Affiliation: The Chicago Medical School
- BTF3 is evolutionarily conserved in fission yeastJ Potashkin
Department of Pharmacology and Molecular Biology, Finch University of Health Sciences The Chicago Medical School, IL 60064, USA
Biochim Biophys Acta 1308:182-4. 1996....
- Mutations in the large subunit of U2AF disrupt pre-mRNA splicing, cell cycle progression and nuclear structureM Beales
Department of Cellular and Molecular Pharmacology, Finch University of Health Sciences The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
Yeast 16:1001-13. 2000..These results suggest that normal functioning of spU2AF(59) may be essential not only for pre-mRNA splicing but also for the maintenance of proper nuclear structure and normal cell cycle progression...
- U2AF homolog required for splicing in vivoJ Potashkin
Department of Pharmacology and Molecular Biology, University of Health Sciences, Chicago Medical School, IL 60064
Science 262:573-5. 1993..Thus, this study provides evidence that a U2AF homolog participates in RNA processing in vivo...
- Molecular characterization of a novel fission yeast gene spUAP2 that interacts with the splicing factor spU2AF59R McKinney
Department of Pharmacology and Molecular Biology, Finch University of Health Sciences, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
Curr Genet 32:323-30. 1997..Interaction also requires the arginine/serine-rich region and the first RRM of spU2AF59. A null allele of the gene for spUAP2 is lethal...
- The small subunit of the splicing factor U2AF is conserved in fission yeastK Wentz-Hunter
Department of Pharmacology and Molecular Biology, Finch University of Health Sciences The Chicago Medical School, North Chicago, IL 60064, USA
Nucleic Acids Res 24:1849-54. 1996..The predicted molecular mass of the spU2AF small subunit is 23 kDa. The region of spU2AF59 that interacts with spU2AF23 is similar to the region in which the human small and large subunits interact...
- Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutantsJ Potashkin
Department of Cellular and Molecular Pharmacology, Finch University of Health Sciences, The Chicago Medical School, North Chicago, IL 60064, USA
Curr Genet 34:153-63. 1998..These results suggest a connection between pre-mRNA splicing and the control of cell division in fission yeast...
- Conserved Wat1/Pop3 WD-repeat protein of fission yeast secures genome stability through microtubule integrity and may be involved in mRNA maturationI L Ochotorena
Laboratory of Cell Regulation, Imperial Cancer Research Fund, London, UK
J Cell Sci 114:2911-20. 2001..The results suggest that Wat1 plays a role in mRNA maturation as a coupling protein between splicing and synthesis and/or stabilisation...
- Pre-mRNA splicing mutants of Schizosaccharomyces pombeJ Potashkin
Cold Spring Harbor Laboratory, New York 11724
EMBO J 8:551-9. 1989..Crosses among the mutants place them in three complementation groups. The mutants have been named prp1, prp2 and prp3...
- A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch siteO Gozani
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
Mol Cell Biol 18:4752-60. 1998..Together, our data are consistent with a model in which U2AF binds to the pyrimidine tract in the E complex and then interacts with SAP 155 to recruit U2 snRNP to the BPS...
- The genome sequence of Schizosaccharomyces pombeV Wood
The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nature 415:871-80. 2002....