- Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53Jessica M Y Ng
Department of Pathology and Laboratory Medicine, Division of Cancer Pathobiology, The Children s Hospital of Philadelphia, Research Institute, Philadelphia, Pennsylvania
Cancer Res 75:4629-39. 2015..Our findings uncover a novel role for Snf5 in oligodendrocyte generation and survival, and they offer evidence of the first genetically engineered mouse model for AT/RT in the CNS...
- The Hedgehog's tale: developing strategies for targeting cancerJessica M Y Ng
Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia, 4060 Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia PA 19104, USA
Nat Rev Cancer 11:493-501. 2011..However, it remains unclear how many cancers will ultimately benefit from these new, molecularly targeted therapies...