Research Topics
| Mohamed NaguibSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
Predictive performance of three multivariate difficult tracheal intubation models: a double-blind, case-controlled studyMohamed Naguib
Department of Anesthesiology and Pain Medicine, Unit 409, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Anesth Analg 102:818-24. 2006..This model is 82.5% sensitive and 85.6% specific with an area under the receiver operating characteristic curve of 0.90...
Succinylcholine dosage and apnea-induced hemoglobin desaturation in patientsMohamed Naguib
Department of Anesthesia, King Saud University, Riyadh, Saudi Arabia
Anesthesiology 102:35-40. 2005..6 mg/kg would allow a faster recovery of spontaneous ventilation and reduction in the incidence of hemoglobin desaturation during the period of apnea in simulated complete upper airway obstruction situations...
The effects of melatonin premedication on propofol and thiopental induction dose-response curves: a prospective, randomized, double-blind studyMohamed Naguib
Department of Anesthesiology and Pain Medicine, University of Texas M D Anderson Cancer Center, Unit 409, 1400 Holcombe Boulevard, Houston, TX 77030, USA
Anesth Analg 103:1448-52. 2006..v.anesthetics has not been documented. We studied the effect of melatonin premedication on the propofol and thiopental dose-response curves for abolition of responses to verbal commands and eyelash stimulation...
Melatonin and anesthesia: a clinical perspectiveMohamed Naguib
Department of Anesthesiology and Pain Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Pineal Res 42:12-21. 2007..Further work is needed to better understand the general anesthetic properties of melatonin at the molecular, cellular, and systems levels...
Neuromuscular monitoring and postoperative residual curarisation: a meta-analysisM Naguib
Department of Anesthesiology and Pain Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Br J Anaesth 98:302-16. 2007..We could not demonstrate that the use of an intraoperative neuromuscular function monitor decreased the incidence of PORC...
Sugammadex: another milestone in clinical neuromuscular pharmacologyMohamed Naguib
Department of Anesthesiology and Pain Medicine, Unit 409, Anderson Cancer Center, The University of Texas M D, Houston, Texas 77030, USA
Anesth Analg 104:575-81. 2007..The clinical use of sugammadex promises to eliminate many of the shortcomings in our current practice with regard to the antagonism of rocuronium and possibly other steroidal neuromuscular blockers...
MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain modelsM Naguib
1Department of Anesthesiology and Pain Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Br J Pharmacol 155:1104-16. 2008..In this report, we describe the pharmacological characteristics of MDA7 (1-[(3-benzyl-3-methyl-2,3-dihydro-1-benzofuran-6-yl)carbonyl]piperidine), a novel CB(2) receptor agonist...
Update on neuromuscular pharmacologyMohamed Naguib
Department of Anesthesiology and Pain Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Curr Opin Anaesthesiol 22:483-90. 2009....
The dose of succinylcholine required for excellent endotracheal intubating conditionsMohamed Naguib
Department of Anesthesiology and Pain Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Anesth Analg 102:151-5. 2006..39 (0.29-0.51) mg/kg and 1.6 (1.2-2.0) mg/kg, respectively. It appears that there are no advantages to using doses of succinylcholine larger than 1.5 mg/kg...
Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic painJijun J Xu
Department of Anesthesiology and Perioperative Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Anesth Analg 111:99-109. 2010..In this study, we characterized the pharmacological profile of the novel compound N'-[(3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide (MDA19), a CB2 agonist...
Optimal dose of succinylcholine revisitedMohamed Naguib
Department of Anesthesia, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
Anesthesiology 99:1045-9. 2003..56 mg/kg succinylcholine. Reducing the dose of succinylcholine should allow a more rapid return of spontaneous respiration and airway reflexes...
6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode predictionPhilippe Diaz
Department of Anesthesiology and Pain Medicine, Unit 409, The University of Texas M D Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, Texas 77030, USA
J Med Chem 52:433-44. 2009..A ligand-based homology model of the CB2 binding site was developed, and on the basis of our results, we propose a general binding mode for this class of inverse agonists with CB2...
Propofol: the challenges of formulationMax T Baker
Department of Anesthesia, The University of Iowa College of Medicine, 52242 1009, USA
Anesthesiology 103:860-76. 2005..In addition, a number of propofol prodrugs have been made and evaluated...
The hypnotic and analgesic effects of 2-bromomelatoninMohamed Naguib
Department of Anesthesia, University of Iowa College of Medicine, Iowa City, Iowa, USA
Anesth Analg 97:763-8. 2003..This study provides evidence that 2-bromomelatonin has properties that are desirable in anesthetics or anesthetic adjuvants...
Posttetanic potentiation and fade in the response to tetanic and train-of-four stimulation during succinylcholine-induced blockMohamed Naguib
Department of Anesthesia, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
Anesth Analg 98:1686-91, table of contents. 2004..We also conclude that some characteristics of a Phase II block are evident from an initial dose (i.e., as small as 0.3 mg/kg) of succinylcholine...
Low-dose rocuronium and tracheal intubationMohamed Naguib
Department of Anesthesia, University of Iowa College of Medicine 200, Hawkins Drive, 6JCP, Iowa City, Iowa 52242-1009, USA
Middle East J Anesthesiol 17:193-204. 2003
Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic painPhilippe Diaz
Department of Anesthesiology and Pain Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Med Chem 51:4932-47. 2008..More potent and more CB2-receptor-selective compounds, including compounds 37, 40, and 48, were also discovered...
Role of lipid in sulfite-dependent propofol dimerizationMax T Baker
Department of Anesthesia, The University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
Anesthesiology 100:1235-41. 2004..This study evaluated the role of lipid in sulfite-dependent propofol dimerization by determining the effects of individual fatty acids in soybean oil emulsion and peroxidized lipids in a model system...
The electroencephalographic effects of IV anesthetic doses of melatonin: comparative studies with thiopental and propofolMohamed Naguib
Department of Anesthesia, University of Iowa College of Medicine, Iowa City 52242, USA
Anesth Analg 97:238-43, table of contents. 2003..IMPLICATIONS: Anesthetic doses of melatonin produced effects on processed electroencephalographic variables similar to those of thiopental and propofol...
Residual neuromuscular block: rediscovering the obviousSorin J Brull
Anesth Analg 107:11-4. 2008
Advances in neurobiology of the neuromuscular junction: implications for the anesthesiologistMohamed Naguib
Department of Anesthesia, University of Iowa College of Medicine, Iowa City, 52242-1009, USA
Anesthesiology 96:202-31. 2002
