THOMAS MAGLIERY

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Sequence variation in ligand binding sites in proteins
    Thomas J Magliery
    Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208114, New Haven, CT 06520 8114, USA
    BMC Bioinformatics 6:240. 2005
  2. pmc Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems
    Thomas J Magliery
    Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA
    Curr Opin Chem Biol 15:443-51. 2011
  3. ncbi request reprint Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif
    Thomas J Magliery
    Department of Molecular Biophysics and Biochemistry, Yale University, P O Box 208114, New Haven, CT 06520 8114, USA
    J Mol Biol 343:731-45. 2004

Collaborators

Detail Information

Publications3

  1. pmc Sequence variation in ligand binding sites in proteins
    Thomas J Magliery
    Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208114, New Haven, CT 06520 8114, USA
    BMC Bioinformatics 6:240. 2005
    ..In contrast, little attention has been given to the meaning of poorly-conserved sites in families of proteins, which are typically assumed to be of little structural or functional importance...
  2. pmc Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems
    Thomas J Magliery
    Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA
    Curr Opin Chem Biol 15:443-51. 2011
    ..Protein engineering based on statistical analysis (consensus and correlated occurrences of amino acids) is promising, but much work remains to understand and implement these methods...
  3. ncbi request reprint Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif
    Thomas J Magliery
    Department of Molecular Biophysics and Biochemistry, Yale University, P O Box 208114, New Haven, CT 06520 8114, USA
    J Mol Biol 343:731-45. 2004
    ..Statistical free energy analysis provides a more complete description of "What makes a TPR a TPR?" than consensus alone, and it suggests general approaches to extend and improve the phylogenetic design of proteins...

Research Grants5

  1. Combinatorial approaches to protein folding and function
    THOMAS MAGLIERY; Fiscal Year: 2004
    ..A screen for Rop function will allow us to radically expand the scope of protein redesign and refine our understanding of the parameters that control protein folding and stability. ..
  2. Combinatorial biophysics: understanding protein stability with library approaches
    THOMAS MAGLIERY; Fiscal Year: 2009
    ....
  3. Combinatorial biophysics: understanding protein stability with library approaches
    Thomas J Magliery; Fiscal Year: 2010
    ....
  4. Combinatorial biophysics: understanding protein stability with library approaches
    THOMAS MAGLIERY; Fiscal Year: 2009
    ....