Research Topics
| Kelly NicholsSummaryAffiliation: The Ohio State University Country: USA Publications
Research Grants
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Detail Information
Publications
Corneal staining in hydrogel lens wearersKelly K Nichols
Ohio State University College of Optometry, Columbus, Ohio, USA
Optom Vis Sci 79:20-30. 2002....
The reliability and validity of McMonnies Dry Eye IndexKelly K Nichols
Ohio State University College of Optometry, Columbus, OH 43218 2342, USA
Cornea 23:365-71. 2004..The purpose of this report was to investigate the psychometric properties of the McMonnies questionnaire for dry eye disease...
The relation between tear film tests in patients with dry eye diseaseKelly K Nichols
The Ohio State University, College of Optometry, 320 West 10th Avenue PO Box 182342, Columbus, OH 43218 2342, USA
Ophthalmic Physiol Opt 23:553-60. 2003..The purpose of this report was to investigate the relation between dry eye diagnostic tests...
The lack of association between signs and symptoms in patients with dry eye diseaseKelly K Nichols
College of Optometry, The Ohio State University, Columbus, OH 43218 2342, USA
Cornea 23:762-70. 2004..The purpose of this report was to examine the relation between clinical tests and dry eye symptoms in patients with dry eye disease...
Identification of fatty acids and fatty acid amides in human meibomian gland secretionsKelly K Nichols
College of Optometry, The Ohio State University, Columbus, OH 43210, USA
Invest Ophthalmol Vis Sci 48:34-9. 2007..Although classes of lipids found in the tear film have been reported, individual lipid species are currently being studied with more sophisticated...
Epinastine 0.05% ophthalmic solution in contact lens-wearing subjects with a history of allergic conjunctivitisKelly K Nichols
Ohio State University, College of Optometry, Columbus, OH 43210 1280, USA
Eye Contact Lens 35:26-31. 2009..To assess the comfort and efficacy of epinastine 0.05% ophthalmic solution in contact lens wearers with a history of allergic conjunctivitis and contact lens intolerance during allergy season...
The repeatability of clinical measurements of dry eyeKelly K Nichols
Ohio State University College of Optometry, Columbus, OH 43210, USA
Cornea 23:272-85. 2004..In this study, the repeatability of a battery of clinical diagnostic tests for dry eye was assessed on mild to moderate dry eye patients...
Investigation of the human tear film proteome using multiple proteomic approachesKari B Green-Church
Mass Spectrometry and Proteomics Facility, The Ohio State University, Columbus, OH 43210, USA
Mol Vis 14:456-70. 2008....
Contributions of evaporation and other mechanisms to tear film thinning and break-upP Ewen King-Smith
College of Optometry, The Ohio State University, 338 W 10th Avenue, Columbus, OH 43210, USA
Optom Vis Sci 85:623-30. 2008..Thus evaporation may be fast enough to explain many cases of tear film break-up, and to give rise to considerable increases in the local osmolarity of the tear film between blinks...
Patient-reported symptoms in dry dye diseaseKelly K Nichols
Ohio State University College of Optometry, Columbus, Ohio 43210 1280, USA
Ocul Surf 4:137-45. 2006..Common symptoms, available surveys, and the associations between diagnostic tests and symptoms are reviewed...
The contribution of lipid layer movement to tear film thinning and breakupP Ewen King-Smith
College of Optometry, Ohio State University, Columbus, Ohio, USA
Invest Ophthalmol Vis Sci 50:2747-56. 2009..To investigate whether the tear film thinning between blinks is caused by evaporation or by tangential flow of the tear film along the surface of the cornea. Tangential flow was studied by measuring the movement of the lipid layer...
Self-reported dry eye disease across refractive modalitiesJason J Nichols
Ohio State University, Columbus, 43218, USA
Invest Ophthalmol Vis Sci 46:1911-4. 2005..To compare self-reported dry eye disease across contact lens wearers, spectacles wearers, and clinical emmetropes (i.e., those not requiring refractive correction)...
Interferometric imaging of the full thickness of the precorneal tear filmP Ewen King-Smith
College of Optometry, The Ohio State University, 338 West 10th Avenue, Columbus, 43210, USA
J Opt Soc Am A Opt Image Sci Vis 23:2097-104. 2006..This method has the potential for evaluating the role of both tear film flow and evaporation in tear film thinning and breakup. It therefore may be applied to the analysis of dry eye disease...
