Jan Marc Orenstein

Summary

Affiliation: The George Washington University
Country: USA

Publications

  1. ncbi request reprint Isn't a picture still worth a thousand words?
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 24:67-74. 2000
  2. ncbi request reprint The Warthin-Finkeldey-type giant cell in HIV infection, what is it?
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC, USA
    Ultrastruct Pathol 22:293-303. 1998
  3. ncbi request reprint Ultrastructure of HIV/AIDS
    Jan Marc Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 26:245-50. 2002
  4. ncbi request reprint The histopathology of 103 consecutive colonoscopy biopsies from 82 symptomatic patients with acquired immunodeficiency syndrome: original and look-back diagnoses
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, 2300 Eye Street NW, Washington, DC 20037, USA
    Arch Pathol Lab Med 125:1042-6. 2001
  5. ncbi request reprint Morphogenesis of HHV8 in primary human dermal microvascular endothelium and primary effusion lymphomas
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC 20037, USA
    Ultrastruct Pathol 24:291-300. 2000
  6. ncbi request reprint Rapid activation of lymph nodes and mononuclear cell HIV expression upon interrupting highly active antiretroviral therapy in patients after prolonged viral suppression
    J M Orenstein
    Department of Pathology, George Washington University Hospital, Washington, DC, USA
    AIDS 14:1709-15. 2000
  7. ncbi request reprint In vivo cytolysis and fusion of human immunodeficiency virus type 1-infected lymphocytes in lymphoid tissue
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    J Infect Dis 182:338-42. 2000
  8. ncbi request reprint Human endogenous retroviral expression by leukocytes
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC 20037, USA
    Ultrastruct Pathol 24:123-4. 2000
  9. ncbi request reprint Lymph node architecture preceding and following 6 months of potent antiviral therapy: follicular hyperplasia persists in parallel with p24 antigen restoration after involution and CD4 cell depletion in an AIDS patient
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    AIDS 13:2219-29. 1999
  10. ncbi request reprint The macrophage origin of the HIV-expressing multinucleated giant cells in hyperplastic tonsils and adenoids
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 23:79-91. 1999

