Amy B Manning-Bog

Summary

Affiliation: The Parkinson's Institute
Country: USA

Publications

  1. ncbi Lack of nigrostriatal pathology in a rat model of proteasome inhibition
    Amy B Manning-Bog
    Department of Basic Research, The Parkinson s Institute, Sunnyvale, CA, USA
    Ann Neurol 60:256-60. 2006
  2. ncbi Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter
    Amy B Manning-Bog
    Department of Basic Research, The Parkinson s Institute, 1170 Morse Avenue, Sunnyvale, CA 94089, USA
    Neurobiol Dis 27:141-50. 2007
  3. doi Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: a biological link between Gaucher disease and parkinsonism
    Amy B Manning-Bog
    The Parkinson s Institute, 675 Almanor Ave, Sunnyvale, CA 94085, USA
    Neurotoxicology 30:1127-32. 2009
  4. ncbi Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
    Alison L McCormack
    The Parkinson s Institute, Sunnyvale, California 94089, USA
    Neurobiol Dis 10:119-27. 2002
  5. ncbi Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration
    Amy B Manning-Bog
    The Parkinson s Institute, Sunnyvale, California 94089 1605, USA
    J Neurosci 23:3095-9. 2003
  6. pmc Lysosomal degradation of alpha-synuclein in vivo
    Sally K Mak
    The Parkinson s Institute, Sunnyvale, California 94085, USA
    J Biol Chem 285:13621-9. 2010
  7. doi Evidence of oxidative stress in young and aged DJ-1-deficient mice
    Arjun V Raman
    The Parkinson s Institute, Department of Basic Research, Sunnyvale, CA, USA
    FEBS Lett 587:1562-70. 2013
  8. ncbi Environmental factors in Parkinson's disease
    Donato A Di Monte
    The Parkinson s Institute, Sunnyvale, CA 94089 1605, USA
    Neurotoxicology 23:487-502. 2002
  9. ncbi Model fusion, the next phase in developing animal models for Parkinson's disease
    Amy B Manning-Bog
    The Parkinson s Institute, 1170 Morse Ave, Sunnyvale, CA 94089, USA
    Neurotox Res 11:219-40. 2007
  10. ncbi The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein
    Amy B Manning-Bog
    Parkinson s Institute, Sunnyvale, California 94089, USA
    J Biol Chem 277:1641-4. 2002

Detail Information

Publications10

  1. ncbi Lack of nigrostriatal pathology in a rat model of proteasome inhibition
    Amy B Manning-Bog
    Department of Basic Research, The Parkinson s Institute, Sunnyvale, CA, USA
    Ann Neurol 60:256-60. 2006
    ....
  2. ncbi Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter
    Amy B Manning-Bog
    Department of Basic Research, The Parkinson s Institute, 1170 Morse Avenue, Sunnyvale, CA 94089, USA
    Neurobiol Dis 27:141-50. 2007
    ..control striatum. Thus, under null DJ-1 conditions, DAT changes likely contribute to altered DA neurotransmission and enhanced sensitivity to toxins that utilize DAT for nigrostriatal entry...
  3. doi Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: a biological link between Gaucher disease and parkinsonism
    Amy B Manning-Bog
    The Parkinson s Institute, 675 Almanor Ave, Sunnyvale, CA 94085, USA
    Neurotoxicology 30:1127-32. 2009
    ....
  4. ncbi Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
    Alison L McCormack
    The Parkinson s Institute, Sunnyvale, California 94089, USA
    Neurobiol Dis 10:119-27. 2002
    ....
  5. ncbi Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration
    Amy B Manning-Bog
    The Parkinson s Institute, Sunnyvale, California 94089 1605, USA
    J Neurosci 23:3095-9. 2003
    ....
  6. pmc Lysosomal degradation of alpha-synuclein in vivo
    Sally K Mak
    The Parkinson s Institute, Sunnyvale, California 94085, USA
    J Biol Chem 285:13621-9. 2010
    ..It is conceivable that these neuronal mechanisms of protein clearance play an important role in neurodegenerative processes characterized by abnormal alpha-synuclein buildup...
  7. doi Evidence of oxidative stress in young and aged DJ-1-deficient mice
    Arjun V Raman
    The Parkinson s Institute, Department of Basic Research, Sunnyvale, CA, USA
    FEBS Lett 587:1562-70. 2013
    ..These changes were concomitant with increased striatal dopamine levels and uptake. Thus, increased oxidants and diminished protein quality control may contribute to nigral oxidative damage with aging in the model...
  8. ncbi Environmental factors in Parkinson's disease
    Donato A Di Monte
    The Parkinson s Institute, Sunnyvale, CA 94089 1605, USA
    Neurotoxicology 23:487-502. 2002
    ..g. the protein alpha-synuclein); (iii) the tissue response to an initial toxic insult; and, last but not least, (iv) the effects of environmental factors on the background of genetic predisposition and aging...
  9. ncbi Model fusion, the next phase in developing animal models for Parkinson's disease
    Amy B Manning-Bog
    The Parkinson s Institute, 1170 Morse Ave, Sunnyvale, CA 94089, USA
    Neurotox Res 11:219-40. 2007
    ....
  10. ncbi The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein
    Amy B Manning-Bog
    Parkinson s Institute, Sunnyvale, California 94089, USA
    J Biol Chem 277:1641-4. 2002
    ....