Jessica A Mong
Affiliation: The Rockefeller University
- Gonadal steroids reduce the density of axospinous synapses in the developing rat arcuate nucleus: an electron microscopy analysisJ A Mong
Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Comp Neurol 432:259-67. 2001..1999), and here confirm that these changes include an altered synaptic pattern that is strikingly similar to that observed in the adult (Matsumoto and Arai, 1980)...
- GABA mediates steroid-induced astrocyte differentiation in the neonatal rat hypothalamusJ A Mong
Department of Physiology, University of Maryland, Baltimore School of Medicine, Baltimore, MD, USA
J Neuroendocrinol 14:45-55. 2002..Given that GABA is made only in neurones and that its synthesis is increased by oestradiol, we conclude that it acts as a diffusible factor inducing the differentiation of neighbouring astrocytes...
- Perspective: micoarrays and differential display PCR-tools for studying transcript levels of genes in neuroendocrine systemsJessica A Mong
Laboratory of Neurobiology and Behavior, Rockefeller University, New York, New York 10021, USA
Endocrinology 143:2002-6. 2002..With properly designed and well-executed experiments, these methods are powerful tools in the assessment of differentially expressed genes yielding results both expected and unanticipated...
- Ontogeny of sexually dimorphic astrocytes in the neonatal rat arcuateJessica A Mong
Department of Physiology and Program in Neuroscience, University of Maryland, Baltimore School of Medicine, Baltimore, MD 21201, USA
Brain Res Dev Brain Res 139:151-8. 2002..The male versus female difference in astrocyte morphology may contribute to the sexually dimorphic regulation of neuroendrocrine secretions from the pituitary in the adult...
- Glutamate AMPA/kainate receptors, not GABA(A) receptors, mediate estradiol-induced sex differences in the hypothalamusBrigitte J Todd
Department of Physiology, University of Maryland, Baltimore School of Medicine, Baltimore, Maryland 21201, USA
Dev Neurobiol 67:304-15. 2007..Antagonizing AMPA/kainate receptors with NBQX prevented the estradiol-induced increase in spinophilin in females but did not affect spinophilin level in males...
- Estradiol regulation of lipocalin-type prostaglandin D synthase promoter activity: evidence for direct and indirect mechanismsNino Devidze
Laboratory of Neurobiology and Behavior, Rockefeller University, 1230 York Ave, New York, NY 10021, United States
Neurosci Lett 474:17-21. 2010....
- Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brainKhatuna Gagnidze
Laboratory of Neurobiology and Behavior, Rockefeller University, New York, NY, USA
Prog Brain Res 186:97-111. 2010..Thus such high-throughput screening may be a useful initial step in the identification of estrogen-responsive genes involved in the sexual differentiation of brain...
- Methamphetamine facilitates female sexual behavior and enhances neuronal activation in the medial amygdala and ventromedial nucleus of the hypothalamusMary K Holder
Program in Neuroscience, University of Maryland Baltimore School of Medicine, Baltimore, MD 21201, USA
Psychoneuroendocrinology 35:197-208. 2010....
- Steroid modulation of astrocytes in the neonatal brain: implications for adult reproductive functionMargaret M McCarthy
Department of Physiology, University of Maryland, Baltimore, Maryland 21201 1559, USA
Biol Reprod 67:691-8. 2002..Speculation about and evidence in support of the functional significance of this dimorphism to adult reproductive functioning is the topic of this review...
- Estradiol suppresses recovery of REM sleep following sleep deprivation in ovariectomized female ratsMichael D Schwartz
Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, 655 W Baltimore St, Baltimore MD 21201, USA
Physiol Behav 104:962-71. 2011..These results demonstrate that E2 powerfully and specifically suppresses spontaneous and recovery REM sleep in the dark phase, and suggest that ovarian steroids may consolidate circadian sleep-wake rhythms...
- Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behaviorJessica A Mong
Laboratory of Neurobiology and Behavior, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 100:15206-11. 2003..Thus, reducing L-PGDS in the VLPO of oil-treated females mimicked the effect of E2 on activity and arousal and represents a unique molecular pathway through which E2 may modulate these functions...
