Robert M Nelson

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint Appropriate risk exposure in environmental health research. The Kennedy-Krieger lead abatement study
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, 9th Floor, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    Neurotoxicol Teratol 24:445-9. 2002
  2. ncbi request reprint Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of Dr. Nelson
    Robert M Nelson
    Department of Anesthesiology, Critical Care, The Children s Hospital of Philadelphia, Philadelphia, PA
    Acad Emerg Med 14:e43-4. 2007
  3. ncbi request reprint Voluntariness of consent for research: an empirical and conceptual review
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19104 4399, USA
    Med Care 40:V69-80. 2002
  4. ncbi request reprint Imagining the developmentally disabled and mentally retarded: an introduction
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    Ment Retard Dev Disabil Res Rev 9:1-2. 2003
  5. doi request reprint Assessment of parental decision-making in neonatal cardiac research: a pilot study
    Aruna T Nathan
    Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania, Pennsylvania, USA
    J Med Ethics 36:106-10. 2010
  6. pmc The decision making control instrument to assess voluntary consent
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Med Decis Making 31:730-41. 2011
  7. ncbi request reprint Risk perception and decision processes underlying informed consent to research participation
    William W Reynolds
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Center for Research Integrity, CHOP North Room 1511, 3405 Civic Center Boulevard, Philadelphia, PA 19104, USA
    Soc Sci Med 65:2105-15. 2007
  8. pmc Factors related to voluntary parental decision-making in pediatric oncology
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatrics 129:903-9. 2012
  9. pmc Challenges in measuring a new construct: perception of voluntariness for research and treatment decision making
    Victoria A Miller
    The Children s Hospital of Philadelphia, Civic Center, Philadelphia, PA 19104, USA
    J Empir Res Hum Res Ethics 4:21-31. 2009
  10. pmc Relationship of external influence to parental distress in decision making regarding children with a life-threatening illness
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr Psychol 36:1102-12. 2011

