JAMES M O'BRIEN

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Sepsis
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Medical Center, Columbus 43210, USA
    Am J Med 120:1012-22. 2007
  2. doi request reprint The association between body mass index, processes of care, and outcomes from mechanical ventilation: a prospective cohort study
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, College of Public Health, The Ohio State University, Columbus, OH, USA
    Crit Care Med 40:1456-63. 2012
  3. doi request reprint Will performance measurement lead to better patient outcomes? What are the roles of the National Quality Forum and Medical Specialty Societies?
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, Ohio State University Medical Center, Columbus, OH 43210, USA
    Chest 141:300-7. 2012
  4. pmc Delta inflation: a bias in the design of randomized controlled trials in critical care medicine
    Scott K Aberegg
    Department of Critical Care, Jordan Valley Medical Center, 3580 West 9000 South, West Jordan, Utah 84088, USA
    Crit Care 14:R77. 2010
  5. pmc Results from the National Sepsis Practice Survey: use of drotrecogin α (activated) and other therapeutic decisions
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA
    J Crit Care 25:658.e7-15. 2010
  6. pmc Year in review 2007: Critical Care--multiple organ failure and sepsis
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, 201 Davis HLRI, 473 West 12th Avenue, Columbus, OH 43210, USA
    Crit Care 12:228. 2008
  7. pmc Insurance type and sepsis-associated hospitalizations and sepsis-associated mortality among US adults: a retrospective cohort study
    JAMES M O'BRIEN
    Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, Columbus, OH 43221, USA
    Crit Care 15:R130. 2011
  8. pmc Results from the national sepsis practice survey: predictions about mortality and morbidity and recommendations for limitation of care orders
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Crit Care 13:R96. 2009
  9. pmc Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Medical Center, Columbus, USA
    Crit Care Med 34:738-44. 2006
  10. doi request reprint Acquired weakness, handgrip strength, and mortality in critically ill patients
    Naeem A Ali
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, 473 W 12th Avenue, Columbus, OH 43221, USA
    Am J Respir Crit Care Med 178:261-8. 2008