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Isn't a picture still worth a thousand words?
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 24:67-74. 2000
    ..g., lysosome and Golgi vesicles. It is important to review the subject periodically to maintain its quality...
  2. ncbi request reprint The Warthin-Finkeldey-type giant cell in HIV infection, what is it?
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC, USA
    Ultrastruct Pathol 22:293-303. 1998
    ..TEM and ISH revealed evidence of HIV expression by FDC, but not WFTGC. WFTGC in HIV- lymphoid specimens displayed identical LM and IHC characteristics. The WFTGC in HIV infection appears to represent a multinucleated form of FDC...
  3. ncbi request reprint Ultrastructure of HIV/AIDS
    Jan Marc Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 26:245-50. 2002
    ....
  4. ncbi request reprint The histopathology of 103 consecutive colonoscopy biopsies from 82 symptomatic patients with acquired immunodeficiency syndrome: original and look-back diagnoses
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, 2300 Eye Street NW, Washington, DC 20037, USA
    Arch Pathol Lab Med 125:1042-6. 2001
    ....
  5. ncbi request reprint Morphogenesis of HHV8 in primary human dermal microvascular endothelium and primary effusion lymphomas
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC 20037, USA
    Ultrastruct Pathol 24:291-300. 2000
    ..It appears that HHV8 propagate in DMVEC, with and without stimulation, and have a similar morphogenesis to that seen in PEL cell lines and Kaposi sarcoma lesions. Several unique features characterize cells productively infected by HHV8...
  6. ncbi request reprint Rapid activation of lymph nodes and mononuclear cell HIV expression upon interrupting highly active antiretroviral therapy in patients after prolonged viral suppression
    J M Orenstein
    Department of Pathology, George Washington University Hospital, Washington, DC, USA
    AIDS 14:1709-15. 2000
    ....
  7. ncbi request reprint In vivo cytolysis and fusion of human immunodeficiency virus type 1-infected lymphocytes in lymphoid tissue
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    J Infect Dis 182:338-42. 2000
    ..Thus, HIV-positive lymphocytes undergo lysis in lymphoid tissue. The cellular debris is phagocytized by macrophages, which themselves can replicate HIV. HIV-positive lymphocytes fuse in lymph nodes to form multinucleated cells...
  8. ncbi request reprint Human endogenous retroviral expression by leukocytes
    J M Orenstein
    Department of Pathology, George Washington University, Washington, DC 20037, USA
    Ultrastruct Pathol 24:123-4. 2000
    ..Budding endogenous retroviral particles were identified on the plasma membrane of a high percentage of neurotrophils in four widely varied pathological specimens...
  9. ncbi request reprint Lymph node architecture preceding and following 6 months of potent antiviral therapy: follicular hyperplasia persists in parallel with p24 antigen restoration after involution and CD4 cell depletion in an AIDS patient
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    AIDS 13:2219-29. 1999
    ..To evaluate changes in architecture, viral RNA, and viral protein over 6 months in lymph nodes from retroviral-naïve HIV-infected persons before and after commencing highly active antiretroviral therapy (HAART)...
  10. ncbi request reprint The macrophage origin of the HIV-expressing multinucleated giant cells in hyperplastic tonsils and adenoids
    J M Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 23:79-91. 1999
    ....
  11. doi request reprint Hyperplastic lymphoid tissue in HIV/AIDS: an electron microscopic study
    Jan Marc Orenstein
    Department ofPathology, George Washington University Medical Center, Washington, DC 20037, USA
    Ultrastruct Pathol 32:161-9. 2008
    ..Ultrastructural study graphically demonstrated the abundance of HIV particles associated with the complex FDC network of hyperplastic lymph nodes, tonsils, and GALT. HIV was shown to productively infect FDC, as well as lymphocytes...
  12. doi request reprint Opportunistic disorders of the gastrointestinal tract in the age of highly active antiretroviral therapy
    Alison R Huppmann
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037, USA
    Hum Pathol 41:1777-87. 2010
    ..Thus, where HIV/AIDS is common, it is important to be able to diagnose these GI processes. In addition to presenting post-HAART incidences, diagnostic features and aids are described for selected entities...
  13. pmc Three linked vasculopathic processes characterize Kawasaki disease: a light and transmission electron microscopic study
    Jan Marc Orenstein
    Department of Pathology, George Washington University School of Medicine, Washington, District of Columbia, USA
    PLoS ONE 7:e38998. 2012
    ..Pathologic studies proposing an acute coronary arteritis followed by healing fail to account for the complex vasculopathy and clinical course...
  14. doi request reprint Ultrastructure of Kaposi sarcoma
    Jan Marc Orenstein
    Department of Pathology, George Washington University, Washington DC 20037, USA
    Ultrastruct Pathol 32:211-20. 2008
    ..The final stages of RBC disintegration were hemosiderin and ferritin. Most significantly, this study disclosed that KS is actually composed of a single type of randomly oriented spindle cell forming vessels of varying size and integrity...
  15. ncbi request reprint Replication of HIV-1 in vivo and in vitro
    Jan Marc Orenstein
    Department of Pathology, George Washington University Medical Center, Washington, DC 20037 2336, USA
    Ultrastruct Pathol 31:151-67. 2007
    ..It is shown that while HIV is regularly found in LE/MVB in vitro, it is infrequently the case in vivo. Therefore, the results challenge the "Trojan horse" concept...
  16. pmc PPEY motif within the rabies virus (RV) matrix protein is essential for efficient virion release and RV pathogenicity
    Christoph Wirblich
    Department of Microbiology and Immunology, Thomas Jefferson University, 531 BLSB, 233 South 10th St, Philadelphia, PA 19107, USA
    J Virol 82:9730-8. 2008
    ..Our data indicate that the RV PPEY motif has L-domain activity essential for efficient virus production and pathogenicity but is not essential for immunogenicity and thus can be targeted to increase the safety of rabies vaccine vectors...