JOHN M POLICH

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi request reprint P3a and P3b auditory ERPs in HIV patients receiving anti-viral medication
    John Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Clin Electroencephalogr 33:97-101. 2002
  2. ncbi request reprint Clinical application of the P300 event-related brain potential
    John Polich
    Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Phys Med Rehabil Clin N Am 15:133-61. 2004
  3. ncbi request reprint Neuropsychology and neuropharmacology of P3a and P3b
    John Polich
    Cognitive Electrophysiology Laboratory, Department of Neuropharmacology TPC 10, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Psychophysiol 60:172-85. 2006
  4. ncbi request reprint P3a from visual stimuli: typicality, task, and topography
    John Polich
    Department of Neuropharmacology TPC 10, The Scripps Research Institute, La Jolla, California 92037, USA
    Brain Topogr 15:141-52. 2003
  5. ncbi request reprint Alcoholism risk and the P300 event-related brain potential: modality, task, and gender effects
    Clarissa Reese
    The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Brain Cogn 53:46-57. 2003
  6. pmc Occipital gamma activation during Vipassana meditation
    B Rael Cahn
    Division of Geriatric Psychiatry, Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
    Cogn Process 11:39-56. 2010
  7. ncbi request reprint Meta-analysis of P300 normative aging studies
    J Polich
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA
    Psychophysiology 33:334-53. 1996
  8. ncbi request reprint P300 as a clinical assay: rationale, evaluation, and findings
    J Polich
    Department of Neuropharmacology, TPC 10, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Int J Psychophysiol 38:3-19. 2000
  9. ncbi request reprint Neuroelectric assessment of HIV: EEG, ERP, and viral load
    J Polich
    Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Int J Psychophysiol 38:97-108. 2000
  10. ncbi request reprint Alcoholism risk, tobacco smoking, and P300 event-related potential
    John Polich
    Cognitive Electrophysiology Laboratory, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Clin Neurophysiol 115:1374-83. 2004

