Research Topics
| P T MaruchaSummaryAffiliation: The Ohio State University Country: USA Publications
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Detail Information
Publications
Mucosal wound healing is impaired by examination stressP T Marucha
Section of Periodontology, College of Dentistry, The Ohio State University, Columbus, USA
Psychosom Med 60:362-5. 1998..There is also growing evidence that psychological stress has adverse consequences for immune function. This study addressed the effects of a commonplace stressor on wound healing...- Hypnosis as a modulator of cellular immune dysregulation during acute stressJ K Kiecolt-Glaser
Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210, USA
J Consult Clin Psychol 69:674-82. 2001..These data provide encouraging evidence that interventions may reduce the immunological dysregulation associated with acute stressors... - Experimental models of stress and wound healingJohn F Sheridan
Section of Oral Biology, Ohio State University, 305 W 12th Avenue, Columbus, OH 43218 2357, USA
World J Surg 28:327-30. 2004..RST slowed wound healing in inbred C57BL/6 mice, whereas the wounds on SDR mice healed in a fashion similar to the non-stressed, home cage controls... 
Ala42S100A8 ameliorates psychological-stress impaired cutaneous wound healingHerve Y Sroussi
Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois at Chicago, 801 S Paulina St, Chicago, IL 60612 7213, USA
Brain Behav Immun 23:755-9. 2009..Wild-type S100A8 only had a partial beneficial effect on the rate of wound closure. Those findings support further translational studies of S100 based intervention to ameliorate impaired wound healing...- Altered kinetics of IL-1 alpha, IL-1 beta, and KGF-1 gene expression in early wounds of restrained miceAna M Mercado
Department of Oral Biology, College of Dentistry, The Ohio State University, Columbus, 43210, USA
Brain Behav Immun 16:150-62. 2002..Our results suggest that stress induces alterations in the kinetics of cutaneous proinflammatory cytokine and growth factor gene expression which could impair the quality of healing tissues... - Stress-related changes in proinflammatory cytokine production in woundsR Glaser
Department of Medical Microbiology, The Institute for Behavioral Medicine Research, The Ohio State University, Columbus 43210, USA
Arch Gen Psychiatry 56:450-6. 1999.... - Stress-induced susceptibility to bacterial infection during cutaneous wound healingIsolde-Gina Rojas
Department of Oral Biology, College of Dentistry, The Ohio State University, Columbus 43210, USA
Brain Behav Immun 16:74-84. 2002..RU486 reduced opportunistic bacteria by nearly 1 log in wounds from RST mice (p <.05). Thus, stress impairs bacterial clearance during wound healing, resulting in a significant increase in the incidence of opportunistic infection... - Hyperbaric oxygen therapy ameliorates stress-impaired dermal wound healingPraveen K Gajendrareddy
Department of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 19:217-22. 2005..Our current findings represent the first experimental evidence, demonstrating that HBO corrects stress-impaired dermal wound healing... - Impaired wound contraction and delayed myofibroblast differentiation in restraint-stressed miceMichael P Horan
Department of Oral Biology, The Ohio State University, Columbus, OH 43218-2357, USA
Brain Behav Immun 19:207-16. 2005..Thus, these data indicate that stress delays wound contraction and myofibroblast differentiation, which are likely independent of expression of TGF-beta1, -beta2, and -beta3... - Acute stress evokes selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular diseaseJos A Bosch
Periodontology Section, The Ohio State University, College of Dentistry, 305 West 12th Avenue, P.O. Box 182357, Columbus, OH 43218, USA
Brain Behav Immun 17:251-9. 2003..This mechanism may help explain the link between stress, reactivity, and cardiovascular disease... - Restraint stress alters the expression of interleukin-1 and keratinocyte growth factor at the wound site: an in situ hybridization studyAna M Mercado
Department of Oral Biology, The Ohio State University, Columbus, OH 43210, USA
J Neuroimmunol 129:74-83. 2002..Therefore, stress-induced alterations in cutaneous proinflammatory cytokine and growth factor expression are associated with significant histological changes in healing wounds... - Depressive symptoms predict mucosal wound healingJos A Bosch
University of Illinois at Chicago, College of Dentistry, Chicago, IL 60612, USA
Psychosom Med 69:597-605. 2007..Feelings of depression and social isolation are common among surgical patients, and the present study therefore investigated if these factors predict the rate of mucosal wound healing... - Social stress increases the susceptibility to endotoxic shockN Quan
Section of Oral Biology, The Ohio State University Health Science Center, Columbus, OH 43210, USA
J Neuroimmunol 115:36-45. 2001.... - Sex hormones and mucosal wound healingChristopher G Engeland
Department of Periodontics, University of Illinois at Chicago, College of Dentistry, Chicago, IL 60612, USA
Brain Behav Immun 23:629-35. 2009..Based upon when between-group differences were observed, testosterone may impact upon the proliferative phase of healing which involves immune processes such as re-epithelialization and angiogenesis... 
