Deborah Kuban

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Long-term failure patterns and survival in a randomized dose-escalation trial for prostate cancer. Who dies of disease?
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 79:1310-7. 2011
  2. ncbi request reprint Hazards of dose escalation in prostate cancer radiotherapy
    Deborah Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:1260-8. 2003
  3. ncbi request reprint Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:915-28. 2003
  4. ncbi request reprint Failure definition-dependent differences in outcome following radiation for localized prostate cancer: can one size fit all?
    Deborah Kuban
    Department of Radiation Oncology, MD Anderson Cancer Center Orlando, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:409-14. 2005
  5. ncbi request reprint Radiation for prostate cancer: use of biochemical failure as an endpoint following radiotherapy
    Deborah A Kuban
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, TX 77030, Houston, USA
    World J Urol 21:253-64. 2003
  6. ncbi request reprint Ultrasound-based localization
    Deborah A Kuban
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Semin Radiat Oncol 15:180-91. 2005
  7. ncbi request reprint Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 70:67-74. 2008
  8. ncbi request reprint Comparison of biochemical failure definitions for permanent prostate brachytherapy
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 65:1487-93. 2006
  9. ncbi request reprint PSA after radiation for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77007, USA
    Oncology (Williston Park) 18:595-604; discussion 605, 609. 2004
  10. ncbi request reprint High-dose intensity modulated radiation therapy for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, Houston, TX 77007, USA
    Curr Urol Rep 5:197-202. 2004

Detail Information

Publications92

  1. doi request reprint Long-term failure patterns and survival in a randomized dose-escalation trial for prostate cancer. Who dies of disease?
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 79:1310-7. 2011
    ..To report long-term failure patterns and survival in a randomized radiotherapy dose escalation trial for prostate cancer...
  2. ncbi request reprint Hazards of dose escalation in prostate cancer radiotherapy
    Deborah Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 57:1260-8. 2003
    ..To assess the benefit of escalating the dose in definitive prostate cancer radiotherapy vs. the associated risk of complications...
  3. ncbi request reprint Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:915-28. 2003
    ..To report the long-term outcome for patients with Stage T1-T2 adenocarcinoma of the prostate definitively irradiated in the prostate-specific antigen (PSA) era...
  4. ncbi request reprint Failure definition-dependent differences in outcome following radiation for localized prostate cancer: can one size fit all?
    Deborah Kuban
    Department of Radiation Oncology, MD Anderson Cancer Center Orlando, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:409-14. 2005
    ..To compare long-term outcome using alternative failure definitions after external beam radiation for localized prostate cancer...
  5. ncbi request reprint Radiation for prostate cancer: use of biochemical failure as an endpoint following radiotherapy
    Deborah A Kuban
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, TX 77030, Houston, USA
    World J Urol 21:253-64. 2003
    ..A summary of these results and the associated issues are presented here...
  6. ncbi request reprint Ultrasound-based localization
    Deborah A Kuban
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Semin Radiat Oncol 15:180-91. 2005
    ..For breast cancer radiotherapy, ultrasound serves to define involved primary and nodal sites, especially in patients in whom surgical evaluation will not be the first therapeutic step...
  7. ncbi request reprint Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 70:67-74. 2008
    ..To report the long-term results of a randomized radiotherapy dose escalation trial for prostate cancer...
  8. ncbi request reprint Comparison of biochemical failure definitions for permanent prostate brachytherapy
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 65:1487-93. 2006
    ..To assess prostate-specific antigen (PSA) failure definitions for patients with Stage T1-T2 prostate cancer treated by permanent prostate brachytherapy...
  9. ncbi request reprint PSA after radiation for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77007, USA
    Oncology (Williston Park) 18:595-604; discussion 605, 609. 2004
    ..The concept of a universal definition of failure that might be applied to multiple modalities, including surgery, should also be investigated, at least for comparative study and research purposes...