Detail Information

Publications39

  1. ncbi request reprint Appropriate risk exposure in environmental health research. The Kennedy-Krieger lead abatement study
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, 9th Floor, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    Neurotoxicol Teratol 24:445-9. 2002
  2. ncbi request reprint Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of Dr. Nelson
    Robert M Nelson
    Department of Anesthesiology, Critical Care, The Children s Hospital of Philadelphia, Philadelphia, PA
    Acad Emerg Med 14:e43-4. 2007
  3. ncbi request reprint Voluntariness of consent for research: an empirical and conceptual review
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19104 4399, USA
    Med Care 40:V69-80. 2002
    ..Policy responses may be appropriate where the probability of control is too high...
  4. ncbi request reprint Imagining the developmentally disabled and mentally retarded: an introduction
    Robert M Nelson
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    Ment Retard Dev Disabil Res Rev 9:1-2. 2003
  5. doi request reprint Assessment of parental decision-making in neonatal cardiac research: a pilot study
    Aruna T Nathan
    Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania, Pennsylvania, USA
    J Med Ethics 36:106-10. 2010
    ..To assess parental permission for a neonate's research participation using the MacArthur competence assessment tool for clinical research (MacCAT-CR), specifically testing the components of understanding, appreciation, reasoning and choice...
  6. pmc The decision making control instrument to assess voluntary consent
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Med Decis Making 31:730-41. 2011
    ..The decision to participate in a research intervention or to undergo medical treatment should be both informed and voluntary...
  7. ncbi request reprint Risk perception and decision processes underlying informed consent to research participation
    William W Reynolds
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Center for Research Integrity, CHOP North Room 1511, 3405 Civic Center Boulevard, Philadelphia, PA 19104, USA
    Soc Sci Med 65:2105-15. 2007
    ..We discuss participants' use of decision-making heuristics in the context of recent research on affect and decision processes, and we consider the implications of these findings for researchers...
  8. pmc Factors related to voluntary parental decision-making in pediatric oncology
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatrics 129:903-9. 2012
    ..The aim of the current study was to examine demographic and contextual correlates of voluntariness in parents making research or treatment decisions for their children with cancer...
  9. pmc Challenges in measuring a new construct: perception of voluntariness for research and treatment decision making
    Victoria A Miller
    The Children s Hospital of Philadelphia, Civic Center, Philadelphia, PA 19104, USA
    J Empir Res Hum Res Ethics 4:21-31. 2009
    ..The strategies discussed here can be adapted by other researchers who are considering a scale development study related to the empirical study of ethics...
  10. pmc Relationship of external influence to parental distress in decision making regarding children with a life-threatening illness
    Victoria A Miller
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr Psychol 36:1102-12. 2011
    ..To examine the relationship of external influence to parental distress when making a decision about research or treatment for a child with a life-threatening illness and to test potential moderators of this relationship...
  11. ncbi request reprint Challenges in the conduct of emergency research in children: a workshop report
    Robert M Nelson
    The Children s Hospital of Philadelphia, Philadelphia, PA
    Am J Bioeth 6:W1-9. 2006
  12. ncbi request reprint Is a "wage-payment" model for research participation appropriate for children?
    Stephen J Bagley
    College of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA
    Pediatrics 119:46-51. 2007
    ..Our goal was to evaluate the applicability of a "wage-payment" model to inducements for children to participate in research...
  13. ncbi request reprint Variation in standards of research compensation and child assent practices: a comparison of 69 institutional review board-approved informed permission and assent forms for 3 multicenter pediatric clinical trials
    Michael B Kimberly
    Pediatric Generalist Research Group, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatrics 117:1706-11. 2006
    ....
  14. ncbi request reprint A developmental approach to child assent for nontherapeutic research
    Victoria A Miller
    Center for Research Integrity, The Children s Hospital of Philadelphia, PA 19104, USA
    J Pediatr 149:S25-30. 2006
    ....
  15. ncbi request reprint Advising parents about children's participation in clinical research
    K Sarah Hoehn
    Department of Anesthesiology and Critical Care Medicine, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pediatr Ann 33:778-81. 2004
    ..If there are unanswered questions, the pediatrician should encourage a parent to contact the researcher, or offer (with the parent's permission) to contact the researchers on the parent's behalf...
  16. doi request reprint Is there an objective way to compare research risks?
    John Rossi
    Community Health and Prevention, Drexel University School of Public Health, 1505 Race Street, Bellet Building, 11th Floor, Philadelphia, PA 19102, USA
    J Med Ethics 38:423-7. 2012
    ..Instead, the authors suggest that a deliberative approach may be a more viable candidate for future development. Such an approach could be informed by methods such as SERR without being rigidly bound to them...
  17. doi request reprint The Children's Hospital of Philadelphia's experience with donation after cardiac death
    Maryam Y Naim
    The Children s Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, Philadelphia, PA, USA
    Crit Care Med 36:1729-33. 2008
    ..To describe our experience with pediatric donation after cardiac death...
  18. ncbi request reprint Parental decision-making in congenital heart disease
    K Sarah Hoehn
    Division of Critical Care Medicine, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Cardiol Young 14:309-14. 2004
    ..To explore whether prenatal diagnosis of congenital heart disease is associated with lower levels of parental distress and greater satisfaction with decisions about cardiothoracic surgery when compared to postnatal diagnosis...
