Janice K Kiecolt-Glaser

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Spousal support satisfaction as a modifier of physiological responses to marital conflict in younger and older couples
    Kathi L Heffner
    Department of Psychiatry, College of Medicine, Ohio State University, 200 Porter Hall, Athens, Ohio 45701, USA
    J Behav Med 27:233-54. 2004
  2. pmc Close relationships, inflammation, and health
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Neurosci Biobehav Rev 35:33-8. 2010
  3. ncbi request reprint Psychoneuroimmunology and cancer: fact or fiction?
    J K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210, USA
    Eur J Cancer 35:1603-7. 1999
  4. pmc Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychosom Med 69:217-24. 2007
  5. pmc How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis
    Janice K Kiecolt-Glaser
    The Ohio State University College of Medicine, Department of Psychiatry, 1670 Upham Drive, Columbus, OH 43210, United States
    Psychoneuroendocrinology 34:670-80. 2009
  6. ncbi request reprint Hostile marital interactions, proinflammatory cytokine production, and wound healing
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Arch Gen Psychiatry 62:1377-84. 2005
  7. pmc Olfactory influences on mood and autonomic, endocrine, and immune function
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychoneuroendocrinology 33:328-39. 2008
  8. ncbi request reprint Love, marriage, and divorce: newlyweds' stress hormones foreshadow relationship changes
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine and Ohio State Institute for Behavioral Medicine Research, Columbus 43210, USA
    J Consult Clin Psychol 71:176-88. 2003
  9. ncbi request reprint Marriage and health: his and hers
    J K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, Ohio 43210, USA
    Psychol Bull 127:472-503. 2001
  10. ncbi request reprint Psychoneuroimmunology and psychosomatic medicine: back to the future
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
    Psychosom Med 64:15-28. 2002

Research Grants

  1. Psychoneuroimmunology and Mind-Body Medicine
    Janice Kiecolt Glaser; Fiscal Year: 2005
  2. Psychoneuroimmunology and Mind-Body Interventions
    Janice Kiecolt Glaser; Fiscal Year: 2006
  3. Aging, Stress, Fatty Acids and Inflammation
    Janice Kiecolt Glaser; Fiscal Year: 2007
  4. Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and Distress
    Janice Kiecolt Glaser; Fiscal Year: 2007
  5. Depression, Stress, Aging & Proinflammatory Cytokines
    Janice Kiecolt Glaser; Fiscal Year: 2007
  6. Stress and Proinflammatory Cytokines: Omega-3 Intervention
    Janice Kiecolt Glaser; Fiscal Year: 2007

Detail Information

Publications66

  1. ncbi request reprint Spousal support satisfaction as a modifier of physiological responses to marital conflict in younger and older couples
    Kathi L Heffner
    Department of Psychiatry, College of Medicine, Ohio State University, 200 Porter Hall, Athens, Ohio 45701, USA
    J Behav Med 27:233-54. 2004
    ..These relationships provide a window on mechanisms linking marriage and health for men and women across the life span...
  2. pmc Close relationships, inflammation, and health
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Neurosci Biobehav Rev 35:33-8. 2010
    ..Despite some notable methodological challenges, the evidence suggests that learning more about how close relationships influence inflammation will provide important new insights into the ways that relationships impact health...
  3. ncbi request reprint Psychoneuroimmunology and cancer: fact or fiction?
    J K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210, USA
    Eur J Cancer 35:1603-7. 1999
    ..These studies and others suggest that psychological or behavioural factors may influence the incidence or progression of cancer through psychosocial influences on immune function and other physiological pathways...
  4. pmc Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychosom Med 69:217-24. 2007
    ..Dietary intakes of omega-3 (n-3) and omega-6 (n-6) PUFAs also influence inflammation; high n-6:n-3 ratios enhance proinflammatory cytokine production, although n-3 has anti-inflammatory properties...
