Affiliation: The Methodist Hospital
- Absence of IDH1-R132H mutation predicts rapid progression of nonenhancing diffuse glioma in older adultsAdriana Olar
Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, TX, USA
Ann Diagn Pathol 16:161-70. 2012..The shorter interval of progression and negative IDH1-R132H mutation status suggest a similar molecular pathway as seen in primary GBM...
- Biomarkers classification and therapeutic decision-making for malignant gliomasAdriana Olar
Department of Pathology and Genomic Medicine, The Methodist Hospital, 6565 Fannin St, M227, Houston, TX 77030, USA
Curr Treat Options Oncol 13:417-36. 2012....
- Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric gliomaAditya Raghunathan
Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
Ann Diagn Pathol 16:255-9. 2012..The absence of mutant IDH1 R132H protein expression in AG may help further distinguish this unique neoplasm from diffuse glioma...
- Using the molecular classification of glioblastoma to inform personalized treatmentAdriana Olar
Department of Pathology, University of Texas MD Anderson Cancer Centre, Houston, TX, USA
J Pathol 232:165-77. 2014..In this paper we review basic glioblastoma pathophysiology, with emphasis on clinically relevant genetic molecular alterations and potential targets for further drug development...