Chaan S Ng

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi Reproducibility and comparison of DCE-MRI and DCE-CT perfusion parameters in a rat tumor model
    Chaan S Ng
    Department of Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Technol Cancer Res Treat 11:279-88. 2012
  2. doi Effect of duration of scan acquisition on CT perfusion parameter values in primary and metastatic tumors in the lung
    Chaan S Ng
    Departments of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
    Eur J Radiol 82:1811-8. 2013
  3. pmc Effect of sampling frequency on perfusion values in perfusion CT of lung tumors
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Unit 1473, 1400 Pressler St, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 200:W155-62. 2013
  4. pmc Effect of dual vascular input functions on CT perfusion parameter values and reproducibility in liver tumors and normal liver
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Comput Assist Tomogr 36:388-93. 2012
  5. doi Effect of IV contrast medium on renal function in oncologic patients undergoing CT in ICU
    Chaan S Ng
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4409, USA
    AJR Am J Roentgenol 195:414-22. 2010
  6. doi Reproducibility of perfusion parameters in dynamic contrast-enhanced MRI of lung and liver tumors: effect on estimates of patient sample size in clinical trials and on individual patient responses
    Chaan S Ng
    Department of Radiology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    AJR Am J Roentgenol 194:W134-40. 2010
  7. doi Perfusion CT in patients with metastatic renal cell carcinoma treated with interferon
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 368, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 194:166-71. 2010
  8. doi Tumor blood flow measured by perfusion computed tomography and 15O-labeled water positron emission tomography: a comparison study
    Chaan S Ng
    Department of Radiology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Comput Assist Tomogr 33:460-5. 2009
  9. ncbi Extracolonic findings in patients undergoing abdomino-pelvic CT for suspected colorectal carcinoma in the frail and disabled patient
    C S Ng
    Department of Radiology, Addenbrooke s NHS Trust and the University of Cambridge, Cambridge, UK
    Clin Radiol 59:421-30. 2004
  10. doi Renal cell carcinoma: diagnosis, staging, and surveillance
    Chaan S Ng
    Department of Radiology, Box 368, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 191:1220-32. 2008

Detail Information

Publications66

  1. ncbi Reproducibility and comparison of DCE-MRI and DCE-CT perfusion parameters in a rat tumor model
    Chaan S Ng
    Department of Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Technol Cancer Res Treat 11:279-88. 2012
    ..DCE-MRI and DCE-CT biomarkers of tumor perfusion have similar reproducibilities suggesting that they may have comparable utility, but their derived parameter values are not equivalent...
  2. doi Effect of duration of scan acquisition on CT perfusion parameter values in primary and metastatic tumors in the lung
    Chaan S Ng
    Departments of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
    Eur J Radiol 82:1811-8. 2013
    ..To assess the effect of acquisition duration (T(acq)) and pre-enhancement set points (T₁) on computer tomography perfusion (CT(p)) parameter values in primary and metastatic tumors in the lung...
  3. pmc Effect of sampling frequency on perfusion values in perfusion CT of lung tumors
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Unit 1473, 1400 Pressler St, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 200:W155-62. 2013
    ..The purpose of this study was to assess as a potential means of limiting radiation exposure the effect on perfusion CT values of increasing sampling intervals in lung perfusion CT acquisition...
  4. pmc Effect of dual vascular input functions on CT perfusion parameter values and reproducibility in liver tumors and normal liver
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Comput Assist Tomogr 36:388-93. 2012
    ..To assess the impact on absolute values and reproducibility of adding portal venous (PV) to arterial input functions in computed tomographic perfusion (CTp) evaluations of liver tumors and normal liver...
  5. doi Effect of IV contrast medium on renal function in oncologic patients undergoing CT in ICU
    Chaan S Ng
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4409, USA
    AJR Am J Roentgenol 195:414-22. 2010
    ....
  6. doi Reproducibility of perfusion parameters in dynamic contrast-enhanced MRI of lung and liver tumors: effect on estimates of patient sample size in clinical trials and on individual patient responses
    Chaan S Ng
    Department of Radiology, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    AJR Am J Roentgenol 194:W134-40. 2010
    ..Our aim was to determine the reproducibility of perfusion parameters derived at DCE-MRI of tumors of the lung and liver, the most common sites of metastasis...