  5. pmc How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis
    Janice K Kiecolt-Glaser
    The Ohio State University College of Medicine, Department of Psychiatry, 1670 Upham Drive, Columbus, OH 43210, United States
    Psychoneuroendocrinology 34:670-80. 2009
    ..Greater anxiety was associated with more IL-6 production by Con A-stimulated leukocytes following the stressor compared to the control visit. The data suggest that stress and anxiety can enhance and prolong AR symptoms...
  6. ncbi request reprint Hostile marital interactions, proinflammatory cytokine production, and wound healing
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Arch Gen Psychiatry 62:1377-84. 2005
    ..In addition, depression and stress are associated with enhanced production of proinflammatory cytokines that influence a spectrum of conditions associated with aging...
  7. pmc Olfactory influences on mood and autonomic, endocrine, and immune function
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychoneuroendocrinology 33:328-39. 2008
    ..Odors did not reliably alter IL-6 and IL-10 production, salivary cortisol, heart rate or blood pressure, skin barrier repair following tape stripping, or pain ratings following the cold pressor...
  8. ncbi request reprint Love, marriage, and divorce: newlyweds' stress hormones foreshadow relationship changes
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine and Ohio State Institute for Behavioral Medicine Research, Columbus 43210, USA
    J Consult Clin Psychol 71:176-88. 2003
    ..Couples whose marriages were troubled at follow-up produced 34% more norepinephrine during conflict, 24% more norepinephrine during the daytime, and 17% more during nighttime hours at Time 1 than the untroubled...
  9. ncbi request reprint Marriage and health: his and hers
    J K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, Ohio 43210, USA
    Psychol Bull 127:472-503. 2001
    ..Contemporary models of gender that emphasize self-processes, traits, and roles furnish alternative perspectives on the differential costs and benefits of marriage for men's and women's health...
  10. ncbi request reprint Psychoneuroimmunology and psychosomatic medicine: back to the future
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
    Psychosom Med 64:15-28. 2002
    ..This article speculates on future directions for psychoneuroimmunology research, after reviewing the history of the field...
  11. ncbi request reprint Psychoneuroimmunology: psychological influences on immune function and health
    Janice K Kiecolt-Glaser
    Department of Psychiatry and Institute for Behavioral Medicine Research, Ohio State University College of Medicine, Columbus 43210, USA
    J Consult Clin Psychol 70:537-47. 2002
    ....
  12. ncbi request reprint Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology
    Janice K Kiecolt-Glaser
    Department of Psychiatry The Ohio State University College of Medicine, 1670 Upham Drive, Columbus, Ohio 43210, USA
    Annu Rev Psychol 53:83-107. 2002
    ..Resources such as close personal relationships that diminish negative emotions enhance health in part through their positive impact on immune and endocrine regulation...
  13. ncbi request reprint Hypnosis as a modulator of cellular immune dysregulation during acute stress
    J K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210, USA
    J Consult Clin Psychol 69:674-82. 2001
    ..These data provide encouraging evidence that interventions may reduce the immunological dysregulation associated with acute stressors...
  14. pmc Fatigue and herpesvirus latency in women newly diagnosed with breast cancer
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 26:394-400. 2012
    ..Prior work has suggested that fatigue may be related to inflammation and its associated sickness behaviors; accordingly, our findings may be tapping into this same physiological substrate...
  15. pmc Long lasting effects of smoking: breast cancer survivors' inflammatory responses to acute stress differ by smoking history
    Jeanette M Bennett
    Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Psychoneuroendocrinology 38:179-87. 2013
    ..An exaggerated and prolonged inflammatory response to stress could be one mechanism underlying the persistent inflammation observed in former smokers...
  16. pmc Inflammation and reactivation of latent herpesviruses in older adults
    Jeanette M Bennett
    Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 26:739-46. 2012
    ..Thus, reactivation of multiple herpesviruses may drive inflammation and could contribute to poorer health among older adults...
  17. pmc Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, OH 43210, USA
    Brain Behav Immun 25:1725-34. 2011
    ..ClinicalTrials.gov identifier: NCT00519779...