An assessment of grading scales for meibography imagesJason J Nichols
The Ohio State University, Columbus, 43218, USA
Cornea 24:382-8. 2005..To evaluate the within- and between-reader reliability and the interrelation between 2 methods of grading meibography images...
An assessment of self-reported disease classification in epidemiological studies of dry eyeJason J Nichols
The Ohio State University, 320 West 10th Avenue, PO Box 182342, Columbus, OH 43218 2342, USA
Invest Ophthalmol Vis Sci 45:3453-7. 2004..To evaluate the reliability of self-reported dry eye disease status and patient-related predictors of misclassification in contact lens wearers...
The performance of the contact lens dry eye questionnaire as a screening survey for contact lens-related dry eyeJason J Nichols
Ohio State University College of Optometry, 320 West 10th Avenue, Rm 101, Columbus, OH 43210, USA
Cornea 21:469-75. 2002..In this report, we examine the CLDEQ as a screening survey for contact lens-related dry eye and compare it with McMonnies' questionnaire...
Evaluation of tear film interference patterns and measures of tear break-up timeJason J Nichols
The Ohio State University, College of Optometry, Columbus 43210, USA
Optom Vis Sci 79:363-9. 2002....
Gas permeable and soft contact lens wear in childrenLisa A Jones-Jordan
The Ohio State University College of Optometry, Columbus, Ohio 43210, USA
Optom Vis Sci 87:414-20. 2010..To compare children's reports of comfort, vision, and contact lens-related issues in gas permeable (GP) and soft (SCL) contact lens wearers...
The Contact Lens and Tear Film Laboratory, the Ohio State University College of OptometryKelly K Nichols
Ohio State University College of Optometry, Columbuc, OH, USA
Ocul Surf 5:259-61. 2007
Association of clinical diagnostic tests and dry eye surveys: the NEI-VFQ-25 and the OSDIKelly K Nichols
The Ohio State University College of Optometry, Columbus, Ohio, USA
Adv Exp Med Biol 506:1177-81. 2002
The repeatability of diagnostic tests and surveys in dry eyeKelly K Nichols
The Ohio State University College of Optometry, Columbus, Ohio, USA
Adv Exp Med Biol 506:1171-5. 2002
Patient-reported versus doctor-diagnosed dry eye: the assessment of symptomsG Lynn Mitchell
The Ohio State University College of Optometry, Columbus, Ohio, USA
Adv Exp Med Biol 506:1189-93. 2002
Diquafosol tetrasodium: a novel dry eye therapyKelly K Nichols
The Ohio State University, College of Optometry, Columbus, OH, USA
Expert Opin Investig Drugs 13:47-54. 2004..This review summarises key findings during development and in clinical trials including clinical effectiveness and safety. The relevance of P2Y2 receptor technology to dry eye disease and the disease process is discussed...
Performance and repeatability of the NEI-VFQ-25 in patients with dry eyeKelly K Nichols
Ohio State University College of Optometry, 320 West 10th Avenue, Columbus, OH 43210 1240, USA
Cornea 21:578-83. 2002..The purpose of this study was to assess the performance and test-retest repeatability of the 25-question format of the NEI-VFQ in patients with dry eye...
The frequency of dilated diabetic eye examinations by optometrists in the state of ohioBrian D Puent
University of Wisconsin Medical School, Department of Population Health Sciences, Madison, Wisconsin, USA
Optom Vis Sci 82:959-63. 2005..The purpose of this study was to assess optometric care of diabetic patients. The American Optometric Association recommends dilated eye examinations at least once a year for people with diabetes...
The changing times in dry eye researchKelly K Nichols
Optom Vis Sci 85:613-4. 2008
Current patterns in the use of diagnostic tests in dry eye evaluationJanine Smith
National Eye Institute NIH DHHS, Bethesda, MD, USA
Cornea 27:656-62. 2008..Dry eye signs and symptoms do not always correlate well, and there is currently some controversy over the ideal roles of signs and symptoms and their actual use in clinical practice...
The global sex disparity in blindness and visual impairmentDebra A Schaumberg
Optom Vis Sci 83:700-1. 2006
Research Grants
- Dry Eye in PostmenopauseKelly Nichols; Fiscal Year: 2007..This project is a unique blend of interdisciplinary clinical and basic research, which may lead to the translation of findings to clinical care in dry eye disease. ..
- Dry Eye in PostmenopauseKelly K Nichols; Fiscal Year: 2010..This project is a unique blend of interdisciplinary clinical and basic research, which may lead to the translation of findings to clinical care in dry eye disease. ..
