S Krishnamurthy

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
    Bisrat G Debeb
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Mol Cancer 9:180. 2010
  2. ncbi Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer
    Mustafa Akkiprik
    Department of Medical Biology, Marmara University, School of Medicine, 34668 Istanbul, Turkey
    Breast Cancer Res 10:212. 2008
  3. ncbi Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, Texas, USA
    BMC Cancer 6:68. 2006
  4. ncbi Characterization of foam cells in nipple aspirate fluid
    S Krishnamurthy
    Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Diagn Cytopathol 27:261-4; discussion 265. 2002
  5. ncbi Fine-needle aspiration cytology of mucinous tumors of the pancreas
    Monica Recine
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 102:92-9. 2004
  6. ncbi Applications of molecular techniques to fine-needle aspiration biopsy
    Savitri Krishnamurthy
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 111:106-22. 2007
  7. ncbi Nipple aspirate fluid cytology in breast carcinoma
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 99:97-104. 2003
  8. ncbi Current applications and future prospects of fine-needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:451-62. 2009
  9. ncbi A prospective study comparing touch imprint cytology, frozen section analysis, and rapid cytokeratin immunostain for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:1555-62. 2009
  10. ncbi Role of ultrasound-guided fine-needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma
    Savitri Krishnamurthy
    Department of Pathology, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:982-8. 2002

Detail Information

Publications77

  1. ncbi Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
    Bisrat G Debeb
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Mol Cancer 9:180. 2010
    ..Herein we fully characterize cancer stem cell-like features in 293T human embryonic kidney cells...
  2. ncbi Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer
    Mustafa Akkiprik
    Department of Medical Biology, Marmara University, School of Medicine, 34668 Istanbul, Turkey
    Breast Cancer Res 10:212. 2008
    ..An in-depth understanding of IGFBP-5 would shed light on its potential role as a target for breast cancer therapeutics...
  3. ncbi Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, Texas, USA
    BMC Cancer 6:68. 2006
    ....
  4. ncbi Characterization of foam cells in nipple aspirate fluid
    S Krishnamurthy
    Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Diagn Cytopathol 27:261-4; discussion 265. 2002
    ..There was no evidence, however, of cell junctions or tonofilaments. The immunocytochemical and electron microscopic findings of our study together clearly support a macrophage derivation for foam cells in nipple aspirate fluid...
  5. ncbi Fine-needle aspiration cytology of mucinous tumors of the pancreas
    Monica Recine
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 102:92-9. 2004
    ..The current study was designed to identify distinctive cytomorphologic features that would be useful for the categorization of mucinous tumors of the pancreas...
  6. ncbi Applications of molecular techniques to fine-needle aspiration biopsy
    Savitri Krishnamurthy
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 111:106-22. 2007
    ..Whereas few of these tests alone are used for patient care, some of them have the potential for clinical use in the near future...
  7. ncbi Nipple aspirate fluid cytology in breast carcinoma
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 99:97-104. 2003
    ..Cytologic-histologic correlations of NAF were performed in only a few studies...
  8. ncbi Current applications and future prospects of fine-needle aspiration biopsy of locoregional lymph nodes in the management of breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 117:451-62. 2009
    ..The feasibility of noninvasive imaging modalities for SLN mapping in animal models has indicated a good potential for FNA biopsy in the subsequent investigation of SLNs identified noninvasively in humans...
  9. ncbi A prospective study comparing touch imprint cytology, frozen section analysis, and rapid cytokeratin immunostain for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:1555-62. 2009
    ....
  10. ncbi Role of ultrasound-guided fine-needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma
    Savitri Krishnamurthy
    Department of Pathology, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:982-8. 2002
    ..This study was undertaken to determine the diagnostic accuracy of US-guided FNA of indeterminate/suspicious/metastatic-appearing axillary lymph nodes during the initial staging of breast carcinoma...
  11. ncbi Feasibility of breast-conserving surgery for patients with breast carcinoma associated with nipple discharge
    Neslihan Cabioglu
    Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:508-17. 2004
    ..Nonetheless, BCS can be performed safely if negative margins are achieved and if appropriate adjuvant radiotherapy or systemic therapy is administered...
