Andreas W Loepke

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs
    Andreas W Loepke
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Anesthesiology 97:1521-7. 2002
  2. ncbi request reprint Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets
    Dara Ditsworth
    Brain Research Laboratory, Department of Anesthesiology and Critical Care Medicine, The Joseph Stokes Jr Research Institute, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Anesthesiology 98:1119-27. 2003
  3. ncbi request reprint The plasma pharmacokinetics and cerebral spinal fluid penetration of intravenous topiramate in newborn pigs
    Jeffrey L Galinkin
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Biopharm Drug Dispos 25:265-71. 2004
  4. ncbi request reprint Injury pattern of the neonatal brain after hypothermic low-flow cardiopulmonary bypass in a piglet model
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Institute of Pediatric Anesthesia, Cincinnati Children s Hospital Research Foundation, Ohio 45229, USA
    Anesth Analg 101:340-8, table of contents. 2005
  5. ncbi request reprint The physiologic effects of isoflurane anesthesia in neonatal mice
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Anesth Analg 102:75-80. 2006
  6. doi request reprint An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, USA
    Anesth Analg 106:1681-707. 2008
  7. doi request reprint CON: The toxic effects of anesthetics in the developing brain: the clinical perspective
    Andreas W Loepke
    Anesth Analg 106:1664-9. 2008

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs
    Andreas W Loepke
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Anesthesiology 97:1521-7. 2002
    ..Desflurane confers neuroprotection against ischemia at normothermia and for DHCA. This study compared neurologic outcome of a desflurane-based with a fentanyl-based anesthetic for LF-CPB...
  2. ncbi request reprint Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets
    Dara Ditsworth
    Brain Research Laboratory, Department of Anesthesiology and Critical Care Medicine, The Joseph Stokes Jr Research Institute, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Anesthesiology 98:1119-27. 2003
    ..Caspases, cytochrome c, tumor necrosis factor (TNF), and Fas play a role in apoptosis in many ischemic models. This study examined the expression of these factors in a DHCA piglet model...
  3. ncbi request reprint The plasma pharmacokinetics and cerebral spinal fluid penetration of intravenous topiramate in newborn pigs
    Jeffrey L Galinkin
    Department of Anesthesiology and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Biopharm Drug Dispos 25:265-71. 2004
    ..The plasma pharmacokinetics, cerebrospinal fluid (CSF) penetration and pharmacodynamics of intravenous topiramate were studied in an established piglet model of hypoxia-ischemia...
  4. ncbi request reprint Injury pattern of the neonatal brain after hypothermic low-flow cardiopulmonary bypass in a piglet model
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Institute of Pediatric Anesthesia, Cincinnati Children s Hospital Research Foundation, Ohio 45229, USA
    Anesth Analg 101:340-8, table of contents. 2005
    ..Factors mitigating injury were higher arterial carbon dioxide, hematocrit, and blood glucose levels...
  5. ncbi request reprint The physiologic effects of isoflurane anesthesia in neonatal mice
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Anesth Analg 102:75-80. 2006
    ..Use of 0.8 MAC isoflurane for evaluation of neuroprotection during hypoxia-ischemia requires mechanical ventilation and glucose supplementation in this model...
  6. doi request reprint An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, USA
    Anesth Analg 106:1681-707. 2008
    ..In the present review, we assess the evidence for the effects of commonly used anesthetics on neuronal structure and neurocognitive function in newborn humans and animals...
  7. doi request reprint CON: The toxic effects of anesthetics in the developing brain: the clinical perspective
    Andreas W Loepke
    Anesth Analg 106:1664-9. 2008