  10. ncbi request reprint High-dose intensity modulated radiation therapy for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology, M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, Houston, TX 77007, USA
    Curr Urol Rep 5:197-202. 2004
    ..This technique continues to evolve, working toward image-guided radiation therapy, which is adjusted daily for positional and architectural changes of the gland...
  11. ncbi request reprint Improved biochemical relapse-free survival with increased external radiation doses in patients with localized prostate cancer: the combined experience of nine institutions in patients treated in 1994 and 1995
    Patrick Kupelian
    Department of Radiation Oncology, M D Anderson Cancer Center Orlando, Orlando, FL 32806, USA
    Int J Radiat Oncol Biol Phys 61:415-9. 2005
    ..To study the radiation dose-response as determined by Kaplan-Meier prostate-specific antigen (PSA) disease-free survival (PSA-DFS) estimates in patients with stage T1-T2 prostate cancer treated within a 2-year period (1994-1995)...
  12. doi request reprint The role of overall treatment time in the outcome of radiotherapy of prostate cancer: an analysis of biochemical failure in 4839 men treated between 1987 and 1995
    Howard D Thames
    Division of Quantitative Sciences, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Radiother Oncol 96:6-12. 2010
    ..Assess the importance of overall time (OT) and dose for biochemical failure (BF) after external-beam radiotherapy of prostate cancer in a retrospective analysis of a nine-institution database with 4839 patients...
  13. ncbi request reprint Comparison of alternative biochemical failure definitions based on clinical outcome in 4839 prostate cancer patients treated by external beam radiotherapy between 1986 and 1995
    Howard Thames
    Department of Biomathematics, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:929-43. 2003
    ....
  14. ncbi request reprint Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy
    Susan L Tucker
    Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 60:1589-601. 2004
    ..To compare the fits of normal-tissue complication probability (NTCP) models based on rectal dose-wall histograms (DWHs) vs. dose-volume histograms (DVHs) when the two are used to analyze a common set of late rectal toxicity data...
  15. pmc Investigation of bladder dose and volume factors influencing late urinary toxicity after external beam radiotherapy for prostate cancer
    M Rex Cheung
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 67:1059-65. 2007
    ..We sought to identify the bladder dose-volume factors associated with an increased risk of late urinary toxicity among prostate cancer patients treated with radiotherapy...
  16. ncbi request reprint Dose-volume response analyses of late rectal bleeding after radiotherapy for prostate cancer
    Susan L Tucker
    Department of Biostatistics and Applied Mathematics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:353-65. 2004
    ..To compare the fits of various normal tissue complication probability (NTCP) models to a common set of late rectal toxicity data, with the aim of identifying the best model for predicting late rectal injury after irradiation...
  17. ncbi request reprint Year of treatment as independent predictor of relapse-free survival in patients with localized prostate cancer treated with definitive radiotherapy in the PSA era
    Patrick Kupelian
    Department of Radiation Oncology, M D Anderson Cancer Center Orlando, Orlando, FL 32806, USA
    Int J Radiat Oncol Biol Phys 63:795-9. 2005
    ..Accounting for these changes would facilitate the retrospective comparison of outcomes for patients treated in different periods...
  18. ncbi request reprint An automatic CT-guided adaptive radiation therapy technique by online modification of multileaf collimator leaf positions for prostate cancer
    Laurence E Court
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:154-63. 2005
    ....
  19. ncbi request reprint Outcome of salvage radiotherapy for biochemical failure after radical prostatectomy with or without hormonal therapy
    Rex Cheung
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 63:134-40. 2005
    ..By comparing the outcomes for patients who received RT alone and for those who received combined RT and hormonal therapy, we assessed the potential benefits of hormonal therapy...