  7. doi Perfusion CT in patients with metastatic renal cell carcinoma treated with interferon
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 368, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 194:166-71. 2010
    ....
  8. doi Tumor blood flow measured by perfusion computed tomography and 15O-labeled water positron emission tomography: a comparison study
    Chaan S Ng
    Department of Radiology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Comput Assist Tomogr 33:460-5. 2009
    ..To compare blood flow measurements of tumors assessed by perfusion computed tomography (pCT) and the clinical gold standard of 15O-labeled water positron emission tomography (15O-PET)...
  9. ncbi Extracolonic findings in patients undergoing abdomino-pelvic CT for suspected colorectal carcinoma in the frail and disabled patient
    C S Ng
    Department of Radiology, Addenbrooke s NHS Trust and the University of Cambridge, Cambridge, UK
    Clin Radiol 59:421-30. 2004
    ..The aims of this study were to evaluate the extracolonic findings identified in patients undergoing minimal preparation abdomino-pelvic CT in place of barium enema or colonoscopy for the detection of possible colorectal carcinoma...
  10. doi Renal cell carcinoma: diagnosis, staging, and surveillance
    Chaan S Ng
    Department of Radiology, Box 368, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 191:1220-32. 2008
    ..It includes discussion of the epidemiology, pathology, and therapeutic options of renal cell carcinoma and the implications for radiologic follow-up...
  11. doi Assessing diagnostic confidence: a comparative review of analytical methods
    Chaan S Ng
    Department of Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Acad Radiol 15:584-92. 2008
    ..The ability of a test to influence diagnostic confidence is used as a measure of its efficacy. Our aim was to compare analytic methods that evaluate changes in confidence...
  12. doi Minimal-preparation abdomino-pelvic CT in frail and elderly patients: prognostic value of colonic and extracolonic findings
    C S Ng
    Department of Radiology, University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Clin Radiol 63:424-32. 2008
    ..To examine the overall survival of patients who had had been referred for minimal preparation abdomino-pelvic computed tomography (MPCT), and to assess the prognostic value of the colonic and extracolonic findings detected...
  13. doi Perfusion CT findings in patients with metastatic carcinoid tumors undergoing bevacizumab and interferon therapy
    Chaan S Ng
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    AJR Am J Roentgenol 196:569-76. 2011
    ..The purpose of this article is to assess tumor changes on perfusion CT with bevacizumab and interferon (IFN) therapy in patients with metastatic carcinoid tumors and to evaluate perfusion CT differences between the two therapies...
  14. doi Analysis of diagnostic confidence: application to data from a prospective randomized controlled trial of CT for acute abdominal pain
    Chaan S Ng
    Department of Radiology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Acta Radiol 51:368-74. 2010
    ..Changes in diagnostic confidence are used as a measure of a test's efficacy. There are several methods for analyzing such data, but it is unclear which are most robust...
  15. doi Reproducibility of perfusion parameters obtained from perfusion CT in lung tumors
    Chaan S Ng
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4009, USA
    AJR Am J Roentgenol 197:113-21. 2011
    ..The purpose of this article is to assess the variability of perfusion CT measurements in lung tumors and the effects of motion and duration of data acquisition on perfusion CT parameter values...
  16. pmc Reproducibility of CT perfusion parameters in liver tumors and normal liver
    Chaan S Ng
    Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, 1400 Pressler St, Unit 1473, Houston, TX 77030 4009, USA
    Radiology 260:762-70. 2011
    ..To assess the reproducibility of computed tomographic (CT) perfusion measurements in liver tumors and normal liver and effects of motion and data acquisition time on parameters...
  17. ncbi Caecal carcinomas in the elderly: useful signs in minimal preparation CT
    C S Ng
    Department of Radiology, Addenbrooke s NHS Trust and the University of Cambridge, Cambridge, UK
    Clin Radiol 57:359-64. 2002
    ..The aims of this study were to evaluate the accuracy of a minimal preparation CT technique (merely with prolonged oral contrast medium) in identifying caecal carcinomas and to determine helpful radiological signs...
  18. ncbi Evaluation of CT in identifying colorectal carcinoma in the frail and disabled patient
    C S Ng
    Department of Radiology, Addenbrooke s NHS Trust, University of Cambridge, UK
    Eur Radiol 12:2988-97. 2002
    ..Although interpretation can be difficult, the technique is able to exclude malignancy with good accuracy...
