Federico A Monzon

Summary

Affiliation: The Methodist Hospital
Country: USA

Publications

  1. doi request reprint Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis
    Federico A Monzon
    Department of Pathology, The Methodist Hospital Research Institute, Houston, TX, USA
    Mod Pathol 24:1470-9. 2011
  2. pmc Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma
    Chung Che Chang
    Department of Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, Houston TX, USA
    J Hematol Oncol 2:47. 2009
  3. doi request reprint The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer
    Federico A Monzon
    Department of Molecular Diagnostics, The Methodist Hospital Research Institute, Houston, Texas 77030 2703, USA
    Arch Pathol Lab Med 133:1600-6. 2009
  4. doi request reprint Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors
    Federico A Monzon
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Mod Pathol 21:599-608. 2008
  5. doi request reprint Detection of chromosomal aberrations in renal tumors: a comparative study of conventional cytogenetics and virtual karyotyping with single-nucleotide polymorphism microarrays
    Federico A Monzon
    Department of Pathology, The Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas 77030, USA
    Arch Pathol Lab Med 133:1917-22. 2009
  6. doi request reprint Diagnosis of uncertain primary tumors with the Pathwork tissue-of-origin test
    Federico A Monzon
    Department of Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, 6565 Fannin St, MS 205, Houston, TX 77030, USA
    Expert Rev Mol Diagn 10:17-25. 2010
  7. doi request reprint Diagnosis of metastatic neoplasms: molecular approaches for identification of tissue of origin
    Federico A Monzon
    The Methodist Hospital, 6565 Fannin Street, MS205, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:216-24. 2010
  8. pmc Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression test
    Federico A Monzon
    Clinical Genomics Facility, University of Pittsburgh, Pittsburgh, PA, USA
    Diagn Pathol 5:3. 2010
  9. doi request reprint Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin
    Federico A Monzon
    The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX 77030, USA
    J Clin Oncol 27:2503-8. 2009
  10. doi request reprint Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality
    Hyun Jung Kim
    The Methodist Hospital Research Institute, Houston, TX, USA
    Am J Surg Pathol 33:1276-86. 2009