  12. ncbi High and differential expression of HER-2/neu extracellular domain in bilateral ductal fluids from women with unilateral invasive breast cancer
    Henry M Kuerer
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 9:601-5. 2003
    ..Breast ductal fluid can be obtained from women by simple nipple aspiration and may be useful for analyzing the microenvironment of the breast...
  13. ncbi Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 10:248-54. 2003
    ..A scoring system incorporating these factors may help determine which patients would benefit from additional axillary surgery...
  14. ncbi Intraoperative touch imprint of sentinel lymph nodes in breast carcinoma patients
    Andrea Lee
    Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 96:225-31. 2002
    ..The difficulty of identifying micrometastases appeared to be the major source of false negative events, a problem that is not unique to TI cytology...
  15. ncbi Inflammatory breast cancer: the disease, the biology, the treatment
    Fredika M Robertson
    Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    CA Cancer J Clin 60:351-75. 2010
    ..This review examines IBC's unique clinical presentation, pathology, epidemiology, imaging, and biology and details current multidisciplinary management of the disease, which comprises systemic therapy, surgery, and radiation therapy...
  16. ncbi Identification of biomarkers for breast cancer in nipple aspiration and ductal lavage fluid
    Jinong Li
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Clin Cancer Res 11:8312-20. 2005
    ..To establish a comprehensive proteomic approach for biomarker discovery and validation in breast fluid...
  17. ncbi Is intraoperative touch imprint cytology of sentinel lymph nodes in patients with breast cancer cost effective?
    Jacqueline S Jeruss
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:2328-36. 2006
    ..The authors hypothesized that TIC, when compared with standard postoperative SLN assessment alone, would permit a cost-effective evaluation of SLNs in patients with clinically node-negative breast cancer...
  18. ncbi Accuracy and sensitivity of computed tomography-guided percutaneous needle biopsy of pulmonary hilar lymph nodes
    Rony Avritscher
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 116:1974-80. 2010
    ..The purpose of this study was to retrospectively evaluate the sensitivity and accuracy of CT-guided PNB in patients with hilar adenopathy...
  19. ncbi Association between ductal fluid proteomic expression profiles and the presence of lymph node metastases in women with breast cancer
    Henry M Kuerer
    Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    Surgery 136:1061-9. 2004
    ..High-throughput proteomic methods may reveal biologically relevant proteins involved in carcinogenesis and progression of disease...
  20. ncbi Classifying local disease recurrences after breast conservation therapy based on location and histology: new primary tumors have more favorable outcomes than true local disease recurrences
    Eugene Huang
    Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:2059-67. 2002
    ..This is because patients with new carcinomas had significantly lower rates of metastasis than those with local disease recurrence, but were more likely to develop contralateral breast carcinomas...
  21. ncbi Role of primary tumor characteristics in predicting positive sentinel lymph nodes in patients with ductal carcinoma in situ or microinvasive breast cancer
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg 196:81-7. 2008
    ..We determined the incidence of positive sentinel lymph nodes (SLNs) in patients with ductal carcinoma in situ (DCIS) or microinvasive breast cancer (MIC) and the predictive factors of SLN metastasis in these patients...
  22. ncbi Impact of clinicopathological factors on sensitivity of axillary ultrasonography in the detection of axillary nodal metastases in patients with breast cancer
    Isabelle Bedrosian
    Departments of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 10:1025-30. 2003
    ..No significant clinicopathologic criteria were found to impact sensitivity of ultrasonography; however, excisional biopsy for diagnosis may be a confounding variable in subsequent axillary ultrasonography...
  23. ncbi Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlations
    M Cristofanilli
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Oncol 19:1713-9. 2008
    ..We tested the activity of imatinib mesylate in MBC with overexpression of PDGFR or c-kit. Additionally, we sought to determine the biological correlates and immunomodulatory effects...
  24. ncbi A nonreplicating adenoviral vector that contains the wild-type p53 transgene combined with chemotherapy for primary breast cancer: safety, efficacy, and biologic activity of a novel gene-therapy approach
    Massimo Cristofanilli
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
    Cancer 107:935-44. 2006
    ....
  25. ncbi Small (</=2-cm) subpleural pulmonary lesions: short- versus long-needle-path CT-guided Biopsy--comparison of diagnostic yields and complications
    Sanjay Gupta
    Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 325, Houston, TX 77030, USA
    Radiology 234:631-7. 2005
    ..To retrospectively compare the diagnostic yield and complications associated with the use of short versus long needle paths for computed tomography (CT)-guided biopsy of small subpleural lung lesions...