  20. doi request reprint Sunitinib plus androgen deprivation and radiation therapy for patients with localized high-risk prostate cancer: results from a multi-institutional phase 1 study
    Paul G Corn
    Department of Genitourinary Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 86:540-5. 2013
    ..To evaluate the feasibility of administering sunitinib in combination with androgen deprivation therapy and external-beam intensity modulated radiation therapy (XRT) in patients with localized high-risk prostate cancer...
  21. ncbi request reprint Predictive factors for late genitourinary and gastrointestinal toxicity in patients with prostate cancer treated with adjuvant or salvage radiotherapy
    Mary Feng
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 68:1417-23. 2007
    ..To determine the rate and magnitude of late genitourinary (GU) and gastrointestinal (GI) toxicities after salvage or adjuvant radiotherapy (RT) for prostate cancer, and to determine predictive factors for these toxicities...
  22. pmc Late rectal toxicity on RTOG 94-06: analysis using a mixture Lyman model
    Susan L Tucker
    Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1402, USA
    Int J Radiat Oncol Biol Phys 78:1253-60. 2010
    ....
  23. ncbi request reprint Cluster model analysis of late rectal bleeding after IMRT of prostate cancer: a case-control study
    Susan L Tucker
    Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 64:1255-64. 2006
    ..The purpose of this study was to test the validity of a two-dimensional cluster model of late rectal toxicity based on maximum cluster size of damage to rectal surface...
  24. ncbi request reprint Dose-response characteristics of low- and intermediate-risk prostate cancer treated with external beam radiotherapy
    Rex Cheung
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 97, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:993-1002. 2005
    ..We also investigated the differences in the dose-response characteristics using the American Society for Therapeutic Radiology and Oncology (ASTRO) definition vs. an alternative biochemical failure definition...
  25. ncbi request reprint Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for interfractional anatomic changes
    Radhe Mohan
    Department of Radiation Physics, Unit 94, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:1258-66. 2005
    ..In this paper, we report the development of one such intermediate method that takes into account anatomic changes by deforming the intensity distributions of each beam based on deformations of anatomy as seen in the beam's-eye-view...
  26. ncbi request reprint Prostate-specific antigen doubling time predicts clinical outcome and survival in prostate cancer patients treated with combined radiation and hormone therapy
    Andrew K Lee
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 63:456-62. 2005
    ..To determine whether prostate-specific antigen (PSA) doubling time predicts clinical outcomes in patients with prostate cancer that has been treated with combined radiation and hormone therapy...
  27. ncbi request reprint Comparison of treatment volumes and techniques in prostate cancer radiation therapy
    Catherine T Lee
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Oncol 28:618-25. 2005
    ....
  28. ncbi request reprint Dosimetric comparison of four target alignment methods for prostate cancer radiotherapy
    Jennifer C O'Daniel
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 66:883-91. 2006
    ..The aim of this study was to compare the dosimetric consequences of 4 treatment delivery techniques for prostate cancer patients treated with intensity-modulated radiotherapy (IMRT)...
  29. ncbi request reprint Characterization of rectal normal tissue complication probability after high-dose external beam radiotherapy for prostate cancer
    Rex Cheung
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 58:1513-9. 2004
    ..This study analyzed the utility and limitations of the widely used Lyman-Kutcher- Burman (LKB) normal tissue complication probability model in projecting the hazards of rectal complication with high-dose RT...
  30. ncbi request reprint PSA nadir predicts biochemical and distant failures after external beam radiotherapy for prostate cancer: a multi-institutional analysis
    Michael E Ray
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 64:1140-50. 2006
    ....
  31. ncbi request reprint Increased risk of biochemical and local failure in patients with distended rectum on the planning CT for prostate cancer radiotherapy
    Renaud de Crevoisier
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:965-73. 2005
    ....
  32. ncbi request reprint Hazard rates of disease progression after external beam radiotherapy for clinically localized carcinoma of the prostate
    Charles J Rosser
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Urol 169:2160-5. 2003
    ..We determined the likelihood of biochemical failure in those free of disease 5 years after radiotherapy and identified those at risk for early versus late biochemical failure...
