Ariel J Levine

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint GDF3 at the crossroads of TGF-beta signaling
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, Rockefeller University, New York, New York 10021, USA
    Cell Cycle 5:1069-73. 2006
  2. ncbi request reprint GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Development 133:209-16. 2006
  3. pmc GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY, USA
    Dev Biol 325:43-8. 2009
  4. pmc Proposal of a model of mammalian neural induction
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Dev Biol 308:247-56. 2007
  5. ncbi request reprint TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    Daylon James
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Development 132:1273-82. 2005

Detail Information

Publications5

  1. ncbi request reprint GDF3 at the crossroads of TGF-beta signaling
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, Rockefeller University, New York, New York 10021, USA
    Cell Cycle 5:1069-73. 2006
    ..These combined findings raise the intriguing possibility that GDF-3 acts as a bi-functional protein, to regulate the balance between the two modes of TGF-beta signaling...
  2. ncbi request reprint GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Development 133:209-16. 2006
    ....
  3. pmc GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY, USA
    Dev Biol 325:43-8. 2009
    ..We suggest that GDF3 is either a bi-functional TGF-beta ligand, or, more likely, that it is a BMP inhibitor that can artificially activate Nodal signaling under non-physiological conditions...
  4. pmc Proposal of a model of mammalian neural induction
    Ariel J Levine
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10021, USA
    Dev Biol 308:247-56. 2007
    ..This model is very similar to the default model of neural induction in the frog, thus bridging the evolutionary gap between amphibians and mammals...
  5. ncbi request reprint TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    Daylon James
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Development 132:1273-82. 2005
    ..These data reveal a crucial role for TGFbeta signaling in the earliest stages of cell fate determination and demonstrate an interconnection between TGFbeta and WNT signaling in these contexts...