L P Middleton

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Second-opinion pathologic review is a patient safety mechanism that helps reduce error and decrease waste
    Lavinia P Middleton
    University of Texas MD Anderson Cancer Center, Houston, TX
    J Oncol Pract 10:275-80. 2014
  2. doi request reprint Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the nu
    Lavinia P Middleton
    Departments of Pathology, The University of Texas M D Anderson Cancer Center, Houston, USA
    Arch Pathol Lab Med 133:775-80. 2009
  3. ncbi request reprint Expression of ERalpha and ERbeta in lobular carcinoma in situ
    L P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 50:875-80. 2007
  4. ncbi request reprint Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, PO Box 85, Houston, TX 77030, USA
    Cancer 98:1055-60. 2003
  5. ncbi request reprint Lobular carcinoma in situ diagnosed by core needle biopsy: when should it be excised?
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Mod Pathol 16:120-9. 2003
  6. ncbi request reprint Histopathology of breast cancer among African-American women
    Lavinia P Middleton
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:253-7. 2003
  7. doi request reprint Neovascularization in mucinous ductal carcinoma in situ suggests an alternative pathway for invasion
    S A Gadre
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 53:545-53. 2008
  8. ncbi request reprint Metastases to breast simulating ductal carcinoma in situ: report of two cases and review of the literature
    D Gupta
    Department of Pathology and Laboratory Medicine, University of Texas-Houston Medical School, Houston, TX 77030-1501, USA
    Ann Diagn Pathol 5:15-20. 2001
  9. ncbi request reprint Loss of myoepithelium is variable in solid papillary carcinoma of the breast
    M M Nicolas
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Histopathology 51:657-65. 2007
  10. ncbi request reprint Treatment and outcome of patients with intracystic papillary carcinoma of the breast
    Carmen C Solorzano
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg 184:364-8. 2002

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Second-opinion pathologic review is a patient safety mechanism that helps reduce error and decrease waste
    Lavinia P Middleton
    University of Texas MD Anderson Cancer Center, Houston, TX
    J Oncol Pract 10:275-80. 2014
    ..Our study examined the diagnostic error rate among patients with cancer treated at a tertiary care hospital and demonstrated the value of subspecialty pathologic review before initiation of treatment...
  2. doi request reprint Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the nu
    Lavinia P Middleton
    Departments of Pathology, The University of Texas M D Anderson Cancer Center, Houston, USA
    Arch Pathol Lab Med 133:775-80. 2009
    ..The American Society of Clinical Oncology/ College of American Pathologists (ASCO/CAP) guideline recommendations from January 2007 identified many sources of immunohistochemistry (IHC) testing variation...
  3. ncbi request reprint Expression of ERalpha and ERbeta in lobular carcinoma in situ
    L P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 50:875-80. 2007
    ..The aim of this study was to examine ER expression in LCIS to determine the relationship of ERalpha to ERbeta and, thereby, to determine whether it is of clinical value to measure ERbeta along with ERalpha...
  4. ncbi request reprint Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, PO Box 85, Houston, TX 77030, USA
    Cancer 98:1055-60. 2003
    ..However, very few contemporary studies have attempted to identify the combined histopathologic and immunohistochemical features of breast carcinoma in these patients...
  5. ncbi request reprint Lobular carcinoma in situ diagnosed by core needle biopsy: when should it be excised?
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Mod Pathol 16:120-9. 2003
    ..Based on these findings, we recommend excisional biopsy of lobular carcinoma in situ, atypical lobular hyperplasia or lobular neoplasia only when it is associated with a synchronous mass lesion...
  6. ncbi request reprint Histopathology of breast cancer among African-American women
    Lavinia P Middleton
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:253-7. 2003
    ..Furthermore, there is a need for central pathology review using accepted, published criteria for diagnosis of uncommon and controversial histologic subtypes of breast cancer...
  7. doi request reprint Neovascularization in mucinous ductal carcinoma in situ suggests an alternative pathway for invasion
    S A Gadre
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 53:545-53. 2008
    ..The aim was to characterize mucinous DCIS (mDCIS) of the breast and to describe, to our knowledge for the first time, neovascularization in mucin...
  8. ncbi request reprint Metastases to breast simulating ductal carcinoma in situ: report of two cases and review of the literature
    D Gupta
    Department of Pathology and Laboratory Medicine, University of Texas-Houston Medical School, Houston, TX 77030-1501, USA
    Ann Diagn Pathol 5:15-20. 2001
    ..When there is any unusual histomorphology, a good degree of suspicion is necessary. Ann Diagn Pathol 5:15-20, 2001...