  33. ncbi request reprint Prostate biopsy status and PSA nadir level as early surrogates for treatment failure: analysis of a prostate cancer randomized radiation dose escalation trial
    Alan Pollack
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 54:677-85. 2002
    ..These issues were investigated in a cohort of men with Stage T1-T3 prostate cancer who were randomized to receive between 70 Gy and 78 Gy and were prospectively biopsied at about 2 years after the completion of radiotherapy (RT)...
  34. ncbi request reprint Biochemical disease-free survival in men younger than 60 years with prostate cancer treated with external beam radiation
    Charles J Rosser
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Urol 168:536-41. 2002
    ..We also evaluated prognostic factors in the 2 age groups...
  35. ncbi request reprint Dose-response for biochemical control among high-risk prostate cancer patients after external beam radiotherapy
    Rex Cheung
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Boulevard, Box 97, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 56:1234-40. 2003
    ..In this study, we estimated the dose-response of prostate-specific antigen (PSA) control probability in high-risk prostate cancer patients treated with radiotherapy alone...
  36. ncbi request reprint Evaluation of a contour-alignment technique for CT-guided prostate radiotherapy: an intra- and interobserver study
    Laurence E Court
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 59:412-8. 2004
    ..The purpose of this study was to evaluate a manual alignment technique, in which the gross target volume contours are overlaid on the daily CT images and then shifted to match the structures visible in the images...
  37. doi request reprint Daily bone alignment with limited repeat CT correction rivals daily ultrasound alignment for prostate radiotherapy
    Jennifer C O'Daniel
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:274-80. 2008
    ....
  38. ncbi request reprint Late rectal toxicity: dose-volume effects of conformal radiotherapy for prostate cancer
    Eugene H Huang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 54:1314-21. 2002
    ..To identify dosimetric, anatomic, and clinical factors that correlate with late rectal toxicity after three-dimensional conformal radiotherapy (3D-CRT) for prostate cancer...
  39. ncbi request reprint Out-of-field photon and neutron dose equivalents from step-and-shoot intensity-modulated radiation therapy
    Stephen F Kry
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:1204-16. 2005
    ..intensity-modulated radiation therapy [IMRT]) at different treatment energies and delivered by different accelerators...
  40. ncbi request reprint Experience of ultrasound-based daily prostate localization
    Anurag Chandra
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:436-47. 2003
    ....
  41. ncbi request reprint Use of portal images and BAT ultrasonography to measure setup error and organ motion for prostate IMRT: implications for treatment margins
    Darren J Little
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:1218-24. 2003
    ..The aim of this study was to use both modalities to measure daily setup error and prostate organ motion and their respective contributions to the overall uncertainty of prostate target localization...
  42. ncbi request reprint Stage T1c prostate cancer: a heterogeneous category with widely varying prognosis
    Arthur Y Hung
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer J 8:440-4. 2002
    ....
  43. ncbi request reprint Defining recurrence after radiation for prostate cancer
    Deborah A Kuban
    Department of Radiation Oncology and Biostatistics, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    J Urol 173:1871-8. 2005
    ..We reviewed prostate specific antigen (PSA) definitions of recurrence after external beam radiation for prostatic cancer and related them to the definitions used for other treatment modalities...
  44. ncbi request reprint Changes in the pelvic anatomy after an IMRT treatment fraction of prostate cancer
    Renaud de Crevoisier
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:1529-36. 2007
    ..To quantify the three-dimensional variations of pelvic anatomy after a single treatment fraction...
  45. ncbi request reprint Utility of the percentage of positive prostate biopsies in predicting PSA outcome after radiotherapy for patients with clinically localized prostate cancer
    Ugur Selek
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:963-7. 2003
    ..To determine the utility of the percentage of positive prostate biopsies (PPPB) in predicting prostate-specific antigen (PSA) outcome after external beam radiotherapy alone...