  26. ncbi Significant differences in nipple aspirate fluid protein expression between healthy women and those with breast cancer demonstrated by time-of-flight mass spectrometry
    Timothy M Pawlik
    Department of Surgical Oncology, Unit 444, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res Treat 89:149-57. 2005
    ..Proteomic screening techniques such as SELDI-MS analysis of NAF may be useful for breast cancer screening and diagnosis...
  27. ncbi Thyroid hormone and breast carcinoma. Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma
    Massimo Cristofanilli
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:1122-8. 2005
    ....
  28. ncbi Squamous cell carcinoma of the breast
    Bryan T Hennessy
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Clin Oncol 23:7827-35. 2005
    ..D. Anderson Cancer Center (Houston, TX) and a series of 137 patients identified through the Surveillance, Epidemiology, and End Results (SEER) database to make therapy recommendations...
  29. ncbi Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    Bryan T Hennessy
    Department of Gynecologic Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Res 69:4116-24. 2009
    ..PIK3CA mutations, EMT, and stem cell-like characteristics likely contribute to the poor outcomes of MBC and suggest novel therapeutic targets...
  30. ncbi Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow
    Anthony Lucci
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Breast Cancer Res Treat 117:61-8. 2009
    ....
  31. ncbi A phase I study to assess the feasibility and oncologic safety of axillary reverse mapping in breast cancer patients
    Isabelle Bedrosian
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston Texas, USA
    Cancer 116:2543-8. 2010
    ..This study reported a phase 1 trial conducted in patients with cytologically documented axillary metastasis undergoing axillary lymph node dissection to determine the feasibility and oncologic safety of ARM...
  32. ncbi Ductal carcinoma in situ: state of the science and roadmap to advance the field
    Henry M Kuerer
    The University of Texas M D Anderson Cancer Center, DCIS Discovery Program and Department of Surgical Oncology, 1515 Holcombe Blvd, Unit 444, Houston, TX 77030, USA
    J Clin Oncol 27:279-88. 2009
    ..Understanding of the biology and clinical behavior of DCIS is imperfect. This article highlights the current knowledge base and the scientific roadmap needed to advance the field...
  33. ncbi CT-guided percutaneous lung biopsies in patients with haematologic malignancies and undiagnosed pulmonary lesions
    Sanjay Gupta
    Department of Diagnostic Radiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Hematol Oncol 28:75-81. 2010
    ....
  34. ncbi Prospective evaluation of a novel approach for the use of a quantitative galactose oxidase-Schiff reaction in ductal fluid samples from women with breast carcinoma
    Anees Chagpar
    Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:2549-54. 2004
    ..The preliminary results support further exploration of this novel quantitative test in patients with breast carcinoma...
  35. ncbi Histologic localization of sentinel lymph node metastases in breast cancer
    Leslie K Diaz
    Department of Pathology, M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 27:385-9. 2003
    ..This information may be useful in determining the optimal method for evaluating axillary sentinel lymph node specimens from breast cancer patients...
  36. ncbi Total RNA yield and microarray gene expression profiles from fine-needle aspiration biopsy and core-needle biopsy samples of breast carcinoma
    W Fraser Symmans
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 97:2960-71. 2003
    ..This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy (CBX)...
  37. ncbi Positive surgical margins and ipsilateral breast tumor recurrence predict disease-specific survival after breast-conserving therapy
    Funda Meric
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 97:926-33. 2003
    ....
  38. ncbi CT-guided percutaneous fine-needle aspiration biopsy of small (< or =1-cm) pulmonary lesions
    Michael J Wallace
    Departments of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 325, Houston, TX 77030 4009, USA
    Radiology 225:823-8. 2002
    ..To determine the accuracy of percutaneous computed tomography (CT)-guided fine-needle aspiration biopsy (FNAB) of small (< or =1.0-cm in diameter) pulmonary lesions...
  39. ncbi Clinical, histopathologic, and biologic features of pleomorphic lobular (ductal-lobular) carcinoma in situ of the breast: a report of 24 cases
    Nour Sneige
    Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mod Pathol 15:1044-50. 2002
    ..Long-term follow-up studies are needed to further define the natural history of PL/DLCIS and its optimal management...
