Frances Noonan

Summary

Affiliation: The George Washington University
Country: USA

Publications

  1. ncbi request reprint Animal models of melanoma: an HGF/SF transgenic mouse model may facilitate experimental access to UV initiating events
    Frances P Noonan
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University School of Medicine, Washington, DC, USA
    Pigment Cell Res 16:16-25. 2003
  2. doi request reprint UVB and UVA initiate different pathways to p53-dependent apoptosis in melanocytes
    Frances P Noonan
    Department of Microbiology, Immunology, and Tropical Medicine, George Washington University Medical Center, Washington, DC 20037, USA
    J Invest Dermatol 129:1608-10. 2009
  3. ncbi request reprint Mice with genetically determined high susceptibility to ultraviolet (UV)-induced immunosuppression show enhanced UV carcinogenesis
    Frances P Noonan
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, Washington, DC 20037, USA
    J Invest Dermatol 121:1175-81. 2003
  4. pmc Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin
    Agnieszka Wolnicka-Glubisz
    Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University Medical Center, Washington, DC, USA
    Exp Dermatol 22:226-8. 2013
  5. ncbi request reprint Deficient inflammatory response to UV radiation in neonatal mice
    Agnieszka Wolnicka-Glubisz
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, George Washington University Medical Center, Ross Hall, 2300 Eye Street, N W, Washington, DC 20037, USA
    J Leukoc Biol 81:1352-61. 2007
  6. ncbi request reprint Neonatal susceptibility to UV induced cutaneous malignant melanoma in a mouse model
    Agnieszka Wolnicka-Glubisz
    Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, 2300 Eye Street, NW, Ross Hall, Rm 110, Washington DC 20037, USA
    Photochem Photobiol Sci 5:254-60. 2006
  7. ncbi request reprint Animal models of melanoma
    Linan Ha
    Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, Bethesda, Maryland 20892, USA
    J Investig Dermatol Symp Proc 10:86-8. 2005
  8. ncbi request reprint Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis
    Juan A Recio
    Laboratory of Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892 4264, USA
    Cancer Res 62:6724-30. 2002
  9. ncbi request reprint Ultraviolet B but not ultraviolet A radiation initiates melanoma
    Edward C De Fabo
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, Washington, DC 20037, USA
    Cancer Res 64:6372-6. 2004
  10. ncbi request reprint Ultraviolet radiation and cutaneous malignant melanoma
    Chamelli Jhappan
    Molecular Genetics Section, Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892 4264, USA
    Oncogene 22:3099-112. 2003

Research Grants

  1. STRAIN DIFFERENCES IN UVB SUPPRESSION
    Frances Noonan; Fiscal Year: 1993
  2. A mouse model for UV-induced junctional melanoma
    Frances Noonan; Fiscal Year: 2006

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Animal models of melanoma: an HGF/SF transgenic mouse model may facilitate experimental access to UV initiating events
    Frances P Noonan
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University School of Medicine, Washington, DC, USA
    Pigment Cell Res 16:16-25. 2003
    ....
  2. doi request reprint UVB and UVA initiate different pathways to p53-dependent apoptosis in melanocytes
    Frances P Noonan
    Department of Microbiology, Immunology, and Tropical Medicine, George Washington University Medical Center, Washington, DC 20037, USA
    J Invest Dermatol 129:1608-10. 2009
    ..Sunlight exposure is a major risk factor for melanoma. In this issue, Waster and llinger investigate the effects of UVB and UVA on melanocytes...
  3. ncbi request reprint Mice with genetically determined high susceptibility to ultraviolet (UV)-induced immunosuppression show enhanced UV carcinogenesis
    Frances P Noonan
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, Washington, DC 20037, USA
    J Invest Dermatol 121:1175-81. 2003
    ..025). These findings support the concept that genetic differences in susceptibility to UV-induced immunosuppression may be a risk factor for skin cancer...
  4. pmc Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin
    Agnieszka Wolnicka-Glubisz
    Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University Medical Center, Washington, DC, USA
    Exp Dermatol 22:226-8. 2013
    ..We conclude that the absence of Mc1r does not impair the inflammatory response to UV radiation or the generation of immunosuppression...
  5. ncbi request reprint Deficient inflammatory response to UV radiation in neonatal mice
    Agnieszka Wolnicka-Glubisz
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, George Washington University Medical Center, Ross Hall, 2300 Eye Street, N W, Washington, DC 20037, USA
    J Leukoc Biol 81:1352-61. 2007
    ....
  6. ncbi request reprint Neonatal susceptibility to UV induced cutaneous malignant melanoma in a mouse model
    Agnieszka Wolnicka-Glubisz
    Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, 2300 Eye Street, NW, Ross Hall, Rm 110, Washington DC 20037, USA
    Photochem Photobiol Sci 5:254-60. 2006
    ....
  7. ncbi request reprint Animal models of melanoma
    Linan Ha
    Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, Bethesda, Maryland 20892, USA
    J Investig Dermatol Symp Proc 10:86-8. 2005
  8. ncbi request reprint Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis
    Juan A Recio
    Laboratory of Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892 4264, USA
    Cancer Res 62:6724-30. 2002
    ....
  9. ncbi request reprint Ultraviolet B but not ultraviolet A radiation initiates melanoma
    Edward C De Fabo
    Laboratory of Photobiology and Photoimmunology, Department of Environmental and Occupational Health, School of Public Health and Health Services, The George Washington University Medical Center, Washington, DC 20037, USA
    Cancer Res 64:6372-6. 2004
    ..Moreover, these differences in wavelength effectiveness can now be exploited to identify UV pathways relevant to melanomagenesis...
  10. ncbi request reprint Ultraviolet radiation and cutaneous malignant melanoma
    Chamelli Jhappan
    Molecular Genetics Section, Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892 4264, USA
    Oncogene 22:3099-112. 2003
    ..It is anticipated that exploitation of these model systems will contribute significantly toward the development of effective approaches to the prevention and treatment of melanoma...
  11. ncbi request reprint Modeling gene-environment interactions in malignant melanoma
    Glenn Merlino
    Laboratory of Molecular Biology, National Cancer Institute, Building 37, Room 5002, Bethesda, MD 20892 4264, USA
    Trends Mol Med 9:102-8. 2003
    ..These models are providing novel insights into how the genome and environment interact in vivo...
  12. ncbi request reprint SCA-1+ cells with an adipocyte phenotype in neonatal mouse skin
    Agnieszka Wolnicka-Glubisz
    J Invest Dermatol 125:383-5. 2005

Research Grants19

  1. STRAIN DIFFERENCES IN UVB SUPPRESSION
    Frances Noonan; Fiscal Year: 1993
    ..Establishing the existence of a gene(s) for enhanced susceptibility to UV suppression would provide a powerful tool for use in studies of UV carcinogenesis and of UV related autoimmune disease...
  2. A mouse model for UV-induced junctional melanoma
    Frances Noonan; Fiscal Year: 2006
    ..abstract_text> ..