Neeltje A Kootstra

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Gene therapy with viral vectors
    Neeltje A Kootstra
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037 1099, USA
    Annu Rev Pharmacol Toxicol 43:413-39. 2003
  2. ncbi request reprint Efficient production of human FVIII in hemophilic mice using lentiviral vectors
    Neeltje A Kootstra
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037, USA
    Mol Ther 7:623-31. 2003
  3. pmc Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
    Neeltje A Kootstra
    Laboratory of Genetics and Infectious Disease Laboratory, The Salk Institute, La Jolla, CA 92037 1099, USA
    Proc Natl Acad Sci U S A 100:1298-303. 2003
  4. ncbi request reprint Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes
    Tippi C MacKenzie
    Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Mol Ther 6:349-58. 2002
  5. ncbi request reprint Efficient transduction of simian cells by HIV-1-based lentiviral vectors that contain mutations in the capsid protein
    Maarten A N Rits
    Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, Amsterdam, The Netherlands
    Mol Ther 15:930-7. 2007

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Gene therapy with viral vectors
    Neeltje A Kootstra
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037 1099, USA
    Annu Rev Pharmacol Toxicol 43:413-39. 2003
    ..Even though the results of these trials are encouraging, vector development is still required to improve and refine future treatment of hereditary disorders...
  2. ncbi request reprint Efficient production of human FVIII in hemophilic mice using lentiviral vectors
    Neeltje A Kootstra
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037, USA
    Mol Ther 7:623-31. 2003
    ..The challenge is to overcome the immune barriers to the therapeutic gene product...
  3. pmc Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
    Neeltje A Kootstra
    Laboratory of Genetics and Infectious Disease Laboratory, The Salk Institute, La Jolla, CA 92037 1099, USA
    Proc Natl Acad Sci U S A 100:1298-303. 2003
    ..Overall, the findings demonstrate that the host range of HIV-1-based LV can be altered by modifications in the packaging construct...
  4. ncbi request reprint Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes
    Tippi C MacKenzie
    Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Mol Ther 6:349-58. 2002
    ..m. and i.h. injection of all three vectors. Our findings of long-term transduction of skeletal myocytes and cardiomyocytes after in utero administration suggest a novel strategy for the treatment of congenital muscular dystrophies...
  5. ncbi request reprint Efficient transduction of simian cells by HIV-1-based lentiviral vectors that contain mutations in the capsid protein
    Maarten A N Rits
    Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, Amsterdam, The Netherlands
    Mol Ther 15:930-7. 2007
    ..Therefore, this LV might be very useful for long-term safety studies in large animal models like rhesus macaques...