  19. pmc Evaluation of early abdominopelvic computed tomography in patients with acute abdominal pain of unknown cause: prospective randomised study
    Chaan S Ng
    Department of Radiology, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ
    BMJ 325:1387. 2002
    ..To evaluate the impact of early abdominopelvic computed tomography in patients with acute abdominal pain of unknown cause on length of hospital stay and accuracy of diagnosis...
  20. pmc Phase II trial of pemetrexed plus gemcitabine in patients with locally advanced and metastatic nonclear cell renal cell carcinoma
    Stephen L Richey
    Departments of Genitourinary Medical Oncology Pathology Radiology Biostatistics, The University of Texas M D Anderson Cancer Center, Houston, TX
    Am J Clin Oncol 36:450-4. 2013
    ..To determine the clinical activity and safety of the combination of pemetrexed and gemcitabine in advanced nonclear cell renal cell carcinoma (nccRCC)...
  21. doi Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma
    Michael A Davies
    Departments of Melanoma Medical Oncology, Systems Biology, Biostatistics, Pathology, Experimental Therapeutics, and Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Clin Cancer Res 18:1120-8. 2012
    ..Tumor biopsies were analyzed for activating mutations in BRAF and NRAS, and for expression of P-extracellular signal-regulated kinase (P-ERK) and P-S6 proteins...
  22. doi Papillary renal cell carcinoma: radiologic-pathologic correlation and spectrum of disease
    Raghunandan Vikram
    Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Radiographics 29:741-54; discussion 755-7. 2009
    ..A mass that enhances to a lesser degree is likely to be a non-clear cell RCC. It is common for metastatic lesions from pRCC to show enhancement characteristics similar to those of the primary tumor and be hypovascular...
  23. doi Metastases to the liver from neuroendocrine tumors: effect of duration of scan acquisition on CT perfusion values
    Chaan S Ng
    From the Departments of Diagnostic Radiology C S N, E F A, D H H, C C, Biostatistics B P H, Imaging Physics A G C, and Gastrointestinal Medical Oncology J Y, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1473, Houston, TX 77030 4009
    Radiology 269:758-67. 2013
    ..To assess the effects of acquisition duration on computed tomographic (CT) perfusion parameter values in neuroendocrine liver metastases and normal liver tissue...
  24. ncbi CT quantification of effects of thalidomide in patients with metastatic renal cell carcinoma
    Silvana C Faria
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    AJR Am J Roentgenol 189:378-85. 2007
    ..Our objective was to use functional CT to evaluate the effects of thalidomide in patients with metastatic renal cell carcinoma...
  25. doi A phase II trial of gemcitabine plus capecitabine for metastatic renal cell cancer previously treated with immunotherapy and targeted agents
    Nizar M Tannir
    Genitourinary Medical Oncology Department, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Urol 180:867-72; discussion 872. 2008
    ..We assessed the clinical activity and safety of gemcitabine plus capecitabine in patients with metastatic renal cell cancer previously treated with immunotherapy...
  26. doi Semiautomated motion correction of tumors in lung CT-perfusion studies
    Adam Chandler
    Department of Imaging Physics, MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX 77030, USA
    Acad Radiol 18:286-93. 2011
    ..To compare the relative performance of one-dimensional (1D) manual, rigid-translational, and nonrigid registration techniques to correct misalignment of lung tumor anatomy acquired from computed tomography perfusion (CTp) datasets...
  27. pmc A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma
    Kevin B Kim
    Department of Melanoma Medical Oncology, MD Anderson Cancer Center, The University of Texas, Houston, Texas 77030, USA
    Melanoma Res 22:294-301. 2012
    ..05). Cilengitide was well tolerated by patients in both the treatment arms but had minimal clinical efficacy as a single-agent therapy for metastatic melanoma, and the efficacy was not related to baseline αvβ3 expression...
  28. pmc NRAS mutation status is an independent prognostic factor in metastatic melanoma
    John A Jakob
    Department of Melanoma Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 118:4014-23. 2012
    ....
  29. pmc Phase 1 clinical trials in 83 patients with pancreatic cancer: The M. D. Anderson Cancer Center experience
    Christos Vaklavas
    Department of Investigational Cancer Therapeutics, Phase I Clinical Trials Program, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 117:77-85. 2011
    ..The purpose of this study was to report the presenting characteristics and outcomes of patients with locally advanced or metastatic pancreatic cancer treated on phase 1 clinical trials at a single institution...
