Kendall W Nettles

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. Nwachukwu J, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, et al. Predictive features of ligand-specific signaling through the estrogen receptor. Mol Syst Biol. 2016;12:864 pubmed publisher
    ..Thus, incorporating systems structural analyses with quantitative chemical biology reveals how ligands can achieve distinct allosteric signaling outcomes through ER?. ..
  2. Nwachukwu J, Srinivasan S, Bruno N, Parent A, Hughes T, Pollock J, et al. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. elife. 2014;3:e02057 pubmed publisher
    ..DOI: http://dx.doi.org/10.7554/eLife.02057.001. ..
  3. Nwachukwu J, Srinivasan S, Bruno N, Nowak J, Wright N, Minutolo F, et al. Systems Structural Biology Analysis of Ligand Effects on ER? Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chem Biol. 2017;24:35-45 pubmed publisher
  4. Nettles K, Gil G, Nowak J, M├ętivier R, Sharma V, Greene G. CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor. Mol Endocrinol. 2008;22:263-72 pubmed
    ..This work further demonstrates that CBP dosage is a critical regulator of gene-specific signal integration between the ER- and NFkappaB-signaling pathways. ..