Edo Kussell

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Phenotypic diversity, population growth, and information in fluctuating environments
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021 6399, USA
    Science 309:2075-8. 2005
  2. ncbi request reprint The designability hypothesis and protein evolution
    Edo Kussell
    Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Protein Pept Lett 12:111-6. 2005
  3. ncbi request reprint Polymer-population mapping and localization in the space of phenotypes
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Avenue, Box 34, New York, New York 10021, USA
    Phys Rev Lett 97:068101. 2006
  4. pmc Individual histories and selection in heterogeneous populations
    Stanislas Leibler
    Center for Studies in Physics and Biology, and Laboratory of Living Matter, The Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 107:13183-8. 2010
  5. pmc Bacterial persistence: a model of survival in changing environments
    Edo Kussell
    Rockefeller University, New York, New York 10021 6399, USA
    Genetics 169:1807-14. 2005
  6. doi request reprint Evolution in microbes
    Edo Kussell
    Center for Genomics and Systems Biology, Department of Biology, Department of Physics, New York University, New York, New York 10003, USA
    Annu Rev Biophys 42:493-514. 2013
  7. pmc Stochastic de-repression of Rhodopsins in single photoreceptors of the fly retina
    Pranidhi Sood
    Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA
    PLoS Comput Biol 8:e1002357. 2012
  8. ncbi request reprint Side-chain dynamics and protein folding
    Edo Kussell
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Proteins 52:303-21. 2003
  9. ncbi request reprint Glassy dynamics of side-chain ordering in a simple model of protein folding
    Edo Kussell
    Department of Biophysics, Harvard University, 240 Longwood Avenue, Boston, Massachusetts 02115, USA
    Phys Rev Lett 89:168101. 2002
  10. pmc A structure-based method for derivation of all-atom potentials for protein folding
    Edo Kussell
    Department of Biophysics, Harvard University, 240 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:5343-8. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Phenotypic diversity, population growth, and information in fluctuating environments
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021 6399, USA
    Science 309:2075-8. 2005
    ..The optimal switching rates then mimic the statistics of environmental changes. We derive a relation between the long-term growth rate of the organism and the information available about its fluctuating environment...
  2. ncbi request reprint The designability hypothesis and protein evolution
    Edo Kussell
    Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Protein Pept Lett 12:111-6. 2005
    ..It is argued that designability is one component of fold fitness, but most likely not a dominant one...
  3. ncbi request reprint Polymer-population mapping and localization in the space of phenotypes
    Edo Kussell
    Laboratory of Living Matter and Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Avenue, Box 34, New York, New York 10021, USA
    Phys Rev Lett 97:068101. 2006
    ..Using this mapping, we develop a path integral formulation for populations and predict the existence of a biological counterpart for the well-known heteropolymer localization phase transition...
  4. pmc Individual histories and selection in heterogeneous populations
    Stanislas Leibler
    Center for Studies in Physics and Biology, and Laboratory of Living Matter, The Rockefeller University, 1230 York Avenue, Box 34, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 107:13183-8. 2010
    ....
  5. pmc Bacterial persistence: a model of survival in changing environments
    Edo Kussell
    Rockefeller University, New York, New York 10021 6399, USA
    Genetics 169:1807-14. 2005
    ..In contrast to typical examples of adaptations to features of a single environment, persistence appears to constitute an adaptation that is tuned to the distribution of environmental change...
  6. doi request reprint Evolution in microbes
    Edo Kussell
    Center for Genomics and Systems Biology, Department of Biology, Department of Physics, New York University, New York, New York 10003, USA
    Annu Rev Biophys 42:493-514. 2013
    ..Second, populations are viewed from a physiological perspective, and their nongenetic heterogeneity is examined. Bringing together these two viewpoints remains a major challenge for the future...
  7. pmc Stochastic de-repression of Rhodopsins in single photoreceptors of the fly retina
    Pranidhi Sood
    Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, USA
    PLoS Comput Biol 8:e1002357. 2012
    ..Our results indicate that even in the absence of Dve, the Rhodopsin regulatory network can maintain highly stable states. We propose that the role of Dve in outer PRs is to buffer against rare fluctuations in this network...
  8. ncbi request reprint Side-chain dynamics and protein folding
    Edo Kussell
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Proteins 52:303-21. 2003
    ..The postnucleation processes by which side chains relax are characterized by very slow dynamics and many barrier crossings, and thus resemble the behavior of a glass...
  9. ncbi request reprint Glassy dynamics of side-chain ordering in a simple model of protein folding
    Edo Kussell
    Department of Biophysics, Harvard University, 240 Longwood Avenue, Boston, Massachusetts 02115, USA
    Phys Rev Lett 89:168101. 2002
    ..We find that as temperature is lowered, side-chain ordering becomes much slower than backbone folding. The presence of side chains leads to nonexponential kinetics and a broad distribution of relaxation times...
  10. pmc A structure-based method for derivation of all-atom potentials for protein folding
    Edo Kussell
    Department of Biophysics, Harvard University, 240 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:5343-8. 2002
    ....