  9. ncbi request reprint Loss of myoepithelium is variable in solid papillary carcinoma of the breast
    M M Nicolas
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Histopathology 51:657-65. 2007
    ..The aim was to clarify the frequency of myoepithelial loss in cases of SPC diagnosed at our institution...
  10. ncbi request reprint Treatment and outcome of patients with intracystic papillary carcinoma of the breast
    Carmen C Solorzano
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg 184:364-8. 2002
    ..Intracystic papillary carcinoma (IPC) of the breast is a rare form of noninvasive breast cancer. An appreciation of associated pathology with IPC may be critical in surgical decision-making...
  11. ncbi request reprint HER-2/neu and p53 overexpression as biomarkers of breast carcinoma in women age 30 years and younger
    Dipen Maru
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:900-5. 2005
    ..Although p53 and HER-2/neu overexpression are found in 30% of breast carcinomas in women of all ages and are associated with high rates of lymph node metastases, their role in women age < 30 years has not been studied extensively...
  12. ncbi request reprint Clinical outcome of patients with lymph node-negative breast carcinoma who have sentinel lymph node micrometastases detected by immunohistochemistry
    Anees Chagpar
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:1581-6. 2005
    ....
  13. ncbi request reprint Adjuvant systemic therapy for male breast carcinoma
    Sharon H Giordano
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:2359-64. 2005
    ..In the current study, the authors describe the M. D. Anderson experience with adjuvant systemic therapy in male breast carcinoma patients...
  14. pmc Accuracy of physical examination, ultrasonography, and mammography in predicting residual pathologic tumor size in patients treated with neoadjuvant chemotherapy
    Anees B Chagpar
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4095, USA
    Ann Surg 243:257-64. 2006
    ..To assess the accuracy of physical examination, ultrasonography, and mammography in predicting residual size of breast tumors following neoadjuvant chemotherapy...
  15. ncbi request reprint Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma
    Jianzhou Wang
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 94:3107-14. 2002
    ..In this study, the authors investigated the roles of tumor nuclear grade, mitotic activity, and biomarker expression profiles in predicting the pathologic response of breast tumors to preoperative chemotherapy...
  16. ncbi request reprint Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast
    Judy C Boughey
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1400 Holcombe Blvd, Houston, TX 77030, USA
    Am J Surg 194:450-5. 2007
    ..Whether it similarly limits lymph node staging by ultrasound (US) and fine-needle aspiration (FNA) biopsy was the subject of the current study...
  17. doi request reprint IGFBP2 and IGFBP5 overexpression correlates with the lymph node metastasis in T1 breast carcinomas
    Huamin Wang
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Breast J 14:261-7. 2008
    ..Our data suggest that IGFBP2 and IGFBP5 play a role in the development of metastasis and may serve as useful markers to predict lymph node metastasis in patients with small (T1) invasive breast carcinomas...
  18. ncbi request reprint E-cadherin immunohistochemical analysis of histiocytoid carcinoma of the breast
    Deepali Gupta
    Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, TX, USA
    Ann Diagn Pathol 6:141-7. 2002
    ..Moreover, the lack of consistent morphologic features, a specific clinical profile, and a distinct immunohistochemical pattern lead us to hypothesize that histiocytoid carcinoma is not a special type of breast cancer...
  19. ncbi request reprint Multicentric mammary carcinoma: evidence of monoclonal proliferation
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer 94:1910-6. 2002
    ..We also compared the clinical outcomes of the patients in the current study with stage-matched and treatment-matched groups of patients with unicentric mammary carcinoma...
  20. ncbi request reprint Intracystic papillary carcinoma of the breast with invasion
    A Elizabeth Wagner
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 57, Houston, TX 77030, USA
    AJR Am J Roentgenol 183:1516. 2004
  21. ncbi request reprint Invasive micropapillary carcinoma of the breast metastatic to the urinary bladder and endometrium: diagnostic pitfalls and review of the literature of tumors with micropapillary features
    Preetha Ramalingam
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Ann Diagn Pathol 7:112-9. 2003
    ..Carcinomas with micropapillary features have a propensity for lymph node metastases and advanced stage disease. This article discusses the differential diagnosis of carcinomas with micropapillary features in different organs...
  22. ncbi request reprint Clinical, histopathologic, and biologic features of pleomorphic lobular (ductal-lobular) carcinoma in situ of the breast: a report of 24 cases
    Nour Sneige
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mod Pathol 15:1044-50. 2002
    ..Long-term follow-up studies are needed to further define the natural history of PL/DLCIS and its optimal management...
