Daniel L Popkin

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner
    Daniel L Popkin
    Department of Immunology and Microbial Sciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell Host Microbe 9:212-22. 2011
  2. ncbi Expanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: protein production, antibody production, and in vivo assessment of biological function of genes of interest
    Daniel L Popkin
    The Scripps Research Institute, Department of Immunology and Microbial Sciences IMM 6, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    J Virol 85:7928-32. 2011
  3. ncbi Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection
    Amanda L Blasius
    Department of Genetics, The Scripps Research Institute, La Jolla, California, USA
    PLoS Pathog 8:e1002915. 2012

Collaborators

  • Stefan Kunz
  • Amanda L Blasius
  • Michael B Oldstone
  • Brian M Sullivan
  • Philippe Krebs

Detail Information

Publications3

  1. ncbi Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner
    Daniel L Popkin
    Department of Immunology and Microbial Sciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell Host Microbe 9:212-22. 2011
    ..These results support in vivo targeting of Mbtps1 in the treatment of arenavirus infections and demonstrate a critical role for dendritic cells in persistent viral infections...
  2. ncbi Expanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: protein production, antibody production, and in vivo assessment of biological function of genes of interest
    Daniel L Popkin
    The Scripps Research Institute, Department of Immunology and Microbial Sciences IMM 6, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA
    J Virol 85:7928-32. 2011
    ..These findings demonstrate the utility of tripartite LCMV in vitro and in vivo to study genes in the context of a well-defined model system...
  3. ncbi Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection
    Amanda L Blasius
    Department of Genetics, The Scripps Research Institute, La Jolla, California, USA
    PLoS Pathog 8:e1002915. 2012
    ..Ultimately, infection persisted in feeble mice. We conclude that pDCs are likely required for efficient T cell priming and subsequent viral clearance. Our data suggest that reduced pDC functionality may lead to chronic infection...