Megan C King

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors
    Stephen K Dove
    School of Biosciences, University of Birmingham, Birmingham, UK
    EMBO J 23:1922-33. 2004
  2. ncbi Karyopherin-mediated import of integral inner nuclear membrane proteins
    Megan C King
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 442:1003-7. 2006
  3. pmc A network of nuclear envelope membrane proteins linking centromeres to microtubules
    Megan C King
    Laboratory of Cell Biology, The Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 134:427-38. 2008
  4. ncbi Highway to the inner nuclear membrane: rules for the road
    C Patrick Lusk
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Nat Rev Mol Cell Biol 8:414-20. 2007
  5. pmc Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB
    Megan C King
    Department of Biochemistry and Biophysics and the Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 101:8957-62. 2004
  6. ncbi The single transmembrane domains of ErbB receptors self-associate in cell membranes
    Jeannine M Mendrola
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 277:4704-12. 2002

Research Grants

Collaborators

Detail Information

Publications6

  1. pmc Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors
    Stephen K Dove
    School of Biosciences, University of Birmingham, Birmingham, UK
    EMBO J 23:1922-33. 2004
    ..Svp1p is not involved in the contributions of FAB1/PtdIns(3,5)P2 to MVB sorting or to vacuole acidification and so additional PtdIns(3,5)P2 effectors must exist...
  2. ncbi Karyopherin-mediated import of integral inner nuclear membrane proteins
    Megan C King
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Nature 442:1003-7. 2006
    ..We also provide evidence that specific nuclear pore complex proteins contribute to this process, suggesting a role for signal-mediated alterations in the nuclear pore complex to allow for passage of INM proteins along the pore membrane...
  3. pmc A network of nuclear envelope membrane proteins linking centromeres to microtubules
    Megan C King
    Laboratory of Cell Biology, The Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 134:427-38. 2008
    ..This work highlights a framework for communication between cytoplasmic microtubules and chromatin...
  4. ncbi Highway to the inner nuclear membrane: rules for the road
    C Patrick Lusk
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Nat Rev Mol Cell Biol 8:414-20. 2007
    ..Here we develop a set of rules that might govern the transport of proteins to the inner nuclear membrane...
  5. pmc Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB
    Megan C King
    Department of Biochemistry and Biophysics and the Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 101:8957-62. 2004
    ..These studies indicate an unexpected role for a dynamin-like protein in nucleocytoplasmic trafficking and suggest that a related function might be usurped by its antiviral relatives...
  6. ncbi The single transmembrane domains of ErbB receptors self-associate in cell membranes
    Jeannine M Mendrola
    Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6059, USA
    J Biol Chem 277:4704-12. 2002
    ..Our findings suggest a role for TM domain interactions in ErbB receptor function, possibly in stabilizing inactive ligand-independent receptor dimers that have been observed by several groups...

Research Grants1

  1. Nuclear envelope membrane proteins and nuclear structure
    Megan King; Fiscal Year: 2007
    ..This proposal focuses on the role of NE membrane proteins in maintaining the structural integrity provided by the NE, with a particular focus on the role of the transmembrane (TM) and lumenal domains of NE membrane proteins. ..