K Mrozek

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi Prognostic value of cytogenetic findings in adults with acute myeloid leukemia
    K Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Authur G James Cancer Hospital, The Ohio State University, Columbus 43210 1228, USA
    Int J Hematol 72:261-71. 2000
  2. ncbi Spectral karyotyping reveals 17;22 fusions in a cytogenetically atypical dermatofibrosarcoma protuberans with a large marker chromosome as a sole abnormality
    K Mrozek
    Division of Hematology and Oncology, and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
    Genes Chromosomes Cancer 31:182-6. 2001
  3. ncbi Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study
    K Mrozek
    Division of Hematology and Oncology, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210 1228, USA
    J Clin Oncol 19:2482-92. 2001
  4. ncbi Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q
    Krzysztof Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210 1228, USA
    Genes Chromosomes Cancer 34:137-53. 2002
  5. ncbi Molecular cytogenetic characterization of the KG-1 and KG-1a acute myeloid leukemia cell lines by use of spectral karyotyping and fluorescence in situ hybridization
    Krzysztof Mrozek
    Division of Hematology and Oncology, and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
    Genes Chromosomes Cancer 38:249-52. 2003
  6. ncbi Cytogenetics in acute leukemia
    Krzysztof Mrozek
    Division of Hematology and Oncology, The Comprehensive Cancer Center, The Arthur G James Cancer Hospital and Richard J Solove Research Institute, Room 1248B, The Ohio State University, Columbus, OH 43210 1228, USA
    Blood Rev 18:115-36. 2004
  7. ncbi Clinical importance of cytogenetics in acute myeloid leukaemia
    K Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Room 1248B, Columbus, OH, 43210 1228, USA
    Best Pract Res Clin Haematol 14:19-47. 2001
  8. ncbi BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia
    S M Tanner
    Human Cancer Genetics Program, Ohio State University, 646 Medical Research Facility, 420 West 12th Avenue, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 98:13901-6. 2001

Detail Information

Publications8

  1. ncbi Prognostic value of cytogenetic findings in adults with acute myeloid leukemia
    K Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Authur G James Cancer Hospital, The Ohio State University, Columbus 43210 1228, USA
    Int J Hematol 72:261-71. 2000
    ..In this review, we present an overview of major cytogenetic findings in AML and discuss associations between karyotype and clinical outcome of adults with AML...
  2. ncbi Spectral karyotyping reveals 17;22 fusions in a cytogenetically atypical dermatofibrosarcoma protuberans with a large marker chromosome as a sole abnormality
    K Mrozek
    Division of Hematology and Oncology, and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
    Genes Chromosomes Cancer 31:182-6. 2001
    ..Furthermore, our case demonstrates the usefulness of SKY in detection of a diagnostically relevant 17;22 fusion in DFSP patients who have unusual karyotypic features...
  3. ncbi Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study
    K Mrozek
    Division of Hematology and Oncology, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210 1228, USA
    J Clin Oncol 19:2482-92. 2001
    ....
  4. ncbi Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q
    Krzysztof Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210 1228, USA
    Genes Chromosomes Cancer 34:137-53. 2002
    ..We conclude that SKY considerably enhances the accuracy of karyotype interpretation, and that amplification of chromosomal material may play a greater role in leukemogenesis than has been recognized...
  5. ncbi Molecular cytogenetic characterization of the KG-1 and KG-1a acute myeloid leukemia cell lines by use of spectral karyotyping and fluorescence in situ hybridization
    Krzysztof Mrozek
    Division of Hematology and Oncology, and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
    Genes Chromosomes Cancer 38:249-52. 2003
    ....
  6. ncbi Cytogenetics in acute leukemia
    Krzysztof Mrozek
    Division of Hematology and Oncology, The Comprehensive Cancer Center, The Arthur G James Cancer Hospital and Richard J Solove Research Institute, Room 1248B, The Ohio State University, Columbus, OH 43210 1228, USA
    Blood Rev 18:115-36. 2004
    ..This review summarizes current views on clinical relevance of major cytogenetic findings in adult AML and ALL...
  7. ncbi Clinical importance of cytogenetics in acute myeloid leukaemia
    K Mrozek
    Division of Hematology and Oncology and the Comprehensive Cancer Center, The Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Room 1248B, Columbus, OH, 43210 1228, USA
    Best Pract Res Clin Haematol 14:19-47. 2001
    ..This review presents current information on chromosome abnormalities in AML, and on associations between karyotype and clinical characteristics and outcome of AML patients...
  8. ncbi BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia
    S M Tanner
    Human Cancer Genetics Program, Ohio State University, 646 Medical Research Facility, 420 West 12th Avenue, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 98:13901-6. 2001
    ..Our data suggest that BAALC is a gene implicated in both neuroectodermal and hematopoietic cell functions...