Robert J Klein

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc RSEARCH: finding homologs of single structured RNA sequences
    Robert J Klein
    Howard Hughes Medical Institute and Department of Genetics, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    BMC Bioinformatics 4:44. 2003
  2. pmc Noncoding RNA genes identified in AT-rich hyperthermophiles
    Robert J Klein
    Howard Hughes Medical Institute and Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 99:7542-7. 2002
  3. pmc Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA
    Am J Hum Genet 77:149-53. 2005
  4. pmc Power analysis for genome-wide association studies
    Robert J Klein
    Program in Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
    BMC Genet 8:58. 2007

Collaborators

Detail Information

Publications4

  1. pmc RSEARCH: finding homologs of single structured RNA sequences
    Robert J Klein
    Howard Hughes Medical Institute and Department of Genetics, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    BMC Bioinformatics 4:44. 2003
    ..No programs have yet been published that allow searching a sequence database for homologs of a single RNA molecule on the basis of secondary structure...
  2. pmc Noncoding RNA genes identified in AT-rich hyperthermophiles
    Robert J Klein
    Howard Hughes Medical Institute and Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 99:7542-7. 2002
    ..furiosus. Nine of the 30 new candidate genes predicted by these screens have been verified to produce discrete, apparently noncoding transcripts with sizes ranging from 97 to 277 nucleotides...
  3. pmc Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA
    Am J Hum Genet 77:149-53. 2005
    ..39 (95% confidence interval 0.36-0.42) and the genotype relative risk to be 2.44 (95% confidence interval 2.08-2.83) for TC heterozygotes and 5.93 (95% confidence interval 4.33-8.02) for CC homozygotes...
  4. pmc Power analysis for genome-wide association studies
    Robert J Klein
    Program in Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
    BMC Genet 8:58. 2007
    ..To choose the proper sample size and genotyping platform for such studies, power calculations that take into account genetic model, tag SNP selection, and the population of interest are required...