  30. ncbi Improved tolerability and quality of life with maintained efficacy using twice-daily low-dose interferon-alpha-2b: results of a randomized phase II trial of low-dose versus intermediate-dose interferon-alpha-2b in patients with metastatic renal cell carci
    Nizar M Tannir
    Department of Genitourinary Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:2254-61. 2006
    ..In a randomized Phase II trial, the authors tested the hypothesis that twice-daily low-dose IFN is more effective than daily intermediate-dose IFN in patients with metastatic renal cell cancer (MRCC)...
  31. pmc Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer
    Siqing Fu
    Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Gynecol Oncol 126:47-53. 2012
    ..On the basis of reversal of taxane resistance with AKT inhibition, we initiated a phase I trial of the AKT inhibitor perifosine with docetaxel in taxane and platinum-resistant or refractory epithelial ovarian cancer...
  32. ncbi Hemodynamic and morphologic changes after portal vein embolization: differential effects in central and peripheral zones in the liver on multiphasic computed tomography
    Satoshi Kobayashi
    Department of Diagnostic Radiology, Unit 057, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Comput Assist Tomogr 28:804-10. 2004
    ..To evaluate hemodynamic and morphologic effects in the liver after portal vein embolization (PVE)...
  33. pmc Magnetic resonance imaging of therapy-induced necrosis using gadolinium-chelated polyglutamic acids
    Edward F Jackson
    Department of Imaging Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:830-8. 2007
    ....
  34. doi Phase I trial of hepatic arterial infusion of nanoparticle albumin-bound paclitaxel: toxicity, pharmacokinetics, and activity
    Siqing Fu
    Department of Investigational Cancer Therapeutics, Unit 0455, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Mol Cancer Ther 10:1300-7. 2011
    ..HAI nab-paclitaxel showed partial hepatic extraction. At doses 260 mg/m(2) or less given for 1 hour every 3 weeks, the treatment was well-tolerated and showed activity in advanced cancer patients with predominant liver metastases...
  35. ncbi Comparison of CT methods for determining the fat content of the liver
    Yoshihisa Kodama
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 368, Houston TX 77030, USA
    AJR Am J Roentgenol 188:1307-12. 2007
    ..The purpose of this study was to assess which of a number of methods of measuring attenuation on CT scans is best for prediction of hepatic fat content...
  36. doi Imaging and staging of transitional cell carcinoma: part 2, upper urinary tract
    Raghunandan Vikram
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4009, USA
    AJR Am J Roentgenol 192:1488-93. 2009
    ..In this article, we discuss the epidemiology, pathologic characteristics, and patterns of tumor spread. We illustrate and discuss the role of imaging in the diagnosis, staging, and surveillance of TCC of the renal pelvis and the ureter...
  37. doi Imaging and staging of transitional cell carcinoma: part 1, lower urinary tract
    Raghunandan Vikram
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4009, USA
    AJR Am J Roentgenol 192:1481-7. 2009
    ..In this article, we discuss the epidemiology, pathologic characteristics, and patterns of tumor spread of bladder carcinomas. We illustrate and focus on the role of imaging in the diagnosis, staging, and surveillance of TCC...
  38. doi Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors
    Apostolia Maria Tsimberidou
    Phase I Program, Department of Investigational Cancer Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Cancer Chemother Pharmacol 65:235-41. 2010
    ..This phase I first-in-human trial evaluated salirasib, an S-prenyl derivative of thiosalicylic acid that competitively blocks RAS signaling...
  39. doi Significance of upper urinary tract urothelial thickening and filling defect seen on MDCT urography in patients with a history of urothelial neoplasms
    Alan D Xu
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    AJR Am J Roentgenol 195:959-65. 2010
    ....
  40. ncbi Radiologic diagnosis and staging of renal and bladder cancer
    Chaan S Ng
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Semin Roentgenol 41:121-38. 2006
  41. ncbi Imaging of neuroendocrine tumors
    Eric P Tamm
    Department of Radiology, Unit 1264, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Hematol Oncol Clin North Am 21:409-32; vii. 2007
    ..Discussion is restricted to the main imaging modalities used in these tumors: cross-sectional imaging, namely CT and MRI, and nuclear medicine studies...