  40. ncbi Immunocytochemical evaluation of estrogen receptor on archival Papanicolaou-stained fine-needle aspirate smears
    Savitri Krishnamurthy
    Department of Pathology, MD Anderson Cancer Center, The University of Texas, Houston, Texas 77030, USA
    Diagn Cytopathol 29:309-14. 2003
    ..Because significant differences in ER-IC staining can occur with any of the immunocytochemical methods, a negative result is less reliable as an indicator of true ER status than a positive result...
  41. ncbi Feasibility and utility of using chromosomal aneusomy to further define the cytologic categories in nipple aspirate fluid specimens: a preliminary study
    Savitri Krishnamurthy
    Department of Cytopathology, Unit 53, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer 102:322-7. 2004
    ....
  42. ncbi Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinoma
    Yun Gong
    Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 102:34-40. 2004
    ..Air-drying, destaining Pap smear, and fixation in formalin or Carnoy's-Pap without antigen retrieval are not recommended...
  43. ncbi Fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma
    S Krishnamurthy
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Diagn Cytopathol 22:299-303. 2000
    ..The patient underwent left radical nephrectomy as well as a combined cardiopulmonary bypass, with atriotomy and resection of the tumor from the right atrium and inferior vena cava. Three months of postoperative follow-up were uneventful...
  44. ncbi Lack of association between amplification of her-2 and response to preoperative taxanes in patients with breast carcinoma
    Ana M Gonzalez-Angulo
    Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:258-63. 2004
    ..45 and P = 0.14, respectively). CONCLUSIONS: her-2 gene amplification was not found to be predictive of a pathologic response to preoperative taxanes in patients with early-stage breast carcinoma...
  45. ncbi Molecular and biologic markers of premalignant lesions of human breast
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA
    Adv Anat Pathol 9:185-97. 2002
    ....
  46. ncbi Identification of distinct protein expression patterns in bilateral matched pair breast ductal fluid specimens from women with unilateral invasive breast carcinoma. High-throughput biomarker discovery
    Henry M Kuerer
    Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 95:2276-82. 2002
    ..Recent advances in image analysis, automated mass spectrometry, and bioinformatics have provided the tools necessary to use ductal fluids from breast carcinoma patients for high-throughput biomarker discovery...
  47. ncbi Ultrasound-guided fine needle aspiration cytodiagnosis of leiomyosarcoma metastatic to the breast. A case report
    Merle N Madigan
    Departments of Pathology and Radiology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 53, Houston, Texas 77030, USA
    Acta Cytol 47:783-6. 2003
    ....
  48. ncbi Cortical morphologic features of axillary lymph nodes as a predictor of metastasis in breast cancer: in vitro sonographic study
    Deepak G Bedi
    Division of Diagnostic Imaging, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1350, Houston, TX 77030, USA
    AJR Am J Roentgenol 191:646-52. 2008
    ....
  49. ncbi Validation of a breast cancer nomogram for predicting nonsentinel lymph node metastases after a positive sentinel node biopsy
    Laura A Lambert
    Department of Surgical Oncology, Unit 444, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Ann Surg Oncol 13:310-20. 2006
    ..TIC seems to be an acceptable substitute for frozen section as a nomogram variable. The nomogram may help predict an individual's risk of non-SLN metastases and assist in patient decision making regarding the benefit of CLND...
  50. ncbi Ultrasound-guided fine-needle aspiration biopsy of the thyroid bed
    S Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 93:199-205. 2001
    ..The purposes of this study were to determine the sensitivity and specificity of US-guided FNAB of the thyroid bed for diagnosing recurrent carcinoma after total thyroidectomy and to highlight potential diagnostic pitfalls...
  51. ncbi Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer
    Balraj Singh
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Clin Exp Metastasis 27:233-40. 2010
    ..05). However, CTCE-9908 as a single therapy inhibited organ-specific metastasis to leg (P < 0.05 by chi-squared test and by two-sample t-test)...
  52. ncbi Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer
    Dongwei Zhang
    Breast Cancer Translational Research Laboratory, Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 15:6639-48. 2009
    ..Epidermal growth factor receptor (EGFR) expression is an independent poor prognostic factor in IBC. The purpose of this study was to determine the effect on IBC tumorigenicity and metastasis of blocking the EGFR pathway...
