Gary Lu

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Plasma cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients with plasma cell neoplasms
    Gary Lu
    Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Arch Pathol Lab Med 137:625-31. 2013
  2. doi request reprint Deletion 15q as the sole abnormality in acute myeloid leukemia: report of three cases and review of the literature
    Gary Lu
    Department of Hematopathology, Box 350, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer Genet Cytogenet 188:118-23. 2009
  3. doi request reprint Correlation of assessment of plasma cells by flow cytometry and detection of cytogenomic abnormalities by fluorescence in situ hybridization in plasma cell neoplasms
    G Lu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Lab Hematol 33:545-50. 2011
  4. doi request reprint Genetic and immunophenotypic profile of IGH@ rearrangement detected by fluorescence in situ hybridization in 149 cases of B-cell chronic lymphocytic leukemia
    Gary Lu
    Department of Hematopathology, Box 350, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer Genet Cytogenet 196:56-63. 2010
  5. ncbi request reprint t(10; 12) (q24; p13) as the sole abnormality in a case with refractory acute myeloid leukemia: The first case report and literature review
    Gary Lu
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Beijing Da Xue Xue Bao 41:480-3. 2009
  6. doi request reprint Therapy-related myeloid neoplasms with isolated del(20q): comparison with cases of de novo myelodysplastic syndrome with del(20q)
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Cancer Genet 206:42-6. 2013
  7. pmc Trisomy 14 as a sole chromosome abnormality is associated with older age, a heterogenous group of myeloid neoplasms with dysplasia, and a wide spectrum of disease progression
    Wei Cui
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Bouleuard, Houston, TX 77030, USA
    J Biomed Biotechnol 2010:365318. 2010
  8. doi request reprint Chromosome 20q deletion: a recurrent cytogenetic abnormality in patients with chronic myelogenous leukemia in remission
    Jianlan Sun
    Dept of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Am J Clin Pathol 135:391-7. 2011
  9. doi request reprint High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 61:945-54. 2012
  10. doi request reprint Myeloid neoplasms with isolated isochromosome 17q represent a clinicopathologic entity associated with myelodysplastic/myeloproliferative features, a high risk of leukemic transformation, and wild-type TP53
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 118:2879-88. 2012