Collaborators

Detail Information

Publications37

  1. ncbi request reprint P3a and P3b auditory ERPs in HIV patients receiving anti-viral medication
    John Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Clin Electroencephalogr 33:97-101. 2002
    ..No reliable P3b effects were obtained. The findings suggest that P3a rather than P3b may be a more sensitive measure of cognitive impairment in HIV patients on anti-viral medication...
  2. ncbi request reprint Clinical application of the P300 event-related brain potential
    John Polich
    Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Phys Med Rehabil Clin N Am 15:133-61. 2004
    ..Use of P300 as a clinical evaluation tool should be revisited with contemporary theory, methods, and analysis procedures because a reliable neuroelectric measure of mental function would redefine the assessment of cognitive disorders...
  3. ncbi request reprint Neuropsychology and neuropharmacology of P3a and P3b
    John Polich
    Cognitive Electrophysiology Laboratory, Department of Neuropharmacology TPC 10, The Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Psychophysiol 60:172-85. 2006
    ..The findings suggest that the circuit underlying ERP generation is influenced in a different ways for acute intake and varies between chronic use levels across drugs. Theoretical implications are assessed...
  4. ncbi request reprint P3a from visual stimuli: typicality, task, and topography
    John Polich
    Department of Neuropharmacology TPC 10, The Scripps Research Institute, La Jolla, California 92037, USA
    Brain Topogr 15:141-52. 2003
    ..The findings suggest that stimulus context as defined by the target/standard discrimination difficulty rather than stimulus novelty determines P3a generation...
  5. ncbi request reprint Alcoholism risk and the P300 event-related brain potential: modality, task, and gender effects
    Clarissa Reese
    The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Brain Cogn 53:46-57. 2003
    ..These findings suggest that P300 amplitude reflects risk-for-alcoholism in male and female young adults, but the specific task conditions and electrode location affect the strength of risk group differences...
  6. pmc Occipital gamma activation during Vipassana meditation
    B Rael Cahn
    Division of Geriatric Psychiatry, Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
    Cogn Process 11:39-56. 2010
    ..The findings suggest that long-term Vipassana meditation contributes to increased occipital gamma power related to long-term meditational expertise and enhanced sensory awareness...
  7. ncbi request reprint Meta-analysis of P300 normative aging studies
    J Polich
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA
    Psychophysiology 33:334-53. 1996
    ..It is concluded that P300 latency can provide useful information about cognitive aging but that specific variables must be considered to obtain more precise results...
  8. ncbi request reprint P300 as a clinical assay: rationale, evaluation, and findings
    J Polich
    Department of Neuropharmacology, TPC 10, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Int J Psychophysiol 38:3-19. 2000
    ..These results are discussed in terms of how to control inter-group ERP variability and the application of normative P300 data in clinical settings...
  9. ncbi request reprint Neuroelectric assessment of HIV: EEG, ERP, and viral load
    J Polich
    Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Int J Psychophysiol 38:97-108. 2000
    ..HIV infection negatively affected central nervous system function as measured by EEG and cognitive ERPs in a manner that suggests decreased arousal and increased fatigue in HIV patients...
  10. ncbi request reprint Alcoholism risk, tobacco smoking, and P300 event-related potential
    John Polich
    Cognitive Electrophysiology Laboratory, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Clin Neurophysiol 115:1374-83. 2004
    ..These effects are inconsistent, and how P300 is affected by tobacco smoking in the context of alcoholism risk is unknown. The present study used P300 to examine the inter-relationship between alcoholism heritability and smoking status...
  11. pmc Updating P300: an integrative theory of P3a and P3b
    John Polich
    Cognitive Electrophysiology Laboratory, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Clin Neurophysiol 118:2128-48. 2007
    ..Neuroinhibition is suggested as an overarching theoretical mechanism for P300, which is elicited when stimulus detection engages memory operations...
  12. ncbi request reprint Alzheimer's disease and P300: review and evaluation of task and modality
    John Polich
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Alzheimer Res 2:515-25. 2005
    ..Theoretical and practical implications are reviewed...
  13. ncbi request reprint P300, alcoholism heritability, and stimulus modality
    J Polich
    Department of Neuropharmacology TPC 10, The Scripps Research Institute, La Jolla, CA 92037, USA
    Alcohol 17:149-56. 1999