  46. ncbi request reprint Multi-institutional analysis of long-term outcome for stages T1-T2 prostate cancer treated with permanent seed implantation
    Michael J Zelefsky
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 67:327-33. 2007
    ..To assess long-term prostate-specific antigen (PSA) outcome after permanent prostate brachytherapy (BT) and identify predictors of improved disease-free survival...
  47. ncbi request reprint Erectile dysfunction and radiation dose to penile base structures: a lack of correlation
    Ugur Selek
    Department of Radiation Oncology, Unit 97, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:1039-46. 2004
    ..To evaluate the relationship between the dose and volume of radiation to proximal penile structures and the development of erectile dysfunction after external beam radiotherapy (RT) for localized prostate adenocarcinoma...
  48. ncbi request reprint Identification of factors predicting response to adjuvant radiation therapy in patients with positive margins after radical prostatectomy
    Ashish M Kamat
    Department of Urology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Urol 170:1860-3. 2003
    ..Postoperative radiation therapy (RT) is often advocated for improving these outcomes. We identified predictors of response to adjuvant RT given for positive margins after RP...
  49. ncbi request reprint Influence of obesity on biochemical and clinical failure after external-beam radiotherapy for localized prostate cancer
    Sara S Strom
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:631-9. 2006
    ..The current study sought to determine whether obesity was an independent predictor of biochemical failure (BF) and clinical recurrence (CF) among patients treated with external-beam radiotherapy (EBRT)...
  50. ncbi request reprint Prostate specific antigen bounce phenomenon after external beam radiation for clinically localized prostate cancer
    Charles J Rosser
    Department of Urology, The University of Texas, M D Anderson Cancer Center, Houston 77030, USA
    J Urol 168:2001-5. 2002
    ..We characterize the prostate-specific antigen (PSA) bounce in patients who underwent external beam radiation therapy for prostate cancer and correlate the PSA bounce with the development of biochemical disease progression...
  51. ncbi request reprint Biochemical and clinical significance of the posttreatment prostate-specific antigen bounce for prostate cancer patients treated with external beam radiation therapy alone: a multiinstitutional pooled analysis
    Eric M Horwitz
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
    Cancer 107:1496-502. 2006
    ....
  52. ncbi request reprint Nadir prostate-specific antigen within 12 months after radiotherapy predicts biochemical and distant failure
    Michael E Ray
    Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0010, USA
    Urology 68:1257-62. 2006
    ..To determine whether nadir prostate-specific antigen (PSA) levels within 12 months (nadir PSA12) after completion of radiotherapy (RT) can be used as an early marker of recurrence risk...
  53. ncbi request reprint The predictive value of 2-year posttreatment biopsy after prostate cancer radiotherapy for eventual biochemical outcome
    Waseet Vance
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:828-33. 2007
    ..To determine the value of a 2-year post-radiotherapy (RT) prostate biopsy for predicting eventual biochemical failure in patients who were treated for localized prostate cancer...
  54. ncbi request reprint Quality-of-life questionnaire results 2 and 3 years after radiotherapy for prostate cancer in a randomized dose-escalation study
    Darren J Little
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Urology 62:707-13. 2003
    ..To assess patient-reported prostate cancer-specific quality of life 2 and 3 years after radiotherapy to the prostate in a randomized dose-escalation trial of 70 versus 78 Gy conducted from 1993 to 1998...
  55. ncbi request reprint Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States
    Steven J Frank
    Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Brachytherapy 6:2-8. 2007
    ..This study is aimed at understanding and defining the current patterns of care with respect to prostate brachytherapy for patients with intermediate-risk localized disease in the combined academic and community setting...
  56. doi request reprint Is a loose-seed nomogram still valid for prostate brachytherapy in a stranded-seed era?