  19. ncbi request reprint Exception from informed consent for pediatric resuscitation research: community consultation for a trial of brain cooling after in-hospital cardiac arrest
    Marilyn C Morris
    Department of Anesthesia and Critical Care Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatrics 114:776-81. 2004
    ....
  20. ncbi request reprint Ethical challenges in neonatal research: Summary report of the ethics group of the newborn drug development initiative
    Gerri R Baer
    Department of Pediatrics, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Clin Ther 28:1399-407. 2006
    ..The Newborn Drug Development Initiative (NDDI) was established to address the lack of substantive data supporting efficacy and safety of drugs in the neonate...
  21. ncbi request reprint Child assent and parental permission in pediatric research
    Wilma C Rossi
    Department of Pediatrics, The Children s Hospital of Philadelphia, PA 19104, USA
    Theor Med Bioeth 24:131-48. 2003
    ..We suggest a developmental approach, viewing assent as a continuum ranging from mere affirmation in the youngest children to the equivalent of the informed consent process in the mature adolescent...
  22. ncbi request reprint Self-determination is not an appropriate model for understanding parental permission and child assent
    E Joseph Denham
    Anesth Analg 94:1049-51. 2002
  23. doi request reprint Empirical data and the acceptability of research risk: a commentary on the charitable participation standard
    William W Reynolds
    Arch Pediatr Adolesc Med 162:88-90. 2008
  24. doi request reprint Institutional review boards lack the moral legitimacy to reinterpret subpart D
    Robert M Nelson
    United States Food and Drug Administration, Rockville, MD 20057, USA
    Am J Bioeth 8:37-9. 2008
  25. ncbi request reprint We should reject passive resignation in favor of requiring the assent of younger children for participation in nonbeneficial research
    Robert M Nelson
    University of Pennsylvania and The Children s Hospital of Philadelphia
    Am J Bioeth 3:11-3. 2003
  26. ncbi request reprint Minimal risk, yet again
    Robert M Nelson
    J Pediatr 150:570-2. 2007
  27. ncbi request reprint Certificates of confidentiality in research: rationale and usage
    Zachary N Cooper
    The College, University of Chicago, Chicago, IL 60637, USA
    Genet Test 8:214-20. 2004
    ..These findings show that COCs are often congregated within institutions and by particular individuals. This may be because others are unaware of COCs or because others do not believe they are necessary or useful...
  28. ncbi request reprint An open letter to institutional review boards considering Northfield Laboratories' PolyHeme trial
    Ken Kipnis
    University of Hawaii, Manoa, USA
    Am J Bioeth 6:18-21. 2006
    ..Blood-the standard treatment for hemorrhagic shock-is not available in ambulances but is available in hospitals. The authors argue that the in-hospital stage of the study fails to meet ethical and regulatory standards...
  29. ncbi request reprint In defense of a single standard of research risk for all children
    Robert M Nelson
    J Pediatr 147:565-6. 2005
  30. ncbi request reprint Pediatric research and the federal minimal risk standard
    Lainie Friedman Ross
    JAMA 295:759; author reply 759-60. 2006
  31. ncbi request reprint Are research ethics standards satisfied in pediatric journal publications?
    Eric Weil
    MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, Illinois 60637, USA
    Pediatrics 110:364-70. 2002
    ..Although many studies document them poorly, most published research undergoes IRB review and has IC procedures. Less is known about research published in pediatric journals, and how child health research is determined to be exempt...
  32. ncbi request reprint Child assent and parental permission: a comment on Tait's "Do they understand?"
    Robert M Nelson
    Anesthesiology 98:597-8. 2003
  33. ncbi request reprint Randomized, controlled trials as minimal risk: an ethical analysis
    Marilyn C Morris
    Department of Pediatrics, Division of Pediatric Critical Care, The Children s Hospital of New York Presbyterian, Columbia University, New York, NY, USA
    Crit Care Med 35:940-4. 2007
    ....
  34. ncbi request reprint Trials and errors: barriers to oversight of research conducted under the emergency research consent waiver
    Ken Kipnis
    Department of Philosophy, University of Hawaii at Manoa, Hawaii, USA
    IRB 28:16-9. 2006
  35. ncbi request reprint Moving beyond the consent document in research on informed consent
    Victoria A Miller
    Arch Pediatr Adolesc Med 159:396-7. 2005
  36. ncbi request reprint A paradigm for inpatient resuscitation research with an exception from informed consent
    Marilyn C Morris
    Department of Pediatrics, Children s Hospital of New York Presbyterian, Columbia University, New York, NY, USA
    Crit Care Med 34:2567-75. 2006
    ....
  37. ncbi request reprint Parental opinions about clinical research
    Marilyn C Morris
    Department of Pediatrics, Division of Critical Care Medicine, The Children s Hospital of New York Presbyterian, Columbia University, New York, New York 10032, USA
    J Pediatr 151:532-7, 537.e1-5. 2007
    ..To characterize parental perception of clinical research, particularly in emergency settings. To identify specific aspects of clinical research that concern parents and to discuss how these concerns can be addressed...
  38. ncbi request reprint Informed consent for genetic research involving pleiotropic genes: an empirical study of ApoE research
    Zachary N Cooper
    London School of Economics, London, UK
    IRB 28:1-11. 2006
  39. ncbi request reprint Weighing the risks of G-CSF administration, leukopheresis, and standard marrow harvest: ethical and safety considerations for normal pediatric hematopoietic cell donors
    Michael A Pulsipher
    Primary Children s Medical Center, Salt Lake City, Utah 84113, USA
    Pediatr Blood Cancer 46:422-33. 2006
    ..Short and long-term risks of G-CSF administration and leukopheresis are not well understood in the pediatric population...

Research Grants3

  1. Developing a Measure of Voluntary Consent for Protocol-Based Treatment Decisions
    Robert Nelson; Fiscal Year: 2007
    ..An instrument to assess the voluntary choice of a research participant will be an important addition to existing instruments so we may assess whether an individual's consent is both informed and voluntary. ..