Collaborators

Detail Information

Publications17

  1. doi request reprint Plasma cell enrichment enhances detection of high-risk cytogenomic abnormalities by fluorescence in situ hybridization and improves risk stratification of patients with plasma cell neoplasms
    Gary Lu
    Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Arch Pathol Lab Med 137:625-31. 2013
    ..There are no published reports using these methods to evaluate high-risk cytogenomic abnormalities in patients with plasma cell neoplasms (PCNs) after therapy...
  2. doi request reprint Deletion 15q as the sole abnormality in acute myeloid leukemia: report of three cases and review of the literature
    Gary Lu
    Department of Hematopathology, Box 350, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer Genet Cytogenet 188:118-23. 2009
    ..These cases often show features of myelomonocytic or monocytic differentiation. The prognosis is poor, with survival similar to other AML cases with unfavorable cytogenetic changes...
  3. doi request reprint Correlation of assessment of plasma cells by flow cytometry and detection of cytogenomic abnormalities by fluorescence in situ hybridization in plasma cell neoplasms
    G Lu
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Lab Hematol 33:545-50. 2011
    ..However, correlation of FC-assessed PCs with FISH-detected CAs has not been well studied. The purpose of this study was to validate this correlation on BM aspirates from patients with PCN...
  4. doi request reprint Genetic and immunophenotypic profile of IGH@ rearrangement detected by fluorescence in situ hybridization in 149 cases of B-cell chronic lymphocytic leukemia
    Gary Lu
    Department of Hematopathology, Box 350, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer Genet Cytogenet 196:56-63. 2010
    ..It is appropriate to include an IGH@ probe in the FISH panel for B-CLL diagnosis...
  5. ncbi request reprint t(10; 12) (q24; p13) as the sole abnormality in a case with refractory acute myeloid leukemia: The first case report and literature review
    Gary Lu
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Beijing Da Xue Xue Bao 41:480-3. 2009
    ..Complete laboratory findings from bone marrow examination, flow cytometry analysis, cytogenetic studies, molecular analysis, and clinical features are also described in the report...
  6. doi request reprint Therapy-related myeloid neoplasms with isolated del(20q): comparison with cases of de novo myelodysplastic syndrome with del(20q)
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Cancer Genet 206:42-6. 2013
    ..The median overall survival was 64 months. In all cases, del(20q) was present at the time of diagnosis...
  7. pmc Trisomy 14 as a sole chromosome abnormality is associated with older age, a heterogenous group of myeloid neoplasms with dysplasia, and a wide spectrum of disease progression
    Wei Cui
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Bouleuard, Houston, TX 77030, USA
    J Biomed Biotechnol 2010:365318. 2010
    ..Compared with cases of MDS with diploid karyotype, patients of MDS with isolated trisomy 14 demonstrate a similar overall survival and rate of leukemia transformation...
  8. doi request reprint Chromosome 20q deletion: a recurrent cytogenetic abnormality in patients with chronic myelogenous leukemia in remission
    Jianlan Sun
    Dept of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Am J Clin Pathol 135:391-7. 2011
    ..01%). Recently, in 1 patient, recurrent CML developed and del(20q) was lost. We conclude that del(20q) in the setting of CML in remission is not predictive of MDS or blast transformation...
  9. doi request reprint High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearrangements and a poor prognosis
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Histopathology 61:945-54. 2012
    ..At a haematopathology workshop, experts had suggested the term 'high-grade B cell lymphoma, unclassifiable, with blastoid features', and recommended further studies...
  10. doi request reprint Myeloid neoplasms with isolated isochromosome 17q represent a clinicopathologic entity associated with myelodysplastic/myeloproliferative features, a high risk of leukemic transformation, and wild-type TP53
    Rashmi Kanagal-Shamanna
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 118:2879-88. 2012
    ..De novo acute myeloid leukemia (AML) with isochromosome 17q has rarely been reported. The frequency of genetic mutations is unknown...
  11. doi request reprint Myelodysplastic syndrome/acute myeloid leukemia with t(3;21)(q26.2;q22) is commonly a therapy-related disease associated with poor outcome
    Shaoying Li
    Department of Hematopathology, Unit 72, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Pathol 138:146-52. 2012
    ....
  12. doi request reprint Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia
    Sergej Konoplev
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Leuk Lymphoma 54:138-44. 2013
    ..All cases of Ph+ AML were negative for ABL1 and other gene mutations. One (20%) patient with CML-BP had ABL1 mutation; no patients had NPM1 mutations. These data suggest that Ph+ AML is distinct from CML-BP...
  13. doi request reprint Molecular and clinicopathologic characterization of AML with isolated trisomy 4
    Ashish Bains
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Clin Pathol 137:387-94. 2012
    ..Median overall survival was 28 months. AML with isolated trisomy 4 is rare and associated with high bone marrow blast counts and an intermediate to poor prognosis. KIT mutations are uncommon...
  14. doi request reprint Advances in the molecular pathobiology of B-lymphoblastic leukemia
    Yi Zhou
    Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Pathol 43:1347-62. 2012
    ....
  15. pmc Trisomy 11 as an isolated abnormality in acute myeloid leukemia is associated with unfavorable prognosis but not with an NPM1 or KIT mutation
    Faisal M Alseraye
    Department of Hematopathology, The University of Texas MD Anderson Cancer Center Houston, TX, USA
    Int J Clin Exp Pathol 4:371-7. 2011
    ..Our findings confirm previous reports that isolated +11 is associated with a poor prognosis in patients with AML and tends to be associated with FAB-M1 morphologic features. No evidence of NPM1 or KIT mutations were identified...
  16. doi request reprint del(15q) is a recurrent minor-route cytogenetic abnormality in the clonal evolution of chronic myelogenous leukemia
    C Cameron Yin
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Genet Cytogenet 192:18-23. 2009
    ..Del(15q) appears to be associated with a poor prognosis in CML...
  17. doi request reprint Plasmablastic lymphoma involving the penis: a previously unreported location of a case with aberrant CD3 expression
    Jianlan Sun
    Department of Hematopathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Pathology 43:54-7. 2011
    ..Lineage ambiguity in terminally differentiated B-cell lymphomas has been reported to be closely related with immune compromise and is associated with Epstein-Barr virus infection. The literature on penile lymphomas is also reviewed...