T W Muir
Affiliation: The Rockefeller University
- Probing the chemical basis of binding activity in an SH3 domain by protein signature analysisT W Muir
The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
Chem Biol 3:817-25. 1996....
- Expressed protein ligation: a general method for protein engineeringT W Muir
Laboratory of Synthetic Protein Chemistry, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 95:6705-10. 1998....
- Rescuing a destabilized protein fold through backbone cyclizationJ A Camarero
The Laboratory of Synthetic Protein Chemistry, New York, NY 10021, USA
J Mol Biol 308:1045-62. 2001..The ability to rescue the destabilized mutant indicates that circularization may be a useful tool in protein engineering programs geared towards generating minimized proteins...
- Peptide chemical ligation inside living cells: in vivo generation of a circular protein domainJ A Camarero
Laboratory of Synthetic Protein Chemistry, The Rockefeller University, New York, NY 10021, USA
Bioorg Med Chem 9:2479-84. 2001..This work represents an important step towards the in vivo generation of small backbone cyclic peptides for use in basic biological research...
- Native chemical ligation of polypeptidesJ A Camarero
The Rockefeller University, New York, New York, USA
Curr Protoc Protein Sci . 2001..Support protocols describe how to obtain the necessary polypeptide fragments using either chemical synthesis or recombinant DNA expression...