Peter M Piermarini


Affiliation: The Ohio State University
Country: USA


  1. Kalsi M, Gillen C, Piermarini P. Heterologous Expression of Aedes aegypti Cation Chloride Cotransporter 2 (aeCCC2) in Xenopus laevis Oocytes Induces an Enigmatic Na⁺/Li⁺ Conductance. Insects. 2019;10: pubmed publisher
    ..It remains to be determined whether aeCCC2 directly mediates the Na⁺/Li⁺ conductance or whether heterologous expression of aeCCC2 stimulates an endogenous cation channel in the oocyte plasma membrane. ..
  2. Rusconi Trigueros R, Hopkins C, Denton J, Piermarini P. Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval Aedes aegypti. Insects. 2018;9: pubmed publisher
  3. Piermarini P, Inocente E, Acosta N, Hopkins C, Denton J, Michel A. Inward rectifier potassium (Kir) channels in the soybean aphid Aphis glycines: Functional characterization, pharmacology, and toxicology. J Insect Physiol. 2018;110:57-65 pubmed publisher
    ..We conclude that despite the apparent loss of Kir3 genes in aphid evolution, Kir channels are important to aphid survival and represent a promising target for the development of new insecticides. ..
  4. Piermarini P, Dunemann S, Rouhier M, Calkins T, Raphemot R, Denton J, et al. Localization and role of inward rectifier K(+) channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti. Insect Biochem Mol Biol. 2015;67:59-73 pubmed publisher
    ..The physiological role of AeKir3 in intracellular membranes of both stellate and principal cells remains to be determined. ..
  5. Yang Z, Statler B, Calkins T, Alfaro E, Esquivel C, Rouhier M, et al. Dynamic expression of genes encoding subunits of inward rectifier potassium (Kir) channels in the yellow fever mosquito Aedes aegypti. Comp Biochem Physiol B Biochem Mol Biol. 2017;204:35-44 pubmed publisher
    ..Altogether, the data provide the first comprehensive characterization of Kir mRNA expression in Ae. aegypti and offer insights into the putative physiological roles of Kir subunits in this important disease vector. ..
  6. Piermarini P, Hine R, Schepel M, Miyauchi J, Beyenbach K. Role of an apical K,Cl cotransporter in urine formation by renal tubules of the yellow fever mosquito (Aedes aegypti). Am J Physiol Regul Integr Comp Physiol. 2011;301:R1318-37 pubmed publisher
  7. Piermarini P, Rouhier M, Schepel M, Kosse C, Beyenbach K. Cloning and functional characterization of inward-rectifying potassium (Kir) channels from Malpighian tubules of the mosquito Aedes aegypti. Insect Biochem Mol Biol. 2013;43:75-90 pubmed publisher
    ..We conclude that in Aedes Malpighian tubules, Kir channels contribute to the majority of the barium-sensitive transepithelial transport of K(+)...
  8. Calkins T, Woods Acevedo M, Hildebrandt O, Piermarini P. The molecular and immunochemical expression of innexins in the yellow fever mosquito, Aedes aegypti: insights into putative life stage- and tissue-specific functions of gap junctions. Comp Biochem Physiol B Biochem Mol Biol. 2015;183:11-21 pubmed publisher
  9. Yang L, Piermarini P. Molecular expression of aquaporin mRNAs in the northern house mosquito, Culex pipiens. J Insect Physiol. 2017;96:35-44 pubmed publisher
    ..Our study is the first to characterize the molecular expression patterns of AQPs in C. pipiens, thus providing a foundation for future research elucidating the physiological and functional roles of AQPs in this important disease vector. ..

More Information


  1. Yang L, Denlinger D, Piermarini P. The diapause program impacts renal excretion and molecular expression of aquaporins in the northern house mosquito, Culex pipiens. J Insect Physiol. 2017;98:141-148 pubmed publisher
  2. Piermarini P, Esquivel C, Denton J. Malpighian Tubules as Novel Targets for Mosquito Control. Int J Environ Res Public Health. 2017;14: pubmed publisher
  3. Calkins T, DeLaat A, Piermarini P. Physiological characterization and regulation of the contractile properties of the mosquito ventral diverticulum (crop). J Insect Physiol. 2017;103:98-106 pubmed publisher
  4. Calkins T, Piermarini P. A Blood Meal Enhances Innexin mRNA Expression in the Midgut, Malpighian Tubules, and Ovaries of the Yellow Fever Mosquito Aedes aegypti. Insects. 2017;8: pubmed publisher
    ..Altogether, our results suggest that a blood meal influences the molecular expression of innexins in mosquitoes, but their specific physiological roles remain to be elucidated. ..