IAN JOHN MACRAE

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. pmc In vitro reconstitution of the human RISC-loading complex
    Ian J Macrae
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 105:512-7. 2008

Research Grants

  1. Structure and Mechanism of the RISC-loading Complex
    IAN JOHN MACRAE; Fiscal Year: 2010
  2. Structure and Mechanism of the RISC-loading Complex
    IAN JOHN MACRAE; Fiscal Year: 2011

Collaborators

Detail Information

Publications1

  1. pmc In vitro reconstitution of the human RISC-loading complex
    Ian J Macrae
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 105:512-7. 2008
    ..Furthermore, once Ago2 is loaded with an miRNA, it tends to dissociate from the rest of the complex. These results lay the groundwork for future structural and functional dissection of RISC loading in humans...

Research Grants4

  1. Structure and Mechanism of the RISC-loading Complex
    IAN JOHN MACRAE; Fiscal Year: 2010
    ..Results will contribute to on-going efforts to harness the RNAi process as a powerful new type of therapeutic for the treatment of human disease. ..
  2. Structure and Mechanism of the RISC-loading Complex
    IAN JOHN MACRAE; Fiscal Year: 2011
    ..Results will contribute to on-going efforts to harness the RNAi process as a powerful new type of therapeutic for the treatment of human disease. ..