D Chichung Lie

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Neurogenesis in the adult brain: new strategies for central nervous system diseases
    D Chichung Lie
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037, USA
    Annu Rev Pharmacol Toxicol 44:399-421. 2004
  2. ncbi request reprint New regulators in adult neurogenesis and their potential role for repair
    Ravi Jagasia
    Institute of Developmental Genetics, GSF National Research Center for Environment and Health, 85764 Munich Neuherberg, Germany
    Trends Mol Med 12:400-5. 2006
  3. doi request reprint Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus
    Helena Mira
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Cell Stem Cell 7:78-89. 2010
  4. pmc Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus
    Sebastian Jessberger
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California, USA
    PLoS Biol 6:e272. 2008
  5. pmc Retinoic acid is required early during adult neurogenesis in the dentate gyrus
    Sharoni Jacobs
    Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 103:3902-7. 2006
  6. pmc Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats
    Sebastian Jessberger
    Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Learn Mem 16:147-54. 2009
  7. ncbi request reprint The adult substantia nigra contains progenitor cells with neurogenic potential
    D Chichung Lie
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Neurosci 22:6639-49. 2002
  8. pmc Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis
    Beate Winner
    Department of Neurology, University of Regensburg, Universitaetsstr 84, 93053 Regensburg, Germany
    Neurobiol Aging 29:913-25. 2008
  9. ncbi request reprint Human wild-type alpha-synuclein impairs neurogenesis
    Beate Winner
    Department of Neurology, University of Regensburg, Regensburg, Germany
    J Neuropathol Exp Neurol 63:1155-66. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Neurogenesis in the adult brain: new strategies for central nervous system diseases
    D Chichung Lie
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037, USA
    Annu Rev Pharmacol Toxicol 44:399-421. 2004
    ..Here, we summarize our current understanding of the mechanisms controlling adult neurogenesis and discuss their implications for the development of new strategies for the treatment of neurodegenerative diseases...
  2. ncbi request reprint New regulators in adult neurogenesis and their potential role for repair
    Ravi Jagasia
    Institute of Developmental Genetics, GSF National Research Center for Environment and Health, 85764 Munich Neuherberg, Germany
    Trends Mol Med 12:400-5. 2006
    ..Here, we discuss recent findings on the regulatory mechanisms that underlie neurogenesis from neural stem cells in the adult hippocampus and the implications of these findings for future stem-cell-based repair strategies...
  3. doi request reprint Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus
    Helena Mira
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Cell Stem Cell 7:78-89. 2010
    ..BMPs are therefore required to balance NSC quiescence/proliferation and to prevent loss of the stem cell activity that supports continuous neurogenesis in the mature hippocampus...
  4. pmc Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus
    Sebastian Jessberger
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California, USA
    PLoS Biol 6:e272. 2008
    ..The data presented here also suggest a mechanistic dissociation between accurate dendritic targeting and subsequent synapse formation...
  5. pmc Retinoic acid is required early during adult neurogenesis in the dentate gyrus
    Sharoni Jacobs
    Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 103:3902-7. 2006
    ..Our results reveal RA as a crucial contributor to early stages of adult neurogenesis and survival in vivo...
  6. pmc Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats
    Sebastian Jessberger
    Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Learn Mem 16:147-54. 2009
    ....
  7. ncbi request reprint The adult substantia nigra contains progenitor cells with neurogenic potential
    D Chichung Lie
    Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Neurosci 22:6639-49. 2002
    ..This developmental potential of SN progenitor cells might be useful for future endogenous cell replacement strategies in Parkinson's disease...
  8. pmc Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis
    Beate Winner
    Department of Neurology, University of Regensburg, Universitaetsstr 84, 93053 Regensburg, Germany
    Neurobiol Aging 29:913-25. 2008
    ..The impaired neurogenesis in the olfactory bulb of different transgenic alpha-synuclein mice during aging highlights the need to further explore the interplay between olfactory dysfunction and neurogenesis in Parkinson disease...
  9. ncbi request reprint Human wild-type alpha-synuclein impairs neurogenesis
    Beate Winner
    Department of Neurology, University of Regensburg, Regensburg, Germany
    J Neuropathol Exp Neurol 63:1155-66. 2004
    ..We hypothesize that reduced adult neurogenesis in the olfactory bulb may contribute to olfactory deficits in neurodegenerative disorders associated with alpha-synuclein inclusions...