    Rajat J Kudchadker
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 72:623-7. 2008
    ..To characterize the amount of activity required to treat the prostate with stranded (125)I radioactive seeds and compare our stranded data with the amount of activity recommended when individual seeds are implanted using a Mick applicator...
  57. ncbi request reprint Uncertainty of calculated risk estimates for secondary malignancies after radiotherapy
    Stephen F Kry
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 68:1265-71. 2007
    ..This work examines the uncertainty in absolute risk estimates and in the ratio of risk estimates between different treatment modalities...
  58. doi request reprint Recommendations for post-prostatectomy radiation therapy in the United States before and after the presentation of randomized trials
    Karen E Hoffman
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Urol 185:116-20. 2011
    ....
  59. ncbi request reprint Treatment-planning study of prostate cancer intensity-modulated radiotherapy with a Varian Clinac operated without a flattening filter
    Oleg N Vassiliev
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 68:1567-71. 2007
    ....
  60. pmc Effect of anatomic motion on proton therapy dose distributions in prostate cancer treatment
    Xiaodong Zhang
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:620-9. 2007
    ..To determine the dosimetric impact of interfraction anatomic movements in prostate cancer patients receiving proton therapy...
  61. doi request reprint Prostogram predicted brachytherapy outcomes are not universally accurate: an analysis based on the M. D. Anderson Cancer Center experience with (125)iodine brachytherapy
    Steven J Frank
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    J Urol 181:1658-63; discussion 1663-4. 2009
    ..We examined whether the Prostogram accurately predicted recurrence at 5 years in patients treated with (125)I brachytherapy at 1 tertiary cancer center...
  62. doi request reprint A volumetric trend analysis of the prostate and seminal vesicles during a course of intensity-modulated radiation therapy
    Steven J Frank
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Oncol 33:173-5. 2010
    ....
  63. ncbi request reprint An assessment of quality of life following radical prostatectomy, high dose external beam radiation therapy and brachytherapy iodine implantation as monotherapies for localized prostate cancer
    Steven J Frank
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Urol 177:2151-6; discussion 2156. 2007
    ..Monotherapy with radical prostatectomy, high dose external beam radiotherapy or a (125)I implant is reported to produce equivalent outcomes. We assessed the health related quality of life associated with these 3 treatment approaches...
  64. doi request reprint Quantification of prostate and seminal vesicle interfraction variation during IMRT
    Steven J Frank
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:813-20. 2008
    ....
  65. ncbi request reprint First-year PSA kinetics and minima after prostate cancer radiotherapy are predictive of overall survival
    Rex Cheung
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 66:20-4. 2006
    ..We analyzed whether first-year prostate-specific antigen (PSA) kinetics and minima are predictive of overall survival (OS)...
  66. ncbi request reprint Assessing the impact of an alternative biochemical failure definition on radiation dose response for high-risk prostate cancer treated with external beam radiotherapy
    Rex Cheung
    Departments of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:14-9. 2005
    ..We assessed the effect of using an alternative failure definition on the dose-response characteristics of high-risk prostate cancer treated with radiotherapy alone...
  67. ncbi request reprint Dosimetric consequences of using a surrogate urethra to estimate urethral dose after brachytherapy for prostate cancer
    Hoon K Lee
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:355-61. 2003
    ..To assess the accuracy and dosimetric consequences of defining a surrogate urethra at the geometric center of the prostate in postimplant CT scans...
  68. ncbi request reprint Bcl-2 is significantly overexpressed in localized radio-recurrent prostate carcinoma, compared with localized radio-naive prostate carcinoma
    Charles J Rosser
    Department of Urology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 56:1-6. 2003
    ....
  69. ncbi request reprint Symptomatic local recurrence of prostate carcinoma after radiation therapy
    Dan Leibovici
    Department of Urology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:2060-6. 2005
    ..Most reports on the results of RT for localized prostate carcinoma (PC) do not address this endpoint. The objective of this study was to determine the incidence of SLRPC and to identify the risk factors for this endpoint...
