint An update on reporting histopathologic prognostic factors in melanoma
    Doina Ivan
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Arch Pathol Lab Med 135:825-9. 2011
    ..Thus, thorough reporting of histopathologic parameters, especially in the initial biopsies, is a critical component of both diagnosis and staging...
  90. ncbi request reprint Merkel cell carcinoma of the eyelid with a positive sentinel node
    Bita Esmaeli
    Ophthalmology Section, Department of Plastic Surgery, Box 443, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Arch Ophthalmol 120:646-8. 2002
  91. ncbi request reprint Renal cell carcinoma marker (RCC-Ma) is specific for cutaneous metastasis of renal cell carcinoma
    Ashley G Perna
    Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
    J Cutan Pathol 34:381-5. 2007
    ..RCC-Ma expression is relatively specific for primary clear cell renal cell carcinoma. Its expression in cutaneous metastasis of renal cell carcinoma (MRCC) and other cutaneous clear cell lesions has not been studied...
  92. ncbi request reprint Mortality risk from squamous cell skin cancer
    Gary L Clayman
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 23:759-65. 2005
    ..To identify nonmelanoma skin cancer patients with squamous cell carcinoma (SCC) who are at greatest risk of disease-specific mortality...
  93. ncbi request reprint Conjunctival melanoma with a positive sentinel lymph node
    Bita Esmaeli
    Department of Plastic Surgery, MD Anderson Cancer Center, Houstin, TX 77030, USA
    Arch Ophthalmol 121:1779-83. 2003
  94. ncbi request reprint Phase I studies of imatinib mesylate combined with cisplatin and irinotecan in patients with small cell lung carcinoma
    Faye M Johnson
    Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer 106:366-74. 2006
    ..In the current study, the authors investigated the feasibility of combining these drugs in the treatment of patients with SCLC...
  95. ncbi request reprint Reduction of adhesions with composite AlloDerm/polypropylene mesh implants for abdominal wall reconstruction
    Charles E Butler
    Department of Plastic Surgery, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Plast Reconstr Surg 114:464-73. 2004
    ....
  96. ncbi request reprint Phase I trial of preoperative doxorubicin-based concurrent chemoradiation and surgical resection for localized extremity and body wall soft tissue sarcomas
    Peter W T Pisters
    Multidisciplinary Sarcoma Center, Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030 4009, USA
    J Clin Oncol 22:3375-80. 2004
    ....
  97. doi request reprint Lack of maturation with anti-leptin receptor antibody in melanoma but not in nevi
    A Hafeez Diwan
    Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Mod Pathol 22:103-6. 2009
    ....
  98. ncbi request reprint Adult Langerhans cell histiocytosis limited to the skin
    Asha Singh
    Department of Dermatology, University of Texas M D Anderson Cancer Center, Houston, Tex 77030, USA
    Dermatology 207:157-61. 2003
    ..While dermatological manifestations occur in as many as 50% of cases, disease limited to the skin is uncommon among reported cases of adult LCH...
  99. ncbi request reprint Growth factor receptor expression in orbital lymphangioma: possible therapeutic implications
    Bita Esmaeli
    Ophthalmology Section, Department of Plastic Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Orbit 23:263-9. 2004
    ..To examine the expression of molecules targeted by imatinib mesylate (STI571;Gleevec) and epidermal growth factor receptor (EGFR) inhibitors in orbital lymphangiomas...
  100. ncbi request reprint Adjuvant irradiation for axillary metastases from malignant melanoma
    Matthew T Ballo
    Departments of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 52:964-72. 2002
    ..To evaluate the outcome and treatment-related toxicity for patients with axillary lymph node metastases from malignant melanoma treated with surgery and radiation, with or without systemic therapy...
  101. doi request reprint Transient iatrogenic immunodeficiency-related B-cell lymphoproliferative disorder of the skin in a patient with mycosis fungoides/Sézary syndrome
    Jonathan L Curry
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Cutan Pathol 38:295-7. 2011
    ..As far as we are aware, this is the first report of an Epstein-Barr virus-associated B-cell lymphoproliferative disorder, secondary to methotrexate therapy in a patient with mycosis fungoides/Sézary syndrome...