  42. ncbi In vivo imaging of prostate cancer involving bone in a mouse model
    Vikas Kundra
    Department of Radiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Prostate 67:50-60. 2007
    ..We compared the abilities of clinically relevant imaging modalities to quantify prostate cancer involving bone in a mouse model. Such non-invasive methods are needed pre-clinically to understand tumor biology and to evaluate therapy...
  43. pmc Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma
    Richard W Joseph
    Department of Melanoma Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Immunother 35:66-72. 2012
    ..56 vs. 1.97 y, P<0.0001), and trended toward a decreased response rate (7% vs. 21%, P=0.08). NRAS mutational status is a new candidate biomarkers for selecting patients with melanoma for HD IL-2 treatment...
  44. pmc Small increases in serum creatinine are associated with prolonged ICU stay and increased hospital mortality in critically ill patients with cancer
    Joshua Samuels
    Division of Renal Diseases and Hypertension, University of Texas Health Science Center at Houston, 6431 Fannin St, MSB 5 134, Houston, TX 77030, USA
    Support Care Cancer 19:1527-32. 2011
    ..We evaluated the effects on hospital mortality and ICU length of stay of small changes in creatinine following admission to the intensive care unit...
  45. pmc Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer
    Razelle Kurzrock
    The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 29:2660-6. 2011
    ..Early observations of clinical benefit in a phase I study of cabozantinib, which included patients with medullary thyroid cancer (MTC), led to expansion of an MTC-enriched cohort, which is the focus of this article...
  46. doi Phase II trial of curcumin in patients with advanced pancreatic cancer
    Navneet Dhillon
    Department of Investigational Cancer Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 14:4491-9. 2008
    ..We evaluated the clinical biological effects of curcumin (diferuloylmethane), a plant-derived dietary ingredient with potent nuclear factor-kappaB (NF-kappaB) and tumor inhibitory properties, against advanced pancreatic cancer...
  47. doi Positive response to bevacizumab in a patient with metastatic, chemotherapy-refractory urothelial carcinoma
    William E Osai
    Department of Genitourinary Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Anticancer Drugs 19:427-9. 2008
    ..The striking benefit achieved in this heavily treated patient suggests that bevacizumab could have clinically useful antitumor activity in advanced urothelial carcinoma...
  48. ncbi Surgical resection of gastrointestinal stromal tumors after treatment with imatinib
    Robert H I Andtbacka
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Unit 444, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 14:14-24. 2007
    ..In this study, the surgical resection rates and long-term outcomes of patients treated with preoperative imatinib for locally advanced primary, recurrent, or metastatic GISTs were evaluated...
  49. ncbi Multiphasic CT and MRI appearances of extramedullary multiple myeloma involving the stomach, pancreas, and bladder
    Toshiki Kazama
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Clin Imaging 29:263-5. 2005
    ..The stomach and pancreatic lesions were demonstrated as hypervascular nodules on computed tomography (CT), more conspicuous on arterial phase images. Early phase post-contrast imaging might improve the detection of extraosseous myeloma...
  50. pmc Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies
    David S Hong
    Division of Cancer Medicine, Department of Investigational Therapeutics Phase 1 Program, Unit 455, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Clin Cancer Res 15:7061-8. 2009
    ....
  51. ncbi Utility of computed tomography and magnetic resonance imaging staging before completion lymphadenectomy in patients with sentinel lymph node-positive melanoma
    Thomas A Aloia
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 24:2858-65. 2006
    ....
  52. ncbi Histopathological correlates of abnormal pericolic fat on CT in the assessment of colorectal carcinoma
    C S Ng
    Department of Radiology, Addenbrooke s NHS Trust and the University of Cambridge, Cambridge, UK
    Br J Radiol 75:31-7. 2002
    ..However, it is a very helpful CT sign that may draw attention to the presence and site of a potential colonic abnormality...
  53. doi Evaluation of treatment response in patients with metastatic renal cell carcinoma: role of state-of-the-art cross-sectional imaging
    Venkata S Katabathina
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Curr Urol Rep 13:70-81. 2012
    ..Evolving functional imaging techniques such as perfusion and diffusion studies continue to advance the technology beyond assessing changes in tumor size and morphology...