  70. doi request reprint Ductal adenocarcinoma of the prostate: clinical features and implications after local therapy
    Shi Ming Tu
    Department of Genitourinary Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:2872-80. 2009
    ..The authors of this report investigated the clinical outcome of patients who had prostate ductal adenocarcinoma after primary radical prostatectomy or radiotherapy...
  71. ncbi request reprint The calculated risk of fatal secondary malignancies from intensity-modulated radiation therapy
    Stephen F Kry
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:1195-203. 2005
    ..Step-and-shoot intensity-modulated radiation therapy (IMRT), an increasingly popular treatment modality, yields higher out-of-field doses than do conventional treatments, because of an increase in required monitor units (beam-on time)...
  72. ncbi request reprint Prostate cancer radiation dose response: results of the M. D. Anderson phase III randomized trial
    Alan Pollack
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 53:1097-105. 2002
    ..A randomized radiotherapy dose escalation trial was undertaken between 1993 and 1998 to compare the efficacy of 70 vs. 78 Gy in controlling prostate cancer...
  73. ncbi request reprint Increasing external beam dose for T1-T2 prostate cancer: effect on risk groups
    Howard D Thames
    Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, and Department of Radiation Oncology, William Beaumont Hospital, Deroit, MI, USA
    Int J Radiat Oncol Biol Phys 65:975-81. 2006
    ....
  74. ncbi request reprint Impact of androgen deprivation therapy on survival in men treated with radiation for prostate cancer
    Alan Pollack
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Urology 60:22-30; discussion 30-1. 2002
    ..The results with long-term ADT are much more convincing than short-term ADT, and, as a consequence, 2 to 3 years are recommended...
  75. ncbi request reprint Clinical features and treatment outcome of Hispanic men with prostate cancer following external beam radiotherapy
    Charles J Rosser
    Department of Urology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Urol 170:1856-9. 2003
    ..We retrospectively analyzed the clinical characteristics and outcomes of Hispanic men compared with other groups who underwent radiotherapy alone for localized or locally advanced prostate cancer...
  76. ncbi request reprint Intrafraction prostate motion during IMRT for prostate cancer
    Eugene Huang
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 53:261-8. 2002
    ..In this report, the B-mode, Acquisition, and Targeting (BAT) ultrasound system was used to measure intrafraction prostate motion during 200 intensity-modulated radiotherapy (IMRT) sessions for prostate cancer...
  77. pmc Performance evaluation of automatic anatomy segmentation algorithm on repeat or four-dimensional computed tomography images using deformable image registration method
    He Wang
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 72:210-9. 2008
    ..The goal of this study was to quantitatively evaluate the performance of the algorithm in typical clinical applications...
  78. ncbi request reprint The delivery of IMRT with a single physical modulator for multiple fields: a feasibility study for paranasal sinus cancer
    Jennifer C O'Daniel
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 58:876-87. 2004
    ..This technique reduces the treatment time and manufacturing costs typically associated with modulator-IMRT. Technical feasibility was evaluated for treating paranasal sinus cancers...
  79. ncbi request reprint Dose-volume conundrum for response of prostate cancer to brachytherapy: summary dosimetric measures and their relationship to tumor control probability
    WARREN D D'SOUZA
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Int J Radiat Oncol Biol Phys 58:1540-8. 2004
    ..g., moderate underdosing of large volumes vs. extreme underdosing of small volumes)...
  80. ncbi request reprint Validation of an accelerated 'demons' algorithm for deformable image registration in radiation therapy
    He Wang
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Phys Med Biol 50:2887-905. 2005
    ..Together, these results suggest that the accelerated demons algorithm has significant potential for delineating and tracking doses in targets and critical structures during CT-guided radiotherapy...
