ping la

Summary

Affiliation: Childrens Hospital of Philadelphia
Location: Philadelphia, US

Publications

  1. pmc Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism
    Ping La
    Division of Neonatology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 288:12901-9. 2013
  2. pmc Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells
    Guang Yang
    Division of Neonatology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Physiol Lung Cell Mol Physiol 301:L187-96. 2011
  3. pmc NO inhibits hyperoxia-induced NF-κB activation in neonatal pulmonary microvascular endothelial cells
    Clyde J Wright
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Res 68:484-9. 2010
  4. pmc Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition
    Ping La
    Division of Neonatology, Children s Hospital of Philadelphia, PA 19104, USA
    J Biol Chem 284:36302-11. 2009
  5. pmc Hyperoxia-induced NF-kappaB activation occurs via a maturationally sensitive atypical pathway
    Clyde J Wright
    Division of Neonatology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Physiol Lung Cell Mol Physiol 296:L296-306. 2009

Collaborators

  • Phyllis A Dennery
  • Clyde J Wright
  • Guang Yang
  • Qing S Lin
  • Jessica E Bordner
  • Amal P Fernando
  • Maurice D Hinson
  • Fadeke Agboke
  • Fengming Chen
  • Tiangang Zhuang

Detail Information

Publications5

  1. pmc Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism
    Ping La
    Division of Neonatology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 288:12901-9. 2013
    ..We conclude that the mTORC1 pathway serves to modulate iron metabolism and homeostasis, and we speculate that iron deprivation may be an adjunct in the treatment of cancers characterized by constitutive mTORC1 activation...
  2. pmc Silencing hyperoxia-induced C/EBPα in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells
    Guang Yang
    Division of Neonatology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Physiol Lung Cell Mol Physiol 301:L187-96. 2011
    ..These data suggest that C/EBPα is an important regulator of postnatal alveolar epithelial cell proliferation and differentiation during injury and repair...
  3. pmc NO inhibits hyperoxia-induced NF-κB activation in neonatal pulmonary microvascular endothelial cells
    Clyde J Wright
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Res 68:484-9. 2010
    ..This may help to explain the protective effects of NO on hyperoxic injury in the developing lung vasculature...
  4. pmc Zinc protoporphyrin regulates cyclin D1 expression independent of heme oxygenase inhibition
    Ping La
    Division of Neonatology, Children s Hospital of Philadelphia, PA 19104, USA
    J Biol Chem 284:36302-11. 2009
    ..These observations show HO independent effects of ZnPP on cyclin D1 expression and tumorigenesis...
  5. pmc Hyperoxia-induced NF-kappaB activation occurs via a maturationally sensitive atypical pathway
    Clyde J Wright
    Division of Neonatology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Physiol Lung Cell Mol Physiol 296:L296-306. 2009
    ..Activation of this pathway in fetal cells may prevent the normal pattern of fibroblast apoptosis necessary for normal lung development, resulting in aberrant lung morphology in vivo...