    ..When taken in conjunction with previous findings, the present results suggest that P300 amplitude from auditory stimuli may not be as reliable as ERPs from visual stimuli for the assessment of alcoholism heritability...
  14. ncbi request reprint P300 and handedness: on the possible contribution of corpus callosal size to ERPs
    J Polich
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA, USA
    Psychophysiology 35:497-507. 1998
    ..When considered in the context of corpus callosal size differences for left-versus right-handed and male versus female participants, the findings suggest that the P300 reflects callosal size and interhemispheric transmission efficacy...
  15. ncbi request reprint P300, stimulus intensity, modality, and probability
    J Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Psychophysiol 23:55-62. 1996
    ..The findings suggest that stimulus intensity contributes to both P300 amplitude and latency measures in important ways and are discussed in relation to the use of ERPs in applied contexts...
  16. ncbi request reprint P300 topography and modality effects from a single-stimulus paradigm
    J Polich
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA
    Psychophysiology 33:747-52. 1996
    ..The findings suggest that the single-stimulus paradigm may be useful in experimental and applied contexts that require very simple ERP task conditions...
  17. ncbi request reprint P300 and probability: comparison of oddball and single-stimulus paradigms
    J Polich
    Department of Neuropharmacology, Scripps Research Institute TPC 10, La Jolla, CA 92037, USA
    Int J Psychophysiol 25:169-76. 1997
    ..The implications of the single-stimulus technique are discussed in terms of applied contexts that require very simple ERP task conditions...
  18. ncbi request reprint P300 sequence effects, probability, and interstimulus interval
    J Polich
    Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Physiol Behav 61:843-9. 1997
    ..The theoretical implications of the findings are discussed in the context of applied testing situations...
  19. ncbi request reprint EEG and ERP assessment of normal aging
    J Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, La Jolla, CA 92037, USA
    Electroencephalogr Clin Neurophysiol 104:244-56. 1997
    ..The results suggest that age contributes to EEG power shifts, and that such changes significantly affect age-related variability of the P3 ERP component...
  20. ncbi request reprint On the relationship between EEG and P300: individual differences, aging, and ultradian rhythms
    J Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, La Jolla, CA 92037, USA
    Int J Psychophysiol 26:299-317. 1997
    ..Taken together, the findings from all three study indicate that background EEG variation contributes significantly to the individual variability of the P300 ERP. Theoretical and applied implications of the findings are discussed...
  21. ncbi request reprint P300 topography of amplitude/latency correlations
    J Polich
    Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA
    Brain Topogr 9:275-82. 1997
    ..Taken together, the findings suggest that analysis of amplitude/latency correlational relationships can provide information about ERP component generation. Theoretical implications are discussed...
  22. ncbi request reprint P300 and long-term physical exercise
    J Polich
    Department of Neuropharmacology TPC 10, Scripps Research Institute, La Jolla, CA 92037, USA
    Electroencephalogr Clin Neurophysiol 103:493-8. 1997
    ..The findings suggest that a history of intensive physical exercise affects P300 amplitude. Theoretical mechanisms are discussed...
  23. ncbi request reprint P3a, perceptual distinctiveness, and stimulus modality
    M D Comerchero
    Department of Psychology, University of California, San Diego, La Jolla, CA 92037, USA
    Brain Res Cogn Brain Res 7:41-8. 1998
    ..Theoretical implications are discussed...
  24. ncbi request reprint P3a from visual stimuli: task difficulty effects
    Galen F Hagen
    Department of Psychology, University of California, San Diego, La Jolla, CA 92093, USA
    Int J Psychophysiol 59:8-14. 2006
    ..The findings suggest that increased perceptual discrimination difficulty between the target and standard stimuli increases P3a amplitude. Theoretical implications are discussed...
  25. ncbi request reprint P3a from auditory white noise stimuli
    Lindsey A Combs
    Department of Psychology, University of California, San Diego, La Jolla, CA, USA
    Clin Neurophysiol 117:1106-12. 2006
    ..P3a and P3b event-related brain potentials (ERPs) were elicited with an auditory 3-stimulus (target, distracter, standard) paradigm in which subjects responded only to the target...
  26. pmc Workload assessment of computer gaming using a single-stimulus event-related potential paradigm
    Brendan Z Allison
    Cognitive Electrophysiology Laboratory, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States
    Biol Psychol 77:277-83. 2008