  81. ncbi request reprint Definitions of biochemical failure that best predict clinical failure in patients with prostate cancer treated with external beam radiation alone: a multi-institutional pooled analysis
    Eric M Horwitz
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111 2497, USA
    J Urol 173:797-802. 2005
    ..In this report we determined the sensitivity and specificity of several BF definitions using distant failure (DF) alone or clinical failure (CF), defined as local failure (LF) and/or DF...
  82. ncbi request reprint Implementation and validation of a three-dimensional deformable registration algorithm for targeted prostate cancer radiotherapy
    He Wang
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 61:725-35. 2005
    ..Daily prostate deformation hinders accurate calculation of dose, especially to intraprostatic targets. We implemented a three-dimensional deformable registration algorithm to aid dose tracking for targeted prostate radiotherapy...
  83. pmc Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer?
    Adam D Melancon
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, USA
    Radiother Oncol 85:251-9. 2007
    ....
  84. pmc Toward a real-time in vivo dosimetry system using plastic scintillation detectors
    Louis Archambault
    Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 78:280-7. 2010
    ..In the present study, we have presented and validated a plastic scintillation detector (PSD) system designed for real-time multiprobe in vivo measurements...
  85. pmc Racial influence on biochemical disease-free survival in men treated with external-beam radiotherapy for localized prostate cancer
    Charles J Rosser
    Department of Urology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Natl Med Assoc 96:939-44. 2004
    ..We retrospectively analyzed the clinical characteristics and outcomes of various racial and ethnic groups who underwent radiotherapy alone for localized or locally advanced prostate cancer...
  86. pmc Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer
    Colin Brooks
    Department of Experimental Radiation Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, TX, USA
    Radiat Oncol 7:154. 2012
    ..We have investigated the radiosensitizing effects of sunitinib, a potent, multi-tyrosine kinase inhibitor of the VEGFR and PDGFR receptors, on human prostate cancer cells...
  87. doi request reprint A multidisciplinary prostate cancer clinic for newly diagnosed patients: developing the role of the advanced practice nurse
    Lydia T Madsen
    Department of Genitourinary Medical Oncology, University of Texas, M D Anderson Cancer Center, Houston, TX, USA
    Clin J Oncol Nurs 13:305-9. 2009
    ..Formal evaluation of the MPCC showed that patients were satisfied with this approach to the complex decision-making process in prostate cancer...
  88. doi request reprint Surgical management of prostate cancer metastatic to the spine
    Brian J Williams
    Department of Neurosurgery, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Neurosurg Spine 10:414-22. 2009
    ..In this study, a series of patients undergoing spinal surgery for metastatic prostate cancer were reviewed to identify predictors of survival and functional outcome...
  89. doi request reprint Urinary side effects and complications after permanent prostate brachytherapy: the MD Anderson Cancer Center experience
    John F Anderson
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Urology 74:601-5. 2009
    ..To minimize the risk of long-term urinary morbidity, it is important for clinicians to be able to distinguish acute urinary side effects after prostate brachytherapy from longer-term treatment-related urinary complications...
  90. ncbi request reprint Is patient age a factor in the occurrence of prostate-specific antigen bounce phenomenon after external beam radiotherapy for prostate cancer?
    Charles J Rosser
    Department of Urology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Urology 66:327-31. 2005
    ..To evaluate the effect of patient age on the occurrence of prostate-specific antigen (PSA) "bounce" after external beam radiotherapy (EBRT) for prostate cancer...
  91. pmc Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy
    Andrew J Stephenson
    Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195 0001, USA
    J Clin Oncol 25:2035-41. 2007
    ..We developed a nomogram to predict the probability of cancer control at 6 years after SRT for PSA-defined recurrence...
  92. ncbi request reprint Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation
    Charles J Rosser
    Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Gene Ther 11:273-9. 2004
    ..These findings suggest that overexpression of Bcl-2 result in radioresistance and inability of radiation to cause its typical G2M cell-cycle arrest...