Satchidananda Panda

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Illumination of the melanopsin signaling pathway
    Satchidananda Panda
    Genomics Institute of Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 307:600-4. 2005
  2. ncbi request reprint Multiple photopigments entrain the Mammalian circadian oscillator
    Satchidananda Panda
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Neuron 53:619-21. 2007
  3. ncbi request reprint Melanopsin is required for non-image-forming photic responses in blind mice
    Satchidananda Panda
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 301:525-7. 2003
  4. pmc Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock
    Luciano DiTacchio
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Science 333:1881-5. 2011
  5. ncbi request reprint Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting
    Satchidananda Panda
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 298:2213-6. 2002
  6. pmc Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
    Megumi Hatori
    Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Cell Metab 15:848-60. 2012
  7. pmc Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines
    Rajesh Narasimamurthy
    Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 109:12662-7. 2012
  8. ncbi request reprint Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior
    M Fernanda Ceriani
    Institute of Childhood and Neglected Diseases, Department of Cell Biology ICND216, The Scripps Research Institute, La Jolla, California 92037, USA
    J Neurosci 22:9305-19. 2002
  9. pmc Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
    Christopher Vollmers
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 106:21453-8. 2009
  10. ncbi request reprint A functional genomics strategy reveals Rora as a component of the mammalian circadian clock
    Trey K Sato
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, California 92121, USA
    Neuron 43:527-37. 2004

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Illumination of the melanopsin signaling pathway
    Satchidananda Panda
    Genomics Institute of Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 307:600-4. 2005
    ..Melanopsin therefore signals more like an invertebrate opsin than like a classical vertebrate rod-and-cone opsin...
  2. ncbi request reprint Multiple photopigments entrain the Mammalian circadian oscillator
    Satchidananda Panda
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Neuron 53:619-21. 2007
    ..Dkhissi-Benyahya et al. demonstrate that medium wavelength opsin (MW-opsin) also plays an important role in the process. Furthermore, they develop a model explaining wavelength-dependent photoentrainment by melanopsin and MW-opsin...
  3. ncbi request reprint Melanopsin is required for non-image-forming photic responses in blind mice
    Satchidananda Panda
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 301:525-7. 2003
    ..This indicates the importance of both nonvisual and classical visual photoreceptor systems for nonvisual photic responses in mammals...
  4. pmc Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock
    Luciano DiTacchio
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Science 333:1881-5. 2011
    ..Drosophila lines with reduced expression of the Jarid1a homolog, lid, had lowered Per expression and similarly altered circadian rhythms. JARID1a thus has a nonredundant role in circadian oscillator function...
  5. ncbi request reprint Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting
    Satchidananda Panda
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 298:2213-6. 2002
    ..However, they display severely attenuated phase resetting in response to brief pulses of monochromatic light, highlighting the critical role of melanopsin in circadian photoentrainment in mammals...
  6. pmc Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
    Megumi Hatori
    Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Cell Metab 15:848-60. 2012
    ..We demonstrate in mice that tRF regimen is a nonpharmacological strategy against obesity and associated diseases...
  7. pmc Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines
    Rajesh Narasimamurthy
    Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 109:12662-7. 2012
    ..These results offer a mechanistic framework for understanding the link between circadian rhythm disruption and increased susceptibility to chronic inflammatory diseases...
  8. ncbi request reprint Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior
    M Fernanda Ceriani
    Institute of Childhood and Neglected Diseases, Department of Cell Biology ICND216, The Scripps Research Institute, La Jolla, California 92037, USA
    J Neurosci 22:9305-19. 2002
    ..Finally, taking full advantage of the fly as a model system, we have identified and characterized a cycling potassium channel protein as a key step in linking the transcriptional feedback loop to rhythmic locomotor behavior...
  9. pmc Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
    Christopher Vollmers
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 106:21453-8. 2009
    ..Our findings show that both temporal pattern of food intake and the circadian clock drive rhythmic transcription, thereby highlighting temporal regulation of hepatic transcription as an emergent property of the circadian system...
  10. ncbi request reprint A functional genomics strategy reveals Rora as a component of the mammalian circadian clock
    Trey K Sato
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, California 92121, USA
    Neuron 43:527-37. 2004
    ..These results suggest that opposing activities of the orphan nuclear receptors Rora and Rev-erb alpha, which represses Bmal1 expression, are important in the maintenance of circadian clock function...
  11. ncbi request reprint Circadian light input in plants, flies and mammals
    Satchidananda Panda
    Department of Cell Biology, The Scripps Research Foundation, 10550, North Torrey Pines Road, La Jolla, CA 92037, USA
    Novartis Found Symp 253:73-82; discussion 82-8, 102-9, 281-4. 2003
    ..They have also devised multiple photoreceptors and signalling cascades to buffer against changes in the spectral composition of natural light. The interaction of the clock with ambient light is, therefore, quite intricate...
  12. ncbi request reprint Circadian transcriptional output in the SCN and liver of the mouse
    John B Hogenesch
    The Genomics Institute, Novartis Research Foundation, San Diego, CA 9212, USA
    Novartis Found Symp 253:171-80; discussion 52-5, 102-9, 180-3 passim. 2003
    ..This wealth of circadian outputs offers exciting challenges to deciphering systems-level transcriptional regulatory mechanisms that underlie spatiotemporal gene expression...
  13. pmc Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
    Han Cho
    Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Nature 485:123-7. 2012
    ....