  18. pmc Loneliness predicts pain, depression, and fatigue: understanding the role of immune dysregulation
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 614, United States
    Psychoneuroendocrinology 38:1310-7. 2013
    ..Latent herpesvirus reactivation, which is reflected by elevated herpesvirus antibody titers, provides a window into immune dysregulation. Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are two common herpesviruses...
  19. pmc Loneliness promotes inflammation during acute stress
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, 460 Medical Center Dr, Columbus, OH 43210, USA
    Psychol Sci 24:1089-97. 2013
    ..These data provide a glimpse into the pathways through which loneliness may affect health. ..
  20. pmc Poorer self-rated health is associated with elevated inflammatory markers among older adults
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Psychoneuroendocrinology 36:1495-504. 2011
    ....
  21. pmc Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 460 Medical Center Drive, Columbus, OH 43210, USA
    Psychosom Med 73:16-22. 2011
    ..Previous research on the physical health consequences of childhood abuse and other adversities has been based on data from young or middle-aged adults...
  22. pmc Immune dysregulation and chronic stress among older adults: a review
    Jean Philippe Gouin
    Department of Psychology, Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Neuroimmunomodulation 15:251-9. 2008
    ..The chronic stress-induced immune dysregulation observed among older caregivers appears to be of sufficient magnitude to impact health. Furthermore, evidence suggests that chronic stress leads to premature aging of the immune system...
  23. pmc Stress, inflammation, and yoga practice
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Psychosom Med 72:113-21. 2010
    ..Stressors before each of the three conditions provided data on the extent to which yoga speeded an individual's physiological recovery...
  24. pmc Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, OH 43210, USA
    Brain Behav Immun 26:988-95. 2012
    ..These data provide a window into the ways in which the n-3 PUFAs may impact disease initiation, progression, and resolution. ClinicalTrials.gov identifier: NCT00385723...
  25. pmc Basal cell carcinoma: stressful life events and the tumor environment
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Arch Gen Psychiatry 69:618-26. 2012
    ..Basal cell carcinoma (BCC) is the most common skin cancer, and the immune system plays a prominent role in tumor appearance and progression...
  26. ncbi request reprint Hostility and pain are related to inflammation in older adults
    Jennifer E Graham
    Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University College of Medicine, USA
    Brain Behav Immun 20:389-400. 2006
    ..Our results also shed light on inflammation as a mechanism underlying the effects of hostility on cardiovascular disease morbidity and mortality...
  27. pmc Chronic stress and age-related increases in the proinflammatory cytokine IL-6
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 100:9090-5. 2003
    ..These data provide evidence of a key mechanism through which chronic stressors may accelerate risk of a host of age-related diseases by prematurely aging the immune response...
  28. pmc Synergistic relationships among stress, depression, and troubled relationships: insights from psychoneuroimmunology
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Depress Anxiety 30:288-96. 2013
    ..Understanding the links among stress, depression, troubled relationships, and inflammation is an exciting area of research that may provide mechanistic insight into the links between distress and poor health...
  29. pmc Marital behavior, oxytocin, vasopressin, and wound healing
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, Columbus, OH 43210 1228, USA
    Psychoneuroendocrinology 35:1082-90. 2010
    ..These data confirm and extend prior evidence implicating oxytocin and vasopressin in couples' positive and negative communication behaviors, and also provide further evidence of their role in an important health outcome, wound healing...
  30. ncbi request reprint Mild depressive symptoms are associated with amplified and prolonged inflammatory responses after influenza virus vaccination in older adults
    Ronald Glaser
    Departments of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, Columbus, OH 43210, USA
    Arch Gen Psychiatry 60:1009-14. 2003
    ..In this prospective community study, we assessed the relationship between depressive symptoms and changes in inflammatory response after an influenza virus vaccination...
  31. pmc Attachment anxiety is linked to alterations in cortisol production and cellular immunity
    Lisa M Jaremka
    The Ohio State University College of Medicine, Institute for Behavioral Medicine Research, 460 Medical Center Dr, Columbus, OH 43210, USA
    Psychol Sci 24:272-9. 2013
    ..The current study also extends attachment theory in an important new direction by demonstrating the utility of a psychoneuroimmunological approach to the study of attachment anxiety, stress, and health...
