Megan C King

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors
    Stephen K Dove
    School of Biosciences, University of Birmingham, Birmingham, UK
    EMBO J 23:1922-33. 2004
  2. ncbi Karyopherin-mediated import of integral inner nuclear membrane proteins
    Megan C King
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 442:1003-7. 2006
  3. pmc A network of nuclear envelope membrane proteins linking centromeres to microtubules
    Megan C King
    Laboratory of Cell Biology, The Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 134:427-38. 2008
  4. ncbi Highway to the inner nuclear membrane: rules for the road
    C Patrick Lusk
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Nat Rev Mol Cell Biol 8:414-20. 2007
  5. pmc Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB
    Megan C King
    Department of Biochemistry and Biophysics and the Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 101:8957-62. 2004
  6. ncbi The single transmembrane domains of ErbB receptors self-associate in cell membranes
    Jeannine M Mendrola
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 277:4704-12. 2002

Collaborators

  • Gunter Blobel
  • Mark Lemmon
  • Robert C Piper
  • C Patrick Lusk
  • Stephen K Dove
  • Jeannine M Mendrola
  • David C Hughes
  • Peter J Parker
  • Robert H Michell
  • Jong W Yu
  • Andrew B Holmes
  • Jan Thuring
  • Robert K McEwen
  • Frank T Cooke
  • Mitchell B Berger

Detail Information

Publications6

  1. pmc Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors
    Stephen K Dove
    School of Biosciences, University of Birmingham, Birmingham, UK
    EMBO J 23:1922-33. 2004
    ..Svp1p is not involved in the contributions of FAB1/PtdIns(3,5)P2 to MVB sorting or to vacuole acidification and so additional PtdIns(3,5)P2 effectors must exist...
  2. ncbi Karyopherin-mediated import of integral inner nuclear membrane proteins
    Megan C King
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 442:1003-7. 2006
    ..We also provide evidence that specific nuclear pore complex proteins contribute to this process, suggesting a role for signal-mediated alterations in the nuclear pore complex to allow for passage of INM proteins along the pore membrane...
  3. pmc A network of nuclear envelope membrane proteins linking centromeres to microtubules
    Megan C King
    Laboratory of Cell Biology, The Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 134:427-38. 2008
    ..This work highlights a framework for communication between cytoplasmic microtubules and chromatin...
  4. ncbi Highway to the inner nuclear membrane: rules for the road
    C Patrick Lusk
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Nat Rev Mol Cell Biol 8:414-20. 2007
    ..Here we develop a set of rules that might govern the transport of proteins to the inner nuclear membrane...
  5. pmc Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB
    Megan C King
    Department of Biochemistry and Biophysics and the Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 101:8957-62. 2004
    ..These studies indicate an unexpected role for a dynamin-like protein in nucleocytoplasmic trafficking and suggest that a related function might be usurped by its antiviral relatives...
  6. ncbi The single transmembrane domains of ErbB receptors self-associate in cell membranes
    Jeannine M Mendrola
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 277:4704-12. 2002
    ..Our findings suggest a role for TM domain interactions in ErbB receptor function, possibly in stabilizing inactive ligand-independent receptor dimers that have been observed by several groups...