Wayne Newhauser

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Dosimetric impact of tantalum markers used in the treatment of uveal melanoma with proton beam therapy
    Wayne D Newhauser
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Phys Med Biol 52:3979-90. 2007
  2. ncbi request reprint Monte Carlo simulations of the dosimetric impact of radiopaque fiducial markers for proton radiotherapy of the prostate
    Wayne Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Phys Med Biol 52:2937-52. 2007
  3. ncbi request reprint Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants?
    Wayne D Newhauser
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Phys Med Biol 53:2327-44. 2008
  4. ncbi request reprint Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm
    Wayne Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Phys Med Biol 52:4569-84. 2007
  5. ncbi request reprint Neutron radiation area monitoring system for proton therapy facilities
    W D Newhauser
    The University of Texas M D Anderson Cancer Center Proton Therapy Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Radiat Prot Dosimetry 115:149-53. 2005
  6. doi request reprint The risk of developing a second cancer after receiving craniospinal proton irradiation
    Wayne D Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA
    Phys Med Biol 54:2277-91. 2009
  7. ncbi request reprint Monte Carlo simulations of a nozzle for the treatment of ocular tumours with high-energy proton beams
    Wayne Newhauser
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Phys Med Biol 50:5229-49. 2005
  8. ncbi request reprint Assessing the risk of second malignancies after modern radiotherapy
    Wayne D Newhauser
    MD Anderson Cancer Center Radiation Oncology, 1515 Holcombe Boulevard Houston, Texas 77030 4009, USA
    Nat Rev Cancer 11:438-48. 2011
  9. ncbi request reprint Dosimetry for ocular proton beam therapy at the Harvard Cyclotron Laboratory based on the ICRU Report 59
    W D Newhauser
    Massachusetts General Hospital, Boston 02114, USA
    Med Phys 29:1953-61. 2002
  10. doi request reprint Monte Carlo simulations of neutron spectral fluence, radiation weighting factor and ambient dose equivalent for a passively scattered proton therapy unit
    Yuanshui Zheng
    Department of Radiation Physics, Unit 94, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 53:187-201. 2008