  53. ncbi Percutaneous image-guided splenic biopsy in the oncology patient: an audit of 156 consecutive cases
    Alda Tam
    Division of Diagnostic Imaging, Interventional Radiology Section, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Vasc Interv Radiol 19:80-7. 2008
    ..To assess the safety and diagnostic accuracy of percutaneous image-guided splenic biopsy in patients known to have or suspected of having malignancy...
  54. ncbi Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGen AdnaTest BreastCancer Select/Detect™ versus Veridex CellSearch™ system
    E Andreopoulou
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 130:1590-7. 2012
    ..While there is concordance between these 2 methods, the AdnaTest complements the CellSearch system by improving the overall CTC detection rate and permitting the assessment of genomic markers in CTCs...
  55. ncbi Collagen IV levels are elevated in the serum of patients with primary breast cancer compared to healthy volunteers
    C Mazouni
    Laboratoire de transfert biologique et oncologique, Marseille University, Houston, TX, USA
    Br J Cancer 99:68-71. 2008
    ..In conclusion, patients with breast cancer have elevated levels of collagen IV compared to healthy women and collagen IV levels increase further during chemotherapy...
  56. ncbi Fine needle aspiration cytology of a skeletal metastasis of adult Wilms' tumor. A case report
    F Lin
    Department of Pathology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Acta Cytol 45:393-8. 2001
    ....
  57. ncbi Detection of minimal residual disease in blood and bone marrow in early stage breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:3330-7. 2010
    ..In this study, the authors investigated the occurrence of CTCs and DTCs in women with early stage breast cancer and evaluated the correlation of their presence with other prognostic markers...
  58. ncbi Comparison of immunomarkers for the identification of adrenocortical cells in cytology specimens
    Mehri Jalali
    Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, 77030, USA
    Diagn Cytopathol 33:78-82. 2005
    ....
  59. ncbi Fine-needle aspiration of an unusual case of poorly differentiated insular carcinoma of the thyroid
    Yun Gong
    Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
    Diagn Cytopathol 32:103-7. 2005
    ..The limitations of FNA in the sampling of a large tumor with heterogeneous patterns should be kept in mind when interpreting the cytomorphological and immunocytochemical results...
  60. ncbi PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase
    Chandra Bartholomeusz
    Breast Cancer Translational Research Laboratory, Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 16:1802-11. 2010
    ..To determine the role of PEA-15 in breast cancer...
  61. ncbi Fine-needle aspiration cytology of a case of HIV-associated anaplastic myeloma
    John M M Stewart
    Department of Pathology, MD Anderson Cancer Center, University of Texas, Houston, Texas 77030-4095, USA
    Diagn Cytopathol 27:218-22. 2002
    ..His HIV load increased, and his malignancy rapidly progressed with the development of multiple vertebral lesions, extraosseous extension, and eventually cord compression. He died of the disease less than 2 mo after presentation...
  62. ncbi Pulmonary epithelioid hemangioendothelioma with prominent signet ring cell features mimicking metastatic adenocarcinoma
    Elena N Hristova
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030-4009, USA
    Ann Diagn Pathol 7:160-4. 2003
    ..This case clearly indicates the importance of recognizing the cytomorphologic and histologic spectrum of this entity to avoid misdiagnosing it as either primary or metastatic adenocarcinoma...
  63. ncbi HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer
    Julie E Lang
    Department of Surgical Oncology, MD Anderson Cancer Center, Advanced Research Center for Microscopic Disease, The University of Texas, Houston, TX 77030, USA
    Breast Cancer Res Treat 113:501-7. 2009
    ..We hypothesized that primary tumor characteristics would predict the likelihood of identifying CTCs in patients with operable breast cancer...
  64. ncbi Atypical ductal hyperplasia diagnosis by directional vacuum-assisted stereotactic biopsy of breast microcalcifications. Considerations for surgical excision
    Nour Sneige
    Department of Pathology, University of Texas M.D. Anderson Cancer Center, Unit 53, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Clin Pathol 119:248-53. 2003
    ..When assessing microcalcifications with ADH, clinicians should consider the percentage of microcalcifications removed by DVAB and the extent of lobular involvement to better assess the need for excision...
