Melissa Pope

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Dendritic cells as a conduit to improve HIV vaccines
    Melissa Pope
    Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY 10021, USA
    Curr Mol Med 3:229-42. 2003
  2. ncbi request reprint The enigma of dendritic cell-immunodeficiency virus interplay
    I Frank
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    Curr Mol Med 2:229-48. 2002
  3. ncbi request reprint CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells
    Natalia Teleshova
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    J Immunol 173:1647-57. 2004
  4. ncbi request reprint Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses
    Ines Frank
    Center for Biomedical Research, Population Council, New York, New York 10021, USA
    J Acquir Immune Defic Syndr 34:7-19. 2003
  5. ncbi request reprint Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells
    Davorka Messmer
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Immunol 169:4172-82. 2002
  6. pmc Immunomodulatory effects of HSV-2 infection on immature macaque dendritic cells modify innate and adaptive responses
    Silvia Peretti
    Center for Biomedical Research, Population Council, 1230 York Ave, New York, NY 10021
    Blood 106:1305-13. 2005
  7. pmc Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus
    Ralf Ignatius
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    J Virol 76:9787-97. 2002
  8. ncbi request reprint Immunodeficiency virus exploitation of dendritic cells in the early steps of infection
    Natalia Teleshova
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    J Leukoc Biol 74:683-90. 2003
  9. ncbi request reprint Short-term Flt3L treatment effectively mobilizes functional macaque dendritic cells
    Natalia Teleshova
    Population Council, 1230 York Avenue, New York, NY 10021, USA
    J Leukoc Biol 75:1102-10. 2004
  10. ncbi request reprint Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types
    Thomas J Ketas
    Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 19:177-86. 2003

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Dendritic cells as a conduit to improve HIV vaccines
    Melissa Pope
    Center for Biomedical Research, Population Council, 1230 York Avenue, New York, NY 10021, USA
    Curr Mol Med 3:229-42. 2003
    ....
  2. ncbi request reprint The enigma of dendritic cell-immunodeficiency virus interplay
    I Frank
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    Curr Mol Med 2:229-48. 2002
    ....
  3. ncbi request reprint CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells
    Natalia Teleshova
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    J Immunol 173:1647-57. 2004
    ....
  4. ncbi request reprint Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses
    Ines Frank
    Center for Biomedical Research, Population Council, New York, New York 10021, USA
    J Acquir Immune Defic Syndr 34:7-19. 2003
    ..Further studies using AT-2 inactivated virus may help to define better the details of the virus-DC interactions critical for infection versus induction of antiviral immune responses...
  5. ncbi request reprint Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells
    Davorka Messmer
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Immunol 169:4172-82. 2002
    ....
  6. pmc Immunomodulatory effects of HSV-2 infection on immature macaque dendritic cells modify innate and adaptive responses
    Silvia Peretti
    Center for Biomedical Research, Population Council, 1230 York Ave, New York, NY 10021
    Blood 106:1305-13. 2005
    ..This work affords the basis for future macaque studies to explore how HSV-2 impacts the efficacy of strategies being developed to prevent HIV transmission...
  7. pmc Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus
    Ralf Ignatius
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    J Virol 76:9787-97. 2002
    ..This may have important implications for the subsequent dissemination of infection and/or induction of antiretroviral immunity...
  8. ncbi request reprint Immunodeficiency virus exploitation of dendritic cells in the early steps of infection
    Natalia Teleshova
    Center for Biomedical Research, Population Council, New York, NY 10021, USA
    J Leukoc Biol 74:683-90. 2003
    ....
  9. ncbi request reprint Short-term Flt3L treatment effectively mobilizes functional macaque dendritic cells
    Natalia Teleshova
    Population Council, 1230 York Avenue, New York, NY 10021, USA
    J Leukoc Biol 75:1102-10. 2004
    ..This has important implications for improved DC-targeting vaccine strategies to prevent infection with human immunodeficiency virus and other pathogens...
  10. ncbi request reprint Entry inhibitors SCH-C, RANTES, and T-20 block HIV type 1 replication in multiple cell types
    Thomas J Ketas
    Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 19:177-86. 2003
    ....
  11. ncbi request reprint Transmission, acute HIV-1 infection and the quest for strategies to prevent infection
    Melissa Pope
    Center for Biomedical Research, Population Council, 1230 York Avenue, New York 10021, USA
    Nat Med 9:847-52. 2003
    ..Research on mucosal barriers and the events immediately after heterosexual transmission that precede this acute stage could facilitate the development of effective microbicides and vaccines...
  12. ncbi request reprint Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells
    Sylvie Beaulieu
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University and Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Medical College, Cornell University, New York, NY 10021, USA
    J Immunol 169:2925-36. 2002
    ..We postulate that expression of CCR3 may underlie situations where both DCs and eosinophils accumulate in vivo, such as the lesions of patients with Langerhans cell granulomatosis...
  13. pmc Exploiting dendritic cells to improve vaccine efficacy
    Ralph M Steinman
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York, USA
    J Clin Invest 109:1519-26. 2002
  14. ncbi request reprint Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses
    Erin Mehlhop
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    J Immunol Methods 260:219-34. 2002
    ..Thus, the cocktail represents a particularly potent and useful stimulus for the generation of efficacious immunostimulatory macaque DCs...
  15. ncbi request reprint Nefarious abuse
    Melissa Pope
    Nat Immunol 4:729-30. 2003
  16. ncbi request reprint Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
    Ronald S Veazey
    Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, USA
    Nat Med 9:343-6. 2003
    ..Lower amounts of b12 were less effective, suggesting that protection was dose dependent. These observations support the concept that viral entry inhibitors can help prevent the sexual transmission of HIV-1 to humans...
  17. ncbi request reprint Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells
    Stuart G Turville
    Centre for Virus Research, Westmead Millennium Institute, Sydney, Australia
    Blood 103:2170-9. 2004
    ..Thus, the controversy of DCs being infected or not infected for the mechanics of viral transfer to CD4+ lymphocytes can be addressed as a function of time...
  18. pmc Human immunodeficiency virus type 1 attachment, coreceptor, and fusion inhibitors are active against both direct and trans infection of primary cells
    Thomas J Ketas
    Progenics Pharmaceuticals, Inc, Tarrytown, NY 10591, USA
    J Virol 77:2762-7. 2003
    ..Although minor cell-type-dependent differences in potency were observed, each inhibitor was active on each cell type and trans infection was similarly vulnerable to inhibition at each stage of the fusion cascade...
  19. pmc Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue
    Qinxue Hu
    Department of Cellular and Molecular Medicine, Infectious Diseases, St George s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK
    J Exp Med 199:1065-75. 2004
    ..Our identification of the predominant receptors involved in HIV-1 infection and dissemination within human cervical tissue highlight important targets for microbicide development...
  20. pmc Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN
    Li Wu
    HIV Drug Resistance Program, Laboratory of Genomic Diversity, and Basic Research Program, Science Applications International Corporation Frederick, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
    Proc Natl Acad Sci U S A 99:1568-73. 2002
    ....
  21. pmc Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins
    David R Morcock
    AIDS Vaccine Program, SAIC Frederick, NCI Frederick, Building 535, 5th Floor, PO Box B, Frederick, MD 21702, USA
    J Virol 79:1533-42. 2005
    ....