    ....
  27. pmc Affective valence, stimulus attributes, and P300: color vs. black/white and normal vs. scrambled images
    Maya E Cano
    Department of Psychology, University of California, San Diego, La Jolla, CA, USA
    Int J Psychophysiol 71:17-24. 2009
    ..The findings suggest that P300 amplitude is sensitive to affective picture valence in the absence of stimulus arousal differences, and that stimulus color contributes to ERP valence effects...
  28. pmc Binge drinking effects on EEG in young adult humans
    Kelly E Courtney
    The Scripps Research Institute, Molecular and Integrative Neurosciences Department, La Jolla, CA 92037, USA
    Int J Environ Res Public Health 7:2325-36. 2010
    ..Binge drinking appears to be associated with a specific pattern of brain electrical activity in young adults that may reflect the future development of alcoholism...
  29. pmc Meditation (Vipassana) and the P3a event-related brain potential
    B Rael Cahn
    Medical School, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Int J Psychophysiol 72:51-60. 2009
    ....
  30. pmc Evidence for attentional gradient in the serial position memory curve from event-related potentials
    Allen Azizian
    The Scripps Research Institute, La Jolla, California 92037, USA
    J Cogn Neurosci 19:2071-81. 2007
    ..Recency effects appear to index operations determined by the anticipation of the last stimulus presentation, which occurred for both recalled and unrecalled memory items. Theoretical implications are discussed...
  31. pmc Affective visual event-related potentials: arousal, valence, and repetition effects for normal and distorted pictures
    Bella Rozenkrants
    Department of Psychology, University of California, San Diego, La Jolla, CA, USA
    Int J Psychophysiol 67:114-23. 2008
    ..Stimulus repetition engages memory for previous normal picture items but is not influenced by affective category. Theoretical implications are discussed...
  32. pmc Affective ERP processing in a visual oddball task: arousal, valence, and gender
    Bella Rozenkrants
    Department of Psychology, University of California, San Diego, La Jolla, CA, USA
    Clin Neurophysiol 119:2260-5. 2008
    ..To assess affective event-related brain potentials (ERPs) using visual pictures that were highly distinct on arousal level/valence category ratings and a response task...
  33. ncbi request reprint P300 stimulus sequence effects in children and adults
    Orna Gill
    University of California, San Diego, USA
    Percept Mot Skills 94:509-20. 2002
    ..The findings suggest that immediate memory for stimulus sequences is fully developed in young children, although long-term memory is not...
  34. ncbi request reprint Olfactory, auditory, and visual ERPs from single trials: no evidence for habituation
    Spencer Wetter
    Department of Psychology, San Diego State University, and SDSU UCSD Joint Doctoral Program, 6363 Alvarado Court Ste 101, San Diego, CA 92120 4913, USA
    Int J Psychophysiol 54:263-72. 2004
    ..Application of single-stimulus paradigm to olfactory ERP methods is supported...
  35. pmc Binge drinking in young adults: Data, definitions, and determinants
    Kelly E Courtney
    Department of Psychology, San Diego State University, CA, USA
    Psychol Bull 135:142-56. 2009
    ..Theoretical implications are discussed on how binge drinking may alter neurophysiological and neurocognitive function...
  36. ncbi request reprint Meditation states and traits: EEG, ERP, and neuroimaging studies
    B Rael Cahn
    Department of Neurosciences and Medical School, University of California, San Diego, CA, USA
    Psychol Bull 132:180-211. 2006
    ..Psychological and clinical effects of meditation are summarized, integrated, and discussed with respect to neuroimaging data...
  37. ncbi request reprint P300 from one-, two-, and three-stimulus auditory paradigms
    J Katayama
    Faculty of Education, Hokkaido University, Sapporo, Japan
    Int J Psychophysiol 23:33-40. 1996
    ..The results suggest that P300 was produced by the same neural and cognitive mechanisms across tasks. The possible utility of each paradigm in clinical testing is discussed...

Research Grants14

  1. Neuroelectric Assessment of Ecstasy Use in Young Adults
    John Polich; Fiscal Year: 2007
    ..Equal numbers of female and male subjects will be assessed in all phases. The proposed methods will characterize CNS differences from MDMA use to provide assessment of drug effects on cognition. ..
  2. Neuroelectric Assessment of MDMA (Ecstasy) Use in Adults
    John Polich; Fiscal Year: 2003
    ..These results will provide fundamental data on how MDMA use may alter CNS function. ..
  3. MARIJUANA CNS EFFECTS IN LOW- AND HIGH-RISK ADULTS
    John Polich; Fiscal Year: 2002
    ..The most sensitive and effective paradigms will provide reliable neuroelectric signatures that reflect marihuana's cognitive effects. ..
  4. Alcohol and Tobacco CNS Effects in Binge Drinkers
    JOHN M POLICH; Fiscal Year: 2010
    ....