  14. ncbi request reprint DNA arrays: applications and implications for circadian biology
    Trey K Sato
    The Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
    J Biol Rhythms 18:96-105. 2003
    ..Here, we review the underlying technology behind DNA arrays, discuss general applications, and focus on the use of the arrays in the study of circadian biology in plants, flies, and mice...
  15. pmc Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock
    Sandhya R Pulivarthy
    Regulatory Biology Laboratory and Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 104:20356-61. 2007
    ..Real-time monitoring of PER2 oscillations in single cells reveals that changes in both synchrony and amplitude of individual oscillators underlie these phenomena...
  16. ncbi request reprint Coordinated transcription of key pathways in the mouse by the circadian clock
    Satchidananda Panda
    The Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA
    Cell 109:307-20. 2002
    ..Importantly, rate-limiting steps in these various pathways were key sites of circadian control, highlighting the fundamental role that circadian clocks play in cellular and organismal physiology...
  17. pmc Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6
    Daniel D Clark
    Department of Reproductive Medicine, University of California, San Diego, La Jolla, CA, USA
    J Biol Rhythms 28:15-25. 2013
    ..Therefore, Six6 is required for the normal development of the SCN, and the Six6-null mouse can mount independent, although irregular, circadian rhythms despite the apparent absence of a histochemically defined SCN...
  18. pmc Circadian oscillations of protein-coding and regulatory RNAs in a highly dynamic mammalian liver epigenome
    Christopher Vollmers
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Cell Metab 16:833-45. 2012
    ..The results offer a framework for understanding the dynamics of metabolism, circadian clock, and chromatin modifications involved in metabolic homeostasis...
  19. ncbi request reprint An array of insights: application of DNA chip technology in the study of cell biology
    Satchidananda Panda
    The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Trends Cell Biol 13:151-6. 2003
    ..Concomitant with the expanding ability of the technology has been the development of novel techniques and their application towards the study of cellular biology...
  20. pmc AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
    Katja A Lamia
    Gene Expression Laboratory, The Salk Institute, La Jolla, CA 92037, USA
    Science 326:437-40. 2009
    ..Thus, phosphorylation by AMPK enables cryptochrome to transduce nutrient signals to circadian clocks in mammalian peripheral organs...
  21. ncbi request reprint tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator
    Satchidananda Panda
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Dev Cell 3:51-61. 2002
    ..Posttranslational poly(ADP-ribosyl)ation of an oscillator component may contribute to setting the period length of the Arabidopsis central oscillator...
  22. ncbi request reprint Systems biology of circadian rhythms: an outlook
    Luciano De Haro
    The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    J Biol Rhythms 21:507-18. 2006
    ..In this review, the authors discuss the potential application of these genome-wide approaches in the study of circadian rhythms...
  23. pmc The emerging roles of melanopsin in behavioral adaptation to light
    Megumi Hatori
    The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Trends Mol Med 16:435-46. 2010
    ..These findings now offer new avenues to understand the role of ambient light in sleep, alertness, dependent physiologies and potential pharmacological intervention as well as lifestyle modifications to improve the quality of life...
  24. ncbi request reprint Circadian rhythms from flies to human
    Satchidananda Panda
    Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    Nature 417:329-35. 2002
    ..To gain the initial insights into circadian mechanisms, researchers turned to genetically tractable model organisms such as Drosophila...
  25. pmc A high-throughput assay for siRNA-based circadian screens in human U2OS cells
    Christopher Vollmers
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 3:e3457. 2008
    ....
  26. pmc Feeding mistiming decreases reproductive fitness in flies
    Shubhroz Gill
    Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Cell Metab 13:613-4. 2011
    ..Feeding the flies in the evening uncouples their metabolic cycle from circadian activity rhythms. A paper by Xu et al. in this issue of Cell Metabolism found that such uncoupled rhythms reduce egg laying...
  27. pmc Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses
    Megumi Hatori
    The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 3:e2451. 2008
    ....
  28. ncbi request reprint It's all in the timing: many clocks, many outputs
    Satchidananda Panda
    Genomics Institute of Novartis Research Foundation
    J Biol Rhythms 19:374-87. 2004
    ..Recent technology has improved our understanding of these processes, elucidating the anatomic outputs of the SCN, as well as the molecular outputs of both central and peripheral oscillators that mediate observed physiological changes...
  29. pmc BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
    R Daniel Rudic
    Center for Experimental Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    PLoS Biol 2:e377. 2004
    ..Furthermore, asynchronous dietary cues may modify glucose homeostasis via their interactions with peripheral molecular clocks...
  30. ncbi request reprint The transcriptional repressor STRA13 regulates a subset of peripheral circadian outputs
    Aline Grechez-Cassiau
    Universite de Nice Sophia Antipolis, CNRS UMR 6078, La Darse, 06230 Villefranche Mer, France
    J Biol Chem 279:1141-50. 2004
    ..These biochemical and genetic data establish a role for the basic helix-loop-helix repressor STRA13 as a circadian output regulator in the periphery...
  31. pmc Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation
    Brooke H Miller
    Department of Neurobiology and Physiology, and Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA
    Proc Natl Acad Sci U S A 104:3342-7. 2007
    ....
  32. ncbi request reprint Bioinformatic analysis of circadian gene oscillation in mouse aorta
    R Daniel Rudic
    The Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA
    Circulation 112:2716-24. 2005
    ..Here, we undertake studies to globally assess circadian gene expression in murine aorta...