Affiliation: The Rockefeller University
- Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropismM Pope
Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
J Virol 71:8001-7. 1997..Our findings do not support the conclusion that subtype E strains have a preferential tropism for DCs, suggesting that other explanations for the rapid heterosexual spread of subtype E strains in Asia should be considered...
- Mucosal dendritic cells and immunodeficiency virusesM Pope
Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA
J Infect Dis 179:S427-30. 1999..Further studies using the macaque model are underway to elucidate the role of DCs in the transmission and spread of HIV infection...
- The interaction of immunodeficiency viruses with dendritic cellsR M Steinman
Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Curr Top Microbiol Immunol 276:1-30. 2003..The interaction of HIV-1 and SIV with DCs is therefore intricate but pertinent to understanding how these viruses disrupt immune function and elicit immune responses...
- CpG-C ISS-ODN activation of blood-derived B cells from healthy and chronic immunodeficiency virus-infected macaquesN Teleshova
Population Council, 1230 York Avenue, New York, NY 10021, USA
J Leukoc Biol 79:257-67. 2006..The ability of C274 to stimulate B cells and DCs in healthy and infected monkeys suggests its possible use as a broad-acting adjuvant to be applied in the rhesus macaque model for the development of preventative and therapeutic vaccines...
- Consequences of dendritic cell (DC)-immunodeficiency virus interactions: chemically inactivated virus as a model for studying antigen presentation and virus transmission by primate DCsI Frank
Population Council, Center for Biomedical Research, New York, NY 10021, USA
Immunobiology 204:622-8. 2001....
- A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vesselsG J Randolph
Department of Pathology, Cornell University Medical College, 1300 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 95:6924-9. 1998....
- Macaque dendritic cells infected with SIV-recombinant canarypox ex vivo induce SIV-specific immune responses in vivoL Villamide-Herrera
Center for Biomedical Research, Population Council, New York, New York 10021, USA
AIDS Res Hum Retroviruses 20:871-84. 2004..This pilot study provides the proof of principle that sc injected ex vivo SIV-recombinant canarypox-infected DCs safely induce low-level SIV-specific immune responses in vivo...
- The enigma of dendritic cell-immunodeficiency virus interplayI Frank
Center for Biomedical Research, Population Council, New York, NY 10021, USA
Curr Mol Med 2:229-48. 2002....
- Infectious and whole inactivated simian immunodeficiency viruses interact similarly with primate dendritic cells (DCs): differential intracellular fate of virions in mature and immature DCsI Frank
Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York, 10021, USA
J Virol 76:2936-51. 2002....
- The immunodeficiency virus coreceptor, Bonzo/STRL33/TYMSTR, is expressed by macaque and human skin- and blood-derived dendritic cellsR Ignatius
Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021, USA
AIDS Res Hum Retroviruses 16:1055-9. 2000..Therefore, Bonzo/STRL33/TYMSTR is expressed in DCs and T cells that can play a role in the transmission of immunodeficiency viruses...
- Human immunodeficiency virus type 1 Nef mediates activation of STAT3 in immature dendritic cellsD Messmer
North Shore LIJ Research Institute, Manhasset, New York 11030, USA
AIDS Res Hum Retroviruses 18:1043-50. 2002..This highlights how Nef can signal primary immature DCs, suggesting one way in which Nef may modulate immature DCs to drive virus replication in the DC-T cell milieu...
- Culture and comparison of feline myeloid dendritic cells vs macrophagesW S Sprague
Department of Microbiology, Immunology and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523 1619, USA
J Comp Pathol 133:136-45. 2005..Additionally, macrophages cultured with GM-CSF provide a potential means of studying the mechanism of immunosuppression in cats...
- Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptorsA Granelli-Piperno
Theodor Kocher Institute, Bern, Switzerland
J Exp Med 184:2433-8. 1996..DCs express more CCR5 and CXCR4 mRNA than T cells. Therefore, while HIV-1 does not replicate efficiently in mature DCs, viral entry can be active and can be blocked by chemokines that act on known receptors for M- and T-tropic virus...