Research Topics
| Chris A LiacourasSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
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Detail Information
Publications
Pharmacologic treatment of eosinophilic esophagitisChris A Liacouras
University of Pennsylvania School of Medicine, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
Gastrointest Endosc Clin N Am 18:169-78; xi. 2008..Providing the appropriate therapy depends on the significance of clinical symptoms, association of abnormal anatomy, and histologic involvement of underlying the esophageal tissue. This article focuses on the pharmacotherapy of EE...
Eosinophilic esophagitis: updated consensus recommendations for children and adultsChris A Liacouras
Center for Pediatric Eosinophilic Disorders, Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Allergy Clin Immunol 128:3-20.e6; quiz 21-2. 2011..Further advances and controversies regarding diagnostic methods, surrogate disease markers, allergy testing, and treatment approaches are discussed...
Eosinophilic esophagitisChris A Liacouras
Department of Anatomic Pathology, University of Pennsylvania School of Medicine, Pennsylvania 19104, USA
Curr Opin Pediatr 16:560-6. 2004..Because the incidence of EE is rising and EE is easily diagnosed by endoscopy with biopsy, it is important for physicians to not only accurately identify patients with EE but also understand the treatment options available...
Eosinophilic esophagitisChris A Liacouras
University of Pennsylvania School of Medicine, Center for Pediatric Eosinophilic Disorders, Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Gastroenterol Clin North Am 37:989-98, xi. 2008..Although the exact mechanism of EoE is unknown, food allergens are thought to have an important role. Effective treatment options include dietary restrictions and various steroid formulations...
Eosinophilic esophagitis: treatment in 2005Chris A Liacouras
University of Pennsylvania School of Medicine, Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Curr Opin Gastroenterol 22:147-52. 2006..Because the incidence is rising and the condition is easily diagnosed by endoscopy with biopsy, it is important for physicians to understand the pathophysiology, clinical presentation, and treatment options available for patients...
Eosinophilic esophagitis in children and adultsChris A Liacouras
Division of Gastroenterology and Nutrition, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Pediatr Gastroenterol Nutr 37:S23-8. 2003..Reports support the efficacy of dietary restriction or corticosteroid therapy. Additional research is needed to determine etiology, allow earlier clinical recognition, and improve treatment...
Eosinophilic esophagitis: a 10-year experience in 381 childrenChris A Liacouras
Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Clin Gastroenterol Hepatol 3:1198-206. 2005..We present information relating to our 10-year experience in children diagnosed with EoE...
14 years of eosinophilic esophagitis: clinical features and prognosisJonathan M Spergel
Division of Allergy and Immunology, The Children s Hospital of Philadelphia, USA
J Pediatr Gastroenterol Nutr 48:30-6. 2009..To determine the natural history of treated and untreated eosinophilic esophagitis (EE) and examine the presenting symptoms of EE...
Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch testsJonathan M Spergel
Division of Allergy and Immunology, The Children s Hospital of Philadelphia, Pennsylvania 19104 4399, USA
Ann Allergy Asthma Immunol 95:336-43. 2005..Therapies have included corticosteroids, elemental diet, and diet restriction. We report our experience with skin prick and atopy patch testing and food elimination diets in patients diagnosed as having EE...
Identification of causative foods in children with eosinophilic esophagitis treated with an elimination dietJonathan M Spergel
Division of Allergy and Immunology, Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
J Allergy Clin Immunol 130:461-7.e5. 2012..Eosinophilic esophagitis (EoE) is a chronic inflammatory disease with isolated eosinophils in the esophagus predominantly triggered by foods. The optimal testing to identify inciting foods remains unclear...
Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trialJonathan M Spergel
Division of Allergy and Immunology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 129:456-63, 463.e1-3. 2012..Eosinophilic esophagitis is a chronic allergic disease with insufficient treatment options. Results from animal studies suggest that IL-5 induces eosinophil trafficking in the esophagus...
Eosinophilic esophagitisJonathan E Markowitz
Division of Gastroenterology and Nutrition, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
Gastroenterol Clin North Am 32:949-66. 2003..These reviews coupled with the past reports and increasing incidence of EoE provide a sound background for further research on the etiology, epidemiology and treatment of EoE...
Eosinophilic esophagitisJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, 3333 Burnet Avenue, ML 2010, Cincinnati, OH 45229, USA
Immunol Allergy Clin North Am 29:19-27, viii. 2009..Referral to an allergist and food allergen testing is recommended. Dietary and topical corticosteroid therapies are commonly used and are effective in the majority of patients...