Collaborators

Detail Information

Publications29

  1. doi request reprint Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis
    Federico A Monzon
    Department of Pathology, The Methodist Hospital Research Institute, Houston, TX, USA
    Mod Pathol 24:1470-9. 2011
    ..Further exploration of 8q gain, 14q loss, MYC, HIF1A and EPAS1 (HIF2α) as molecular markers of tumor behavior and prognosis could aid in personalizing medicine for patients with clear-cell renal cell carcinoma...
  2. pmc Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma
    Chung Che Chang
    Department of Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, Houston TX, USA
    J Hematol Oncol 2:47. 2009
    ..The goal of the current study was to evaluate the genetic similarities and differences among PL, DLBCL (AIDS-related and non AIDS-related) and PCM using array-based comparative genomic hybridization...
  3. doi request reprint The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer
    Federico A Monzon
    Department of Molecular Diagnostics, The Methodist Hospital Research Institute, Houston, Texas 77030 2703, USA
    Arch Pathol Lab Med 133:1600-6. 2009
    ..Several recent studies have shown that patients with KRAS mutations in codons 12 or 13 in metastatic tumors do not benefit from anti-epidermal growth factor receptor therapy with cetuximab or panitumumab...
  4. doi request reprint Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors
    Federico A Monzon
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Mod Pathol 21:599-608. 2008
    ....
  5. doi request reprint Detection of chromosomal aberrations in renal tumors: a comparative study of conventional cytogenetics and virtual karyotyping with single-nucleotide polymorphism microarrays
    Federico A Monzon
    Department of Pathology, The Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas 77030, USA
    Arch Pathol Lab Med 133:1917-22. 2009
    ....
  6. doi request reprint Diagnosis of uncertain primary tumors with the Pathwork tissue-of-origin test
    Federico A Monzon
    Department of Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, 6565 Fannin St, MS 205, Houston, TX 77030, USA
    Expert Rev Mol Diagn 10:17-25. 2010
    ..The availability of ancillary gene expression-based molecular tests for tissue of origin determination represents a milestone in cancer patient management as part of the personalized medicine revolution...
  7. doi request reprint Diagnosis of metastatic neoplasms: molecular approaches for identification of tissue of origin
    Federico A Monzon
    The Methodist Hospital, 6565 Fannin Street, MS205, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:216-24. 2010
    ..Patients with these types of tumors show worse outcomes when compared to patients in which a primary tumor is identified. New molecular tests that identify molecular signatures of a tissue of origin have become available...
  8. pmc Identification of tissue of origin in carcinoma of unknown primary with a microarray-based gene expression test
    Federico A Monzon
    Clinical Genomics Facility, University of Pittsburgh, Pittsburgh, PA, USA
    Diagn Pathol 5:3. 2010
    ..However, primary classification remains a challenge in many cases. We evaluated the ability of a microarray-based gene expression test to identify the TOO in tumor specimens from 21 patients with a diagnosis of CUP...
  9. doi request reprint Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin
    Federico A Monzon
    The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX 77030, USA
    J Clin Oncol 27:2503-8. 2009
    ..The aim of this study was to validate a predefined 1,550-gene expression profile for this purpose...
  10. doi request reprint Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality
    Hyun Jung Kim
    The Methodist Hospital Research Institute, Houston, TX, USA
    Am J Surg Pathol 33:1276-86. 2009
    ..We consider that this technique is a feasible and practical approach for resolving difficult-to-diagnose renal tumors in clinical practice...
  11. doi request reprint Reproducibility and performance of virtual karyotyping with SNP microarrays for the detection of chromosomal imbalances in formalin-fixed paraffin-embedded tissues
    Karla Alvarez
    Department of Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX, USA
    Diagn Mol Pathol 19:127-34. 2010
    ..Here, we report the performance and reproducibility of virtual karyotyping of FFPE tissues with Affymetrix SNP arrays...
  12. doi request reprint PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
    Kanishka Sircar
    The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, TX, USA
    J Pathol 218:505-13. 2009
    ..0001), AR (p = 0.025), and to cancer-specific mortality (p = 0.039). PTEN deletion is common in HRPC, with bi-allelic loss correlating to disease-specific mortality and associated with Akt and AR deregulation...
  13. doi request reprint Multiple distinct clones may co-exist in different lineages in myelodysplastic syndromes
    Wan Ting Huang
    Pathology, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX, United States
    Leuk Res 33:847-53. 2009
    ..Further studies are warranted to confirm our findings and to investigate the lineage specific genomic lesions in MDS...
  14. pmc Array-based karyotyping for prognostic assessment in chronic lymphocytic leukemia: performance comparison of Affymetrix 10K2.0, 250K Nsp, and SNP6.0 arrays
    Jill M Hagenkord