Detail Information

Publications30

  1. ncbi request reprint Dosimetric impact of tantalum markers used in the treatment of uveal melanoma with proton beam therapy
    Wayne D Newhauser
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Phys Med Biol 52:3979-90. 2007
    ..To avoid this situation, fiducials should be positioned laterally or distally with respect to the target volume...
  2. ncbi request reprint Monte Carlo simulations of the dosimetric impact of radiopaque fiducial markers for proton radiotherapy of the prostate
    Wayne Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Phys Med Biol 52:2937-52. 2007
    ..A 0.9 mm diameter, 3.1 mm long cylindrical stainless steel marker provides good radiographic visibility yet perturbs the proton dose distribution in the prostate by less than 8% when using a parallel opposed lateral beam arrangement...
  3. ncbi request reprint Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants?
    Wayne D Newhauser
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Phys Med Biol 53:2327-44. 2008
    ..In this approach, the kVCT images provided good delineation of soft tissues due to high-contrast resolution, and the streak-free MVCT images provided smaller range uncertainties because they did not require artifact correction...
  4. ncbi request reprint Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm
    Wayne Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Phys Med Biol 52:4569-84. 2007
    ..The model presented here provided a means to reduce by several months the time required to prepare an analytical treatment planning system for patient treatments...
  5. ncbi request reprint Neutron radiation area monitoring system for proton therapy facilities
    W D Newhauser
    The University of Texas M D Anderson Cancer Center Proton Therapy Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Radiat Prot Dosimetry 115:149-53. 2005
    ..The system performs with a mean time between failures of >6 months. Required data storage capabilities and application execution times are met with inexpensive off-the-shelf computer hardware...
  6. doi request reprint The risk of developing a second cancer after receiving craniospinal proton irradiation
    Wayne D Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA
    Phys Med Biol 54:2277-91. 2009
    ..Simulations revealed that both passively scattered and scanned-beam proton therapies confer significantly lower risks of second cancers than 6 MV conventional and intensity-modulated photon therapies...
  7. ncbi request reprint Monte Carlo simulations of a nozzle for the treatment of ocular tumours with high-energy proton beams
    Wayne Newhauser
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    Phys Med Biol 50:5229-49. 2005
    ..The study revealed that, after a significant development effort, a Monte Carlo model of a proton therapy apparatus is sufficiently accurate and fast for commissioning a treatment planning system...
  8. ncbi request reprint Assessing the risk of second malignancies after modern radiotherapy
    Wayne D Newhauser
    MD Anderson Cancer Center Radiation Oncology, 1515 Holcombe Boulevard Houston, Texas 77030 4009, USA
    Nat Rev Cancer 11:438-48. 2011
    ..Therefore, there is a need to develop risk assessments based on our current knowledge of radiation-induced carcinogenesis...
  9. ncbi request reprint Dosimetry for ocular proton beam therapy at the Harvard Cyclotron Laboratory based on the ICRU Report 59
    W D Newhauser
    Massachusetts General Hospital, Boston 02114, USA
    Med Phys 29:1953-61. 2002
    ..That difference is small compared with the experimental uncertainties and is clinically insignificant. In June of 1998, we adopted the IC-based method as our standard practice for the ocular beam...
  10. doi request reprint Monte Carlo simulations of neutron spectral fluence, radiation weighting factor and ambient dose equivalent for a passively scattered proton therapy unit
    Yuanshui Zheng
    Department of Radiation Physics, Unit 94, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 53:187-201. 2008
    ..Comparisons of in-air calculations with in-phantom calculations indicated that the in-air method yielded a conservative estimation of stray neutron radiation exposure for a prostate cancer patient...
  11. ncbi request reprint Monte Carlo study of neutron dose equivalent during passive scattering proton therapy
    Yuanshui Zheng
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 52:4481-96. 2007
    ..The analytical model predicted H/D values within 28% of those obtained in simulations; this value is within typical neutron measurement uncertainties...
  12. ncbi request reprint Patient neutron dose equivalent exposures outside of the proton therapy treatment field
    J C Polf
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 130, Houston, TX 77030, USA
    Radiat Prot Dosimetry 115:154-8. 2005
    ..35 and 0.60 mSv Gy(-1) from the simulations and measurements, respectively. At all locations, the predicted H/D values are within a factor of 2 and 3 of the measured result for no modulation and 8.2 cm of modulation, respectively...
  13. doi request reprint Equivalent dose and effective dose from stray radiation during passively scattered proton radiotherapy for prostate cancer
    Jonas Fontenot
    The University of Texas Graduate School of Biomedical Sciences at Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Phys Med Biol 53:1677-88. 2008
    ..Neutrons created in the nozzle predominated effective dose, though neutrons created in the patient contributed substantially to the equivalent dose in organs near the proton field. Photons contributed less than 15% to equivalent doses...
  14. pmc Dose perturbations from implanted helical gold markers in proton therapy of prostate cancer
    Annelise Giebeler
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Appl Clin Med Phys 10:2875. 2009
    ..Dose perturbation was not observed for the small markers, but these markers were deemed too fragile for transrectal implantation in the prostate...
  15. ncbi request reprint Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions
    U Titt