  65. ncbi Immunocytochemical study of the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma
    Amy C Baruch
    Department of Cytopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Diagn Cytopathol 35:143-7. 2007
    ..The presence of occasional mesothelin expression in benign tissue, its very focal expression in malignant tissue may limit the utility of mesothelin as a marker of pancreatic adenocarcinomas in fine-needle aspiration (FNA) specimens...
  66. ncbi Dielectric cell separation of fine needle aspirates from tumor xenografts
    Massimo Cristofanilli
    Department of Breast Medical Oncology, University of Texas, Houston, TX, USA
    J Sep Sci 31:3732-9. 2008
    ..The approach has the potential to facilitate the analysis of the role of cell subpopulations in disease...
  67. ncbi Acquired resistance to erlotinib in A-431 epidermoid cancer cells requires down-regulation of MMAC1/PTEN and up-regulation of phosphorylated Akt
    Fumiyuki Yamasaki
    Breast Cancer Translational Research Laboratory, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer Res 67:5779-88. 2007
    ..We propose that acquired erlotinib resistance associated with MMAC1/PTEN down-regulation and Akt activation could be overcome by inhibitors of signaling through the phosphatidylinositol 3-kinase pathway...
  68. ncbi Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits
    C H Yang
    Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Oncol 17:813-7. 2006
    ..The future development of this agent for the treatment of breast cancer should be guided by in vivo models that optimize activity in combination with other antitumor agents...
  69. ncbi Mammary angiosarcomas: imaging findings in 24 patients
    Wei Tse Yang
    Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Radiology 242:725-34. 2007
    ..To retrospectively evaluate the clinical, imaging, and pathologic findings of mammary angiosarcomas in 24 patients...
  70. ncbi Hepatic artery chemoembolization for 110 gastrointestinal stromal tumors: response, survival, and prognostic factors
    Katsuhiro Kobayashi
    Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA
    Cancer 107:2833-41. 2006
    ..Extent of liver disease, presence of extrahepatic disease, number of embolization treatments, and use of imatinib were found to have prognostic influence on PFS, OS, or both...
  71. ncbi The many faces of fat necrosis in the breast
    Jorge L Taboada
    Department of Diagnostic Radiology, Unit 1350, PO Box 301439, M D Anderson Cancer Center, Houston, TX 77230 1439, USA
    AJR Am J Roentgenol 192:815-25. 2009
    ..Mammography is more specific than sonography, and emphasis should be placed on mammography in making the diagnosis of fat necrosis. In selected cases, MRI may be helpful in showing findings consistent with fat necrosis...
  72. ncbi Important technical considerations for skin-sparing mastectomy with sentinel lymph node dissection
    Henry Mark Kuerer
    Arch Surg 137:747. 2002
  73. ncbi Breast cancer in the asian Indian population of the United States: a call for screening and education
    Roshni Rao
    Breast J 14:402-3. 2008
  74. ncbi MUC4 interacts with ErbB2 in human gallbladder carcinoma: potential pathobiological implications
    Naoki Miyahara
    Department of Gastroenterology, Institute of Clinical Medicine, University of Tsukuba Graduate School of Comprehensive Human Sciences, 1 1 1 Tennodai, Tsukuba shi, Ibaraki 305 8575, Japan
    Eur J Cancer 44:1048-56. 2008
    ..These findings suggest that MUC4 is up-regulated and interacts with erbB2 in human gallbladder carcinoma, and thereby support the potential implication of MUC4 in erbB2 activation...
  75. ncbi Intramammary lymph node metastases are an independent predictor of poor outcome in patients with breast carcinoma
    Jeannie Shen
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Cancer 101:1330-7. 2004
    ..Identification of malignant intraMLNs by lymphatic mapping may help to identify high-risk patients for whom further evaluation of the axillary lymph nodes is warranted despite otherwise clinically negative findings in the axilla...
  76. ncbi Radiation-induced atypical glandular cells mimicking recurrent adenocarcinoma in a posthysterectomy vaginal smear
    Z Laura Tabatabai
    Acta Cytol 47:106-7. 2003
  77. ncbi An unusual solid pseudopapillary tumor of the pancreas
    Maria C Uzquiano
    Pancreas 33:103-4. 2006