- Methamphetamine enhances paced mating behaviors and neuroplasticity in the medial amygdala of female ratsMary K Holder
Program in Neuroscience, University of Maryland, Baltimore, School of Medicine Baltimore, MD 21201, USA
Horm Behav 58:519-25. 2010..Taken together, these findings suggest that METH increases female sexual motivation and behavior in the rat potentially via changes in the neural substrate that require repeated exposure to the drug...
- Sleep alterations in an environmental neurotoxin-induced model of parkinsonismKimberly A McDowell
Program in Neuroscience, University of Maryland, School of Medicine, Baltimore, MD, USA
Exp Neurol 226:84-9. 2010..Further characterization of this early, non-motor symptom, may provide potential therapeutic interventions in the treatment of PD...
- Estradiol suppresses rapid eye movement sleep and activation of sleep-active neurons in the ventrolateral preoptic areaMaria M Hadjimarkou
Department of Pharmacology and Experimental Therapeutics, University of Maryland, Baltimore, School of Medicine, Baltimore, MD 21201, USA
Eur J Neurosci 27:1780-92. 2008..Thus, it seems that hormones in females play a major role in the regulation of sleep and arousal via activation of neurons in key sleep and arousal centers...
- Estradiol differentially regulates lipocalin-type prostaglandin D synthase transcript levels in the rodent brain: Evidence from high-density oligonucleotide arrays and in situ hybridizationJessica A Mong
Laboratory of Neurobiology and Behavior, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
Proc Natl Acad Sci U S A 100:318-23. 2003....
- Estrogenic regulation of gene and protein expression within the amygdala of female miceAaron M Jasnow
Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
Endocrine 32:271-9. 2007..However, CaMKII protein levels were not different, and CaMKIV protein levels increased 2 h post-EB treatment. These results indicate that estrogen regulates CaMK gene expression and protein levels within the amygdala...
- Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormonesJessica A Mong
Department of Pharmacology and Experimental Therapeutics and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201 1559, USA
J Neurosci 31:16107-16. 2011..This a summary of recent work illustrating how sex differences and gonadal hormones influence sleep and circadian rhythms that was presented at a Mini-Symposium at the 2011 annual meeting of the Society for Neuroscience...
- Hormonal modulation of amino acid neurotransmitter metabolism in the arcuate nucleus of the adult female rat: a novel action of estradiolTamara Blutstein
Program in Neuroscience, University of Maryland School of Medicine, 655 West Baltimore Street, BRB 4 027, Baltimore, Maryland 21201, USA
Endocrinology 150:3237-44. 2009....
- Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female miceElena Choleris
Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY 10021, USA
Proc Natl Acad Sci U S A 104:4670-5. 2007..Understanding the functional genomics of OT and OTR in social recognition should help elucidate the neurobiological bases of human disorders of social behavior (e.g., autism)...
- Differential responses of hippocampal neurons and astrocytes to nicotine and hypoxia in the fetal guinea pigTamara Blutstein
Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA
Neurotox Res 24:80-93. 2013..Moreover, these effects most likely take place through distinct mechanisms...
- Hormonal and genetic influences underlying arousal as it drives sex and aggression in animal and human brainsJessica A Mong
The Laboratory of Neurobiology and Behavior, The Rockefeller University, 1230 York Avenue, Box 275, New York, NY 10021, USA
Neurobiol Aging 24:S83-8; discussion S91-2. 2003..With respect to aggression, besides testosterone and its metabolites, serotonergic projections to the forebrain play an important role...
- Gonadal steroid modulation of sleep and wakefulness in male and female rats is sexually differentiated and neonatally organized by steroid exposureDanielle M Cusmano
Program in Neuroscience D M C, J A M and Department of Pharmacology D M C, M M H, J A M, University of Maryland School of Medicine, Baltimore, Maryland 21201 and Department of Psychology M M H, University of Nicosia, 1700 Nicosia, Cyprus
Endocrinology 155:204-14. 2014..Together our data suggest that, like sex behavior, sex differences in sleep follow the classical organizational/activational effects of gonadal steroids. ..
- Estradiol modulates recovery of REM sleep in a time-of-day-dependent mannerMichael D Schwartz
Center for Neuroscience, Biosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA
Am J Physiol Regul Integr Comp Physiol 305:R271-80. 2013..These strong temporally dependent effects suggest that EB consolidates circadian sleep-wake rhythms in female rats. ..