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 53:4455-70. 2008
    ..Hence, the Monte Carlo models of medium- and large-size double scattering proton-therapy nozzles were valid for proton beams in the 100 MeV-250 MeV interval...
  16. pmc Monte Carlo and analytical model predictions of leakage neutron exposures from passively scattered proton therapy
    ANGELICA PEREZ-ANDUJAR
    Department of Radiation Physics, Unit 1202, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030
    Med Phys 40:121714. 2013
    ..The purpose of this study was to develop an analytical model to predict leakage neutron equivalent dose from passively scattered proton beams in the 100-250-MeV interval...
  17. ncbi request reprint Neutron shielding calculations in a proton therapy facility based on Monte Carlo simulations and analytical models: criterion for selecting the method of choice
    U Titt
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 94, Houston, TX 77030, USA
    Radiat Prot Dosimetry 115:144-8. 2005
    ..In this study, the optimum rejection criterion of 10% was found. The mean ratio was 26, 62% of all receptor locations showed a ratio between 0.9 and 10, and 92% were between 1 and 100...
  18. ncbi request reprint Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: a Monte Carlo study
    M Bues
    The University of Texas M D Anderson Cancer Center, Department of Radiation Physics, 1515 Holcombe Blvd, Unit 94, Houston, Texas 77030, USA
    Radiat Prot Dosimetry 115:164-9. 2005
    ..Multileaf collimation is compared with a differential spot-weighting technique of sharpening the lateral dose falloff...
  19. ncbi request reprint Design tools for proton therapy nozzles based on the double-scattering foil technique
    J D Fontenot
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 130, Houston, TX 77030, USA
    Radiat Prot Dosimetry 116:211-5. 2005
    ..8 in the gonadal region (50 cm from isocentre) and 3.4 in the thyroid region (21 cm from isocentre). The global ratio of predicted-to-measured H/D is 2.6...
  20. pmc Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer?
    Adam D Melancon
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, USA
    Radiother Oncol 85:251-9. 2007
    ....
  21. ncbi request reprint Calculations of neutron dose equivalent exposures from range-modulated proton therapy beams
    Jerimy C Polf
    Department of Radiation Physics, Unit 130, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Phys Med Biol 50:3859-73. 2005
    ..In general, H/D increased with increasing range modulation at all locations studied, and the maximum H/D exposures shifted away from isocentre...
  22. pmc Four-dimensional computed tomography-based treatment planning for intensity-modulated radiation therapy and proton therapy for distal esophageal cancer
    Xiaodong Zhang
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 72:278-87. 2008
    ....
  23. pmc Effect of anatomic motion on proton therapy dose distributions in prostate cancer treatment
    Xiaodong Zhang
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:620-9. 2007
    ..To determine the dosimetric impact of interfraction anatomic movements in prostate cancer patients receiving proton therapy...
  24. doi request reprint Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer
    Phillip J Taddei
    The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 94, Houston, TX 77030, USA
    Phys Med Biol 53:2131-47. 2008
    ....
  25. ncbi request reprint Determination of output factors for small proton therapy fields
    Jonas D Fontenot
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Med Phys 34:489-98. 2007
    ..We conclude that measuring D/MU without the range compensator present provides more reliable results than measuring it with the range compensator in place...
  26. ncbi request reprint Monte Carlo calculations and measurements of absorbed dose per monitor unit for the treatment of uveal melanoma with proton therapy
    Nicholas Koch
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 53:1581-94. 2008
    ..It is thus feasible to use the Monte Carlo method as a routine absolute dose algorithm for ocular proton therapy...
  27. doi request reprint Monte Carlo investigation of collimator scatter of proton-therapy beams produced using the passive scattering method
    Uwe Titt
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 94, Houston, TX 77030, USA
    Phys Med Biol 53:487-504. 2008
    ....
  28. ncbi request reprint Changes in the pelvic anatomy after an IMRT treatment fraction of prostate cancer
    Renaud de Crevoisier
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:1529-36. 2007
    ..To quantify the three-dimensional variations of pelvic anatomy after a single treatment fraction...
  29. ncbi request reprint Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification
    Jerimy C Polf
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Med Phys 34:4213-8. 2007
    ....
  30. ncbi request reprint Proton beam dosimetry for radiosurgery: implementation of the ICRU Report 59 at the Harvard Cyclotron Laboratory
    Wayne D Newhauser
    Massachusetts General Hospital, Northeast Proton Therapy Center, Department of Radiation Oncology, Boston, MA 02114, USA
    Phys Med Biol 47:1369-89. 2002
    ..The ionization chamber technique exhibited superior reproducibility and was adopted in our standard clinical practice for radiosurgery...

Research Grants3

  1. Prediction of Second Cancer Risks for Children Treated with Proton - vs. - Photon
    Wayne Newhauser; Fiscal Year: 2009
    ..In the future, we expect that the lower-risk treatments will result in fewer second cancers and this will translate into longer, higher-quality lives for survivors of childhood cancer (presently 270,000 persons in the United States). ..
  2. Prediction of Second Cancer Risks for Children Treated with Proton - vs. - Photon
    Wayne D Newhauser; Fiscal Year: 2010
    ..In the future, we expect that the lower-risk treatments will result in fewer second cancers and this will translate into longer, higher-quality lives for survivors of childhood cancer (presently 270,000 persons in the United States). ..