  32. doi request reprint Social support predicts inflammation, pain, and depressive symptoms: longitudinal relationships among breast cancer survivors
    Spenser Hughes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA Department of Psychology, The Ohio State University, Columbus, OH 43210, USA Electronic address
    Psychoneuroendocrinology 42:38-44. 2014
    ..Accordingly, the goal of the present study was to examine the relationships among survivors' social support, pain, depressive symptoms, and inflammation...
  33. ncbi request reprint Childhood adversity and herpesvirus latency in breast cancer survivors
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, Columbus, OH 43210, USA
    Health Psychol 32:337-44. 2013
    ....
  34. pmc Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 28:16-24. 2013
    ..This translational research broadens our understanding of the potential impact of the n-6:n-3 PUFA balance. ClinicalTrials.gov identifier: NCT00385723...
  35. pmc Adiponectin, leptin, and yoga practice
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 460 Medical Center Boulevard, Columbus, OH 43210, USA
    Physiol Behav 107:809-13. 2012
    ....
  36. pmc Altered expression of circadian rhythm genes among individuals with a history of depression
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, USA
    J Affect Disord 126:161-6. 2010
    ..The interaction of several circadian clock genes generates these daily circadian rhythms...
  37. pmc The influence of anger expression on wound healing
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 22:699-708. 2008
    ..This enhanced cortisol secretion was in turn related to longer time to heal. These findings suggest that the ability to regulate the expression of one's anger has a clinically relevant impact on wound healing...
  38. pmc Beta-blockers may reduce intrusive thoughts in newly diagnosed cancer patients
    Monica E Lindgren
    Institute for Behavioral Medicine Research, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Psychooncology 22:1889-94. 2013
    ..Thus, the current study examined the association between beta-blocker use and the severity of cancer-related intrusive thoughts and related symptoms following a cancer diagnosis...
  39. pmc Child maltreatment and breast cancer survivors: social support makes a difference for quality of life, fatigue and cancer stress
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, The Ohio State University, Columbus, OH 43210, United States
    Eur J Cancer 48:728-36. 2012
    ..To identify how child maltreatment is associated with quality of life (QOL) among breast cancer survivors...
  40. ncbi request reprint Depression and immune function: central pathways to morbidity and mortality
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    J Psychosom Res 53:873-6. 2002
    ..The increased morbidity and mortality associated with depression is substantial. In this paper, we review evidence suggesting that depression contributes to disease and death through immune dysregulation...
  41. ncbi request reprint The physiology of marriage: pathways to health
    Theodore F Robles
    Department of Psychology, The Ohio State University, 245 Townshend Hall, 1885 Neil Avenue, Columbus, OH 43210, USA
    Physiol Behav 79:409-16. 2003
    ..Finally, we discuss future implications of current research for understanding the relationships among marital functioning, physiology, and health...
  42. pmc Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk
    W James Waldman
    Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 22:215-23. 2008
    ....
  43. ncbi request reprint Stress-induced immune dysfunction: implications for health
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine and Public Health and Institute for Behavioral Medical Research, Ohio State University, Columbus, OH 43210, USA
    Nat Rev Immunol 5:243-51. 2005
    ..PNI researchers have used animal and human models to learn how the immune system communicates bidirectionally with the central nervous and endocrine systems and how these interactions impact on health...
  44. pmc Stress, food, and inflammation: psychoneuroimmunology and nutrition at the cutting edge
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210 1228, USA
    Psychosom Med 72:365-9. 2010
    ..A better understanding of how stressors, negative emotions, and unhealthy meals work together to enhance inflammation will benefit behavioral and nutritional research, as well as the broader biomedical community...
  45. pmc Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor
    Heather M Derry
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH, USA Department of Psychology, The Ohio State University, Columbus, OH, USA Electronic address
    Psychoneuroendocrinology 38:2676-85. 2013
    ..Accordingly, responses to stressors may be a possible mechanistic link among SSS, stress, and health...