HIV infection and tooth lossChristopher G Engeland
Department of Periodontics, University of Illinois at Chicago, College of Dentistry, Chicago, Illinois 60612, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:321-6. 2008..The objective of this study was to determine the relationship between HIV infection and tooth loss. Based on periodontal reports, we hypothesize HIV+ patients experience greater tooth loss than systemically healthy patients...- Differential mobilization of functionally distinct natural killer subsets during acute psychologic stressJos A Bosch
University of Illinois at Chicago, College of Dentistry, Chicago, IL 60611, USA
Psychosom Med 67:366-75. 2005..CONCLUSION: The marked specificity and robustness of these effects support the idea that NK cell mobilization is a functionally relevant response that is aimed at protecting the organism during acutely stressful situations... - The influence of a structured telephone call on orthodontic pain and anxietyBrian W Bartlett
Section of Orthodontics, College of Dentistry, Ohio State University, Columbus, OH 43218-2357, USA
Am J Orthod Dentofacial Orthop 128:435-41. 2005..12 for pain; P > .81 for state-anxiety). CONCLUSIONS: A telephone call from a health-care provider reduced patients' self-reported pain and anxiety; the content of the telephone call was not important... - TNF-alpha levels in cancer patients relate to social variablesPhillip T Marucha
Department of Periodontics, College of Dentistry, University of Illinois at Chicago, USA
Brain Behav Immun 19:521-5. 2005..This is the first study to link changes in patient social relations with a cancer-relevant immune variable... - Stress-induced changes in pathophysiology and interferon gene expression during primary HSV-1 infectionGriselle C Ortiz
Department of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 17:329-38. 2003..Thus, RST masked the severity of an HSV-1 infection by decreasing its clinical signs while impairing the ability of the host to control viral replication prolonging the infectious period... - Restraint stress impairs early wound healing in mice via alpha-adrenergic but not beta-adrenergic receptorsNiels Eijkelkamp
Laboratory for Psychoneuroimmunology, University Medical Center Utrecht, Utrecht, The Netherlands
Brain Behav Immun 21:409-12. 2007..Thus, although stress impairment in wound healing clearly involves GCs, catecholamines play an important role via alpha-adrenergic receptor stimulation... - Stress decreases, while central nucleus amygdala lesions increase, IL-8 and MIP-1alpha gene expression during tissue healing in non-human primatesNed H Kalin
Department of Psychiatry, University of Wisconsin, Madison, WI 53719, USA
Brain Behav Immun 20:564-8. 2006..Because of brain and behavioral similarities between rhesus monkeys and humans, these results are particularly relevant to understanding brain mechanisms that influence healing in humans... - Mucosal wound healing: the roles of age and sexChristopher G Engeland
Department of Periodontics, University of Illinois at Chicago, 801 S. Paulina Street, Chicago, IL 60612, USA
Arch Surg 141:1193-7; discussion 1198. 2006..These findings may help target patients with increased surgical risks and greater need for postsurgical care...