Research Grants

Detail Information

Publications21

  1. ncbi request reprint Sepsis
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Medical Center, Columbus 43210, USA
    Am J Med 120:1012-22. 2007
    ..Better description of the molecular basis of the disease process also will allow for more targeted therapies...
  2. doi request reprint The association between body mass index, processes of care, and outcomes from mechanical ventilation: a prospective cohort study
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, College of Public Health, The Ohio State University, Columbus, OH, USA
    Crit Care Med 40:1456-63. 2012
    ..To determine the association between excess weight and processes of care and outcomes for critically ill adults...
  3. doi request reprint Will performance measurement lead to better patient outcomes? What are the roles of the National Quality Forum and Medical Specialty Societies?
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, Ohio State University Medical Center, Columbus, OH 43210, USA
    Chest 141:300-7. 2012
    ....
  4. pmc Delta inflation: a bias in the design of randomized controlled trials in critical care medicine
    Scott K Aberegg
    Department of Critical Care, Jordan Valley Medical Center, 3580 West 9000 South, West Jordan, Utah 84088, USA
    Crit Care 14:R77. 2010
    ..The reasons for this are unknown...
  5. pmc Results from the National Sepsis Practice Survey: use of drotrecogin α (activated) and other therapeutic decisions
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA
    J Crit Care 25:658.e7-15. 2010
    ..We sought to evaluate factors associated with choices about provided care for patients with septic shock, including the use of drotrecogin α (activated) (DAA)...
  6. pmc Year in review 2007: Critical Care--multiple organ failure and sepsis
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, 201 Davis HLRI, 473 West 12th Avenue, Columbus, OH 43210, USA
    Crit Care 12:228. 2008
    ..The present review summarizes the findings and implications of the papers published on sepsis and multiorgan failure and places the research in the context of other work in the field...
  7. pmc Insurance type and sepsis-associated hospitalizations and sepsis-associated mortality among US adults: a retrospective cohort study
    JAMES M O'BRIEN
    Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, Columbus, OH 43221, USA
    Crit Care 15:R130. 2011
    ..We hypothesized that patients with Medicare and/or Medicaid or without health insurance have a higher risk of sepsis-associated hospitalization or sepsis-associated death than those with private health insurance...
  8. pmc Results from the national sepsis practice survey: predictions about mortality and morbidity and recommendations for limitation of care orders
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Crit Care 13:R96. 2009
    ..Little is known about patient and clinician factors which influence these predictions. The association between these predictions and recommendations for continued aggressive care is also understudied...
  9. pmc Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury
    JAMES M O'BRIEN
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Medical Center, Columbus, USA
    Crit Care Med 34:738-44. 2006
    ..To determine the association between body mass index (BMI) and hospital mortality for critically ill adults...
  10. doi request reprint Acquired weakness, handgrip strength, and mortality in critically ill patients
    Naeem A Ali
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, 473 W 12th Avenue, Columbus, OH 43221, USA
    Am J Respir Crit Care Med 178:261-8. 2008
    ..However, it is unclear whether ICUAP is independently associated with mortality, as sicker patients are more prone and existing studies have not adjusted for this...
  11. pmc Glucose variability and mortality in patients with sepsis
    Naeem A Ali
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine and Center for Critical Care, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio, USA
    Crit Care Med 36:2316-21. 2008
    ..Our objective was to determine the association between glucose variability and hospital mortality in septic patients and the expression of glucose variability that best reflects this risk...
  12. pmc Year in review in Critical Care, 2004: sepsis and multi-organ failure
    JAMES M O'BRIEN
    Division of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University Medical Center, Columbus, Ohio, USA
    Crit Care 9:409-13. 2005
  13. doi request reprint Continuity of care in intensive care units: a cluster-randomized trial of intensivist staffing
    Naeem A Ali
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Indiana University, Indianapolis, Indiana, USA
    Am J Respir Crit Care Med 184:803-8. 2011
    ..Little is known about the consequences of intensivists’ work schedules, or intensivist continuity of care...
  14. doi request reprint Factors associated with elevated plateau pressure in patients with acute lung injury receiving lower tidal volume ventilation
    Hallie C Prescott
    Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH, USA
    Crit Care Med 41:756-64. 2013
    ....
  15. ncbi request reprint Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality
    Naeem A Ali
    Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Ohio State University, Columbus, Ohio 43210, USA
    Cancer 110:96-102. 2007
    ..The authors hypothesized that hyperglycemia may be associated with adverse outcomes in patients with acute myeloid leukemia (AML) and sought to determine whether this association exists in this population...
  16. doi request reprint The normalization heuristic: an untested hypothesis that may misguide medical decisions
    Scott K Aberegg
    The Ohio State University College of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, 201 Davis Heart Lung Research Institute, 473 West 12th Avenue, Columbus, Ohio 43210, USA
    Med Hypotheses 72:745-8. 2009
    ..We review historical and contemporaneous examples of normalization practices as empirical evidence for the normalization heuristic and to highlight its frailty as a guide for clinical decision making...
  17. pmc Obesity and acute lung injury
    Jennifer W McCallister
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Center for Critical Care, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Clin Chest Med 30:495-508, viii. 2009
    ..The few studies that have examined the influence of obesity on the outcomes from ALI/ARDS are inconclusive. Furthermore, observed results could be biased by disparities in provided care...
  18. pmc Extended-infusion cefepime reduces mortality in patients with Pseudomonas aeruginosa infections
    Karri A Bauer
    Department of Pharmacy, The Ohio State University Medical Center, Columbus, Ohio, USA
    Antimicrob Agents Chemother 57:2907-12. 2013
    ..13). We conclude that extended-infusion treatment with cefepime provides increased clinical and economic benefits in the treatment of invasive P. aeruginosa infections...
  19. doi request reprint Clinical problem-solving. Failure to respond--a 52-year-old man presented to his primary care physician with dyspnea and cough
    Michael E Ezzie
    Department of Medicine, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Ohio State University, Columbus, OH 43210, USA
    N Engl J Med 358:70-4. 2008
  20. doi request reprint Does value-based purchasing enhance quality of care and patient outcomes in the ICU?
    JAMES M O'BRIEN
    Quality and Patient Safety, Riverside Methodist Hospital, Columbus, OH 43214, USA
    Crit Care Clin 29:91-112. 2013
    ..Rising health care costs, however, make VBP an attractive approach for curtailing costs and emphasizing improved quality, and VBP is likely to become a more prevalent mechanism of reimbursement for providers and facilities...
  21. doi request reprint The search-inference framework: a proposed strategy for novice clinical problem solving
    Scott K Aberegg
    The Ohio State University College of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Columbus, Ohio, USA
    Med Educ 42:389-95. 2008
    ..Before novice problem solvers develop these illness scripts, pattern recognition may not be effective for solving clinical problems...

Research Grants2

  1. The Obese Critical III: Process and Outcome Disparities
    James O Brien; Fiscal Year: 2007
    ..These studies will describe the effect of excess body weight on critical illness and produce a new type of independent investigator - the ICU health services researcher. ..