  46. pmc Depressive symptoms enhance stress-induced inflammatory responses
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 31:172-6. 2013
    ..These findings add to our emerging understanding of the complex interactions among stress, depression, and immune dysregulation, and provide one potential pathway to explain relationships between depressive symptoms and disease...
  47. pmc The impact of psychological stress on wound healing: methods and mechanisms
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, 225 Psychology Building, 1835 Neil Avenue, Columbus, OH 43210, USA
    Immunol Allergy Clin North Am 31:81-93. 2011
    ..Translational work is needed to develop innovative treatments able to attenuate stress-induced delays in wound healing...
  48. pmc Stress, age, and immune function: toward a lifespan approach
    Jennifer E Graham
    Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    J Behav Med 29:389-400. 2006
    ..An understanding of the interactive effects of stress and age is critical to efforts to determine underlying mechanisms, clarify the directionality of effects, and develop effective interventions in early and late life...
  49. pmc Stress and wound healing
    Lisa M Christian
    Department of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Neuroimmunomodulation 13:337-46. 2006
    ..Moreover, specific physiological mechanisms are associated with certain types of interventions. In future research, an increased focus on mechanisms will help to more clearly elucidate pathways linking stress and healing processes...
  50. ncbi request reprint Examining psychosocial factors related to cancer incidence and progression: in search of the silver lining
    Kathi L Heffner
    Department of Psychiatry, The Ohio State University College of Medicine, 1581 Dodd Drive, McCampbell Hall, Columbus 43210, USA
    Brain Behav Immun 17:S109-11. 2003
  51. pmc Marital distress prospectively predicts poorer cellular immune function
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 614, United States
    Psychoneuroendocrinology 38:2713-9. 2013
    ..The current study filled an important gap in the literature by examining the ability of marital distress to prospectively predict immune alterations over a two-year period...
  52. pmc Stressful early life experiences and immune dysregulation across the lifespan
    Christopher P Fagundes
    The Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Comprehensive Cancer Center, OH, United States
    Brain Behav Immun 27:8-12. 2013
    ..We propose a model outlining potential biobehavioral pathways that explain how early life stressors leave people vulnerable to these maladaptive outcomes. Finally, we suggest ideas for future work to test different aspects of this model...
  53. ncbi request reprint Exercise accelerates wound healing among healthy older adults: a preliminary investigation
    Charles F Emery
    Departments of Psychology and Internal Medicine, 1885 Neil Avenue, The Ohio State University, Columbus, OH 43210, USA
    J Gerontol A Biol Sci Med Sci 60:1432-6. 2005
    ..This study evaluated the effect of a 3-month exercise program on wound healing, neuroendocrine function, and perceived stress among healthy older adults...
  54. pmc Sympathetic and parasympathetic activity in cancer-related fatigue: more evidence for a physiological substrate in cancer survivors
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, The Ohio State University, Columbus, OH 43210 1228, USA
    Psychoneuroendocrinology 36:1137-47. 2011
    ..Furthermore, lower HRV and elevated norepinephrine have been associated with a number of adverse health outcomes; accordingly, fatigue may also signal the need for increased vigilance to other health threats...
  55. pmc Attachment avoidance predicts inflammatory responses to marital conflict
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University 43210, USA
    Brain Behav Immun 23:898-904. 2009
    ..In sum, these results suggest that attachment avoidance modulates marital behavior and stress-induced immune dysregulation...
  56. pmc Social support and socioeconomic status interact to predict Epstein-Barr virus latency in women awaiting diagnosis or newly diagnosed with breast cancer
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University, College of Medicine, 460 Medical Center Drive, Columbus, OH 43210, USA
    Health Psychol 31:11-9. 2012
    ..This study assessed the joint impact of SES and social support on the expression of a latent herpesvirus, Epstein-Barr virus (EBV), in a group of highly stressed women...
  57. ncbi request reprint Depressive symptoms and lymphocyte proliferation in older adults
    Lynanne McGuire
    Division of Health Psychology, Department of Psychiatry, Ohio State University College of Medicine, USA
    J Abnorm Psychol 111:192-7. 2002
    ..These findings extend the association between depression and immune function to community-dwelling older adults with chronic, mild depressive symptoms...