  54. doi Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy
    Yulia Bronstein
    Department of Diagnostic Radiology, M D Anderson Cancer Center, T Boone Pickens Academic Tower, Houston, TX 77030, USA
    AJR Am J Roentgenol 197:W992-W1000. 2011
    ....
  55. ncbi Accuracy of preoperative imaging of hepatic tumors with helical computed tomography
    Courtney L Scaife
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard Unit 444, Houston, Texas 77030, USA
    Ann Surg Oncol 13:542-6. 2006
    ..We reviewed the data from our departmental prospective database with the hypothesis that intraoperative ultrasonography (IOUS) still detects more hepatic tumors than are evident on preoperative helical CT scans...
  56. ncbi Transrectal ultrasound versus magnetic resonance imaging for detection of rectal wall invasion by prostate cancer
    Dan Leibovici
    Department of Urology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Prostate 62:101-4. 2005
    ....
  57. ncbi Minimal preparation CT for the diagnosis of suspected colorectal cancer in the frail and elderly patient
    B C Koo
    Department of Radiology, Addenbrooke s NHS Trust, Cambridge, UK
    Clin Radiol 61:127-39. 2006
    ..An added advantage of MPCT is the ability to identify extra-colonic pathology, and this aspect is also reviewed. In addition, the common radiological features and pitfalls in identifying colonic tumours by MPCT are discussed...
  58. pmc Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer
    Robert L Coleman
    Department of Gynecologic Oncology and Reproductive Medicine, M D Anderson Cancer Center, Houston, TX 77030, USA
    Lancet Oncol 12:1109-17. 2011
    ..We assessed the safety, tolerance, pharmacokinetics, relevant circulating and image-derived biomarkers, and clinical activity of combination aflibercept and docetaxel in this population...
  59. ncbi Effects of smoking and radiotherapy on lung carcinoma in breast carcinoma survivors
    Melissa B Ford
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 98:1457-64. 2003
    ..The authors analyzed smoking, radiation, and both exposures on lung carcinoma development in women who were treated previously for breast carcinoma...
  60. ncbi Incidental lesions found on CT colonography: their nature and frequency
    C S Ng
    Department of Radiology, Unit 57, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Br J Radiol 78:20-1. 2005
  61. ncbi Unusual causes of colonic wall thickening on computed tomography
    D R Turner
    Department of Diagnostic Imaging, Addenbrooke s Hospital NHS Trust, Cambridge, UK
    Clin Radiol 58:191-200. 2003
    ..We present a number of cases demonstrating colonic wall thickening on CT due to rarer diagnoses, which are correlated with the histopathological features. Some of these CT appearances have not been described previously in the literature...
  62. doi Atypical appendicitis: the impact of CT and its management
    T C See
    Department of Radiology, Adenbrooke s Hospital, Cambridge, UK
    J Med Imaging Radiat Oncol 52:140-7. 2008
    ..In this review, we present the range of presentations of atypical appendicitis, the variety of management options and the potential value of CT...
  63. ncbi CT and angiographic features of hepatic inflammatory myofibroblastic tumour
    T C See
    Department of Radiology, Royal Free Hospital, London, UK
    Clin Radiol 60:718-22. 2005
  64. ncbi The impact of helical computed tomography on the diagnosis of unsuspected inflammatory bowel disease in the large bowel
    G Markose
    Department of Radiology, Addenbrooke s NHS Trust, Cambridge, UK
    Eur Radiol 13:107-13. 2003
    ..Nevertheless, CT is able to identify clinically unsuspected cases and radiologists should be alert to this treatable and not infrequently elusive diagnosis...
  65. ncbi Appendicitis: spectrum of appearances on helical CT
    T C See
    University Department of Radiology, Addenbrooke s NHS Trust and the University of Cambridge, Hills Road, Cambridge CB2 2QQ, UK
    Br J Radiol 75:775-81. 2002
    ..This pictorial review illustrates the spectrum of radiological signs and appearances of appendicitis on helical CT...
  66. ncbi Analysis of diagnostic confidence and diagnostic accuracy: a unified framework
    C S Ng
    Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Br J Radiol 80:152-60. 2007
    ..Failure to take adequate account of incorrect diagnoses is potentially misleading. We suggest that a comprehensive analysis of diagnostic confidence requires the incorporation of diagnostic accuracy...