M Lipkin

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Dietary factors in human colorectal cancer
    M Lipkin
    Strang Cancer Prevention Center, New York, USA
    Annu Rev Nutr 19:545-86. 1999
  2. ncbi request reprint Preclinical mouse models for cancer chemoprevention studies
    M Lipkin
    Strang Cancer Research Laboratory, Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 889:14-9. 1999
  3. ncbi request reprint Preclinical and early human studies of calcium and colon cancer prevention
    M Lipkin
    Strang Cancer Research Laboratory, Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 889:120-7. 1999
  4. ncbi request reprint Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis
    K Yang
    Strang Cancer Prevention Center and The New York Hospital Cornell Medical Center, New York 10021, USA
    Cancer Res 58:5713-7. 1998
  5. ncbi request reprint The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
    M Kuraguchi
    Strang Cancer Research Laboratory at The Rockefeller University, New York, New York 10021, USA
    Cancer Res 61:7934-42. 2001
  6. ncbi request reprint A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice
    H L Newmark
    Strang Cancer Prevention Center, New York, NY 10021, USA
    Carcinogenesis 22:1871-5. 2001
  7. ncbi request reprint Cellular mechanisms of calcium and vitamin D in the inhibition of colorectal carcinogenesis
    S A Lamprecht
    Strang Cancer Prevention Center, New York, NewYork 10021, USA
    Ann N Y Acad Sci 952:73-87. 2001
  8. ncbi request reprint Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency
    M Kuraguchi
    Strang Cancer Research Laboratory at The Rockefeller University, New York, NY 10021, USA
    Oncogene 19:5755-63. 2000
  9. ncbi request reprint Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice
    E Sehayek
    Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York, NY 10021, USA
    J Lipid Res 42:1250-6. 2001
  10. ncbi request reprint A mouse model of human familial adenomatous polyposis
    K Yang
    Strang Cancer Prevention Center, New York Hospital Cornell Medical Center, New York 10021, USA
    J Exp Zool 277:245-54. 1997

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Dietary factors in human colorectal cancer
    M Lipkin
    Strang Cancer Prevention Center, New York, USA
    Annu Rev Nutr 19:545-86. 1999
    ..We believe that continuing scrutiny and precise assessment of the benefits (and potential risks) of nutrients in the treatment and prevention of colorectal cancer will prove significant to controlling this devastating disease...
  2. ncbi request reprint Preclinical mouse models for cancer chemoprevention studies
    M Lipkin
    Strang Cancer Research Laboratory, Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 889:14-9. 1999
    ..These new preclinical models are assisting the analysis of genetic and environmental factors leading to neoplasia, and clinical studies to evaluate the chemopreventive efficacy of specific nutrients and pharmacological agents...
  3. ncbi request reprint Preclinical and early human studies of calcium and colon cancer prevention
    M Lipkin
    Strang Cancer Research Laboratory, Rockefeller University, New York, New York 10021, USA
    Ann N Y Acad Sci 889:120-7. 1999
    ..Many experimental findings described below have indicated associations between high calcium and vitamin D intake and decreased risk for colorectal cancer...
  4. ncbi request reprint Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis
    K Yang
    Strang Cancer Prevention Center and The New York Hospital Cornell Medical Center, New York 10021, USA
    Cancer Res 58:5713-7. 1998
    ..The findings therefore demonstrated dietary modulation of carcinoma incidence in mice with a targeted mutation providing a model for the study of gene-environment interactions in cancer...
  5. ncbi request reprint The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
    M Kuraguchi
    Strang Cancer Research Laboratory at The Rockefeller University, New York, New York 10021, USA
    Cancer Res 61:7934-42. 2001
    ..Our analysis therefore has revealed distinct mutational spectra and clarified the roles of Msh3 and Msh6 in DNA repair and intestinal tumorigenesis...
  6. ncbi request reprint A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice
    H L Newmark
    Strang Cancer Prevention Center, New York, NY 10021, USA
    Carcinogenesis 22:1871-5. 2001
    ..04 compared with AIN-76A diet). The results indicate, for the first time, that a semi-purified rodent diet designed to mimic the human Western diet can induce colonic tumors in normal mice without carcinogen exposure...
  7. ncbi request reprint Cellular mechanisms of calcium and vitamin D in the inhibition of colorectal carcinogenesis
    S A Lamprecht
    Strang Cancer Prevention Center, New York, NewYork 10021, USA
    Ann N Y Acad Sci 952:73-87. 2001
    ..These consist of complex series of signaling events induced by the chemopreventive agents acting at various tiers of colonic cell organization...
  8. ncbi request reprint Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency
    M Kuraguchi
    Strang Cancer Research Laboratory at The Rockefeller University, New York, NY 10021, USA
    Oncogene 19:5755-63. 2000
    ..This demonstrates a direct effect of Mlh1 deficiency in the mutation of Apc in these tumors, and provides data that clarify the role of Mlh1 in mammalian DNA mismatch repair...
  9. ncbi request reprint Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice
    E Sehayek
    Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York, NY 10021, USA
    J Lipid Res 42:1250-6. 2001
    ..These results suggest that HDCA might have beneficial effects in the treatment of increased plasma cholesterol levels and atherosclerosis...
  10. ncbi request reprint A mouse model of human familial adenomatous polyposis
    K Yang
    Strang Cancer Prevention Center, New York Hospital Cornell Medical Center, New York 10021, USA
    J Exp Zool 277:245-54. 1997
    ..These results suggest that mice carrying the Apc1638 mutation can serve as a good model to study the initiation, progression, and inhibition of gastrointestinal tumors...
  11. ncbi request reprint Comparison of calcium supplementation or low-fat dairy foods on epithelial cell proliferation and differentiation
    P R Holt
    Gastrointestinal Division, Department of Medicine, St. Luke's/Roosevelt Hospital Center and Columbia University, New York, NY, USA
    Nutr Cancer 41:150-5. 2001
    ..Because supplemental calcium has been shown to reduce the recurrence of colonic adenomatous polyps in patients at increased risk for colonic neoplasia, our data suggest that supplemental low-fat dairy foods may also be effective...