  58. ncbi request reprint Stress-related modulation of matrix metalloproteinase expression
    Eric V Yang
    Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, 2175 Graves Hall, 333 W 10th Avenue, Columbus, OH 43210, USA
    J Neuroimmunol 133:144-50. 2002
    ..The data suggest that activation of the HPA and SAM axes, even in individuals within the normal range of depressive symptoms, could mediate MMP levels and wound healing in blister wounds...
  59. pmc Tumor site immune markers associated with risk for subsequent basal cell carcinomas
    Ronald Glaser
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, Ohio, United States of America
    PLoS ONE 6:e25160. 2011
    ..Basal cell carcinoma (BCC) tumors are the most common skin cancer and are highly immunogenic...
  60. ncbi request reprint Pain and wound healing in surgical patients
    Lynanne McGuire
    Psychology Department, University of Maryland Baltimore County, 21250, USA
    Ann Behav Med 31:165-72. 2006
    ..Human and animal laboratory studies have shown that stress delays healing of standardized punch biopsy wounds...
  61. ncbi request reprint Stress-related immune changes in middle-aged and older women: 1-year consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix 85069 7100, USA
    Health Psychol 21:321-31. 2002
    ..Results support longitudinal study of psychosocial context effects on tonic immune function and posttask scores...
  62. ncbi request reprint Toward optimal health: Janice K. Kiecolt-Glaser, Ph.D. and Rachel Yehuda, Ph.D. discuss chronic stress in women. Interview by Jodi R. Godfrey
    Janice K Kiecolt-Glaser
    J Womens Health (Larchmt) 14:294-8. 2005
  63. ncbi request reprint Older spouses' cortisol responses to marital conflict: associations with demand/withdraw communication patterns
    Kathi L Heffner
    Department of Psychology, Ohio University, Athens, OH 45701, USA
    J Behav Med 29:317-25. 2006
    ..Findings suggest that perceived communication patterns contribute to neuroendocrine responses to marital conflict, and implications for marriage and health research with older couples are discussed...
  64. ncbi request reprint Autonomic and glucocorticoid associations with the steady-state expression of latent Epstein-Barr virus
    John T Cacioppo
    University of Chicago, Illinois, USA
    Horm Behav 42:32-41. 2002
    ..Together, these studies raise the possibility that differences in the kinetics of glucocorticoid concentrations may contribute to differences in the reactivation of latent EBV...
  65. ncbi request reprint Neuroendocrine and cardiovascular reactivity to stress in mid-aged and older women: long-term temporal consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix, Arizona 85069, USA
    Psychophysiology 40:358-69. 2003
    ..65); consistency for other variables was moderate to low (rs approximately equal to .1-.4). Means of most variables changed from year to year. Results support the use of baseline, stressor, and posttask values in longitudinal studies...
  66. pmc Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients
    Amanda K Damjanovic
    Laboratory of Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    J Immunol 179:4249-54. 2007
    ..These findings demonstrate that chronic stress is associated with altered T cell function and accelerated immune cell aging as suggested by excessive telomere loss...

Research Grants7

  1. Psychoneuroimmunology and Mind-Body Medicine
    Janice Kiecolt Glaser; Fiscal Year: 2005
    ..Accordingly, a psychoneuroimmunology focus for these mechanistic studies will provide a way to clarify mechanisms while assessing clinical efficacy. ..
  2. Psychoneuroimmunology and Mind-Body Interventions
    Janice Kiecolt Glaser; Fiscal Year: 2006
    ....
  3. Aging, Stress, Fatty Acids and Inflammation
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ....
  4. Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and Distress
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ....
  5. Depression, Stress, Aging & Proinflammatory Cytokines
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ..The proposed study will expand our knowledge of how genetic polymorphisms interact with environmental stressors to enhance risk for adverse mental and physical health changes. ..
  6. Stress and Proinflammatory Cytokines: Omega-3 Intervention
    Janice Kiecolt Glaser; Fiscal Year: 2007
    ....