Research Topics
| Frank PesslerSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
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Detail Information
Publications
Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levelsSung Mun Jung
Division of Rheumatology, University of Pennsylvania, 3600 Spruce St, Philadelphia, PA 19104, USA
Arthritis Res Ther 9:R64. 2007..These results support a need for further studies of the efficacy of these extracts in the treatment of inflammatory arthropathies and suggest elevation of PGD2 levels as a novel mechanism for an anti-inflammatory agent...
Flexible DNA binding of the BTB/POZ-domain protein FBI-1Frank Pessler
Cold Spring Harbor Laboratory and Howard Hughes Medical Institute, Cold Spring Harbor, New York 11724, USA
J Biol Chem 278:29327-35. 2003....
Polyarthritis in a child with Rosai-Dorfman diseaseF Pessler
Division of Rheumatology, The Children s Hospital of Philadelphia, PA 19104, USA
Clin Exp Rheumatol 25:645-8. 2007..This report adds inflammatory arthritis to the extranodal manifestations of RDD in children and suggests that this disorder should be considered as a rare cause of fever with rash, lymphadenopathy and arthritis...
Anaphylactic reaction to goat's milk in a cow's milk-allergic infantFrank Pessler
Department of Pediatrics, New York University School of Medicine, Bellevue Hospital Center, New York, NY 10016, USA
Pediatr Allergy Immunol 15:183-5. 2004..Thus, the cross-allergenicity between cow's and goat's milk proteins can lead to life-threatening complications. Individuals allergic to cow's milk protein should avoid goat's milk and goat's milk products...
The spectrum of renal tubular acidosis in paediatric Sjögren syndromeF Pessler
Department of Pediatrics, Division of Rheumatology, The Children s Hospital of Philadelphia, PA 19104, USA
Rheumatology (Oxford) 45:85-91. 2006..Renal tubular acidosis (RTA) is a well-recognized extraglandular complication of adult Sjögren syndrome (SS) but has been reported only rarely in paediatric SS. We wished to describe the natural history of RTA in paediatric SS...
Sjögren syndrome in a child: favorable response of the arthritis to TNFalpha blockadeF Pessler
Division of Rheumatology, Department of Pediatrics, The Children s Hospital of Philadelphia, 3405 Civic Center Boulevard, Philadelphia, PA 19104, USA
Clin Rheumatol 25:746-8. 2006..In contrast to her other disease manifestations, the arthritis responded remarkably well to TNFalpha blockade, suggesting that TNFalpha blockers may have a role in the treatment of arthritis with pediatric SS...
NFAT transcription factors--new players in the pathogenesis of inflammatory arthropathies?F Pessler
Department of Pediatrics, Division of Rheumatology, The Children s Hospital of Philadelphia, 3405 Civic Center Boulevard, Philadelphia, PA 19104, USA
Autoimmun Rev 5:106-10. 2006..Specific anti-NFAT drug therapy may add to the pharmacologic armamentarium against rheumatoid arthritis, other inflammatory arthropathies, and related autoimmune disorders...
Identification of broadly discriminatory tissue biomarkers of synovitis with binary and multicategory receiver operating characteristic analysisA Ogdie
Division of Rheumatology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Biomarkers 15:183-90. 2010..44). Multicategory ROC analysis ranked Ki-67, subintimal CD68, and CD15 as discriminating best among all six sample groups, and thus identified them as the most broadly applicable markers...
Interstitial granulomatous lesions as part of the spectrum of presenting cutaneous signs in pediatric sarcoidosisEun J Kwon
School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Pediatr Dermatol 24:517-24. 2007....
Devic disease in a child with primary Sjögren syndromeBita Arabshahi
Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Child Neurol 21:285-6. 2006
A histomorphometric analysis of synovial biopsies from individuals with Gulf War Veterans' Illness and joint pain compared to normal and osteoarthritis synoviumF Pessler
Division of Rheumatology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Clin Rheumatol 27:1127-34. 2008..In summary, the GWVI and normal synovia were indistinguishable from each other and contained similar low-grade inflammatory cell populations consisting almost entirely of macrophages and T cells...
Diagnosing early rheumatoid arthritis (RA). What are the problems and opportunities?H R Schumacher
Department of Rheumatology, University of Pennsylvania Hospital, 3rd Ravdin Building, 34th and Spruce Street, Philadelphia, Pennsylvania, USA
Clin Exp Rheumatol 21:S15-9. 2003..We review this area, focusing on work from our own research and how this has guided our thinking...
Reciprocal regulation of the nuclear factor of activated T cells and HIV-1F Pessler
Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Genes Immun 5:158-67. 2004..Recent small-scale clinical trials have yielded optimistic results, suggesting roles for CsA after organ transplantation in HIV-1+ individuals and as adjunct treatment in stable early HIV-1 infection...
Increased angiogenesis and cellular proliferation as hallmarks of the synovium in chronic septic arthritisF Pessler
The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Arthritis Rheum 59:1137-46. 2008..To characterize histologic alterations and inflammatory infiltrates in the synovium of patients with chronic septic arthritis (SeA)...
Synovial biopsy in the evaluation of nonrheumatic systemic diseases causing arthritisH Ralph Schumacher
Curr Opin Rheumatol 20:61-5. 2008
