Robin E Norris

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. doi request reprint Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias
    Robin E Norris
    Division of Clinical Pharmacology and Therapeutics, Children s Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd, Suite 916, Philadelphia, PA 19104, USA
    Cancer Chemother Pharmacol 65:1125-30. 2010
  2. doi request reprint Preclinical evaluation of lestaurtinib (CEP-701) in combination with retinoids for neuroblastoma
    Robin E Norris
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Cancer Chemother Pharmacol 68:1469-75. 2011
  3. doi request reprint Preclinical evaluation of pemetrexed in pediatric solid tumors
    Robin E Norris
    Division of Clinical Pharmacology and Therapeutics, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 57:1233-5. 2011
  4. pmc Preclinical evaluation of the PARP inhibitor, olaparib, in combination with cytotoxic chemotherapy in pediatric solid tumors
    Robin E Norris
    Division of Pediatric Hematology Oncology, Rainbow Babies and Children s Hospital, Cleveland, Ohio Division of Clinical Pharmacology and Therapeutics, Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:145-50. 2014
  5. pmc Evaluation of the retinoids with Cisplatin and vincristine in xenograft models of neuroblastoma
    Robin E Norris
    Divison of Pediatric Hematology Oncology, Rainbow Babies and Children s Hospital, Cleveland, OH Division of Clinical Pharmacology and Therapeutics, Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA
    J Pediatr Hematol Oncol 36:e23-7. 2014

Detail Information

Publications5

  1. doi request reprint Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias
    Robin E Norris
    Division of Clinical Pharmacology and Therapeutics, Children s Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd, Suite 916, Philadelphia, PA 19104, USA
    Cancer Chemother Pharmacol 65:1125-30. 2010
    ..In this pre-clinical study we evaluated the in vitro activity of both traditional antifols (methotrexate, aminopterin) and novel antifols (pemetrexed, talotrexin) in childhood acute leukemias and lymphomas...
  2. doi request reprint Preclinical evaluation of lestaurtinib (CEP-701) in combination with retinoids for neuroblastoma
    Robin E Norris
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Cancer Chemother Pharmacol 68:1469-75. 2011
    ..We studied the interaction of CEP-701 with isotretinoin (13cRA) and fenretinide (4HPR), two retinoids that have been studied in children with high-risk neuroblastoma...
  3. doi request reprint Preclinical evaluation of pemetrexed in pediatric solid tumors
    Robin E Norris
    Division of Clinical Pharmacology and Therapeutics, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 57:1233-5. 2011
    ..Expression of folate pathway genes (DHFR, TS, GARFT, GGH) did not correlate with in vitro drug sensitivity. Further evaluation of pemetrexed for the treatment of ES is warranted...
  4. pmc Preclinical evaluation of the PARP inhibitor, olaparib, in combination with cytotoxic chemotherapy in pediatric solid tumors
    Robin E Norris
    Division of Pediatric Hematology Oncology, Rainbow Babies and Children s Hospital, Cleveland, Ohio Division of Clinical Pharmacology and Therapeutics, Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:145-50. 2014
    ..We evaluated the PARP inhibitor, olaparib, in combination with chemotherapy using in vitro and in vivo pediatric solid tumor models...
  5. pmc Evaluation of the retinoids with Cisplatin and vincristine in xenograft models of neuroblastoma
    Robin E Norris
    Divison of Pediatric Hematology Oncology, Rainbow Babies and Children s Hospital, Cleveland, OH Division of Clinical Pharmacology and Therapeutics, Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA
    J Pediatr Hematol Oncol 36:e23-7. 2014
    ..Concomitant administration of isotretinoin or fenretinide with the cytotoxic agents did not result in any clear potentiation of cytotoxicity. ..