  23. ncbi request reprint Comparison of fluorescence and chromogenic in situ hybridization for detection of HER-2/neu oncogene in breast cancer
    Deepali Gupta
    Department of Pathology, University of Texas Medical School, Houston, USA
    Am J Clin Pathol 119:381-7. 2003
    ..If a probe for chromosome 17 (now available for CISH) is used in cases of questionable HER-2/neu amplification, CISH seems to be as accurate and more practical than FISH...
  24. ncbi request reprint Accuracy of core needle biopsy diagnosis in assessing papillary breast lesions: histologic predictors of malignancy
    Doina Ivan
    Department of Pathology, The University of Texas Houston, Houston, TX, USA
    Mod Pathol 17:165-71. 2004
    ..0001) than is the presence of mitoses (P<0.053). A diagnosis of carcinoma or atypical papilloma by CNB should warrant an EB, whereas benign papillomas may be followed if imaging findings are concordant...
  25. ncbi request reprint Myolipoma of the breast: mammographic, sonographic, and pathologic correlation
    David K McGregor
    Department of Pathology, University of Texas, M D Anderson Cancer Center, Houston, Texas 77030 5816, USA
    Breast J 10:259-60. 2004
  26. ncbi request reprint Diagnostic pitfalls in fine needle aspiration cytology of atypical apocrine metaplasia in a breast lesion. A case report
    Deepali Gupta
    Department of Pathology and Laboratory Medicine, University of Texas Houston Medical School, Department of Pathology, M D Anderson Cancer Center, Houston, Texas, USA
    Acta Cytol 46:749-52. 2002
    ..Atypical apocrine metaplastic cells with signet ring features can also occur, and their presence may present a diagnostic dilemma in the differentiation of benign versus malignant lesions...
  27. ncbi request reprint Expression of c-kit proto-oncogene product in breast tissue
    Marwan A Yared
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Breast J 10:323-7. 2004
    ..These data suggest that c-kit may play a role in breast tumor progression and may therefore have diagnostic, prognostic, and therapeutic implications...
  28. ncbi request reprint Role of sonography in diagnosing and staging invasive lobular carcinoma
    Veronica L Selinko
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Unit 57, 1515 Holcombe Boulevard, Houston, Texas 77030 4009, USA
    J Clin Ultrasound 32:323-32. 2004
    ....
  29. ncbi request reprint Histologic localization of sentinel lymph node metastases in breast cancer
    Leslie K Diaz
    Department of Pathology, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 27:385-9. 2003
    ..This information may be useful in determining the optimal method for evaluating axillary sentinel lymph node specimens from breast cancer patients...
  30. ncbi request reprint Lymphoepithelioma-like carcinoma of the breast: report of a case mimicking lymphoma
    Souzan Sanati
    The University of Texas Medical Branch, Galveston, TX 77030 4009, USA
    Ann Diagn Pathol 8:309-15. 2004
    ..In summary, lymphoepithelioma-like carcinoma of the breast is a tumor with a good prognosis that should be considered as a possible diagnosis in breast tumors with an intense lymphocytic infiltrate...
  31. ncbi request reprint Intracystic papillary carcinoma of the breast
    Basak Erguvan Dogan
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 57, Houston, TX 77030, USA
    AJR Am J Roentgenol 181:186. 2003
  32. pmc Breast cancer in men
    George H Perkins
    BMJ 327:239-40. 2003
  33. ncbi request reprint Specimen radiography in confirmation of MRI-guided needle localization and surgical excision of breast lesions
    Basak Erguvan-Dogan
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1350, Houston, TX 77230, USA
    AJR Am J Roentgenol 187:339-44. 2006
    ..The aim of this study was to determine the feasibility of using specimen radiography to verify lesion removal after MRI-guided needle localization and surgical excision...
  34. ncbi request reprint Serous carcinoma of the ovary and peritoneum with metastases to the breast and axillary lymph nodes: a potential pitfall
    Monica A Recine
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 28:1646-51. 2004
    ..Clinical history, the presence of papillary architecture, and WT-1 expression are useful in establishing the correct diagnosis...
  35. ncbi request reprint Factors predictive of having four or more positive axillary lymph nodes in patients with positive sentinel lymph nodes: implications for selection of radiation fields
    Karen H Shahar
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 97, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:1074-9. 2004
    ..To determine the optimal arrangement for patients with positive SLNs, we studied what factors predicted for having four or more positive lymph nodes...