    Molecular Pathology and Clinical Genomics, Creighton University Medical Center, Department of Pathology, 601 N 30 Street, Suite 2400, Omaha, NE 68131 2197, USA
    J Mol Diagn 12:184-96. 2010
    ....
  15. doi request reprint Optimization of the Affymetrix GeneChip Mapping 10K 2.0 Assay for routine clinical use on formalin-fixed paraffin-embedded tissues
    Maureen Lyons-Weiler
    Clinical Genomics Facility, University of Pittsburgh, Pittsburgh, PA, USA
    Diagn Mol Pathol 17:3-13. 2008
    ..0 SNP array. This optimized protocol opens up the potential for the GeneChip Mapping assay to be used in the development of clinical test assays...
  16. pmc Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process
    Uma R Chandran
    Departmental of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15260, USA
    BMC Cancer 7:64. 2007
    ..Understanding the differences in the biology of metastatic and organ confined primary tumors is essential for developing new prognostic markers and therapeutic targets...
  17. doi request reprint Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes
    Zoran Gatalica
    Department of Pathology, Creighton University School of Medicine, Omaha, NE 68131, USA
    Hum Pathol 42:1979-88. 2011
    ....
  18. pmc Synchronous clear cell renal cell carcinoma and tubulocystic carcinoma: genetic evidence of independent ontogenesis and implications of chromosomal imbalances in tumor progression
    Gabriela Quiroga-Garza
    Department of Pathology and Genomic Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Diagn Pathol 7:21. 2012
    ..Second, the presence of a ccRCC with varying degrees of differentiation exemplifies the sequence of chromosomal imbalances acquired during tumor progression...
  19. doi request reprint Clinical genomics of renal epithelial tumors
    Jill M Hagenkord
    Department of Pathology, Creighton University School of Medicine, Omaha, NE, USA
    Cancer Genet 204:285-97. 2011
    ..This review summarizes the genetic and genomic changes in the most common types of renal epithelial tumors and highlights the clinical implications of these aberrations...
  20. doi request reprint Molecular classification of adult renal epithelial neoplasms using microRNA expression and virtual karyotyping
    Martin P Powers
    Department of Pathology and Laboratory Medicine, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX, USA
    Diagn Mol Pathol 20:63-70. 2011
    ..In addition, the lack of correlation between miRNA expression and virtual karyotype suggests a non-copy-number-related mechanism for miRNA gene expression regulation in renal neoplasia...
  21. pmc In vitro transcription amplification and labeling methods contribute to the variability of gene expression profiling with DNA microarrays
    Changqing Ma
    Department of Pathology, Center for Pathology Informatics, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15237, USA
    J Mol Diagn 8:183-92. 2006
    ..This study provides evidence that variability in expression data may be caused, in part, by differences in amplification and labeling protocols...
  22. ncbi request reprint Methylation of the ASC gene promoter is associated with aggressive prostate cancer
    Rachael L Collard
    Department of Urology, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Prostate 66:687-95. 2006
    ....
  23. doi request reprint Identification of tissue of origin in body fluid specimens using a gene expression microarray assay
    Gregory A Stancel
    Department of Pathology and Laboratory Medicine, The Methodist Hospital, Houston, Texas 77030, USA
    Cancer Cytopathol 120:62-70. 2012
    ..In the current study, the authors evaluated the Tissue of Origin Test for use with malignant effusion specimens...
  24. pmc Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers
    Catherine I Dumur
    Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, USA
    J Mol Diagn 10:67-77. 2008
    ....
  25. pmc Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays
    Xiaorong Yang
    Department of Radiology, The Methodist Hospital Research Institute, Weill Medical College, Cornell University, Center for Biotechnology and Informatics, Houston, Texas, United States of America
    PLoS ONE 4:e5054. 2009
    ....
  26. doi request reprint Longitudinal analysis of androgen deprivation of prostate cancer cells identifies pathways to androgen independence
    Jason M D'Antonio
    Program in Cellular and Molecular Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA
    Prostate 68:698-714. 2008
    ..Following androgen ablation therapy, the majority of prostate cancer patients develop treatment resistance with a median time of 18-24 months to disease progression...
  27. doi request reprint Contemporary approach to diagnosis and classification of renal cell carcinoma with mixed histologic features
    Kanishka Sircar
    Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Chin J Cancer 32:303-11. 2013
    ....
  28. ncbi request reprint Attenuated familial adenomatous polyposis: a case report with mixed features and review of genotype-phenotype correlation
    Diana N Ionescu
    Department of Pathology and Laboratory Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
    Arch Pathol Lab Med 129:1401-4. 2005
    ..Differences in the APC mutation sites alone cannot completely account for intrafamilial and interfamilial variation in the polyposis phenotypes...
  29. ncbi request reprint Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
    Sooryanarayana Varambally
    Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Cancer Cell 8:393-406. 2005
    ....