Changing indications for upper endoscopy in children during a 20-year periodJames P Franciosi
Cincinnati Children s Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati, OH 45229, USA
J Pediatr Gastroenterol Nutr 51:443-7. 2010..The aim of this study was to identify changes in subject characteristics and endoscopic procedures during a 20-year interval in children undergoing EGD at a single center...
Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatmentGlenn T Furuta
Section of Pediatric Gastroenterology, Hepatology, and Nutrition, The Children s Hospital, Denver, University of Colorado Medical School, Denver, Colorado, USA
Gastroenterology 133:1342-63. 2007..Since EE is a relatively new disease, the intent of this report is to provide current recommendations for care of affected patients and defining gaps in knowledge for future research studies...
The use of skin prick tests and patch tests to identify causative foods in eosinophilic esophagitisJonathan M Spergel
Allergy Section, Division of Immunologic and Infectious Disease, The Children's Hospital of Philadelphia, PA 19104, USA
J Allergy Clin Immunol 109:363-8. 2002..CONCLUSION: The combination of skin prick testing and patch testing can identify potential causative foods that might contribute to the pathogenesis of eosinophilic esophagitis...
Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescentsJonathan E Markowitz
Divisions of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Am J Gastroenterol 98:777-82. 2003..5 days. CONCLUSIONS: Elemental diet resulted in striking improvement in both symptoms and histologic evidence of disease in children and adolescents with EoE, as identified by strict diagnostic criteria...
Evaluation and management of foreign bodies in the upper gastrointestinal tractRuben W Cerri
The Children's Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, USA
Pediatr Case Rev 3:150-6. 2003
Eosinophilic esophagitisTerri Brown Whitehorn
Division of Allergy and Immunology, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
Curr Opin Pediatr 19:575-80. 2007..We present a review of the literature including basic science research, prevalence, clinical presentation, diagnosis, and management of eosinophilic esophagitis...
Safety of intravenous midazolam and fentanyl for pediatric GI endoscopy: prospective study of 1578 endoscopiesPetar Mamula
Division of GI and Nutrition, The Children s Hospital of Philadelphia, Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Gastrointest Endosc 65:203-10. 2007..Data on safety of intravenous sedation in pediatric GI endoscopy are sparse...
Interventional upper endoscopy: the pediatric perspectiveSteven Liu
Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Curr Gastroenterol Rep 8:450-7. 2006..Continuing research in pediatric endoscopy will allow pediatric gastroenterologists to perfect existing interventional endoscopic techniques and to learn to perform new ones...
A case-control study of sociodemographic and geographic characteristics of 335 children with eosinophilic esophagitisJames P Franciosi
Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Clin Gastroenterol Hepatol 7:415-9. 2009..The epidemiology of pediatric eosinophilic esophagitis (EE) is poorly characterized. In this study, we aimed to determine demographic, socioeconomic, and geographic characteristics of our cohort of EE children...
A descriptive study of complications of gastrostomy tubes in childrenElizabeth Goldberg
Division of Gastroenterology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA
J Pediatr Nurs 25:72-80. 2010..The purpose of this study was to determine the number and types of complications experienced by children with gastrostomy tubes...
Summary of the First International Gastrointestinal Eosinophil Research SymposiumChris A Liacouras
J Pediatr Gastroenterol Nutr 45:370-91. 2007
Predictors of early recurrence of benign esophageal strictures: what about eosinophilic esophagitis?Chris A Liacouras
Am J Gastroenterol 99:182-3; author reply 184. 2004
Authors' response to detection of causative foods by skin prick and atopy patch tests in patients with eosinophilic esophagitis: things are not what they seemJonathan M Spergel
Ann Allergy Asthma Immunol 96:376-8. 2006
New visions for food allergy: an iPAC summary and future trendsPhilippe A Eigenmann
Department of Pediatrics, University Hospital of Geneva, Geneva, Switzerland
Pediatr Allergy Immunol 19:26-39. 2008....
Predictive values for skin prick test and atopy patch test for eosinophilic esophagitisJonathan M Spergel
J Allergy Clin Immunol 119:509-11. 2007
Research agenda for pediatric gastroenterology, hepatology and nutrition: endoscopy. Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition FoundationJoseph F Fitzgerald
Children's Digestive Health and Nutrition Foundation, PO Box 6, Flourtown, PA 19031, USA
J Pediatr Gastroenterol Nutr 35:S254-7. 2002
Sedation and anesthesia in pediatric endoscopy: one size does not fit allSteven M Schwarz
J Pediatr Gastroenterol Nutr 44:295-7. 2007
